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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRAPPC9 Gene

protein-coding   GIFtS: 52
GCID: GC08M140742

Trafficking Protein Particle Complex 9

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Trafficking Protein Particle Complex 91 2     Tularik Gene 11
NIBP2 3 5     IBP2
TRAPP 120 KDa Subunit1 2     IKBKBBP2
Tularik Gene 1 Protein2 3     TRS1202
NIK- And IKBKB-Binding Protein2 3     IKK2 Binding Protein2
MRT132 5     NIK And IKK-Beta Binding Protein2
KIAA18823 5     Trafficking Protein Particle Complex Subunit 92

External Ids:    HGNC: 308321   Entrez Gene: 836962   Ensembl: ENSG000001676327   OMIM: 6119665   UniProtKB: Q96Q053   

Export aliases for TRAPPC9 gene to outside databases

Previous GC identifers: GC00U913619 GC08M140813 GC08M136053


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRAPPC9 Gene:
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been
associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been
described.(provided by RefSeq, Feb 2010)

GeneCards Summary for TRAPPC9 Gene: 
TRAPPC9 (trafficking protein particle complex 9) is a protein-coding gene. Diseases associated with TRAPPC9 include peripartum cardiomyopathy, and mental retardation.

UniProtKB/Swiss-Prot: TPPC9_HUMAN, Q96Q05
Function: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May
function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to
Golgi




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NT_008046.16  NC_018919.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRAPPC9 gene promoter:
         Max1   Bach2   Olf-1   CUTL1   Max   AREB6   SEF-1 (1)   En-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TRAPPC9 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRAPPC9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAPPC9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24.3

TRAPPC9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAPPC9 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M140742:  view genomic region     (about GC identifiers)

Start:
140,742,586 bp from pter      End:
141,468,678 bp from pter
Size:
726,093 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TPPC9_HUMAN, Q96Q05 (See protein sequence)
Recommended Name: Trafficking protein particle complex subunit 9  
Size: 1148 amino acids; 128530 Da
Subunit: Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least
TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12.
Directly interacts with IKBKB and MAP3K14
Subcellular location: Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity).
Cytoplasm (By similarity). Note=Processes and cell bodies of neurons (By similarity)
Sequence caution: Sequence=AAH06206.3; Type=Erroneous initiation; Sequence=BAB55299.1; Type=Erroneous initiation;
Sequence=BAB67775.1; Type=Erroneous initiation;
Secondary accessions: Q4VTT3 Q658K7 Q6P149 Q6ZQT3 Q7L5C4 Q86Y21 Q96SL2 Q9BQA2
Alternative splicing: 3 isoforms:  Q96Q05-1   Q96Q05-2   Q96Q05-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRAPPC9: NX_Q96Q05

Explore proteomics data for TRAPPC9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96Q05

  • TRAPPC9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRAPPC9 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001153844.1  NP_113654.4  

    ENSEMBL proteins: 
     ENSP00000373979   ENSP00000430116   ENSP00000405060   ENSP00000373978  

    Human Recombinant Protein Products for TRAPPC9: 
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    Cloud-Clone Corp. Proteins for TRAPPC9 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--

    TRAPPC9 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRAPPC: Trafficking protein particle complex

    1 InterPro protein domain:
     IPR013935 TRAPP_II_complex_Trs120

    Graphical View of Domain Structure for InterPro Entry Q96Q05

    ProtoNet protein and cluster: Q96Q05

    UniProtKB/Swiss-Prot: TPPC9_HUMAN, Q96Q05
    Similarity: Belongs to the NIBP family


    TRAPPC9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TPPC9_HUMAN, Q96Q05
    Function: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May
    function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to
    Golgi

    Animal Models:

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRAPPC9 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRAPPC9

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/6 Interacting proteins for TRAPPC9 (Q96Q052, 3 ENSP000003739794) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAPPC3O436172, 3, ENSP000003622614MINT-6784879 I2D: score=1 STRING: ENSP00000362261
    ARF6P623303I2D: score=4 
    SMARCB1Q128243I2D: score=4 
    TECPR1Q7Z6L13I2D: score=1 
    RAB3IPENSP000003680864STRING: ENSP00000368086
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030154cell differentiation IEA--

    TRAPPC9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRAPPC9 (TPPC9)

    Search CenterWatch for drugs/clinical trials and news about TRAPPC9 / TPPC9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRAPPC9 gene (2 alternative transcripts): 
    NM_001160372.1  NM_031466.5  

    Unigene Cluster for TRAPPC9:

    Trafficking protein particle complex 9
    Hs.654911  [show with all ESTs]
    Unigene Representative Sequence: BX647286
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389328(uc003yvh.2) ENST00000520857 ENST00000438773(uc003yvj.2)
    ENST00000521667(uc010mel.1) ENST00000522504 ENST00000521700 ENST00000519482
    ENST00000524162 ENST00000523777 ENST00000518723 ENST00000517667 ENST00000520532
    ENST00000518839 ENST00000521167 ENST00000521944 ENST00000389327(uc003yvi.1)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidTRAPPC9 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TRAPPC9
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAPPC9

    Additional mRNA sequence: 

    AB067469.1 AK026394.1 AK027689.1 AK128755.1 AK130220.1 AK308815.1 AL833973.1 AY190606.1 
    AY630619.1 BC003650.2 BC006206.2 BC065288.1 BX647286.1 

    8 DOTS entries:

    DT.95373752  DT.95373753  DT.310914  DT.40261865  DT.101976855  DT.100778729  DT.95220458  DT.95373754 

    24/105 AceView cDNA sequences (see all 105):

    AI915121 BI711422 AL535422 BC003650 AI380590 AI623559 BE274202 AW291962 
    AW449982 BE274279 AY190606 AL833973 CK903273 BC065288 AK128755 BI861671 
    BU070600 BQ637945 BI758298 CB128313 NM_031466 BE385106 BF726355 BU180775 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC9    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:        -                                                                                                           -                             -     -   
    SP2:                                                                                                                    -                             -     -   
    SP3:                                      -                                                                             -                             -     -   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 25 ^ 26 ^ 27
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for TRAPPC9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRAPPC9 expression in normal human tissues (normalized intensities)      TRAPPC9 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGCAAGCA
    TRAPPC9 Expression
    About this image


    TRAPPC9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             umbilical cord reticulocytes   
     
     Testis (Reproductive System)
             Testis Somatic Cells Primitive Gonad
     
     Umbilical Cord (Extraembryonic Tissues)
             umbilical cord reticulocytes   
     
     Gonad (Reproductive System)
             Testis Somatic Cells Primitive Gonad

    See TRAPPC9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRAPPC9

    SOURCE GeneReport for Unigene cluster: Hs.654911

    UniProtKB/Swiss-Prot: TPPC9_HUMAN, Q96Q05
    Tissue specificity: Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and
    placenta

        SABiosciences Custom PCR Arrays for TRAPPC9
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAPPC9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TRAPPC9 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trappc91 , 5 trafficking protein particle complex 91, 5 84.37(n)1
    92.63(a)1
      15 (33.70 cM)5
    765101  NM_180662.21  NP_850993.21 
     725896215 
    chicken
    (Gallus gallus)
    Aves TRAPPC91 trafficking protein particle complex 9 77.64(n)
    87.46(a)
      420312  XM_418422.2  XP_418422.2 
    lizard
    (Anolis carolinensis)
    Reptilia TRAPPC96
    trafficking protein particle complex 9
    89(a)
    1 ↔ 1
    4(15677183-15790531)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685672 hypothetical protein MGC68567 76.5(n)    BC060403.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000026301 uncharacterized LOC100002630 72.88(n)
    77.68(a)
      100002630  XM_003200528.1  XP_003200576.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bru1 brunelleschi 47.43(n)
    36.04(a)
      35325  NM_136200.2  NP_610044.2 
    worm
    (Caenorhabditis elegans)
    Secernentea C35C5.61 Protein C35C5.6 39.38(n)
    27.32(a)
      181345  NM_077532.2  NP_509933.1 


    ENSEMBL Gene Tree for TRAPPC9 (if available)
    TreeFam Gene Tree for TRAPPC9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/16222 SNPs in TRAPPC9 are shown (see all 16222)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2676071371,2
    Cpathogenic1141642301(-) CCTCCC/TGAAGG 4 R * stg10--------
    rs3732898291,2
    C--140747901(+) TTTTT-/G/T/TT
            
    TTTGT
    2 -- int10--------
    rs1386231161,2
    C--140759728(+) CAGGT-/GGGGAG 2 -- int10--------
    rs715202271,2
    C--140760320(+) CAGGTG/-GGGAG 2 -- int11Minor allele frequency- -:0.50NA 2
    rs715146341,2
    C,F--140760367(+) CAGCAG/AGTGTC 2 -- int11Minor allele frequency- A:0.50NA 2
    rs346635391,2
    C--140760688(+) GTGCA-/GGGATC 2 -- int10--------
    rs569160881,2
    C--140760724(+) GCAGGA/G/TGTCAG 2 -- int10--------
    rs3705878441,2
    C--140765317(+) CCATC-/ATC   
      C
    /TCCA
    TCCAT
    2 -- int10--------
    rs715146461,2
    C,F--140767672(+) ATGAGG/AACAGC 2 -- int12Minor allele frequency- A:0.33NA CSA 3
    rs1133304081,2
    C--140767738(+) CAGGGT/ATGGGG 2 -- int11Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for TRAPPC9 (140742586 - 140992586 bp, first 250kb of TRAPPC9)

    Structural Variations
         Database of Genomic Variants (DGV) 10/91 variations for TRAPPC9 (see all 91):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2737736CNV Deletion23290073
    esv2737735CNV Deletion23290073
    esv2737753CNV Deletion23290073
    esv2678434CNV Deletion23128226
    dgv1276e201CNV Deletion23290073
    esv2737756CNV Deletion23290073
    esv2678498CNV Deletion23128226
    esv2323808CNV Deletion18987734
    esv1759028CNV Deletion17803354
    esv1029437CNV Deletion17803354


    Human Gene Mutation Database (HGMD): TRAPPC9
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611966   
    OMIM disorders: 613192  
    UniProtKB/Swiss-Prot: TPPC9_HUMAN, Q96Q05
  • Mental retardation, autosomal recessive 13 (MRT13) [MIM:613192]: A disorder characterized by
    significantly below average general intellectual functioning associated with impairments in adaptative behavior
    and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the
    presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected
    individuals. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 7 diseases for TRAPPC9:    About MalaCards
    peripartum cardiomyopathy    mental retardation    microcephaly    intellectual disability
    kidney disease    cerebritis    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for TRAPPC9:
    Microcephaly     Intellectual disability

    TRAPPC9 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRAPPC9
    Human Genome Epidemiology (HuGE) Navigator: TRAPPC9 (4 documents)

    Export disorders for TRAPPC9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRAPPC9 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with TRAPPC9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2, 3 Nagase T....Ohara O. (2001)
    2. C4orf41 and TTC-15 are mammalian TRAPP components wit h a role at an early stage in ER-to-Golgi trafficking. (PubMed id 21525244)1, 2 Scrivens P.J....Sacher M. (2011)
    3. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    6. Identification of mutations in TRAPPC9, which encodes the NIK- and IKK-beta-binding protein, in nonsyndromic autosomal-recessive men tal retardation. (PubMed id 20004765)1, 2 Mir A....Vincent J.B. (2009)
    7. A truncating mutation of TRAPPC9 is associated with a utosomal-recessive intellectual disability and postnatal microcephaly. (PubMed id 20004763)1, 2 Mochida G.H....Walsh C.A. (2009)
    8. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (2009)
    9. NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF- (kappa)B activation. (PubMed id 15951441)1, 2 Hu W.-H.... Bethea J.R. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83696 HGNC: 30832 AceView: T1 Ensembl:ENSG00000167632 euGenes: HUgn83696
    ECgene: TRAPPC9 H-InvDB: TRAPPC9

    (According to HUGE)
    About This Section
    HUGE: KIAA1882

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRAPPC9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRAPPC9 gene:
    Search GeneIP for patents involving TRAPPC9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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