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TRAPPC8 Gene

protein-coding   GIFtS: 50
GCID: GC18M029409

Trafficking Protein Particle Complex 8

(Previous name: KIAA1012)
(Previous symbol: KIAA1012)
  Search for TRAPPC8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Trafficking Protein Particle Complex 81 2     HsT27062
KIAA10121 2 3 5     TRS852
Protein TRS85 Homolog2 3     General Sporulation Gene 1 Homolog2
General Sporulation Gene 1 Homolog (S. Cerevisiae)1     Trafficking Protein Particle Complex Subunit 82
GSG12     

External Ids:    HGNC: 291691   Entrez Gene: 228782   Ensembl: ENSG000001533397   OMIM: 6141365   UniProtKB: Q9Y2L53   

Export aliases for TRAPPC8 gene to outside databases

Previous GC identifers: GC00U913618 GC18M026266


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRAPPC8 Gene:
TRAPPC8 (trafficking protein particle complex 8) is a protein-coding gene.

UniProtKB/Swiss-Prot: TPPC8_HUMAN, Q9Y2L5
Function: May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage

Gene Wiki entry for TRAPPC8 (KIAA1012) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TRAPPC8
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAPPC8 promoter sequence
   Search Chromatin IP Primers for TRAPPC8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRAPPC8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12.1   Ensembl cytogenetic band:  18q12.1   HGNC cytogenetic band: 18q12.1

TRAPPC8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAPPC8 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M029409:  view genomic region     (about GC identifiers)

Start:
29,409,136 bp from pter      End:
29,533,099 bp from pter
Size:
123,964 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TPPC8_HUMAN, Q9Y2L5 (See protein sequence)
Recommended Name: Trafficking protein particle complex subunit 8  
Size: 1435 amino acids; 160997 Da
Subunit: Component of the multisubunit TRAPP (transport protein particle) complex, which includes TRAPPC2,
TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12
Sequence caution: Sequence=AAI27110.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI27111.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA76856.2;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAG50957.1; Type=Erroneous
initiation; Note=Translation N-terminally extended;
Secondary accessions: A0JP15 B3KME5 Q9H0L2
Alternative splicing: 2 isoforms:  Q9Y2L5-1   Q9Y2L5-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRAPPC8: NX_Q9Y2L5

Explore proteomics data for TRAPPC8 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys1288
  • Modification sites at PhosphoSitePlus

  • See TRAPPC8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055754.2  
    ENSEMBL proteins: 
     ENSP00000283351   ENSP00000462550   ENSP00000463764   ENSP00000463876   ENSP00000463139  
     ENSP00000464591   ENSP00000463973  

    TRAPPC8 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRAPPC8

     
    Search eBioscience for Proteins for TRAPPC8 

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    TRAPPC8 Assay Products:

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    Search eBioscience for ELISAs for TRAPPC8 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRAPPC: Trafficking protein particle complex

    2 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR024420 TRAPP_III_complex_Trs85

    Graphical View of Domain Structure for InterPro Entry Q9Y2L5

    ProtoNet protein and cluster: Q9Y2L5

    UniProtKB/Swiss-Prot: TPPC8_HUMAN, Q9Y2L5
    Similarity: Belongs to the TRS85 family


    Find genes that share domains with TRAPPC8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TPPC8_HUMAN, Q9Y2L5
    Function: May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with TRAPPC8           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TRAPPC8:
     Decreased p24 protein expressi 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRAPPC8
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRAPPC8

    miRNA
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    miRTarBase miRNAs that target TRAPPC8:
    hsa-mir-877-3p (MIRT037184)

    Block miRNA regulation of human, mouse, rat TRAPPC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRAPPC8 (see all 73):
    hsa-miR-607 hsa-miR-3607-3p hsa-miR-4272 hsa-miR-200a hsa-miR-128 hsa-miR-374a hsa-miR-138-2* hsa-miR-3142
    SwitchGear 3'UTR luciferase reporter plasmidTRAPPC8 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRAPPC8

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: TRAPPC8 (NM_014939)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRAPPC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC8

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAPPC8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TPPC8_HUMAN, Q9Y2L5: Golgi apparatus, cis-Golgi network (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus3
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0005801cis-Golgi network ----

    Find genes that share ontologies with TRAPPC8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAPPC8
    Interactions:

        Search GeneGlobe Interaction Network for TRAPPC8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRAPPC8 (Q9Y2L53 ENSP000002833514) via UniProtKB, MINT, STRING, and/or I2D (see all 95)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TECPR1Q7Z6L13, ENSP000004049234I2D: score=3 STRING: ENSP00000404923
    TRAPPC3O436173, ENSP000003622614I2D: score=1 STRING: ENSP00000362261
    TRAPPC13A5PLN93, ENSP000004092314STRING: ENSP00000409231 I2D: score=1 
    TRAPPC2LQ9UL333, ENSP000003010214I2D: score=1 STRING: ENSP00000301021
    EIF3LQ9Y2623I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006888ER to Golgi vesicle-mediated transport ----
    GO:0016192vesicle-mediated transport IEA--

    Find genes that share ontologies with TRAPPC8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRAPPC8 (TPPC8)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRAPPC8 gene: 
    NM_014939.3  

    Unigene Cluster for TRAPPC8:

    Trafficking protein particle complex 8
    Hs.202001  [show with all ESTs]
    Unigene Representative Sequence: NM_014939
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283351(uc002kxb.4 uc002kxc.4 uc002kxd.4) ENST00000580104
    ENST00000582509 ENST00000582539 ENST00000581057 ENST00000584604 ENST00000578886
    ENST00000578252 ENST00000577474 ENST00000582513(uc021uio.1 uc002kxe.2)
    ENST00000578658 ENST00000584876 ENST00000577426
    miRNA
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    Block miRNA regulation of human, mouse, rat TRAPPC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TRAPPC8 (see all 73):
    hsa-miR-607 hsa-miR-3607-3p hsa-miR-4272 hsa-miR-200a hsa-miR-128 hsa-miR-374a hsa-miR-138-2* hsa-miR-3142
    SwitchGear 3'UTR luciferase reporter plasmidTRAPPC8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TRAPPC8
    Predesigned siRNA for gene silencing in human, mouse, rat TRAPPC8
    Clone
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    OriGene clones in human, mouse for TRAPPC8 (see all 7)
    OriGene ORF clones in mouse, rat for TRAPPC8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRAPPC8 (NM_014939)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRAPPC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC8
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TRAPPC8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRAPPC8
      QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC8
      QuantiFast Probe-based Assays in human, mouse, rat TRAPPC8

    Additional mRNA sequence: 

    AB023229.1 AK001662.1 AK292537.1 BC059380.1 BC127109.1 BC127110.1 

    16 DOTS entries:

    DT.100730208  DT.92429088  DT.100754471  DT.101966440  DT.438190  DT.99998714  DT.121091526  DT.91842883 
    DT.95117194  DT.100754472  DT.121091547  DT.92429087  DT.91875385  DT.92429090  DT.95116066  DT.100019949 

    Selected AceView cDNA sequences (see all 140):

    BU520994 AI873828 AW137286 CD368790 AA287708 AU132862 BX500037 AL136749 
    AI220374 CA391217 AL041135 T35356 AW751570 AK001662 NM_014939 AL041590 
    CD654662 AA112168 AL043322 AA553615 AI942382 BM682428 AW197187 BQ008534 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC8 (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:              -                                                                 -                 -                             -                           
    SP2:              -                                                                 -                                                                           
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27a · 27b ^ 28 ^ 29 ^ 30 ^ 31 ^ 32a · 32b · 32c · 32d
    SP1:              -                                   -           -                                 
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:                                                                                                
    SP5:                                                              -                                 


    ECgene alternative splicing isoforms for TRAPPC8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRAPPC8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCATAATAC
    TRAPPC8 Expression
    About this image

    TRAPPC8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRAPPC8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.202001
        Custom PCR Arrays for TRAPPC8
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRAPPC8
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    QuantiFast Probe-based Assays in human, mouse, rat TRAPPC8
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAPPC8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TRAPPC8 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trappc81 , 5 trafficking protein particle complex 81, 5 88.63(n)1
    91.98(a)1
      18 (11.53 cM)5
    759641  NM_177038.31  NP_796012.21 
     208172245 
    chicken
    (Gallus gallus)
    Aves TRAPPC81 trafficking protein particle complex 8 80.97(n)
    85.65(a)
      421095  XM_003640812.2  XP_003640860.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAPPC86
    trafficking protein particle complex 8
    79(a)
    1 ↔ 1
    GL343207.1(3478335-3574256)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC060750.12   -- 75.89(n)    BC060750.1 
    zebrafish
    (Danio rerio)
    Actinopterygii trappc81 trafficking protein particle complex 8 63.69(n)
    69.12(a)
      570167  XM_001920683.4  XP_001920718.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(3)76BDm1 lethal (3) 76BDm 44.64(n)
    35.77(a)
      40140  NM_001275129.1  NP_001262058.1 
    worm
    (Caenorhabditis elegans)
    Secernentea trpp-86
    Protein F46F11.9, isoform a (F46F11.9) mRNA, compl...
    22(a)
    1 ↔ 1
    I(5610374-5616402) WBGene00018512
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G162801 AT5G16280 44.74(n)
    31.64(a)
      831488  NM_121633.4  NP_197132.2 
    rice
    (Oryza sativa)
    Liliopsida Os03g07869001 Os03g0786900 45.31(n)
    31.29(a)
      4334355  NM_001058028.1  NP_001051493.1 


    ENSEMBL Gene Tree for TRAPPC8 (if available)
    TreeFam Gene Tree for TRAPPC8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRAPPC8 gene
    1 SIMAP similar gene for TRAPPC8 using alignment to 7 protein entries:     TPPC8_HUMAN (see all proteins):
    KIAA1012

    Find genes that share paralogs with TRAPPC8           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRAPPC8 (see all 2665)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362704
    A breast cancer sample4--see VAR_0362702 R Q mis40--------
    rs1407445971,2
    --29408720(+) ATGCTA/GGTTGA 1 -- ds50010--------
    rs1458487171,2
    --29408849(+) CAGGAA/GTATTT 1 -- ds50010--------
    rs1378872181,2
    --29408876(+) CTACTC/TGTTAC 1 -- ds50010--------
    rs744497211,2
    C,F--29408885(+) ACAGCT/AACAAA 1 -- ds50012Minor allele frequency- A:0.03WA NA 238
    rs1423138451,2
    --29409060(+) GAATGC/TAGGGT 1 -- ds50010--------
    rs96753741,2
    C,F,H--29409169(+) GAGTGC/TTTTAT 1 -- ut3111Minor allele frequency- T:0.02NS EA NA WA 1380
    rs1911540241,2
    --29409215(+) TATAGC/TTTAAT 1 -- ut310--------
    rs177417961,2
    C,F,H--29409319(+) CTTGTC/TTTTCC 1 -- ut3122Minor allele frequency- T:0.28NA NS EA WA 2484
    rs1825264431,2
    --29409412(+) TTGTCC/TCACAC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TRAPPC8 (29409136 - 29533099 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TRAPPC8:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv990849CNV Deletion20482838
    esv1720728CNV Insertion17803354
    nsv131072CNV Loss16902084
    nsv2247CNV Loss18451855
    nsv820095CNV Loss19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRAPPC8
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614136    OMIM disorders: --


    Find genes that share disorders with TRAPPC8           About GenesLikeMe


    Export disorders for TRAPPC8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRAPPC8 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with TRAPPC8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    3. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. (PubMed id 21525244)1, 2 Scrivens P.J.... Sacher M. (Mol. Biol. Cell 2011)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Functional organization of the yeast proteome by systematic analysis of protein complexes. (PubMed id 11805826)1, 2 Gavin A.-C....Superti-Furga G. (Nature 2002)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    7. The adaptor function of TRAPPC2 in mammalian TRAPPs explains TRAPPC2-associated SEDT and TRAPPC9-associated congenital intellectual disability. (PubMed id 21858081)1 Zong M....Yu S. (PLoS ONE 2011)
    8. Organization and assembly of the TRAPPII complex. (PubMed id 21453443)1 Choi C....Conibear E. (Traffic 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22878 HGNC: 29169 AceView: KIAA1012 Ensembl:ENSG00000153339 euGenes: HUgn22878
    ECgene: TRAPPC8 H-InvDB: TRAPPC8

    (According to HUGE)
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    HUGE: KIAA1012

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRAPPC8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TRAPPC8 gene:
    Search GeneIP for patents involving TRAPPC8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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