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TRAPPC6B Gene

protein-coding   GIFtS: 52
GCID: GC14M039617

Trafficking Protein Particle Complex 6B

  Search for TRAPPC6B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Trafficking Protein Particle Complex 6B1 2
TPC62 5
Trafficking Protein Particle Complex Subunit 6B2

External Ids:    HGNC: 230661   Entrez Gene: 1225532   Ensembl: ENSG000001824007   OMIM: 6103975   UniProtKB: Q86SZ23   
ORGUL members:         

Export aliases for TRAPPC6B gene to outside databases

Previous GC identifers: GC14M037607 GC14M038686 GC14M019731


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRAPPC6B Gene:
TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport (Kummel et
al., 2005 (PubMed 16025134)).(supplied by OMIM, Mar 2008)

GeneCards Summary for TRAPPC6B Gene:
TRAPPC6B (trafficking protein particle complex 6B) is a protein-coding gene. An important paralog of this gene is TRAPPC6A.

UniProtKB/Swiss-Prot: TPC6B_HUMAN, Q86SZ2
Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRAPPC6B gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   oct-B2   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAPPC6B promoter sequence
   Search Chromatin IP Primers for TRAPPC6B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRAPPC6B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.1   Ensembl cytogenetic band:  14q21.1   HGNC cytogenetic band: 14q13.3

TRAPPC6B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAPPC6B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M039617:  view genomic region     (about GC identifiers)

Start:
39,617,015 bp from pter      End:
39,639,736 bp from pter
Size:
22,722 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TPC6B_HUMAN, Q86SZ2 (See protein sequence)
Recommended Name: Trafficking protein particle complex subunit 6B  
Size: 158 amino acids; 17983 Da
Subunit: Part of the multisubunit TRAPP (transport protein particle) complex. Homodimer. Heterodimer with TRAPPC3
Sequence caution: Sequence=CAD62341.1; Type=Erroneous initiation;
3 PDB 3D structures from and Proteopedia for TRAPPC6B:
2BJN (3D)        2CFH (3D)        3KXC (3D)    
Secondary accessions: B3KPS2 Q5JPD6 Q86U35 Q86X35
Alternative splicing: 2 isoforms:  Q86SZ2-1   Q86SZ2-2   

Explore the universe of human proteins at neXtProt for TRAPPC6B: NX_Q86SZ2

Explore proteomics data for TRAPPC6B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys109
  • Modification sites at PhosphoSitePlus

  • See TRAPPC6B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001073005.1  NP_803235.1  

    ENSEMBL proteins: 
     ENSP00000330289   ENSP00000335171   ENSP00000452236   ENSP00000450670   ENSP00000451711  

    TRAPPC6B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TRAPPC6B

     
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    LSBio Antibodies in human, mouse, rat for TRAPPC6B

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    Cloud-Clone Corp. ELISAs for TRAPPC6B
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRAPPC: Trafficking protein particle complex

    2 InterPro protein domains:
     IPR007194 TRAPP_component
     IPR024096 NO_sig/Golgi_transp_ligand-bd

    Graphical View of Domain Structure for InterPro Entry Q86SZ2

    ProtoNet protein and cluster: Q86SZ2

    1 Blocks protein domain: IPB007194 Transport protein particle (TRAPP) component

    UniProtKB/Swiss-Prot: TPC6B_HUMAN, Q86SZ2
    Similarity: Belongs to the TRAPP small subunits family. BET3 subfamily


    Find genes that share domains with TRAPPC6B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TPC6B_HUMAN, Q86SZ2
    Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18930054
         
    Find genes that share ontologies with TRAPPC6B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TRAPPC6B:
     Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRAPPC6B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRAPPC6B
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    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRAPPC6B (see all 32):
    hsa-miR-579 hsa-miR-34b* hsa-miR-328 hsa-miR-125a-5p hsa-miR-136 hsa-miR-3942-5p hsa-miR-500a hsa-miR-486-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRAPPC6B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRAPPC6B

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    GenScript: all cDNA clones in your preferred vector (see all 2): TRAPPC6B (NM_001079537)
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAPPC6B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TPC6B_HUMAN, Q86SZ2: Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus3
    cytosol2
    endoplasmic reticulum2
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--

    Find genes that share ontologies with TRAPPC6B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAPPC6B
    Interactions:

        Search GeneGlobe Interaction Network for TRAPPC6B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRAPPC6B (Q86SZ21, 2, 3 ENSP000003302894) via UniProtKB, MINT, STRING, and/or I2D (see all 58)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAPPC3O436171, 2, 3, ENSP000003622614EBI-6160531,EBI-743566 MINT-6785068 MINT-6785053 MINT-6784845 I2D: score=3 STRING: ENSP00000362261
    COPS5Q929053, ENSP000003505124I2D: score=5 STRING: ENSP00000350512
    TRAPPC4Q9Y2963, ENSP000003518964I2D: score=1 STRING: ENSP00000351896
    TRAPPC5Q8IUR03, ENSP000003169904I2D: score=1 STRING: ENSP00000316990
    TRAPPC2P0DI813, ENSP000003527084I2D: score=1 STRING: ENSP00000352708
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016192vesicle-mediated transport IEA--

    Find genes that share ontologies with TRAPPC6B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRAPPC6B (TPC6B)

    1 DrugBank Compound for TRAPPC6B    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    S-PALMITOYL-L-CYSTEINE-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRAPPC6B gene (2 alternative transcripts): 
    NM_001079537.1  NM_177452.3  

    Unigene Cluster for TRAPPC6B:

    Trafficking protein particle complex 6B
    Hs.13303  [show with all ESTs]
    Unigene Representative Sequence: NM_001079537
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000469361(uc001wut.1 uc001wuu.1 uc001wuv.1 uc010tqd.1)
    ENST00000330149 ENST00000347691 ENST00000557764 ENST00000555269 ENST00000554018
    ENST00000556765
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRAPPC6B (see all 32):
    hsa-miR-579 hsa-miR-34b* hsa-miR-328 hsa-miR-125a-5p hsa-miR-136 hsa-miR-3942-5p hsa-miR-500a hsa-miR-486-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRAPPC6B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRAPPC6B
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    GenScript: all cDNA clones in your preferred vector (see all 2): TRAPPC6B (NM_001079537)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC6B
    Primer
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    OriGene qPCR primer pairs and template standards for TRAPPC6B
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRAPPC6B
      QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC6B
      QuantiFast Probe-based Assays in human, mouse, rat TRAPPC6B

    Additional mRNA sequence: 

    AK025437.1 AK056690.1 AK294339.1 AK310730.1 AK315900.1 AL833179.1 BC047328.1 BX161510.1 
    BX248013.1 

    8 DOTS entries:

    DT.451669  DT.100790168  DT.92425367  DT.75171886  DT.100773795  DT.120757479  DT.120757494  DT.40122444 

    Selected AceView cDNA sequences (see all 150):

    AL833179 AA625846 BU735689 AI378461 BU626821 AI521496 AK025437 AA911836 
    CD676093 AI567135 CA422147 CR614282 AI216550 AI129609 BC047328 W49617 
    F01823 BX248013 AI366209 AA504210 Z40183 AW118812 AW273373 BX161510 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC6B    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b
    SP1:                    -     -                                                         
    SP2:                    -     -           -                 -     -                     
    SP3:                    -     -           -                                             
    SP4:                    -                 -                                             
    SP5:                                                                                    


    ECgene alternative splicing isoforms for TRAPPC6B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRAPPC6B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGGACAAG
    TRAPPC6B Expression
    About this image

    TRAPPC6B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRAPPC6B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.13303
        Custom PCR Arrays for TRAPPC6B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAPPC6B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TRAPPC6B gene from Selected species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trappc6b1 , 5 trafficking protein particle complex 6B1, 5 92.19(n)1
    97.47(a)1
      12 (25.99 cM)5
    782321  NM_030057.21  NP_084333.11 
     590430935 
    chicken
    (Gallus gallus)
    Aves TRAPPC6B1 trafficking protein particle complex 6B 83.97(n)
    94.3(a)
      423337  NM_001252160.1  NP_001239089.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAPPC6B6
    trafficking protein particle complex 6B
    94(a)
    1 ↔ 1
    1(23963820-23974564)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC526682 hypothetical protein MGC52668 78.85(n)    BC044077.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc663042 hypothetical protein MGC66304 75.02(n)   393634  BC057509.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG61961 CG6196 55.19(n)
    55.63(a)
      41866  NM_142193.4  NP_650450.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_K08H10.91 CELE_K08H10.9 52.28(n)
    48.2(a)
      179394  NM_073170.5  NP_505571.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRS33(YOR115C)4 One of 10 subunits of the transport protein particle more   --   15(539465-538659) 854282  NP_014758.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G050001 AT3G05000 59.02(n)
    54.92(a)
      819661  NM_111372.3  NP_187151.1 
    rice
    (Oryza sativa)
    Liliopsida Os07g02911001 Os07g0291100 57.92(n)
    54.92(a)
      4342949  NM_001065930.1  NP_001059395.1 


    ENSEMBL Gene Tree for TRAPPC6B (if available)
    TreeFam Gene Tree for TRAPPC6B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRAPPC6B gene
    TRAPPC6A2  
    1 SIMAP similar gene for TRAPPC6B using alignment to 5 protein entries:     TPC6B_HUMAN (see all proteins):
    TRAPPC6A

    Find genes that share paralogs with TRAPPC6B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRAPPC6B (see all 614)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs603420721,2
    C--39616610(+) ACCTCC/TGACTC 2 -- int10--------
    rs1406951201,2
    --39616618(+) CTCCCA/GGGTTC 2 -- int10--------
    rs786832191,2
    F--39616845(+) ATGTAT/CGGCAT 2 -- int11Minor allele frequency- C:0.14WA 118
    rs80112441,2
    C,F,A,H--39616856(+) taaggC/Taacaa 2 -- int110Minor allele frequency- T:0.26NS EA NA WA 752
    rs1446563691,2
    --39617030(+) TTCTTC/TAGTAC 2 -- ut310--------
    rs28691,2
    C,F,O,A,H--39617103(+) TTCAAT/CTGTCC 2 -- ut3127Minor allele frequency- C:0.20MN NS EA NA WA 2896
    rs171088521,2
    C,F--39617116(+) TACTAA/TTTTTT 2 -- ut314Minor allele frequency- T:0.09NA WA 252
    rs732915411,2
    C,F--39617195(+) TATACC/ACAAAG 2 -- ut313Minor allele frequency- A:0.20WA CSA 122
    rs745567591,2
    C,F--39617268(+) GATTGG/ATTAAT 2 -- ut311Minor allele frequency- A:0.14WA 118
    rs1146806511,2
    C,F--39617436(+) TGCTGG/CCAAAT 2 -- ut311Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for TRAPPC6B (39617015 - 39639736 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TRAPPC6B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670683CNV Deletion23128226
    esv27326CNV Loss19812545
    nsv85488CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610397    OMIM disorders: --


    Find genes that share disorders with TRAPPC6B           About GenesLikeMe

    Genetic Association Database (GAD): TRAPPC6B

    Export disorders for TRAPPC6B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRAPPC6B gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TRAPPC6B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex. (PubMed id 16025134)1, 2 Kuemmel D....Heinemann U. (EMBO Rep. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. (PubMed id 21525244)1 Scrivens P.J.... Sacher M. (Mol. Biol. Cell 2011)
    9. Distinct isocomplexes of the TRAPP trafficking factor coexist inside human cells. (PubMed id 18930054)1 KA1mmel D....Heinemann U. (FEBS Lett. 2008)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 122553 HGNC: 23066 AceView: TRAPPC6B Ensembl:ENSG00000182400 euGenes: HUgn122553
    ECgene: TRAPPC6B H-InvDB: TRAPPC6B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRAPPC6B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRAPPC6B gene:
    Search GeneIP for patents involving TRAPPC6B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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