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TRAPPC5 Gene

protein-coding   GIFtS: 47
GCID: GC19P007745

Trafficking Protein Particle Complex 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Trafficking Protein Particle Complex 51 2
TRS312
Trafficking Protein Particle Complex Subunit 52

External Ids:    HGNC: 230671   Entrez Gene: 1260032   Ensembl: ENSG000001810297   UniProtKB: Q8IUR03   

Export aliases for TRAPPC5 gene to outside databases

Previous GC identifers: GC19P007640 GC19P007651 GC19U900665 GC19P007415


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRAPPC5 Gene:
TRAPPC5 (trafficking protein particle complex 5) is a protein-coding gene. Diseases associated with TRAPPC5 include malaria, and alzheimer's disease.

UniProtKB/Swiss-Prot: TPPC5_HUMAN, Q8IUR0
Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRAPPC5 gene promoter:
         p300   ATF-2   c-Jun   AP-2alpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TRAPPC5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRAPPC5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.3

TRAPPC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAPPC5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P007745:  view genomic region     (about GC identifiers)

Start:
7,745,707 bp from pter      End:
7,747,748 bp from pter
Size:
2,042 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TPPC5_HUMAN, Q8IUR0 (See protein sequence)
Recommended Name: Trafficking protein particle complex subunit 5  
Size: 188 amino acids; 20783 Da
Subunit: Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least
TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12
Secondary accessions: A8K7I6

Explore the universe of human proteins at neXtProt for TRAPPC5: NX_Q8IUR0

Explore proteomics data for TRAPPC5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRAPPC5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001035926.1  NP_001035927.1  NP_777554.1  

    ENSEMBL proteins: 
     ENSP00000470262   ENSP00000316990   ENSP00000399025   ENSP00000470703  

    TRAPPC5 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for TRAPPC5
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    Cloud-Clone Corp. Proteins for TRAPPC5

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    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Cloud-Clone Corp. ELISAs for TRAPPC5
    Cloud-Clone Corp. CLIAs for TRAPPC5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRAPPC: Trafficking protein particle complex

    3 InterPro protein domains:
     IPR007194 TRAPP_component
     IPR016696 TRAPP-I_su5
     IPR024096 NO_sig/Golgi_transp_ligand-bd

    Graphical View of Domain Structure for InterPro Entry Q8IUR0

    ProtoNet protein and cluster: Q8IUR0

    1 Blocks protein domain: IPB007194 Transport protein particle (TRAPP) component

    UniProtKB/Swiss-Prot: TPPC5_HUMAN, Q8IUR0
    Similarity: Belongs to the TRAPP small subunits family. BET3 subfamily


    TRAPPC5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TPPC5_HUMAN, Q8IUR0
    Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TRAPPC5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TRAPPC5:
     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRAPPC5
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    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRAPPC5

    Gene Editing
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    Clone
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TPPC5_HUMAN, Q8IUR0: Golgi apparatus, cis-Golgi network (By similarity). Endoplasmic reticulum (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    endoplasmic reticulum2
    golgi apparatus2
    mitochondrion2
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--
    GO:0030008TRAPP complex IEA--

    TRAPPC5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAPPC5
    Interactions:

        Search GeneGlobe Interaction Network for TRAPPC5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRAPPC5 (Q8IUR03 ENSP000003169904) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAPPC4Q9Y2963, ENSP000003518964I2D: score=1 STRING: ENSP00000351896
    TRAPPC6BQ86SZ23, ENSP000003302894I2D: score=1 STRING: ENSP00000330289
    TRAPPC2P0DI813, ENSP000003527084I2D: score=5 STRING: ENSP00000352708
    TRAPPC3O436173, ENSP000003622614I2D: score=4 STRING: ENSP00000362261
    TRAPPC2P1P0DI823I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016192vesicle-mediated transport IEA--

    TRAPPC5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRAPPC5 (TPPC5)

    1 DrugBank Compound for TRAPPC5    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    S-PALMITOYL-L-CYSTEINE-- --target--10592235



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRAPPC5 gene (3 alternative transcripts): 
    NM_001042461.2  NM_001042462.1  NM_174894.2  

    Unigene Cluster for TRAPPC5:

    Trafficking protein particle complex 5
    Hs.432413  [show with all ESTs]
    Unigene Representative Sequence: BU856835
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000596148 ENST00000317378(uc002mhi.1 uc002mhj.1) ENST00000426877(uc002mhk.1)
    ENST00000595985
    miRNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC5
      QuantiFast Probe-based Assays in human, mouse, rat TRAPPC5

    Additional mRNA sequence: 

    AK292001.1 BC022836.1 BC042161.1 

    8 DOTS entries:

    DT.216673  DT.99982856  DT.91743797  DT.95090061  DT.100820643  DT.100027622  DT.97843586  DT.91743790 

    Selected AceView cDNA sequences (see all 310):

    AI590095 CA306472 BC035847 AA535983 AI802045 AI694061 AW135805 BU689568 
    CR622194 BM129686 AI075441 BM841451 AI279032 BM809462 AI127833 AI740448 
    BM129399 CD367335 AI870468 AI037887 BF002349 AI671423 BM841051 BU634406 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC5    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c
    SP1:        -     -                           
    SP2:                                          
    SP3:              -                           
    SP4:                                          


    ECgene alternative splicing isoforms for TRAPPC5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRAPPC5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCAAGTTCG
    TRAPPC5 Expression
    About this image

    TRAPPC5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRAPPC5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.432413
        Custom PCR Arrays for TRAPPC5
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TRAPPC5 gene from Selected species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trappc51 , 5 trafficking protein particle complex 51, 5 89.18(n)1
    98.94(a)1
      8 (1.92 cM)5
    666821  NM_025701.41  NP_079977.31 
     36762995 
    chicken
    (Gallus gallus)
    Aves TRAPPC51 trafficking protein particle complex 5 79.79(n)
    80.85(a)
      100858483  NM_001271159.1  NP_001258088.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAPPC56
    trafficking protein particle complex 5
    79(a)
    1 ↔ 1
    2(102876402-102876965)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.21952 Transcribed sequence with weak similarity to protein more 75.67(n)    AL859505.2 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc34a112 Transcribed sequences 75.22(n)    57055525 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG101531 CG10153 63(n)
    64.29(a)
      36641  NM_137142.4  NP_610986.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y57A10A.161 CELE_Y57A10A.16 53.79(n)
    53.41(a)
      190338  NM_064192.5  NP_496593.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRS31(YDR472W)4
    TRS311
    One of 10 subunits of the transport protein particle more4
    TRS311
    41.83(n)1
    34.31(a)1
      4(1403322-1404173)4
    8520831, 4  NP_010760.31  NP_010760.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G580301 AT5G58030 51.64(n)
    51.45(a)
      835915  NM_125188.3  NP_200611.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g07086001 Os01g0708600 52.83(n)
    53.8(a)
      4327685  NM_001050563.1  NP_001044028.1 


    ENSEMBL Gene Tree for TRAPPC5 (if available)
    TreeFam Gene Tree for TRAPPC5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRAPPC5 (see all 62)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs348691661,2
    C,F--7745243(+) ACACCA/GCCACA 3 -- us2k17Minor allele frequency- G:0.21NA CSA WA EA 366
    rs1164963451,2
    C,F--7745745(+) GCCGAG/ACAGAC 3 -- ut511Minor allele frequency- A:0.08WA 118
    rs1420645631,2
    --7745761(+) CGGTTC/TCTGGT 3 -- ut510--------
    rs1178675841,2
    C,F--7745784(+) ACCCCA/C/TCTGCC 5 -- int1 ut511NA 120
    rs38267391,2
    C,F--7745806(-) GGAGCG/AGACGA 3 -- int1 ut51 ese36Minor allele frequency- A:0.16NA WA EA 364
    rs1468071971,2
    C--7745821(+) CCCTT-/CCCCCG 3 -- int1 ut510--------
    rs1929932091,2
    --7746094(+) GGCCCA/GGAGCC 3 -- int10--------
    rs1852430461,2
    --7746188(+) GCATGA/GTGGGG 3 -- int10--------
    rs1431017871,2
    C--7746426(+) AGGACA/GAAGGG 3 -- int10--------
    rs1482232991,2
    C--7746516(+) ATCCCC/TCCTGT 3 -- int10--------

    HapMap Linkage Disequilibrium report for TRAPPC5 (7745707 - 7747748 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TRAPPC5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv910970CNV Loss21882294
    nsv833731CNV Loss17160897
    esv2751809CNV Gain17911159
    nsv833732CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRAPPC5
    DNA2.0 Custom Variant and Variant Library Synthesis for TRAPPC5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for TRAPPC5:    
    About MalaCards
    malaria    alzheimer's disease


    TRAPPC5 for disorders           About GeneDecksing


    Export disorders for TRAPPC5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRAPPC5 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TRAPPC5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. (PubMed id 21525244)1, 2 Scrivens P.J.... Sacher M. (Mol. Biol. Cell 2011)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. (PubMed id 21163940)1 Soler-LA^pez M....Aloy P. (Genome Res. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 126003 HGNC: 23067 AceView: LOC199675 Ensembl:ENSG00000181029 euGenes: HUgn126003
    ECgene: TRAPPC5 H-InvDB: TRAPPC5

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRAPPC5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRAPPC5 gene:
    Search GeneIP for patents involving TRAPPC5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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