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Aliases for TRAPPC3L Gene

Aliases for TRAPPC3L Gene

  • Trafficking Protein Particle Complex 3-Like 2 3
  • TRAPPC3-Like Protein 3 4
  • BET3-Like Protein 3 4
  • BET3L 3 4
  • Trafficking Protein Particle Complex Subunit 3-Like Protein 3
  • BET3 Like (S. Cerevisiae) 2
  • BA259P20.2 3
  • BET3L, 6

External Ids for TRAPPC3L Gene

Previous HGNC Symbols for TRAPPC3L Gene

  • BET3L

Previous GeneCards Identifiers for TRAPPC3L Gene

  • GC06M116817

Summaries for TRAPPC3L Gene

GeneCards Summary for TRAPPC3L Gene

TRAPPC3L (Trafficking Protein Particle Complex 3-Like) is a Protein Coding gene. An important paralog of this gene is TRAPPC3.

UniProtKB/Swiss-Prot for TRAPPC3L Gene

  • May play a role in vesicular transport from endoplasmic reticulum to Golgi.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAPPC3L Gene

Genomics for TRAPPC3L Gene

Genomic Location for TRAPPC3L Gene

Start:
116,494,989 bp from pter
End:
116,545,610 bp from pter
Size:
50,622 bases
Orientation:
Minus strand

Genomic View for TRAPPC3L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRAPPC3L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAPPC3L Gene

No data available for Regulatory Elements for TRAPPC3L Gene

Proteins for TRAPPC3L Gene

  • Protein details for TRAPPC3L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T215-TPC3L_HUMAN
    Recommended name:
    Trafficking protein particle complex subunit 3-like protein
    Protein Accession:
    Q5T215
    Secondary Accessions:
    • Q5T213
    • Q5T214

    Protein attributes for TRAPPC3L Gene

    Size:
    181 amino acids
    Molecular mass:
    20566 Da
    Quaternary structure:
    • Homodimer. Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2, TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12.

    Alternative splice isoforms for TRAPPC3L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TRAPPC3L Gene

Proteomics data for TRAPPC3L Gene at MOPED

Post-translational modifications for TRAPPC3L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRAPPC3L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRAPPC3L Gene

Domains for TRAPPC3L Gene

Graphical View of Domain Structure for InterPro Entry

Q5T215

UniProtKB/Swiss-Prot:

TPC3L_HUMAN :
  • Q5T215
Family:
  • Belongs to the TRAPP small subunits family. BET3 subfamily.
genes like me logo Genes that share domains with TRAPPC3L: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TRAPPC3L Gene

Function for TRAPPC3L Gene

Molecular function for TRAPPC3L Gene

UniProtKB/Swiss-Prot Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRAPPC3L Gene

Localization for TRAPPC3L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRAPPC3L Gene

Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.

Gene Ontology (GO) - Cellular Components for TRAPPC3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with TRAPPC3L: view

No data available for Subcellular locations from COMPARTMENTS for TRAPPC3L Gene

Pathways for TRAPPC3L Gene

SuperPathways for TRAPPC3L Gene

No Data Available

Interacting Proteins for TRAPPC3L Gene

Gene Ontology (GO) - Biological Process for TRAPPC3L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with TRAPPC3L: view

No data available for Pathways by source for TRAPPC3L Gene

Transcripts for TRAPPC3L Gene

mRNA/cDNA for TRAPPC3L Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRAPPC3L

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TRAPPC3L
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC3L Gene

No ASD Table

Relevant External Links for TRAPPC3L Gene

GeneLoc Exon Structure for
TRAPPC3L
ECgene alternative splicing isoforms for
TRAPPC3L

Expression for TRAPPC3L Gene

mRNA expression in normal human tissues for TRAPPC3L Gene

mRNA differential expression in normal tissues according to GTEx for TRAPPC3L Gene

This gene is overexpressed in Spleen (11.0).
genes like me logo Genes that share expressions with TRAPPC3L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for TRAPPC3L Gene

Orthologs for TRAPPC3L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TRAPPC3L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia BET3L 35
  • 99.63 (n)
  • 99.45 (a)
TRAPPC3L 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BET3L 35
  • 92.27 (n)
  • 93.92 (a)
TRAPPC3L 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TRAPPC3L 35
  • 91.16 (n)
  • 94.48 (a)
TRAPPC3L 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Bet3l 16
Trappc3l 35
  • 89.5 (n)
  • 92.82 (a)
Trappc3l 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TRAPPC3L 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TRAPPC3L 36
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Trappc3l 35
  • 88.58 (n)
  • 91.71 (a)
chicken
(Gallus gallus)
Aves BET3L 35
  • 72.04 (n)
  • 76.67 (a)
TRAPPC3L 36
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TRAPPC3L 36
  • 75 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488207 35
  • 64.79 (n)
  • 66.85 (a)
fruit fly
(Drosophila melanogaster)
Insecta Bet3 36
  • 47 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea trpp-3 36
  • 39 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes BET3 36
  • 44 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8333 36
  • 53 (a)
OneToMany
Species with no ortholog for TRAPPC3L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for TRAPPC3L Gene

ENSEMBL:
Gene Tree for TRAPPC3L (if available)
TreeFam:
Gene Tree for TRAPPC3L (if available)

Paralogs for TRAPPC3L Gene

Paralogs for TRAPPC3L Gene

Selected SIMAP similar genes for TRAPPC3L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRAPPC3L: view

Variants for TRAPPC3L Gene

Sequence variations from dbSNP and Humsavar for TRAPPC3L Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs952783 -- 116,523,368(+) TTCCT(A/G)TTGTA intron-variant
rs967806 -- 116,523,987(+) GATAT(C/T)TTTGA intron-variant
rs1051172 -- 116,519,703(+) AAGAG(A/G/T)AAAGG intron-variant
rs1051173 -- 116,519,720(+) GAATG(C/T)TCTTG intron-variant
rs1407073 -- 116,519,373(-) GCACA(C/G)TTGGG intron-variant

Relevant External Links for TRAPPC3L Gene

HapMap Linkage Disequilibrium report
TRAPPC3L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TRAPPC3L Gene

Disorders for TRAPPC3L Gene

No disorders were found for TRAPPC3L Gene.

No data available for UniProtKB/Swiss-Prot for TRAPPC3L Gene

Publications for TRAPPC3L Gene

  1. C4orf41 and TTC-15 are mammalian TRAPP components with a role at an early stage in ER-to-Golgi trafficking. (PMID: 21525244) Scrivens P.J. … Sacher M. (Mol. Biol. Cell 2011) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for TRAPPC3L Gene

Sources for TRAPPC3L Gene

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