Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRAPPC2L Gene

protein-coding   GIFtS: 45
GCID: GC16P088923

trafficking protein particle complex 2-like

 Explore 1 disease affiliated with
TRAPPC2L via our new
 Human Malady Compendium 
Biological research products
for TRAPPC2L
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Trafficking Protein Particle Complex 2-Like1 2
HSPC1761 2
Hematopoietic Stem/Progenitor Cells 1762
Trafficking Protein Particle Complex Subunit 2-Like Protein2

External Ids:    HGNC: 308871   Entrez Gene: 516932   Ensembl: ENSG000001675157   OMIM: 6109705   UniProtKB: Q9UL333   

Export aliases for TRAPPC2L gene to outside databases

Previous GC identifers: GC16P087452 GC16P074620


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: TPC2L_HUMAN, Q9UL33
Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010542.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRAPPC2L gene promoter:
         Max1   AML1a   Pax-5   NF-kappaB   GATA-1   IRF-2   NF-kappaB2   HOXA5   Pax-4a   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAPPC2L promoter sequence
   Search SABiosciences Chromatin IP Primers for TRAPPC2L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAPPC2L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3   Ensembl cytogenetic band:  16q24.3   HGNC cytogenetic band: 16q24.3

TRAPPC2L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAPPC2L gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P088923:  view genomic region     (about GC identifiers)

Start:
88,922,628 bp from pter      End:
88,929,094 bp from pter
Size:
6,467 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TPC2L_HUMAN, Q9UL33 (See protein sequence)
Recommended Name: Trafficking protein particle complex subunit 2-like protein  
Size: 140 amino acids; 16146 Da
Subunit: Component of the multisubunit TRAPP (transport protein particle) complex, which includes at least TRAPPC2,
TRAPPC2L, TRAPPC3, TRAPPC3L, TRAPPC4, TRAPPC5, TRAPPC8, TRAPPC9, TRAPPC10, TRAPPC11 and TRAPPC12. Interacts with the
heterodimer TRAPPC3-TRAPPC6A. Interacts with TRAPPC6A
Subcellular location: Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus
Sequence caution: Sequence=BAC86686.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: B2R4M9 Q6ZTA7 Q9NZZ4
Alternative splicing: 2 isoforms:  Q9UL33-1   Q9UL33-2   

Explore the universe of human proteins at neXtProt for TRAPPC2L: NX_Q9UL33

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UL33

  • TRAPPC2L Protein expression data from MOPED and PaxDb:    About this image 
    TRAPPC2L Protein Expression
    REFSEQ proteins: NP_057293.1  
    ENSEMBL proteins: 
     ENSP00000455447   ENSP00000457684   ENSP00000301021   ENSP00000455273   ENSP00000455100  
     ENSP00000454927   ENSP00000455235   ENSP00000457728   ENSP00000455392   ENSP00000455892  

    Human Recombinant Protein Products for TRAPPC2L: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: TRAPPC2L
    OriGene Protein Over-expression Lysate: TRAPPC2L
    OriGene Custom Protein Services for TRAPPC2L 
    GenScript Custom Purified and Recombinant Proteins Services for TRAPPC2L
    Novus Biologicals TRAPPC2L Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TRAPPC2L

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005794Golgi apparatus IEA--
    GO:0048471perinuclear region of cytoplasm IEA--

    TRAPPC2L for ontologies           About GeneDecksing



    TRAPPC2L Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TRAPPC2L 
    GenScript Custom Superior Antibodies Services for TRAPPC2L
    Novus Biologicals TRAPPC2L Antibodies
    Abcam antibodies for TRAPPC2L 
    Uscn Antibodies for TRAPPC2L
    Search ThermoFisher Antibodies for TRAPPC2L

    Assay Products for TRAPPC2L: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TRAPPC2L
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TRAPPC2L


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TRAPPC2L for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR006722 Sedlin
     IPR011012 Longin-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9UL33

    ProtoNet protein and cluster: Q9UL33

    1 Blocks protein family: IPB006722 Sedlin

    UniProtKB/Swiss-Prot: TPC2L_HUMAN, Q9UL33
    Similarity: Belongs to the TRAPP small subunits family. Sedlin subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TPC2L_HUMAN, Q9UL33
    Function: May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Animal Models:

       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TRAPPC2L 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: TRAPPC2L
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRAPPC2L
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRAPPC2L
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRAPPC2L (see all 7)
    OriGene shRNA RFP: TRAPPC2L
    OriGene siRNA: TRAPPC2L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAPPC2L
    Sirion Biotech Custom design and validation of potent shRNA sequences against TRAPPC2L 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRAPPC2L
    Sirion Biotech Customized adenovirus for overexpression of TRAPPC2L 
    Sirion Biotech Customized adenovirus for potent knockdown of TRAPPC2L

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TRAPPC2L (NM_016209)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRAPPC2L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC2L 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TRAPPC2L
    Search LifeMap BioReagents cell lines for TRAPPC2L
    Sirion Biotech Customized stable knockdown cell line services for TRAPPC2L 
    Sirion Biotech Customized inducible knockdown cell line services for TRAPPC2L
    Sirion Biotech Customized stable overexpressing cell line services for TRAPPC2L
    Sirion Biotech Customized inducible overexpressing cell line services for TRAPPC2L

    In Situ Assay
    Products:
       

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TRAPPC2L


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRAPPC2L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/11 Interacting proteins for TRAPPC2L (Q9UL332, 3 ENSP000003010214) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LAP3P288382, 3, ENSP000002262994MINT-8201546 I2D: score=1 STRING: ENSP00000226299
    SPATA22Q8NHS92, 3, ENSP000002689814MINT-8201631 I2D: score=1 STRING: ENSP00000268981
    TRAPPC3O436172, 3, ENSP000003622614MINT-8201511 I2D: score=5 STRING: ENSP00000362261
    POSTNQ150632, 3, ENSP000003690714MINT-8201496 I2D: score=1 STRING: ENSP00000369071
    REPS2Q8NFH82, 3, ENSP000003498244MINT-8201570 I2D: score=1 STRING: ENSP00000349824
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006888ER to Golgi vesicle-mediated transport IEA--

    TRAPPC2L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRAPPC2L
    Search CenterWatch for drugs/clinical trials and news about TRAPPC2L / TPC2L 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRAPPC2L gene: 
    NM_016209.3  

    Unigene Cluster for TRAPPC2L:

    Trafficking protein particle complex 2-like
    Hs.461722  [show with all ESTs]
    Unigene Representative Sequence: BC011369
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000564365(uc010cie.3) ENST00000567895 ENST00000301021(uc002fmc.3 uc002fmd.3 uc002fme.3)
    ENST00000564547 ENST00000562792 ENST00000565504 ENST00000565205 ENST00000567312
    ENST00000568583 ENST00000564404 ENST00000561840 ENST00000565309 ENST00000562125
    ENST00000563514

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: TRAPPC2L
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRAPPC2L
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRAPPC2L
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRAPPC2L (see all 7)
    OriGene shRNA RFP: TRAPPC2L
    OriGene siRNA: TRAPPC2L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAPPC2L
    Sirion Biotech Custom design and validation of potent shRNA sequences against TRAPPC2L 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TRAPPC2L (NM_016209)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRAPPC2L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC2L 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRAPPC2L
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRAPPC2L
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC2L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAPPC2L

    Additional cDNA sequence: 

    AF089106.1 AF161524.1 AK307253.1 AK310805.1 AK311885.1 BC011369.1 BC017440.1 BC018024.1 
    BC105809.1 

    17 DOTS entries:

    DT.216290  DT.95274868  DT.91923953  DT.95274869  DT.100773343  DT.95156369  DT.102831574  DT.91750353 
    DT.100806547  DT.120681847  DT.100732623  DT.100763521  DT.100837945  DT.95274875  DT.95274878  DT.100688043 
    DT.91896154 

    24/250 AceView cDNA sequences (see all 250):

    AA741422 BU521936 BM827608 AL559531 AA262106 BU730692 BX419849 CD673247 
    AI185714 BX398570 AI128595 AI423033 AW162472 AW160461 AI419014 CA430946 
    BU844720 AW006672 CD644104 BM709055 D53707 AA383266 CR619389 CA433866 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC2L (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g
    SP1:                    -                 -     -     -     -                             -                                       
    SP2:                    -                 -     -     -     -                             -                                       
    SP3:                    -     -           -     -     -     -                             -                                       
    SP4:                    -     -           -     -     -     -                             -                                       
    SP5:                    -                 -     -     -     -                                                                     


    ECgene alternative splicing isoforms for TRAPPC2L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRAPPC2L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCTCTCAAC
    TRAPPC2L Expression
    About this image
    See TRAPPC2L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRAPPC2L

    SOURCE GeneReport for Unigene cluster: Hs.461722

    UniProtKB/Swiss-Prot: TPC2L_HUMAN, Q9UL33
    Tissue specificity: Expressed in testis, liver, bladder, lung, spleen and brain, several cell lines and primary
    chondrocytes cell line

        SABiosciences Custom PCR Arrays for TRAPPC2L
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRAPPC2L
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRAPPC2L
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC2L
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAPPC2L
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TRAPPC2L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TRAPPC2L gene from 9/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trappc2l1 , 5 trafficking protein particle complex 2-like1, 5 88.97(n)1
    98.56(a)1
      8 (71.92 cM)5
    590051  NM_021502.21  NP_067477.11 
     1226116265 
    chicken
    (Gallus gallus)
    Aves TRAPPC2L1 trafficking protein particle complex 2-like 84.41(n)
    94.96(a)
      415847  XM_414207.3  XP_414207.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAPPC2L6
    --
    94(a)
    1 ↔ 1
    GL343948.1(19087-22546)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480361752   -- 78.19(n)    48036175 
    zebrafish
    (Danio rerio)
    Actinopterygii trappc2l1 trafficking protein particle complex 2-like 78.1(n)
    86.86(a)
      445112  NM_001003506.2  NP_001003506.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90671 CG9067 63.43(n)
    55.22(a)
      36197  NM_136818.1  NP_610662.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T10F2.56
    --
    30(a)
    1 ↔ 1
    III(5158834-5159568)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G209301 sedlin-N conserved region-containing protein 55.39(n)
    48.12(a)
      816627  NM_127662.3  NP_565493.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g05415001 hypothetical protein 54.39(n)
    47.37(a)
      4347731  NM_001070349.1  NP_001063814.2 


    ENSEMBL Gene Tree for TRAPPC2L (if available)
    TreeFam Gene Tree for TRAPPC2L (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRAPPC2L gene

    TRAPPC2L for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TRAPPC2L
    PGOHUM00000262827


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/88 NCBI SNPs in TRAPPC2L are shown (see all 88    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs124476351,2
    C,F,H--88925377(+) AGAGCC/TATTTG 1 -- int11Minor allele frequency- T:0.33NA 6
    rs1910843961,2
    --88925394(+) GCAAGA/GCTAGA 1 -- int10--------
    rs99276841,2
    C,F,A,H--88925455(+) AGGAAG/CTGGGA 1 -- int111Minor allele frequency- C:0.23NS EA WA CSA NA 662
    rs110767281,2
    C,F,A,H--88925567(+) GCCTCG/TTATGT 1 -- int112Minor allele frequency- T:0.50NA WA CSA EA 378
    rs1428275291,2
    --88925592(+) CTAGTC/TCCTTG 1 -- int10--------
    rs1818219911,2
    --88925641(+) CCAAAA/GGTCAT 1 -- int10--------
    rs37848761,2
    C,F,H--88925647(-) TACATG/TATGAC 1 -- int17Minor allele frequency- T:0.02NS EA CSA WA NA 534
    rs1460677341,2
    --88925722(+) GGATCC/TGCCTT 1 -- int10--------
    rs1387884711,2
    --88925816(+) ACTCGA/GAGTCT 1 -- int10--------
    rs37848751,2
    C,F,H--88925897(-) GCGACG/ATCTGG 1 -- int15Minor allele frequency- A:0.01EA NS 1914

    HapMap Linkage Disequilibrium report for TRAPPC2L (88922628 - 88929094 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for TRAPPC2L
         6 CNVs: 59565 30015 59564 4976 30016 4975

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRAPPC2L
    DNA2.0 Custom Variant and Variant Library Synthesis for TRAPPC2L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TRAPPC2L for disorders           About GeneDecksing

    OMIM gene information: 610970    OMIM disorders: --

    1 disease for TRAPPC2L:    About MalaCards
    malaria


    Export disorders for TRAPPC2L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRAPPC2L gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with TRAPPC2L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    2. C4orf41 and TTC-15 are mammalian TRAPP components wit h a role at an early stage in ER-to-Golgi trafficking. (PubMed id 21525244)1, 2 Scrivens P.J....Sacher M. (2011)
    3. TRAPPC2L is a novel, highly conserved TRAPP-interacting protein. (PubMed id 19416478)1, 2 Scrivens P.J.... Sacher M. (2009)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Organization and assembly of the TRAPPII complex. (PubMed id 21453443)1 Choi C....Conibear E. (2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51693 HGNC: 30887 AceView: HSPC176 Ensembl:ENSG00000167515 euGenes: HUgn51693
    ECgene: TRAPPC2L H-InvDB: TRAPPC2L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRAPPC2L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRAPPC2L gene:
    Search GeneIP for patents involving TRAPPC2L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for TRAPPC2L  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRAPPC2L   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRAPPC2L  
     OriGene Protein Over-expression Lysate for TRAPPC2L   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TRAPPC2L   OriGene 3'-UTR Clone for TRAPPC2L  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAPPC2L  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for TRAPPC2L   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TRAPPC2L   OriGene Custom Protein Services for TRAPPC2L  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRAPPC2L
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRAPPC2L
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAPPC2L
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAPPC2L
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAPPC2L
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAPPC2L
     GenScript Custom Purified and Recombinant Proteins Services for TRAPPC2L GenScript cDNA clones with any tag delivered in your preferred vector for TRAPPC2L
     GenScript Custom Assay Services for TRAPPC2L GenScript Custom Superior Antibodies Services for TRAPPC2L
     GenScript Custom overexpressing Cell Line Services for TRAPPC2L CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TRAPPC2L promoter
     Search Chromatin IP Primers for TRAPPC2L
     RT2 qPCR Primer Assay in human, mouse, rat TRAPPC2L
     Search GNC Networks for TRAPPC2L
     SABiosciences Custom PCR Arrays for TRAPPC2L
     Search Tocris compounds for TRAPPC2L
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TRAPPC2L antibodies
     TRAPPC2L lysates
     Antibodies for TRAPPC2L
     See all of Abcam's Antibodies, Kits and Proteins for TRAPPC2L
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TRAPPC2L Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TRAPPC2L
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TRAPPC2L
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TRAPPC2L
     SwitchGear Promoter luciferase reporter plasmids for TRAPPC2L
     Search ThermoFisher Antibodies for TRAPPC2L
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAPPC2L
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TRAPPC2L
    Sirion Biotech Customized:
     stable knockdown cell line services for TRAPPC2L
     inducible knockdown cell line services for TRAPPC2L
     design and validation of potent shRNA sequences against TRAPPC2L
     adenovirus for potent knockdown of TRAPPC2L
     adenovirus for overexpression of TRAPPC2L
     stable overexpressing cell line services for TRAPPC2L
     inducible overexpressing cell line services for TRAPPC2L
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TRAPPC2L gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4