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Aliases for TRAPPC13 Gene

Aliases for TRAPPC13 Gene

  • Trafficking Protein Particle Complex 13 2 3 5
  • Trs65-Related 2 3
  • C5orf44 3 4
  • Trafficking Protein Particle Complex Subunit 13 3
  • Chromosome 5 Open Reading Frame 44 2
  • UPF0533 Protein C5orf44 3

External Ids for TRAPPC13 Gene

Previous HGNC Symbols for TRAPPC13 Gene

  • C5orf44

Previous GeneCards Identifiers for TRAPPC13 Gene

  • GC05P064923
  • GC05P064925

Summaries for TRAPPC13 Gene

GeneCards Summary for TRAPPC13 Gene

TRAPPC13 (Trafficking Protein Particle Complex 13) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAPPC13 Gene

Genomics for TRAPPC13 Gene

Regulatory Elements for TRAPPC13 Gene

Enhancers for TRAPPC13 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F065478 1.4 FANTOM5 ENCODE 9.1 -143.4 -143380 5.4 PKNOX1 SIN3A FEZF1 DMAP1 ZNF2 YY1 FOS ZNF263 SP3 MXD4 PPWD1 CENPK TRAPPC13 ENSG00000250081 ADAMTS6 RPS2P23
GH05F065623 1.1 ENCODE 9.6 +0.1 98 3.2 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 CBX5 PPWD1 CENPK RNU6-540P NLN SGTB ENSG00000272354 TRAPPC13 ENSG00000253251 TRIM23
GH05F065562 1.1 ENCODE 9 -61.3 -61292 2.8 PKNOX1 ARNT WRNIP1 ARID4B SIN3A ZNF2 YY1 SLC30A9 ZNF143 ZNF207 PPWD1 CENPK RNU6-540P TRAPPC13 GC05M065605
GH05F065821 1.2 Ensembl ENCODE 6.8 +199.7 199720 5.2 PKNOX1 ATF1 ZNF766 JUNB TBX21 SMARCA4 GLIS1 NBN KDM1A WT1 TRAPPC13 ERBIN NLN GC05P065768 ENSG00000269961
GH05F065196 1.5 FANTOM5 Ensembl ENCODE 4.8 -420.7 -420699 14.4 SIN3A RAD21 RFX5 ZNF335 GLIS2 ZNF366 RCOR1 FOS EGR2 ZBTB11 TRAPPC13 CENPK ADAMTS6 LOC100419140 ENSG00000207439
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRAPPC13 on UCSC Golden Path with GeneCards custom track

Promoters for TRAPPC13 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for TRAPPC13 Gene

65,624,716 bp from pter
65,666,233 bp from pter
41,518 bases
Plus strand

Genomic View for TRAPPC13 Gene

Genes around TRAPPC13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAPPC13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAPPC13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAPPC13 Gene

Proteins for TRAPPC13 Gene

  • Protein details for TRAPPC13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Trafficking protein particle complex subunit 13
    Protein Accession:
    Secondary Accessions:
    • Q17RZ9
    • Q49A23
    • Q4JHG0
    • Q6MZG4
    • Q8TCM2
    • Q9H8I3

    Protein attributes for TRAPPC13 Gene

    417 amino acids
    Molecular mass:
    46524 Da
    Quaternary structure:
    • Part of the multisubunit TRAPP (transport protein particle) complex.
    • Sequence=AAH47475.1; Type=Miscellaneous discrepancy; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAB14633.1; Type=Erroneous termination; Positions=63; Note=Translated as Glu.; Evidence={ECO:0000305};

    Alternative splice isoforms for TRAPPC13 Gene


neXtProt entry for TRAPPC13 Gene

Post-translational modifications for TRAPPC13 Gene

  • Ubiquitination at Lys 165 and Lys 264
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TRAPPC13 Gene

Domains & Families for TRAPPC13 Gene

Gene Families for TRAPPC13 Gene

Protein Domains for TRAPPC13 Gene


Suggested Antigen Peptide Sequences for TRAPPC13 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TRAPPC13 family.
  • Belongs to the TRAPPC13 family.
genes like me logo Genes that share domains with TRAPPC13: view

Function for TRAPPC13 Gene

Gene Ontology (GO) - Molecular Function for TRAPPC13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 21453443
genes like me logo Genes that share ontologies with TRAPPC13: view
genes like me logo Genes that share phenotypes with TRAPPC13: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRAPPC13 Gene

Localization for TRAPPC13 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRAPPC13 gene
Compartment Confidence
cytosol 5
plasma membrane 2
nucleus 2
mitochondrion 1
endoplasmic reticulum 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TRAPPC13 Gene

Pathways & Interactions for TRAPPC13 Gene

genes like me logo Genes that share pathways with TRAPPC13: view

Pathways by source for TRAPPC13 Gene

2 Reactome pathways for TRAPPC13 Gene

Gene Ontology (GO) - Biological Process for TRAPPC13 Gene


No data available for SIGNOR curated interactions for TRAPPC13 Gene

Transcripts for TRAPPC13 Gene

Unigene Clusters for TRAPPC13 Gene

Trafficking protein particle complex 13:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAPPC13 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b · 13c · 13d ^ 14a · 14b ·
SP1: - - -
SP2: - - -
SP3: - - -
SP4: - - -
SP5: - - -
SP6: -
SP7: -

ExUns: 14c · 14d

Relevant External Links for TRAPPC13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRAPPC13 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRAPPC13 Gene

Protein differential expression in normal tissues from HIPED for TRAPPC13 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (28.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TRAPPC13 Gene

Protein tissue co-expression partners for TRAPPC13 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TRAPPC13 Gene:


SOURCE GeneReport for Unigene cluster for TRAPPC13 Gene:

genes like me logo Genes that share expression patterns with TRAPPC13: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRAPPC13 Gene

Orthologs for TRAPPC13 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TRAPPC13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TRAPPC13 34
  • 99.6 (n)
C5ORF44 35
  • 99 (a)
(Monodelphis domestica)
Mammalia TRAPPC13 35
  • 94 (a)
(Bos Taurus)
Mammalia TRAPPC13 34 35
  • 93.76 (n)
(Canis familiaris)
Mammalia TRAPPC13 34 35
  • 93.54 (n)
(Rattus norvegicus)
Mammalia Trappc13 34
  • 89.31 (n)
(Mus musculus)
Mammalia Trappc13 34 16 35
  • 89 (n)
(Ornithorhynchus anatinus)
Mammalia TRAPPC13 35
  • 77 (a)
(Gallus gallus)
Aves CZH5ORF44 34 35
  • 82.78 (n)
(Anolis carolinensis)
Reptilia TRAPPC13 35
  • 92 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia trappc13 34
  • 77.18 (n)
Str.3852 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.2220 34
(Danio rerio)
Actinopterygii trappc13 34 35
  • 72.82 (n)
sbcb318 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005561 34
  • 53.55 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG4953 34 35
  • 50.34 (n)
(Caenorhabditis elegans)
Secernentea C56C10.7 34 35
  • 55.38 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G47960 34
  • 47.81 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 51 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU01664 34
Species where no ortholog for TRAPPC13 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRAPPC13 Gene

Gene Tree for TRAPPC13 (if available)
Gene Tree for TRAPPC13 (if available)

Paralogs for TRAPPC13 Gene

(1) SIMAP similar genes for TRAPPC13 Gene using alignment to 4 proteins: Pseudogenes for TRAPPC13 Gene

genes like me logo Genes that share paralogs with TRAPPC13: view

No data available for Paralogs for TRAPPC13 Gene

Variants for TRAPPC13 Gene

Sequence variations from dbSNP and Humsavar for TRAPPC13 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10039789 -- 65,655,944(+) TGTCA(A/C)ATGGC intron-variant
rs10040083 -- 65,643,964(+) atatt(A/C)tctga intron-variant
rs10057241 -- 65,640,477(+) TCCAG(C/T)TACCA intron-variant
rs10071395 -- 65,624,735(+) ttttt(A/T)AAAAA nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs10074627 -- 65,638,435(+) GAATG(A/C)GAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRAPPC13 Gene

Variant ID Type Subtype PubMed ID
esv3425811 CNV insertion 20981092
esv3894204 CNV loss 25118596

Variation tolerance for TRAPPC13 Gene

Residual Variation Intolerance Score: 46.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.77; 33.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRAPPC13 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRAPPC13 Gene

Disorders for TRAPPC13 Gene

Relevant External Links for TRAPPC13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRAPPC13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRAPPC13 Gene

Publications for TRAPPC13 Gene

  1. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. (PMID: 23394947) Bassik M.C. … Weissman J.S. (Cell 2013) 2 3 64
  2. Organization and assembly of the TRAPPII complex. (PMID: 21453443) Choi C. … Conibear E. (Traffic 2011) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 64

Products for TRAPPC13 Gene

Sources for TRAPPC13 Gene

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