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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRAM1 Gene

protein-coding   GIFtS: 60
GCID: GC08M071535

Translocation Associated Membrane Protein 1

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Translocation Associated Membrane Protein 11 2     Translocating Chain-Associated Membrane Protein 12
TRAM2 3 5     Translocating Chain-Associating Membrane Protein2
PNAS82     Translocation-Associating Membrane Protein 12
TRAMP2     

External Ids:    HGNC: 205681   Entrez Gene: 234712   Ensembl: ENSG000000671677   OMIM: 6051905   UniProtKB: Q156293   

Export aliases for TRAM1 gene to outside databases

Previous GC identifers: GC08M071426 GC08M071208 GC08M071648 GC08M066978


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRAM1 Gene:
This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded
protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic
reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during
a translocational pause. (provided by RefSeq, Oct 2009)

GeneCards Summary for TRAM1 Gene: 
TRAM1 (translocation associated membrane protein 1) is a protein-coding gene. Diseases associated with TRAM1 include dengue hemorrhagic fever, and hemorrhagic fever, and among its related super-pathways are Viral mRNA Translation and Generic Transcription Pathway. GO annotations related to this gene include protein binding and receptor activity. An important paralog of this gene is TRAM1L1.

UniProtKB/Swiss-Prot: TRAM1_HUMAN, Q15629
Function: Stimulatory or required for the translocation of secretory proteins across the ER membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NT_008183.19  NC_018919.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRAM1 gene promoter:
         HOXA9   HOXA9B   AREB6   S8   HOXA3   FOXO4   Lmo2   Pax-4a   Meis-1   Meis-1b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAM1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRAM1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q13.3   Ensembl cytogenetic band:  8q13.3   HGNC cytogenetic band: 8q13.1

TRAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAM1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M071535:  view genomic region     (about GC identifiers)

Start:
71,485,453 bp from pter      End:
71,520,694 bp from pter
Size:
35,242 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRAM1_HUMAN, Q15629 (See protein sequence)
Recommended Name: Translocating chain-associated membrane protein 1  
Size: 374 amino acids; 43072 Da
Subunit: Interacts with human cytomegalovirus/HHV-5 protein US2
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Explore the universe of human proteins at neXtProt for TRAM1: NX_Q15629

Explore proteomics data for TRAM1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q15629

  • TRAM1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRAM1 Protein Expression
    REFSEQ proteins: NP_055109.1  
    ENSEMBL proteins: 
     ENSP00000428052   ENSP00000262213   ENSP00000428025   ENSP00000439359  
    Reactome Protein details: Q15629
    Human Recombinant Protein Products for TRAM1: 
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    Novus Biologicals TRAM1 Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRAM1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum TAS1315422
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--

    TRAM1 for ontologies           About GeneDecksing



    TRAM1 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for TRAM1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR016447 Translocation_assoc_membrane
     IPR013599 TRAM1
     IPR006634 TLC-dom

    Graphical View of Domain Structure for InterPro Entry Q15629

    ProtoNet protein and cluster: Q15629

    3 Blocks protein domains:
    IPB005547 Longevity-assurance protein (LAG1)
    IPB006634 TRAM
    IPB013599 TRAM1-like protein


    UniProtKB/Swiss-Prot: TRAM1_HUMAN, Q15629
    Similarity: Belongs to the TRAM family
    Similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain


    TRAM1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRAM1_HUMAN, Q15629
    Function: Stimulatory or required for the translocation of secretory proteins across the ER membrane

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity TAS1315422
    GO:0005515protein binding IPI18555783
         
    TRAM1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TRAM1:
     Decreased influenza A/WSN/33 r 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRAM1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRAM1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRAM1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRAM1 

    miRNA
    Products:
        
    miRTarBase miRNAs that target TRAM1:
    hsa-mir-155 (MIRT001493)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRAM1
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate TRAM1 (see all 15):
    hsa-miR-4307 hsa-miR-187* hsa-miR-15a hsa-miR-218-1* hsa-miR-548v hsa-miR-497 hsa-miR-181a-2* hsa-miR-551b*
    SwitchGear 3'UTR luciferase reporter plasmidTRAM1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRAM1
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAM1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TRAM1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral mRNA Translation
    Translation0.78
    SRP-dependent cotranslational protein targeting to membrane0.77
    2Generic Transcription Pathway
    Gene Expression0.47
    3Asparagine N-linked glycosylation
    Metabolism of proteins0.35
    4Protein processing in endoplasmic reticulum
    Protein processing in endoplasmic reticulum

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for TRAM1
        Translation
    SRP-dependent cotranslational protein targeting to membrane
    Metabolism of proteins
    Gene Expression


    1         Kegg Pathway  (Kegg details for TRAM1):
        Protein processing in endoplasmic reticulum


    TRAM1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRAM1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/98 Interacting proteins for TRAM1 (Q156291, 3 ENSP000002622134) via UniProtKB, MINT, STRING, and/or I2D (see all 98)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL9P329693, ENSP000003460224I2D: score=5 STRING: ENSP00000346022
    RPL9P7P329693I2D: score=5 
    RPL9P8P329693I2D: score=5 
    RPL9P9P329693I2D: score=5 
    BCAP31P515721, 3, ENSP000003923304EBI-1788852,EBI-77683 I2D: score=1 STRING: ENSP00000392330
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006412translation TAS--
    GO:0006613cotranslational protein targeting to membrane TAS1315422
    GO:0006614SRP-dependent cotranslational protein targeting to membrane TAS--
    GO:0010467gene expression TAS--
    GO:0019048modulation by virus of host morphology or physiology IEA--

    TRAM1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRAM1

    Search CenterWatch for drugs/clinical trials and news about TRAM1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRAM1 gene: 
    NM_014294.5  

    Unigene Cluster for TRAM1:

    Translocation associated membrane protein 1
    Hs.491988  [show with all ESTs]
    Unigene Representative Sequence: BC032018
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000521425 ENST00000262213(uc011lfc.2 uc003xyo.2) ENST00000521049
    ENST00000520700 ENST00000518678 ENST00000536748
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRAM1
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate TRAM1 (see all 15):
    hsa-miR-4307 hsa-miR-187* hsa-miR-15a hsa-miR-218-1* hsa-miR-548v hsa-miR-497 hsa-miR-181a-2* hsa-miR-551b*
    SwitchGear 3'UTR luciferase reporter plasmidTRAM1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAM1
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRAM1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAM1
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    Primer
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    OriGene qPCR primer pairs and template standards for TRAM1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAM1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAM1

    Additional mRNA sequence: 

    AF130055.2 AF274933.1 AK289397.1 AK292777.1 AK303411.1 BC000687.2 BC020283.1 BC032018.1 
    BC037738.1 BT007359.1 CR541654.1 CR541739.1 X63679.1 

    13 DOTS entries:

    DT.218609  DT.95141399  DT.100846268  DT.101984582  DT.121470766  DT.92450963  DT.87046040  DT.100846269 
    DT.40106518  DT.85104271  DT.40291068  DT.91950057  DT.99985880 

    24/488 AceView cDNA sequences (see all 488):

    BI492372 BQ022521 BF366638 AA375865 AI201635 CR601735 AW276270 BP340204 
    BF969571 CB853722 AW510577 CN483237 BQ233660 BU152628 BC000687 BM754140 
    AI991359 CB150436 BM758920 BF901474 AW470653 AI827296 BU146257 BM799776 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TRAM1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:              -                                                                     
    SP2:                                                                                    
    SP3:              -                                                                     
    SP4:              -           -                                                         


    ECgene alternative splicing isoforms for TRAM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRAM1 expression in normal human tissues (normalized intensities)      TRAM1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCTAGGAA
    TRAM1 Expression
    About this image


    TRAM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Thymus (Hematopoietic System)
             Double Negative 2 Thymocytes Thymus
     
     Blood (Cardiovascular System)
             Double Negative 2 Thymocytes Thymus

    See TRAM1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRAM1

    SOURCE GeneReport for Unigene cluster: Hs.491988
        SABiosciences Custom PCR Arrays for TRAM1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TRAM1 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tram11 , 5 translocating chain-associating membrane protein 11, 5 87.34(n)1
    93.05(a)1
      1 (4.18 cM)5
    722651  NM_028173.41  NP_082449.11 
     135647025 
    chicken
    (Gallus gallus)
    Aves TRAM11 translocation associated membrane protein 1 80.57(n)
    83.69(a)
      378918  NM_204400.2  NP_989731.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    --
    85(a)
    65(a)
    1 ↔ many
    possible ortholog
    4(32375467-32408969)
    4(145154466-145172122)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.205452 Xenopus laevis transcribed sequence with moderate similarity more 77.16(n)    BU914571.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tram2 translocating chain-associating membrane protein 76.43(n)   266757  BC063238.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta TRAM1 CG11642-PA 49.3(n)
    43.98(a)
      31042  NM_166866.1  NP_726710.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tram-11 Protein TRAM-1 50.6(n)
    40.72(a)
      177902  NM_069468.2  NP_501869.1 


    ENSEMBL Gene Tree for TRAM1 (if available)
    TreeFam Gene Tree for TRAM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRAM1 gene
    TRAM1L12  TRAM22  
    2 SIMAP similar genes for TRAM1 using alignment to 6 protein entries:     TRAM1_HUMAN (see all proteins):
    TRAM1L1    TRAM2

    TRAM1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/704 SNPs in TRAM1 are shown (see all 704)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1147458461,2
    C,F--71484993(+) CAGAGT/GAGCAA 1 -- ds50011Minor allele frequency- G:0.04WA 118
    rs1497048091,2
    --71485000(+) GCAAAA/GCAACT 1 -- ds50010--------
    rs1887180561,2
    --71485004(+) AGCAAC/TTAATT 1 -- ds50010--------
    rs1444835021,2
    --71485078(+) TCCCAC/TCATGC 1 -- ds50010--------
    rs1932944711,2
    C--71485245(+) TGGTAA/GTGACA 1 -- ds50010--------
    rs348976181,2
    C--71485260(+) TTTTTT/-CTTTG 1 -- ds50012Minor allele frequency- -:0.25NA CSA 4
    rs2007309511,2
    C--71485271(-) GCAAAA/GAAAAA 1 -- ds50010--------
    rs20351961,2
    C,F,H--71485350(+) AAATAA/CGGTGG 1 -- ds500127Minor allele frequency- C:0.20NS EA NA MN WA 2886
    rs1847164421,2
    --71485449(+) ACCTTG/TAGGTT 1 -- ds50010--------
    rs785768481,2
    C,F--71485482(+) ATTTAT/CTTGGT 1 -- ut311Minor allele frequency- C:0.01WA 118

    HapMap Linkage Disequilibrium report for TRAM1 (71485453 - 71520694 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRAM1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv7805n71CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605190    OMIM disorders: --

    7 diseases for TRAM1:    About MalaCards
    dengue hemorrhagic fever    hemorrhagic fever    peritonitis    meningioma
    hepatitis c    hepatitis    leukemia


    TRAM1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRAM1
    Human Genome Epidemiology (HuGE) Navigator: TRAM1 (6 documents)

    Export disorders for TRAM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRAM1 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with TRAM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A protein of the endoplasmic reticulum involved early in polypeptide translocation. (PubMed id 1315422)1, 2, 3 Goerlich D.... Rapoport T.A. (1992)
    2. TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein. (PubMed id 19121997)1, 2, 9 Oresic K....Tortorella D. (2009)
    3. Dengue hemorrhagic fever is associated with polymorph isms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (2010)
    4. Risk of meningioma and common variation in genes rela ted to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (2010)
    5. Polymorphisms in innate immunity genes and risk of ch ildhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (2010)
    6. Large-scale candidate gene analysis of spontaneous cl earance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (2010)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Association of genome-wide variation with highly sensi tive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies. (PubMed id 23247143)1 Yu B....Boerwinkle E. (2013)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23471 HGNC: 20568 AceView: TRAM1 Ensembl:ENSG00000067167 euGenes: HUgn23471
    ECgene: TRAM1 Kegg: 23471 H-InvDB: TRAM1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRAM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TRAM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRAM1 gene:
    Search GeneIP for patents involving TRAM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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