TRAK1 Gene
protein-coding GIFtS: 52
GCID: GC03P042108
|
|
trafficking protein, kinesin binding 1
| |
Aliases
for TRAK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Trafficking Protein, Kinesin Binding 11 2 | | Milton Homolog 12 | | OIP1061 2 3 5 | | O-Linked N-Acetylglucosamine Transferase Interacting Protein 1062 | | KIAA10421 3 5 | | OGT(O-Glc-NAc Transferase)-Interacting Protein 106 KDa2 | | MILT11 2 | | Trafficking Kinesin-Binding Protein 12 | | 106 KDa O-GlcNAc Transferase-Interacting Protein2 3 | | |
Export aliases for TRAK1 gene to outside databases |
Summaries
for TRAK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: TRAK1_HUMAN, Q9UPV9Function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFRcomplexes and GABA-A receptors
Gene Wiki entry for TRAK1
|
Genomic Views
for TRAK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TRAK1 gene promoter:
USF1 AML1a ATF-2 Nkx2-5 CUTL1 LCR-F1 E2F-1 E2F USF-1 Chx10
Other transcription factors
Search SABiosciences Chromatin IP Primers for TRAK1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAK1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p22.1 Ensembl cytogenetic band: 3p22.1 HGNC cytogenetic band: 3p22.1TRAK1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P042108: view genomic region
(about GC identifiers)
Start:
|
42,055,294 bp from pter |
End:
|
42,267,381 bp from pter |
Size:
|
212,088 bases |
Orientation:
|
plus strand |
|
Proteins
for TRAK1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRAK1_HUMAN, Q9UPV9 (See
protein sequence)Recommended Name: Trafficking kinesin-binding protein 1 Size: 953 amino acids; 106040 Da
Subunit: Interacts with O-GlcNAc transferase. Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Interacts with HGS.Interacts with GABRA1 (By similarity). Interacts with KIF5C
Subcellular location: Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Note=Predominantly associated withearly endosome. The localization to early endosomes depends on its interaction with HRS. Colocalizes with MGARP at themitochondria
Miscellaneous: Over-expressed in all investigated carcinomas, especially in gastric adenocarcinoma and signet-ringcarcinoma and may serve as a marker of gastric cancer
Sequence caution: Sequence=BAA82994.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: E9PDS2 Q63HR0 Q659B5 Q96B69Alternative splicing: 3 isoforms: Q9UPV9-1 Q9UPV9-2 Q9UPV9-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TRAK1: NX_Q9UPV9
Post-translational modifications:
O-glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPV9
TRAK1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001036111.1 NP_001252537.1 NP_001252538.1 NP_001252539.1 NP_055780.2
ENSEMBL proteins: ENSP00000328998 ENSP00000410717 ENSP00000409940 ENSP00000379478 ENSP00000340702 ENSP00000413729
Human Recombinant Protein Products for TRAK1:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
TRAK1 for ontologies About GeneDecksing
TRAK1 Antibody Products:
Assay Products for TRAK1: |
Protein
Domains /
Families
for TRAK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TRAK1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UPV9ProtoNet protein and cluster: Q9UPV9 1 Blocks protein family: IPB006933 HAP1
UniProtKB/Swiss-Prot: TRAK1_HUMAN, Q9UPV9Domain: The C-terminal region is required for the early endosomal and mitochondrial localizationSimilarity: Contains 1 HAP1 N-terminal domain |
Function
for TRAK1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TRAK1_HUMAN, Q9UPV9Function: Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFRcomplexes and GABA-A receptors Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
TRAK1 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for TRAK1:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Trak1):
TRAK1 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TRAK1 (NM_001042646) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRAK1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAK1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAK1 |
|
Pathways & Interactions
for TRAK1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRAK1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/13 Interacting proteins for TRAK1 (Q9UPV91, 2, 3 ENSP000003289984) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
ISS | -- | | GO:0006493 | protein O-linked glycosylation |
ISS | -- | | GO:0006605 | protein targeting |
ISS | -- | | GO:0008333 | endosome to lysosome transport |
IDA | 18675823 |
TRAK1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TRAK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TRAK1
Search CenterWatch for drugs/clinical trials and news about TRAK1
|
Transcripts
for TRAK1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TRAK1 gene (5 alternative transcripts): NM_001042646.2 NM_001265608.1 NM_001265609.1 NM_001265610.1 NM_014965.4 Unigene Cluster for TRAK1: Trafficking protein, kinesin binding 1 Hs.535711 [show with all ESTs]Unigene Representative Sequence: NM_0010426469 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000487159 ENST00000484786 ENST00000327628(uc003cky.3 uc011azi.2)
ENST00000449246(uc003ckz.4) ENST00000418790 ENST00000396175 ENST00000341421(uc011azh.2 uc011azj.2 uc003cla.3)
ENST00000469506 ENST00000427771
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TRAK1 (NM_001042646) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRAK1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAK1 |
Additional cDNA sequence: AB028965.1 AK000754.1 AK023962.1 AK294221.1 AK295480.1 AK295848.1 AK316260.1 AL713787.1 BC015922.1 BX647199.1 15 DOTS entries: DT.91704675 DT.118205 DT.100845141 DT.97857649 DT.120869149 DT.99927056 DT.100819026 DT.100819025 DT.120869198 DT.120869252 DT.423174 DT.91938881 DT.97811284 DT.40286676 DT.97816383 24/336 AceView cDNA sequences (see all 336): T16631 AA843369 BQ672189 BG258268 AA037342 AI080032 BQ221547 AA313243 AA359049 BF434023 AI474321 BX499783 AW629968 AI879670 BM922991 Z41254 T28064 AW470772 CR594881 CD245407 BM664005 AA322692 BQ214886 BG285410
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for TRAK1 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | ^ | 17a | · | 17b | · |
|---|
|
| SP1: | | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | |
| ExUns: | 17c | ^ | 18a | · | 18b | ^ | 19a | · | 19b |
|---|
|
| SP1: | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | - | | | | | | | | | |
ECgene alternative splicing isoforms for TRAK1
|
Expression
for TRAK1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TRAK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TRAK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TRAK1
SOURCE GeneReport for Unigene cluster: Hs.535711
UniProtKB/Swiss-Prot: TRAK1_HUMAN, Q9UPV9Tissue specificity: High expression in spinal cord and moderate expression in all other tissues and specific brainregions examined. Expressed in all cell lines examined
SABiosciences Custom PCR Arrays for TRAK1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRAK1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRAK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAK1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAK1 |
Orthologs
for TRAK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TRAK1 gene from 7/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Trak11 , 5 |
trafficking protein, kinesin binding 11, 5 |
88.45(n)1
94.99(a)1 |
|
9 (72.41 cM)5
670951 NM_175114.31 NP_780323.21
1213669585 |
chicken
(Gallus gallus) |
Aves |
TRAK11 |
trafficking protein, kinesin binding 1 |
80.2(n)
89.9(a) |
|
420714 XM_418813.2 XP_418813.2 |
lizard
(Anolis carolinensis) |
Reptilia |
TRAK16 |
-- |
77(a) |
1 ↔ 1 |
GL343224.1(1312802-1365502) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.39422 |
Xenopus laevis transcribed sequence with moderate similarity to protein spQ9UPV9 (H.sapiens) YA42_HUMAN Hypothetical protein KIAA1042 less |
76.28(n) |
|
CB206980.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.261602 |
Transcribed sequence with strong similarity to protein spQ9UPV9 (H.sapiens) YA42_HUMAN Hypothetical protein KIAA1042 less |
92.71(n) |
|
CD581348.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
milt1 |
milton |
47.41(n)
37.39(a) |
|
45683 NM_080765.3 NP_542943.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
T27A3.16 |
Protein T27A3.1, isoform a |
21(a) |
possible ortholog |
I(6122592-6126856) |
ENSEMBL Gene Tree for TRAK1 (if available)
TreeFam Gene Tree for TRAK1 (if available) |
Paralogs
for TRAK1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TRAK1 gene
- TRAK22 HAP12
3 SIMAP similar genes for TRAK1 using alignment to 5 protein entries: TRAK1_HUMAN (see all proteins):DKFZp451C1616 ALS2CR3 TRAK2
TRAK1 for paralogs About GeneDecksing
|
Genomic Variants
for TRAK1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TRAK1 (42055294 - 42267381 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TRAK1
1 CNV: 7410 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRAK1 |
|
Disorders
/ Diseases
for TRAK1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TRAK1 for disorders About GeneDecksing
OMIM gene information: 608112
OMIM disorders: --
12  diseases for TRAK1: About MalaCardshypertonia cerebral palsy gastric adenocarcinoma cerebritis
gastric cancer pharyngitis colorectal cancer adenocarcinoma
schizophrenia neuronitis carcinoma hypoxia
Human Genome Epidemiology (HuGE) Navigator: TRAK1 (1 document)
Export disorders for TRAK1 gene to outside databases
|
Publications
for TRAK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TRAK1 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with TRAK1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase. (PubMed id 12435728)1, 2, 3, 9 Iyer S.P.N.... Hart G.W. (2003)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2, 3 Kikuno R....Ohara O. (1999)
- GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. (PubMed id 15644324)1, 2, 9 Brickley K....Stephenson F.A. (2005)
- The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking. (PubMed id 16630562)1, 2, 9 Fransson S.... Aspenstroem P. (2006)
- Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networks. (PubMed id 20230862)1, 3 Koutsopoulos O.S....Ryan M.T. (2010)
- Identification of TRAK1 (Trafficking protein, kinesin-binding 1) as MGb2-Ag: a novel cancer biomarker. (PubMed id 18986759)1, 2 Zhang F....Fan D. (2009)
- HUMMR, a hypoxia- and HIF-1alpha-inducible protein, a lters mitochondrial distribution and transport. (PubMed id 19528298)1, 2 Li Y....Rempe D.A. (2009)
- Hypertonia-associated protein Trak1 is a novel regulator of endosome-to-lysosome trafficking. (PubMed id 18675823)1, 2 Webber E....Chin L.S. (2008)
- Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. (PubMed id 16380713)1, 3 Gilbert S.L....Lahn B.T. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for TRAK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TRAK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TRAK1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TRAK1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TRAK1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TRAK1 gene:
Search GeneIP for patents involving TRAK1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TRAK1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for TRAK1 | | OriGene shRNA RFP for TRAK1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRAK1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRAK1 | | | OriGene Protein Over-expression Lysate for TRAK1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TRAK1 | | OriGene 3'-UTR Clone for TRAK1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRAK1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TRAK1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TRAK1 | | OriGene Custom Protein Services for TRAK1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRAK1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRAK1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAK1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAK1 |
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| | | | Search Tocris compounds for TRAK1 |
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 | | | TRAK1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAK1 |
|  |  |  |  | | | | ThermoFisher Antibodies for TRAK1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAK1 |
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