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Aliases for TRAJ7 Gene

Aliases for TRAJ7 Gene

  • T-Cell Receptor Alpha Joining 7 2 5
  • T Cell Receptor Alpha Joining 7 2 3

External Ids for TRAJ7 Gene

Previous GeneCards Identifiers for TRAJ7 Gene

  • GC14U990384
  • GC14P020996
  • GC14P022078
  • GC14P023062
  • GC14P023126
  • GC14P023188
  • GC14P023239
  • GC14P023301
  • GC14P023379
  • GC14P023450
  • GC14P023534
  • GC14P023625
  • GC14P023768
  • GC14P022558
  • GC14P022661
  • GC14P022746
  • GC14P022811
  • GC14P023808
  • GC14P023902

Summaries for TRAJ7 Gene

Entrez Gene Summary for TRAJ7 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ7 Gene

TRAJ7 (T-Cell Receptor Alpha Joining 7) is a Protein Coding gene.

Additional gene information for TRAJ7 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ7 Gene

Genomics for TRAJ7 Gene

Regulatory Elements for TRAJ7 Gene

Enhancers for TRAJ7 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H022504 2.1 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +0.6 566 66 HDGF PKNOX1 FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC NGDN OR6J1 MRPL52 SLC7A7
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRAJ7 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAJ7 Gene

Chromosome:
14
Start:
22,537,622 bp from pter
End:
22,537,680 bp from pter
Size:
59 bases
Orientation:
Plus strand

Genomic View for TRAJ7 Gene

Genes around TRAJ7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ7 Gene

Proteins for TRAJ7 Gene

  • Protein details for TRAJ7 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B714
    Recommended name:
    T-cell receptor alpha joining 7
    Protein Accession:
    A0A075B714

    Protein attributes for TRAJ7 Gene

    Size:
    20 amino acids
    Molecular mass:
    2173 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ7 Gene

Post-translational modifications for TRAJ7 Gene

No Post-translational modifications

Other Protein References for TRAJ7 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ7 Gene

Domains & Families for TRAJ7 Gene

Gene Families for TRAJ7 Gene

Protein Domains for TRAJ7 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ7: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ7 Gene

Function for TRAJ7 Gene

Phenotypes From GWAS Catalog for TRAJ7 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRAJ7
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ7 Gene

Localization for TRAJ7 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ7 Gene

Pathways & Interactions for TRAJ7 Gene

SuperPathways for TRAJ7 Gene

No Data Available

Interacting Proteins for TRAJ7 Gene

Gene Ontology (GO) - Biological Process for TRAJ7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ7 Gene

Drugs & Compounds for TRAJ7 Gene

No Compound Related Data Available

Transcripts for TRAJ7 Gene

mRNA/cDNA for TRAJ7 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRAJ7
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ7 Gene

No ASD Table

Relevant External Links for TRAJ7 Gene

GeneLoc Exon Structure for
TRAJ7
ECgene alternative splicing isoforms for
TRAJ7

Expression for TRAJ7 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ7 Gene:

TRAJ7
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ7 Gene

Orthologs for TRAJ7 Gene

Evolution for TRAJ7 Gene

ENSEMBL:
Gene Tree for TRAJ7 (if available)
TreeFam:
Gene Tree for TRAJ7 (if available)

No data available for Orthologs for TRAJ7 Gene

Paralogs for TRAJ7 Gene

No data available for Paralogs for TRAJ7 Gene

Variants for TRAJ7 Gene

Relevant External Links for TRAJ7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ7 Gene

Disorders for TRAJ7 Gene

No disorders were found for TRAJ7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ7 Gene

Publications for TRAJ7 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 60

Products for TRAJ7 Gene

Sources for TRAJ7 Gene

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