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Aliases for TRAJ61 Gene

Aliases for TRAJ61 Gene

  • T Cell Receptor Alpha Joining 61 (Non-Functional) 2 3
  • T-Cell Receptor Alpha Joining 61 (Non-Functional) 5

External Ids for TRAJ61 Gene

Previous GeneCards Identifiers for TRAJ61 Gene

  • GC14U990330
  • GC14P020934
  • GC14P022014
  • GC14P022953
  • GC14P023073
  • GC14P023135
  • GC14P023245
  • GC14P023308
  • GC14P023348
  • GC14P023421
  • GC14P023479
  • GC14P023566
  • GC14P023707
  • GC14P022479
  • GC14P023950

Summaries for TRAJ61 Gene

Entrez Gene Summary for TRAJ61 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ61 Gene

TRAJ61 (T Cell Receptor Alpha Joining 61 (Non-Functional)) is a Protein Coding gene.

Additional gene information for TRAJ61 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ61 Gene

Genomics for TRAJ61 Gene

GeneHancer (GH) Regulatory Elements for TRAJ61 Gene

Promoters and enhancers for TRAJ61 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I022471 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.8 -3.5 -3515 0.4 HDGF NFIB BMI1 ZBTB40 RAD21 RFX5 ELK1 ZNF143 ZNF207 BCLAF1 TRAJ61 TRDV3 ENSG00000251002 LOC105370401 TRA
GH14I022472 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +13.2 13232 32 HDGF PKNOX1 SMAD1 YBX1 IRF4 TCF12 ZNF207 ZNF143 ATF7 RUNX3 GC14P024192 GC14P024203 TRAJ48 TRAJ49 TRAJ50 TRAJ51 PRMT5-AS1 ABHD4 MMP14 MRPL52
GH14I022468 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.4 -5.5 -5547 2.6 MITF MEIS2 ZNF282 PKNOX1 USF1 REST TRDV3 ABHD4 TRAJ61 ENSG00000251002 LOC105370401 TRA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRAJ61 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRAJ61 Gene

Genomic Locations for TRAJ61 Gene
chr14:22,475,316-22,475,375
(GRCh38/hg38)
Size:
60 bases
Orientation:
Plus strand
chr14:22,944,306-22,944,365
(GRCh37/hg19)

Genomic View for TRAJ61 Gene

Genes around TRAJ61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ61 Gene

Proteins for TRAJ61 Gene

  • Protein details for TRAJ61 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B708
    Recommended name:
    T-cell receptor alpha joining 61 (non-functional)
    Protein Accession:
    A0A075B708

    Protein attributes for TRAJ61 Gene

    Size:
    20 amino acids
    Molecular mass:
    2350 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ61 Gene

Post-translational modifications for TRAJ61 Gene

No Post-translational modifications

Other Protein References for TRAJ61 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ61 Gene

Domains & Families for TRAJ61 Gene

Gene Families for TRAJ61 Gene

Protein Domains for TRAJ61 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ61: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ61 Gene

Function for TRAJ61 Gene

Phenotypes From GWAS Catalog for TRAJ61 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ61 Gene

Localization for TRAJ61 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ61 Gene

Pathways & Interactions for TRAJ61 Gene

SuperPathways for TRAJ61 Gene

No Data Available

Interacting Proteins for TRAJ61 Gene

Gene Ontology (GO) - Biological Process for TRAJ61 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ61 Gene

Drugs & Compounds for TRAJ61 Gene

No Compound Related Data Available

Transcripts for TRAJ61 Gene

mRNA/cDNA for TRAJ61 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ61 Gene

No ASD Table

Relevant External Links for TRAJ61 Gene

GeneLoc Exon Structure for
TRAJ61
ECgene alternative splicing isoforms for
TRAJ61

Expression for TRAJ61 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ61 Gene:

TRAJ61
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ61 Gene

Orthologs for TRAJ61 Gene

Evolution for TRAJ61 Gene

ENSEMBL:
Gene Tree for TRAJ61 (if available)
TreeFam:
Gene Tree for TRAJ61 (if available)

No data available for Orthologs for TRAJ61 Gene

Paralogs for TRAJ61 Gene

No data available for Paralogs for TRAJ61 Gene

Variants for TRAJ61 Gene

Additional Variant Information for TRAJ61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ61

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ61 Gene

Disorders for TRAJ61 Gene

No disorders were found for TRAJ61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ61 Gene

Publications for TRAJ61 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58

Products for TRAJ61 Gene

Sources for TRAJ61 Gene

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