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Aliases for TRAJ51 Gene

Aliases for TRAJ51 Gene

  • T-Cell Receptor Alpha Joining 51 (Pseudogene) 2 5
  • T Cell Receptor Alpha Joining 51 (Pseudogene) 2 3
  • T Cell Receptor Alpha Joining 51 Pseudogene 2
  • T Cell Receptor Alpha Joining 51 2

External Ids for TRAJ51 Gene

Previous GeneCards Identifiers for TRAJ51 Gene

  • GC14U990340
  • GC14P020946
  • GC14P022026
  • GC14P022956

Summaries for TRAJ51 Gene

Entrez Gene Summary for TRAJ51 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ51 Gene

TRAJ51 (T-Cell Receptor Alpha Joining 51 (Pseudogene)) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ51 Gene

Genomics for TRAJ51 Gene

Regulatory Elements for TRAJ51 Gene

Enhancers for TRAJ51 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G022472 2.1 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +1.4 1365 32.0 CREB3L1 AGO1 ZFP64 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF263 SP3 METTL3 BCL2L2-PABPN1 ABHD4 MMP14 SLC7A7 MRPL52 OR6J1 TRAV18 TRAV8-5 REM2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRAJ51 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAJ51 Gene

Chromosome:
14
Start:
22,487,183 bp from pter
End:
22,487,245 bp from pter
Size:
63 bases
Orientation:
Plus strand

Genomic View for TRAJ51 Gene

Genes around TRAJ51 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ51 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ51 Gene

Proteins for TRAJ51 Gene

Post-translational modifications for TRAJ51 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRAJ51 Gene

Domains & Families for TRAJ51 Gene

Gene Families for TRAJ51 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ51: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ51 Gene

Function for TRAJ51 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ51 Gene

Localization for TRAJ51 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAJ51 Gene

Pathways & Interactions for TRAJ51 Gene

SuperPathways for TRAJ51 Gene

No Data Available

Interacting Proteins for TRAJ51 Gene

Gene Ontology (GO) - Biological Process for TRAJ51 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ51 Gene

Transcripts for TRAJ51 Gene

mRNA/cDNA for TRAJ51 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ51 Gene

No ASD Table

Relevant External Links for TRAJ51 Gene

GeneLoc Exon Structure for
TRAJ51
ECgene alternative splicing isoforms for
TRAJ51

Expression for TRAJ51 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ51 Gene:

TRAJ51
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ51 Gene

Orthologs for TRAJ51 Gene

Evolution for TRAJ51 Gene

ENSEMBL:
Gene Tree for TRAJ51 (if available)
TreeFam:
Gene Tree for TRAJ51 (if available)

No data available for Orthologs for TRAJ51 Gene

Paralogs for TRAJ51 Gene

No data available for Paralogs for TRAJ51 Gene

Variants for TRAJ51 Gene

Relevant External Links for TRAJ51 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ51

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ51 Gene

Disorders for TRAJ51 Gene

No disorders were found for TRAJ51 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ51 Gene

Publications for TRAJ51 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 64

Products for TRAJ51 Gene

Sources for TRAJ51 Gene

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