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Aliases for TRAJ41 Gene

Aliases for TRAJ41 Gene

  • T Cell Receptor Alpha Joining 41 2 3 5

External Ids for TRAJ41 Gene

Previous GeneCards Identifiers for TRAJ41 Gene

  • GC14U990350
  • GC14P020957
  • GC14P021012
  • GC14P022037
  • GC14P023026
  • GC14P023090
  • GC14P023152
  • GC14P023204
  • GC14P023265
  • GC14P023328
  • GC14P023406
  • GC14P023497
  • GC14P023586
  • GC14P023727
  • GC14P022501
  • GC14P022603
  • GC14P022579

Summaries for TRAJ41 Gene

Entrez Gene Summary for TRAJ41 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ41 Gene

TRAJ41 (T Cell Receptor Alpha Joining 41) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ41 Gene

Genomics for TRAJ41 Gene

Regulatory Elements for TRAJ41 Gene


Promoters for TRAJ41 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for TRAJ41 Gene

Chromosome:
14
Start:
22,497,657 bp from pter
End:
22,497,718 bp from pter
Size:
62 bases
Orientation:
Plus strand

Genomic View for TRAJ41 Gene

Genes around TRAJ41 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ41 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ41 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ41 Gene

Proteins for TRAJ41 Gene

  • Protein details for TRAJ41 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B702
    Recommended name:
    Protein TRAJ41
    Protein Accession:
    A0A075B702

    Protein attributes for TRAJ41 Gene

    Size:
    21 amino acids
    Molecular mass:
    2152 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ41 Gene

Post-translational modifications for TRAJ41 Gene

No Post-translational modifications

Other Protein References for TRAJ41 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ41 Gene

Domains & Families for TRAJ41 Gene

Gene Families for TRAJ41 Gene

Protein Domains for TRAJ41 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ41: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ41 Gene

Function for TRAJ41 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ41 Gene

Localization for TRAJ41 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAJ41 Gene

Pathways & Interactions for TRAJ41 Gene

SuperPathways for TRAJ41 Gene

No Data Available

Interacting Proteins for TRAJ41 Gene

Gene Ontology (GO) - Biological Process for TRAJ41 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ41 Gene

Drugs & Compounds for TRAJ41 Gene

No Compound Related Data Available

Transcripts for TRAJ41 Gene

mRNA/cDNA for TRAJ41 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ41 Gene

No ASD Table

Relevant External Links for TRAJ41 Gene

GeneLoc Exon Structure for
TRAJ41
ECgene alternative splicing isoforms for
TRAJ41

Expression for TRAJ41 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ41 Gene:

TRAJ41
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRAJ41 Gene

Orthologs for TRAJ41 Gene

Evolution for TRAJ41 Gene

ENSEMBL:
Gene Tree for TRAJ41 (if available)
TreeFam:
Gene Tree for TRAJ41 (if available)

No data available for Orthologs for TRAJ41 Gene

Paralogs for TRAJ41 Gene

No data available for Paralogs for TRAJ41 Gene

Variants for TRAJ41 Gene

Relevant External Links for TRAJ41 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ41

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ41 Gene

Disorders for TRAJ41 Gene

No disorders were found for TRAJ41 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ41 Gene

Publications for TRAJ41 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 65

Products for TRAJ41 Gene

Sources for TRAJ41 Gene

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