Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TRAJ33 Gene

Aliases for TRAJ33 Gene

  • T Cell Receptor Alpha Joining 33 2 3
  • T-Cell Receptor Alpha Joining 33 5

External Ids for TRAJ33 Gene

Previous GeneCards Identifiers for TRAJ33 Gene

  • GC14U990358
  • GC14P020967
  • GC14P022048
  • GC14P023036
  • GC14P023100
  • GC14P023160
  • GC14P023212
  • GC14P023273
  • GC14P023341
  • GC14P023414
  • GC14P023506
  • GC14P023598
  • GC14P023735
  • GC14P022512
  • GC14P022619
  • GC14P022685
  • GC14P022777
  • GC14P022878
  • GC14P023837
  • GC14P023983

Summaries for TRAJ33 Gene

Entrez Gene Summary for TRAJ33 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ33 Gene

TRAJ33 (T Cell Receptor Alpha Joining 33) is a Protein Coding gene.

Additional gene information for TRAJ33 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ33 Gene

Genomics for TRAJ33 Gene

GeneHancer (GH) Regulatory Elements for TRAJ33 Gene

Promoters and enhancers for TRAJ33 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I022504 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.6 29586 66.7 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 GC14P024183 GC14P024201 TRAJ6 TRAJ7 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRAJ33 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRAJ33 Gene

Genomic Locations for TRAJ33 Gene
chr14:22,508,602-22,508,658
(GRCh38/hg38)
Size:
57 bases
Orientation:
Plus strand
chr14:22,977,587-22,977,643
(GRCh37/hg19)

Genomic View for TRAJ33 Gene

Genes around TRAJ33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ33 Gene

Proteins for TRAJ33 Gene

  • Protein details for TRAJ33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6W3
    Recommended name:
    T-cell receptor alpha joining 33
    Protein Accession:
    A0A075B6W3

    Protein attributes for TRAJ33 Gene

    Size:
    19 amino acids
    Molecular mass:
    2129 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ33 Gene

Post-translational modifications for TRAJ33 Gene

No Post-translational modifications

Other Protein References for TRAJ33 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ33 Gene

Domains & Families for TRAJ33 Gene

Gene Families for TRAJ33 Gene

Protein Domains for TRAJ33 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ33: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ33 Gene

Function for TRAJ33 Gene

Phenotypes From GWAS Catalog for TRAJ33 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ33 Gene

Localization for TRAJ33 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ33 Gene

Pathways & Interactions for TRAJ33 Gene

SuperPathways for TRAJ33 Gene

No Data Available

Interacting Proteins for TRAJ33 Gene

Gene Ontology (GO) - Biological Process for TRAJ33 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ33 Gene

Drugs & Compounds for TRAJ33 Gene

No Compound Related Data Available

Transcripts for TRAJ33 Gene

mRNA/cDNA for TRAJ33 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ33 Gene

No ASD Table

Relevant External Links for TRAJ33 Gene

GeneLoc Exon Structure for
TRAJ33
ECgene alternative splicing isoforms for
TRAJ33

Expression for TRAJ33 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ33 Gene:

TRAJ33
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ33 Gene

Orthologs for TRAJ33 Gene

Evolution for TRAJ33 Gene

ENSEMBL:
Gene Tree for TRAJ33 (if available)
TreeFam:
Gene Tree for TRAJ33 (if available)

No data available for Orthologs for TRAJ33 Gene

Paralogs for TRAJ33 Gene

No data available for Paralogs for TRAJ33 Gene

Variants for TRAJ33 Gene

Additional Variant Information for TRAJ33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ33 Gene

Disorders for TRAJ33 Gene

No disorders were found for TRAJ33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ33 Gene

Publications for TRAJ33 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58

Products for TRAJ33 Gene

Sources for TRAJ33 Gene

Content
Loading form....