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TRAJ28 Gene(Protein Coding)

T Cell Receptor Alpha Joining 28

GCID:
GC14P024096
GIFtS:
11
Genes Participants
UDN Logo

Aliases for TRAJ28 Gene

Aliases for TRAJ28 Gene

  • T Cell Receptor Alpha Joining 28 2 3
  • T-Cell Receptor Alpha Joining 28 5

External Ids for TRAJ28 Gene

Previous GeneCards Identifiers for TRAJ28 Gene

  • GC14U990363
  • GC14P020974
  • GC14P022054
  • GC14P023041
  • GC14P023105
  • GC14P023165
  • GC14P023217
  • GC14P023278
  • GC14P023346
  • GC14P023419
  • GC14P023512
  • GC14P023603
  • GC14P023740
  • GC14P022525
  • GC14P022626
  • GC14P022696
  • GC14P022787
  • GC14P022884
  • GC14P023850
  • GC14P023988

Summaries for TRAJ28 Gene

Entrez Gene Summary for TRAJ28 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ28 Gene

TRAJ28 (T Cell Receptor Alpha Joining 28) is a Protein Coding gene.

Additional gene information for TRAJ28 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ28 Gene

Genomics for TRAJ28 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for TRAJ28 Gene

Promoters and enhancers for TRAJ28 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH14I022504 Promoter/Enhancer 2.3 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +22.6 22565 66.7 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 GC14P024183 GC14P024201 TRAJ6 TRAJ7 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRAJ28 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRAJ28 Gene

Genomic Locations for TRAJ28 Gene
chr14:22,515,623-22,515,688
(GRCh38/hg38)
Size:
66 bases
Orientation:
Plus strand
chr14:22,984,601-22,984,666
(GRCh37/hg19)

Genomic View for TRAJ28 Gene

Genes around TRAJ28 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ28 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ28 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TRAJ28 Gene

Proteins for TRAJ28 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TRAJ28 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6X4
    Recommended name:
    T-cell receptor alpha joining 28
    Protein Accession:
    A0A075B6X4

    Protein attributes for TRAJ28 Gene

    Size:
    22 amino acids
    Molecular mass:
    2286 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ28 Gene

Post-translational modifications for TRAJ28 Gene

No Post-translational modifications

Other Protein References for TRAJ28 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ28 Gene

Domains & Families for TRAJ28 Gene

Gene Families for TRAJ28 Gene

HGNC:

Protein Domains for TRAJ28 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ28: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ28 Gene

Function for TRAJ28 Gene

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  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for TRAJ28 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ28 Gene

Localization for TRAJ28 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ28 Gene

Pathways & Interactions for TRAJ28 Gene

SuperPathways for TRAJ28 Gene

PathCards logo More details on SuperPathways for TRAJ28
No Data Available

Interacting Proteins for TRAJ28 Gene

Gene Ontology (GO) - Biological Process for TRAJ28 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ28 Gene

Drugs & Compounds for TRAJ28 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TRAJ28 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for TRAJ28 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ28 Gene

No ASD Table

Relevant External Links for TRAJ28 Gene

GeneLoc Exon Structure for
TRAJ28
ECgene alternative splicing isoforms for
TRAJ28

Expression for TRAJ28 Gene

Products:

  1. Primer

NURSA nuclear receptor signaling pathways regulating expression of TRAJ28 Gene:

TRAJ28
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ28 Gene

Orthologs for TRAJ28 Gene

Evolution for TRAJ28 Gene

ENSEMBL:
Gene Tree for TRAJ28 (if available)
TreeFam:
Gene Tree for TRAJ28 (if available)

No data available for Orthologs for TRAJ28 Gene

Paralogs for TRAJ28 Gene

No data available for Paralogs for TRAJ28 Gene

Variants for TRAJ28 Gene

Additional Variant Information for TRAJ28 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ28

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ28 Gene

Disorders for TRAJ28 Gene

No disorders were found for TRAJ28 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ28 Gene

Publications for TRAJ28 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58

Products for TRAJ28 Gene

Sources for TRAJ28 Gene

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