Aliases for TRAJ28 Gene
External Ids for TRAJ28 Gene
- HGNC: 12057
- Entrez Gene: 28727
- Ensembl: ENSG00000211861
Previous GeneCards Identifiers for TRAJ28 Gene
- GC14U990363
- GC14P020974
- GC14P022054
- GC14P023041
- GC14P023105
- GC14P023165
- GC14P023217
- GC14P023278
- GC14P023346
- GC14P023419
- GC14P023512
- GC14P023603
- GC14P023740
- GC14P022525
- GC14P022626
- GC14P022696
- GC14P022787
- GC14P022884
- GC14P023850
- GC14P023988
Summaries for TRAJ28 Gene
-
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]
GeneCards Summary for TRAJ28 Gene
TRAJ28 (T Cell Receptor Alpha Joining 28) is a Protein Coding gene.
Additional gene information for TRAJ28 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ28 Gene
Genomics for TRAJ28 Gene
GeneHancer (GH) Regulatory Elements for TRAJ28 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH14I022504 | Promoter/Enhancer | 2.3 | FANTOM5 Ensembl ENCODE dbSUPER | 0.3 | +22.6 | 22565 | 66.7 | MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 | GC14P024183 GC14P024201 TRAJ6 TRAJ7 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC |
Regulatory Element Products
Genomic Locations for TRAJ28 Gene
- chr14:22,515,623-22,515,688
- (GRCh38/hg38)
- Size:
- 66 bases
- Orientation:
- Plus strand
- chr14:22,984,601-22,984,666
- (GRCh37/hg19)
Genomic View for TRAJ28 Gene
- Cytogenetic band:
-
- 14q11.2 by Ensembl
- 14q11.2 by Entrez Gene
- 14q11.2 by HGNC


RefSeq DNA sequence for TRAJ28 Gene
Proteins for TRAJ28 Gene
-
Protein details for TRAJ28 Gene (UniProtKB/TrEMBL)
- Protein Symbol:
- A0A075B6X4
- Recommended name:
- T-cell receptor alpha joining 28
- Protein Accession:
- A0A075B6X4
Protein attributes for TRAJ28 Gene
- Size:
- 22 amino acids
- Molecular mass:
- 2286 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for TRAJ28 Gene
Other Protein References for TRAJ28 Gene
- ENSEMBL proteins:
Antibody Products
- Search GeneTex for Antibodies for TRAJ28
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRAJ28
- Origene Custom Protein Services for TRAJ28
- Search GeneTex for Proteins for TRAJ28
No data available for DME Specific Peptides for TRAJ28 Gene
Domains & Families for TRAJ28 Gene
Gene Families for TRAJ28 Gene
Protein Domains for TRAJ28 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ28 Gene
Function for TRAJ28 Gene
Phenotypes From GWAS Catalog for TRAJ28 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRAJ28
-
- Search ViGene Biosciences for TRAJ28
CRISPR Products
- Browse CRISPR knockouts for TRAJ28
- Applied Biological Materials CRISPR for TRAJ28
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for TRAJ28
Inhibitory RNA Products
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Clone Products
- GenScript: Custom all cDNA clones Services for TRAJ28
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRAJ28
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ28 Gene
Localization for TRAJ28 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ28 Gene
Transcripts for TRAJ28 Gene
mRNA/cDNA for TRAJ28 Gene
- (1) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for TRAJ28
- Applied Biological Materials CRISPR for TRAJ28
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for TRAJ28
Inhibitory RNA Products
- Search ViGene Biosciences for TRAJ28
Clone Products
- GenScript: Custom all cDNA clones Services for TRAJ28
- VectorBuilder custom plasmid, inducible vectors for TRAJ28
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRAJ28
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRAJ28
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for TRAJ28 Gene
NURSA nuclear receptor signaling pathways regulating expression of TRAJ28 Gene:
TRAJ28Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ28 Gene
Orthologs for TRAJ28 Gene
No data available for Orthologs for TRAJ28 Gene
Paralogs for TRAJ28 Gene
No data available for Paralogs for TRAJ28 Gene
Variants for TRAJ28 Gene
Additional Variant Information for TRAJ28 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TRAJ28
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ28 Gene
Disorders for TRAJ28 Gene
No disorders were found for TRAJ28 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ28 Gene
Publications for TRAJ28 Gene
- The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58
Products for TRAJ28 Gene
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRAJ28
- VectorBuilder custom plasmid, inducible vectors for TRAJ28
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRAJ28
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for TRAJ28
- Search GeneTex for Proteins for TRAJ28
Sources for TRAJ28 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew