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Aliases for TRAJ19 Gene

Aliases for TRAJ19 Gene

  • T-Cell Receptor Alpha Joining 19 (Non-Functional) 2 5
  • T Cell Receptor Alpha Joining 19 (Non-Functional) 2 3
  • T Cell Receptor Alpha Joining 19 2

External Ids for TRAJ19 Gene

Previous GeneCards Identifiers for TRAJ19 Gene

  • GC14U990372
  • GC14P020984
  • GC14P022064
  • GC14P023050
  • GC14P023114
  • GC14P023176
  • GC14P023226
  • GC14P023287
  • GC14P023366
  • GC14P023437
  • GC14P023521
  • GC14P023613
  • GC14P023751
  • GC14P022537
  • GC14P022644
  • GC14P022712
  • GC14P022799
  • GC14P022899

Summaries for TRAJ19 Gene

Entrez Gene Summary for TRAJ19 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ19 Gene

TRAJ19 (T-Cell Receptor Alpha Joining 19 (Non-Functional)) is a Protein Coding gene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ19 Gene

Genomics for TRAJ19 Gene

Genomic Location for TRAJ19 Gene

Chromosome:
14
Start:
22,525,263 bp from pter
End:
22,525,322 bp from pter
Size:
60 bases
Orientation:
Plus strand

Genomic View for TRAJ19 Gene

Genes around TRAJ19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ19 Gene

No data available for Regulatory Elements for TRAJ19 Gene

Proteins for TRAJ19 Gene

  • Protein details for TRAJ19 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6Y4
    Recommended name:
    T-cell receptor alpha joining 19 (non-functional)
    Protein Accession:
    A0A075B6Y4

    Protein attributes for TRAJ19 Gene

    Size:
    20 amino acids
    Molecular mass:
    2403 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ19 Gene

Post-translational modifications for TRAJ19 Gene

No Post-translational modifications

Other Protein References for TRAJ19 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ19 Gene

Domains & Families for TRAJ19 Gene

Gene Families for TRAJ19 Gene

Protein Domains for TRAJ19 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ19: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ19 Gene

Function for TRAJ19 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ19 Gene

Localization for TRAJ19 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAJ19 Gene

Pathways & Interactions for TRAJ19 Gene

SuperPathways for TRAJ19 Gene

No Data Available

Interacting Proteins for TRAJ19 Gene

Gene Ontology (GO) - Biological Process for TRAJ19 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ19 Gene

Transcripts for TRAJ19 Gene

mRNA/cDNA for TRAJ19 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ19 Gene

No ASD Table

Relevant External Links for TRAJ19 Gene

GeneLoc Exon Structure for
TRAJ19
ECgene alternative splicing isoforms for
TRAJ19

Expression for TRAJ19 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ19 Gene:

TRAJ19
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ19 Gene

Orthologs for TRAJ19 Gene

Evolution for TRAJ19 Gene

ENSEMBL:
Gene Tree for TRAJ19 (if available)
TreeFam:
Gene Tree for TRAJ19 (if available)

No data available for Orthologs for TRAJ19 Gene

Paralogs for TRAJ19 Gene

No data available for Paralogs for TRAJ19 Gene

Variants for TRAJ19 Gene

Relevant External Links for TRAJ19 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ19 Gene

Disorders for TRAJ19 Gene

No disorders were found for TRAJ19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ19 Gene

Publications for TRAJ19 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 64

Products for TRAJ19 Gene

Sources for TRAJ19 Gene

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