Aliases for TRAJ16 Gene
External Ids for TRAJ16 Gene
- HGNC: 12044
- Entrez Gene: 28739
- Ensembl: ENSG00000211873
Previous GeneCards Identifiers for TRAJ16 Gene
- GC14U990375
- GC14P020987
- GC14P022067
- GC14P023053
- GC14P023117
- GC14P023179
- GC14P023229
- GC14P023291
- GC14P023370
- GC14P023440
- GC14P023524
- GC14P023616
- GC14P023754
- GC14P022545
- GC14P022649
- GC14P022722
- GC14P022802
- GC14P022902
- GC14P023893
- GC14P024001
Summaries for TRAJ16 Gene
-
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]
GeneCards Summary for TRAJ16 Gene
TRAJ16 (T Cell Receptor Alpha Joining 16) is a Protein Coding gene.
Additional gene information for TRAJ16 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ16 Gene
Genomics for TRAJ16 Gene
GeneHancer (GH) Regulatory Elements for TRAJ16 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH14I022504 | Promoter/Enhancer | 2.3 | FANTOM5 Ensembl ENCODE dbSUPER | 0.4 | +9.7 | 9661 | 66.7 | MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 SP3 SSRP1 | GC14P024183 GC14P024201 TRAJ6 TRAJ7 ABHD4 DAD1 C14orf93 MMP14 LOC105370399 TRAC |
Regulatory Element Products
Genomic Locations for TRAJ16 Gene
- chr14:22,528,527-22,528,586
- (GRCh38/hg38)
- Size:
- 60 bases
- Orientation:
- Plus strand
- chr14:22,997,487-22,997,546
- (GRCh37/hg19)
Genomic View for TRAJ16 Gene
- Cytogenetic band:
-
- 14q11.2 by Ensembl
- 14q11.2 by Entrez Gene
- 14q11.2 by HGNC


RefSeq DNA sequence for TRAJ16 Gene
Proteins for TRAJ16 Gene
-
Protein details for TRAJ16 Gene (UniProtKB/TrEMBL)
- Protein Symbol:
- A0A075B6V0
- Recommended name:
- T-cell receptor alpha joining 16
- Protein Accession:
- A0A075B6V0
Protein attributes for TRAJ16 Gene
- Size:
- 20 amino acids
- Molecular mass:
- 2251 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for TRAJ16 Gene
Other Protein References for TRAJ16 Gene
- ENSEMBL proteins:
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRAJ16
- Origene Custom Protein Services for TRAJ16
- Search GeneTex for Proteins for TRAJ16
No data available for DME Specific Peptides for TRAJ16 Gene
Domains & Families for TRAJ16 Gene
Gene Families for TRAJ16 Gene
Protein Domains for TRAJ16 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ16 Gene
Function for TRAJ16 Gene
Phenotypes From GWAS Catalog for TRAJ16 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRAJ16
-
- Search ViGene Biosciences for TRAJ16
CRISPR Products
- Browse CRISPR knockouts for TRAJ16
- Applied Biological Materials CRISPR for TRAJ16
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for TRAJ16
Inhibitory RNA Products
- Search ViGene Biosciences for TRAJ16
Clone Products
- GenScript: Custom all cDNA clones Services for TRAJ16
- VectorBuilder custom plasmid, inducible vectors for TRAJ16
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRAJ16
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRAJ16
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ16 Gene
Localization for TRAJ16 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ16 Gene
Transcripts for TRAJ16 Gene
mRNA/cDNA for TRAJ16 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for TRAJ16
- Applied Biological Materials CRISPR for TRAJ16
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for TRAJ16
Inhibitory RNA Products
- Search ViGene Biosciences for TRAJ16
Clone Products
- GenScript: Custom all cDNA clones Services for TRAJ16
- VectorBuilder custom plasmid, inducible vectors for TRAJ16
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRAJ16
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for TRAJ16
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for TRAJ16 Gene
NURSA nuclear receptor signaling pathways regulating expression of TRAJ16 Gene:
TRAJ16Primer Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ16 Gene
Orthologs for TRAJ16 Gene
No data available for Orthologs for TRAJ16 Gene
Paralogs for TRAJ16 Gene
No data available for Paralogs for TRAJ16 Gene
Variants for TRAJ16 Gene
Additional Variant Information for TRAJ16 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- TRAJ16
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ16 Gene
Disorders for TRAJ16 Gene
No disorders were found for TRAJ16 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ16 Gene
Publications for TRAJ16 Gene
- The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 58
Products for TRAJ16 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TRAJ16
- Origene Custom Protein Services for TRAJ16
- Browse OriGene Inhibitory RNA Products For TRAJ16
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for TRAJ16
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For TRAJ16
- GenScript: Custom all cDNA clones Services for TRAJ16
- GenScript Custom Purified and Recombinant Proteins Services for TRAJ16
- GenScript Custom Assay Services for TRAJ16
- GenScript Custom overexpressing Cell Line Services for TRAJ16
- Browse GenScript CRISPR for TRAJ16
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for TRAJ16
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for TRAJ16
- VectorBuilder custom plasmid, inducible vectors for TRAJ16
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for TRAJ16
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for TRAJ16
- Search GeneTex for Proteins for TRAJ16
Sources for TRAJ16 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew