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Aliases for TRAJ12 Gene

Aliases for TRAJ12 Gene

  • T-Cell Receptor Alpha Joining 12 2 5
  • T Cell Receptor Alpha Joining 12 2 3

External Ids for TRAJ12 Gene

Previous GeneCards Identifiers for TRAJ12 Gene

  • GC14U990379
  • GC14P020991
  • GC14P022072
  • GC14P023057
  • GC14P023121
  • GC14P023183
  • GC14P023233
  • GC14P023295
  • GC14P023374
  • GC14P023444
  • GC14P023528
  • GC14P023620
  • GC14P023759
  • GC14P022549
  • GC14P022655
  • GC14P022727
  • GC14P022805
  • GC14P022906
  • GC14P023897

Summaries for TRAJ12 Gene

Entrez Gene Summary for TRAJ12 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ12 Gene

TRAJ12 (T-Cell Receptor Alpha Joining 12) is a Protein Coding gene.

Additional gene information for TRAJ12 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ12 Gene

Genomics for TRAJ12 Gene

Genomic Locations for TRAJ12 Gene

Genomic Locations for TRAJ12 Gene
60 bases
Plus strand

Genomic View for TRAJ12 Gene

Genes around TRAJ12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ12 Gene

No data available for Regulatory Elements for TRAJ12 Gene

Proteins for TRAJ12 Gene

  • Protein details for TRAJ12 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor alpha joining 12
    Protein Accession:

    Protein attributes for TRAJ12 Gene

    20 amino acids
    Molecular mass:
    2252 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ12 Gene

Post-translational modifications for TRAJ12 Gene

No Post-translational modifications

Other Protein References for TRAJ12 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ12 Gene

Domains & Families for TRAJ12 Gene

Gene Families for TRAJ12 Gene

Protein Domains for TRAJ12 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ12: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ12 Gene

Function for TRAJ12 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ12 Gene

Localization for TRAJ12 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TRAJ12 Gene

Pathways & Interactions for TRAJ12 Gene

SuperPathways for TRAJ12 Gene

No Data Available

Interacting Proteins for TRAJ12 Gene

Gene Ontology (GO) - Biological Process for TRAJ12 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRAJ12 Gene

Drugs & Compounds for TRAJ12 Gene

No Compound Related Data Available

Transcripts for TRAJ12 Gene

mRNA/cDNA for TRAJ12 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ12 Gene

No ASD Table

Relevant External Links for TRAJ12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRAJ12 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ12 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAJ12 Gene

Orthologs for TRAJ12 Gene

Evolution for TRAJ12 Gene

Gene Tree for TRAJ12 (if available)
Gene Tree for TRAJ12 (if available)

No data available for Orthologs for TRAJ12 Gene

Paralogs for TRAJ12 Gene

No data available for Paralogs for TRAJ12 Gene

Variants for TRAJ12 Gene

Relevant External Links for TRAJ12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ12 Gene

Disorders for TRAJ12 Gene

No disorders were found for TRAJ12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAJ12 Gene

Publications for TRAJ12 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 60
  2. Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor alpha-chain. (PMID: 2993909) Yoshikai Y … Mak TW (Nature 1985) 2 3 60

Products for TRAJ12 Gene

Sources for TRAJ12 Gene

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