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Aliases for TRAJ10 Gene

Aliases for TRAJ10 Gene

  • T Cell Receptor Alpha Joining 10 2 3 5

External Ids for TRAJ10 Gene

Previous GeneCards Identifiers for TRAJ10 Gene

  • GC14U990381
  • GC14P020993
  • GC14P021010
  • GC14P022075
  • GC14P023059
  • GC14P023123
  • GC14P023185
  • GC14P023236
  • GC14P023297
  • GC14P023376
  • GC14P023446
  • GC14P023531
  • GC14P023622
  • GC14P023761
  • GC14P022551
  • GC14P022657
  • GC14P022729

Summaries for TRAJ10 Gene

Entrez Gene Summary for TRAJ10 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAJ10 Gene

TRAJ10 (T Cell Receptor Alpha Joining 10) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAJ10 Gene

Genomics for TRAJ10 Gene

Genomic Location for TRAJ10 Gene

Chromosome:
14
Start:
22,533,497 bp from pter
End:
22,533,560 bp from pter
Size:
64 bases
Orientation:
Plus strand

Genomic View for TRAJ10 Gene

Genes around TRAJ10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAJ10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAJ10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAJ10 Gene

No data available for Regulatory Elements for TRAJ10 Gene

Proteins for TRAJ10 Gene

  • Protein details for TRAJ10 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0N4Z7
    Recommended name:
    Possible J 10 gene
    Protein Accession:
    A0N4Z7

    Protein attributes for TRAJ10 Gene

    Size:
    21 amino acids
    Molecular mass:
    2147 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAJ10 Gene

Post-translational modifications for TRAJ10 Gene

No Post-translational modifications

Other Protein References for TRAJ10 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAJ10 Gene

Domains & Families for TRAJ10 Gene

Gene Families for TRAJ10 Gene

Protein Domains for TRAJ10 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAJ10: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAJ10 Gene

Function for TRAJ10 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAJ10 Gene

Localization for TRAJ10 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAJ10 Gene

Pathways & Interactions for TRAJ10 Gene

SuperPathways for TRAJ10 Gene

No Data Available

Interacting Proteins for TRAJ10 Gene

Gene Ontology (GO) - Biological Process for TRAJ10 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAJ10 Gene

Drugs & Compounds for TRAJ10 Gene

No Compound Related Data Available

Transcripts for TRAJ10 Gene

mRNA/cDNA for TRAJ10 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRAJ10 Gene

No ASD Table

Relevant External Links for TRAJ10 Gene

GeneLoc Exon Structure for
TRAJ10
ECgene alternative splicing isoforms for
TRAJ10

Expression for TRAJ10 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAJ10 Gene:

TRAJ10
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRAJ10 Gene

Orthologs for TRAJ10 Gene

Evolution for TRAJ10 Gene

ENSEMBL:
Gene Tree for TRAJ10 (if available)
TreeFam:
Gene Tree for TRAJ10 (if available)

No data available for Orthologs for TRAJ10 Gene

Paralogs for TRAJ10 Gene

No data available for Paralogs for TRAJ10 Gene

Variants for TRAJ10 Gene

Relevant External Links for TRAJ10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAJ10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAJ10 Gene

Disorders for TRAJ10 Gene

Relevant External Links for TRAJ10

Genetic Association Database (GAD)
TRAJ10

No disorders were found for TRAJ10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRAJ10 Gene

Publications for TRAJ10 Gene

  1. Narcolepsy is strongly associated with the T-cell receptor alpha locus. (PMID: 19412176) Hallmayer J. … Mignot E. (Nat. Genet. 2009) 3 46 65
  2. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 65

Products for TRAJ10 Gene

Sources for TRAJ10 Gene

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