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TRAF3IP3 Gene

protein-coding   GIFtS: 55
GCID: GC01P209929

TRAF3 Interacting Protein 3

  Search for TRAF3IP3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
TRAF3 Interacting Protein 31 2
T3JAM2 3 5
TRAF3 Interacting Jun N Terminal Kinase (JNK) Activating Modulator1 2
TRAF3-Interacting JNK-Activating Modulator2
TRAF3-Interacting Protein 33

External Ids:    HGNC: 307661   Entrez Gene: 803422   Ensembl: ENSG000000097907   OMIM: 6082555   UniProtKB: Q9Y2283   
ORGUL members:         

Export aliases for TRAF3IP3 gene to outside databases

Previous GC identifers: GC01P206318 GC01P207996 GC01P180604


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRAF3IP3 Gene:
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction
pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A
catalytic subunit. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Dec 2013)

GeneCards Summary for TRAF3IP3 Gene:
TRAF3IP3 (TRAF3 interacting protein 3) is a protein-coding gene. An important paralog of this gene is CCDC136.

UniProtKB/Swiss-Prot: T3JAM_HUMAN, Q9Y228
Function: May function as an adapter molecule that regulates TRAF3-mediated JNK activation (By similarity)

Gene Wiki entry for TRAF3IP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRAF3IP3 gene promoter:
         Pbx1a   AML1a   AP-1   ATF-2   NF-kappaB   NF-kappaB2   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAF3IP3 promoter sequence
   Search Chromatin IP Primers for TRAF3IP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRAF3IP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.2   HGNC cytogenetic band: 1q32.3-q41

TRAF3IP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAF3IP3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P209929:  view genomic region     (about GC identifiers)

Start:
209,929,377 bp from pter      End:
209,955,668 bp from pter
Size:
26,292 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: T3JAM_HUMAN, Q9Y228 (See protein sequence)
Recommended Name: TRAF3-interacting JNK-activating modulator  
Size: 551 amino acids; 63626 Da
Subunit: Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain (By similarity)
Secondary accessions: A1L464 A6NIU9 Q2YDB5 Q4VY06 Q7Z706
Alternative splicing: 3 isoforms:  Q9Y228-1   Q9Y228-2   Q9Y228-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRAF3IP3: NX_Q9Y228

Explore proteomics data for TRAF3IP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys267
  • Modification sites at PhosphoSitePlus

  • See TRAF3IP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001274683.1  NP_079504.2  

    ENSEMBL proteins: 
     ENSP00000383743   ENSP00000355992   ENSP00000417665   ENSP00000419180   ENSP00000355993  
     ENSP00000355991   ENSP00000355990   ENSP00000418906   ENSP00000417417   ENSP00000436982  
     ENSP00000010338  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9Y228


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T3JAM_HUMAN, Q9Y228
    Function: May function as an adapter molecule that regulates TRAF3-mediated JNK activation (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0005515protein binding IPI18782753
         
    Find genes that share ontologies with TRAF3IP3           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Traf3ip3):
     hematopoietic system  immune system  integument 

    Find genes that share phenotypes with TRAF3IP3           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRAF3IP3
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    T3JAM_HUMAN, Q9Y228: Membrane; Single-pass type IV membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TRAF3IP3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAF3IP3
    Interactions:

        GeneGlobe Interaction Network for TRAF3IP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRAF3IP3 (Q9Y2281, 2, 3 ENSP000000103384) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK24Q9Y6E01, 3, ENSP000003657304EBI-765817,EBI-740175 I2D: score=2 STRING: ENSP00000365730
    STRNO438151, 3, ENSP000002639184EBI-765817,EBI-1046642 I2D: score=2 STRING: ENSP00000263918
    MOB4Q9Y3A31, 3, ENSP000003157024EBI-765817,EBI-713935 I2D: score=2 STRING: ENSP00000315702
    SIKE1Q9BRV81, 3, ENSP000003585414EBI-765817,EBI-1773646 I2D: score=2 STRING: ENSP00000358541
    STRIP1Q5VSL91, 3, ENSP000003588104EBI-765817,EBI-1773588 I2D: score=2 STRING: ENSP00000358810
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated ----

    Find genes that share ontologies with TRAF3IP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for TRAF3IP3 (T3JAM)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRAF3IP3 gene (2 alternative transcripts): 
    NM_001287754.1  NM_025228.3  

    Unigene Cluster for TRAF3IP3:

    TRAF3 interacting protein 3
    Hs.147434  [show with all ESTs]
    Unigene Representative Sequence: AK126139
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000400959 ENST00000367025(uc001hho.3 uc001hhn.3) ENST00000478359(uc001hhm.2)
    ENST00000479796 ENST00000468672 ENST00000367026 ENST00000367024(uc009xcr.3)
    ENST00000367023 ENST00000476050 ENST00000487271 ENST00000474496 ENST00000477431
    ENST00000480569 ENST00000488702 ENST00000471368 ENST00000460314 ENST00000467830
    ENST00000010338
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      QuantiFast Probe-based Assays in human, mouse, rat TRAF3IP3

    Additional mRNA sequence: 

    AK092905.1 AK122792.1 AK125601.1 AK126139.1 AK225762.1 AK300555.1 AK312755.1 AL049667.1 
    BC110302.1 BC130417.1 BC144139.1 BX648450.1 

    17 DOTS entries:

    DT.95265528  DT.101981376  DT.104872  DT.91761002  DT.101981375  DT.40122829  DT.92402538  DT.100729701 
    DT.86849076  DT.99950605  DT.40305684  DT.75196526  DT.100754168  DT.95257015  DT.95336021  DT.75167579 
    DT.92041204 

    Selected AceView cDNA sequences (see all 111):

    AW872837 BI907753 AA825845 AI417006 AA911785 BQ004970 BU617507 AL049667 
    CR603000 AA872549 CA436636 Z32860 NM_025228 AL040817 BP346300 BX648450 
    AU100107 BU753878 AU107252 CR609673 AI382035 AI373215 AI640772 BQ277340 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TRAF3IP3 (see all 13)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b · 15c ^ 16 ^
    SP1:                                                                          -     -     -           -                       -     -                           
    SP2:                                                                          -     -     -           -                       -     -     -     -     -         
    SP3:                                                                                                  -                       -     -                           
    SP4:                                                                                                  -                       -     -                       -   
    SP5:                                                                                                                                                            

    ExUns: 17a · 17b · 17c ^ 18 ^ 19a · 19b ^ 20a · 20b
    SP1:  -           -           -                     
    SP2:  -                                             
    SP3:  -                                             
    SP4:  -     -     -     -     -     -               
    SP5:                                                


    ECgene alternative splicing isoforms for TRAF3IP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRAF3IP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGTGTTGA
    TRAF3IP3 Expression
    About this image


    TRAF3IP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod Long Bone
     
     Thymus (Hematopoietic System)
             Thymus
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Skeletal Muscle (Muscoskeletal System)
             Extraocular Muscles
    TRAF3IP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRAF3IP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.147434
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TRAF3IP3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Traf3ip31 , 5 TRAF3 interacting protein 31, 5 82.91(n)1
    76.53(a)1
      1 (97.62 cM)5
    2152431  NM_153137.41  NP_694777.31 
     1931755065 
    chicken
    (Gallus gallus)
    Aves TRAF3IP31 TRAF3 interacting protein 3 57.94(n)
    48.88(a)
      419862  XM_004934989.1  XP_004935046.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAF3IP36
    TRAF3 interacting protein 3
    40(a)
    1 ↔ 1
    4(126090683-126106002)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1001453381 uncharacterized LOC100145338 51.52(n)
    40.91(a)
      100145338  NM_001126810.1  NP_001120282.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005347891 TRAF3-interacting JNK-activating modulator-like 43.78(n)
    29.92(a)
      100534789  XM_003199090.2  XP_003199138.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG174946
    --
    9(a)
    1 → many
    2L(22471804-22478575)
    worm
    (Caenorhabditis elegans)
    Secernentea M4.16
    Protein M4.1 (M4.1) mRNA, complete cds
    13(a)
    1 → many
    IV(3213772-3219513) WBGene00019766


    ENSEMBL Gene Tree for TRAF3IP3 (if available)
    TreeFam Gene Tree for TRAF3IP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRAF3IP3 gene
    CCDC1362  SLMAP2  
    2 SIMAP similar genes for TRAF3IP3 using alignment to 7 protein entries:     T3JAM_HUMAN (see all proteins):
    DKFZp586I031    SLMAP

    Find genes that share paralogs with TRAF3IP3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRAF3IP3 (see all 639)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0356644
    A colorectal cancer sample4--see VAR_0356642 P S mis40--------
    rs1859448701,2
    --209927406(+) GTCTCA/GTGGGC 1 -- us2k10--------
    rs1906082171,2
    --209927425(+) ATAAGG/TTATAT 1 -- us2k10--------
    rs1137547171,2
    C--209927448(+) AGTTCTG/-TGTGT 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs585832061,2
    C--209927449(+) TGTGT-/GT/TG 
            
    CTTTT
    1 -- us2k10--------
    rs1831809231,2
    --209927573(+) AACACC/TTTCTG 1 -- us2k10--------
    rs339233711,2
    C--209927651(+) CGGAC-/GTTTGT 1 -- us2k10--------
    rs65405521,2
    C,F,A,H--209927710(+) AGGAAT/CTCCTA 1 -- us2k111Minor allele frequency- C:0.35NA WA CSA EA 378
    rs120755951,2
    C,F--209927822(+) ATGCCC/TGTGAT 1 -- us2k17Minor allele frequency- T:0.50NA WA CSA 12
    rs1879443611,2
    --209927827(+) TGTGAC/TCGCAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRAF3IP3 (209929377 - 209955668 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TRAF3IP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2722162CNV Deletion23290073
    esv2722184CNV Deletion23290073
    esv2491231CNV Deletion19546169
    esv2722195CNV Deletion23290073
    esv2722173CNV Deletion23290073
    nsv159698CNV Loss16902084
    nsv4343CNV Loss18451855
    nsv873139CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 608255    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TRAF3IP3:
    Rectum cancer

    Find genes that share disorders with TRAF3IP3           About GenesLikeMe

    Genetic Association Database (GAD): TRAF3IP3
    Human Genome Epidemiology (HuGE) Navigator: TRAF3IP3 (1 document)

    Export disorders for TRAF3IP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRAF3IP3 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with TRAF3IP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1). (PubMed id 14572659)1, 3, 9 Dadgostar H....Cheng G. (FEBS Lett. 2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (J. Proteome Res. 2007)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. (PubMed id 18782753)1 Goudreault M.... Gingras A.C. (Mol. Cell. Proteomics 2009)
    7. Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library. (PubMed id 17868742)1 Ma X....Ma D. (Life Sci. 2007)
    8. TRAF3 interacts with Smac/DIABLO and enhances the proapoptotic effect of Smac/DIABLO in cytoplasm. (PubMed id 17277885)1 Zhang C....Wang Y. (Acta Biochim. Biophys. Sin. (Shanghai) 2007)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    10. Analysis of BCL6-interacting proteins by tandem mass spectrometry. (PubMed id 16147992)1 Miles R.R....Elenitoba-Johnson K.S. (amp 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 80342 HGNC: 30766 AceView: T3JAM Ensembl:ENSG00000009790 euGenes: HUgn80342
    ECgene: TRAF3IP3 H-InvDB: TRAF3IP3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TRAF3IP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TRAF3IP3 gene:
    Search GeneIP for patents involving TRAF3IP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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