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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRAF3IP3 Gene

protein-coding   GIFtS: 53
GCID: GC01P209929

TRAF3 Interacting Protein 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TRAF3 Interacting Protein 31 2
TRAF3 Interacting Jun N Terminal Kinase (JNK) Activating Modulator1 2
T3JAM2 3
TRAF3-Interacting Protein 32 3
DJ434O14.32
TRAF3-Interacting JNK-Activating Modulator2

External Ids:    HGNC: 307661   Entrez Gene: 803422   Ensembl: ENSG000000097907   OMIM: 6082555   UniProtKB: Q9Y2283   

Export aliases for TRAF3IP3 gene to outside databases

Previous GC identifers: GC01P206318 GC01P207996 GC01P180604


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRAF3IP3 Gene:
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction
pathway. The encoded protein may also interact with a large multiprotein assembly containing the phosphatase 2A
catalytic subunit. (provided by RefSeq, May 2010)

GeneCards Summary for TRAF3IP3 Gene: 
TRAF3IP3 (TRAF3 interacting protein 3) is a protein-coding gene. Diseases associated with TRAF3IP3 include rectum cancer, and cerebral cavernous malformations 3. GO annotations related to this gene include protein binding. An important paralog of this gene is CCDC136.

UniProtKB/Swiss-Prot: T3JAM_HUMAN, Q9Y228
Function: May function as an adapter molecule that regulates TRAF3-mediated JNK activation (By similarity)

Gene Wiki entry for TRAF3IP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRAF3IP3 gene promoter:
         Pbx1a   AML1a   AP-1   ATF-2   NF-kappaB   NF-kappaB2   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAF3IP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRAF3IP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAF3IP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32   Ensembl cytogenetic band:  1q32.2   HGNC cytogenetic band: 1q32.3-q41

TRAF3IP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAF3IP3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P209929:  view genomic region     (about GC identifiers)

Start:
209,929,377 bp from pter      End:
209,955,668 bp from pter
Size:
26,292 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: T3JAM_HUMAN, Q9Y228 (See protein sequence)
Recommended Name: TRAF3-interacting JNK-activating modulator  
Size: 551 amino acids; 63626 Da
Subunit: Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain (By similarity)
Subcellular location: Membrane; Single-pass type IV membrane protein (Potential)
Secondary accessions: A1L464 A6NIU9 Q2YDB5 Q4VY06 Q7Z706
Alternative splicing: 3 isoforms:  Q9Y228-1   Q9Y228-2   Q9Y228-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRAF3IP3: NX_Q9Y228

Explore proteomics data for TRAF3IP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y228

  • TRAF3IP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRAF3IP3 Protein Expression
    REFSEQ proteins: NP_079504.2  
    ENSEMBL proteins: 
     ENSP00000383743   ENSP00000355992   ENSP00000417665   ENSP00000419180   ENSP00000355993  
     ENSP00000355991   ENSP00000355990   ENSP00000418906   ENSP00000417417   ENSP00000436982  
     ENSP00000010338  

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    Cloud-Clone Corp. Proteins for TRAF3IP3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0016021integral to membrane IEA--

    TRAF3IP3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9Y228


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T3JAM_HUMAN, Q9Y228
    Function: May function as an adapter molecule that regulates TRAF3-mediated JNK activation (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0005515protein binding IPI18782753
         
    TRAF3IP3 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Traf3ip3):
     hematopoietic system  immune system 

    TRAF3IP3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRAF3IP3 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TRAF3IP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/40 Interacting proteins for TRAF3IP3 (Q9Y2281, 2, 3 ENSP000000103384) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STK24Q9Y6E01, 3, ENSP000003657304EBI-765817,EBI-740175 I2D: score=2 STRING: ENSP00000365730
    STRNO438151, 3, ENSP000002639184EBI-765817,EBI-1046642 I2D: score=2 STRING: ENSP00000263918
    MOB4Q9Y3A31, 3, ENSP000003157024EBI-765817,EBI-713935 I2D: score=2 STRING: ENSP00000315702
    SIKE1Q9BRV81, 3, ENSP000003585414EBI-765817,EBI-1773646 I2D: score=2 STRING: ENSP00000358541
    STRIP1Q5VSL91, 3, ENSP000003588104EBI-765817,EBI-1773588 I2D: score=2 STRING: ENSP00000358810
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----

    TRAF3IP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRAF3IP3 (T3JAM)

    Search CenterWatch for drugs/clinical trials and news about TRAF3IP3 / T3JAM

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRAF3IP3 gene: 
    NM_025228.2  

    Unigene Cluster for TRAF3IP3:

    TRAF3 interacting protein 3
    Hs.147434  [show with all ESTs]
    Unigene Representative Sequence: AK126139
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000400959 ENST00000367025(uc001hho.3 uc001hhn.3) ENST00000478359(uc001hhm.2)
    ENST00000479796 ENST00000468672 ENST00000367026 ENST00000367024(uc009xcr.3)
    ENST00000367023 ENST00000476050 ENST00000487271 ENST00000474496 ENST00000477431
    ENST00000480569 ENST00000488702 ENST00000471368 ENST00000460314 ENST00000467830
    ENST00000010338
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    Additional mRNA sequence: 

    AK092905.1 AK122792.1 AK125601.1 AK126139.1 AK225762.1 AK300555.1 AK312755.1 AL049667.1 
    BC110302.1 BC130417.1 BC144139.1 BX648450.1 

    17 DOTS entries:

    DT.95265528  DT.101981376  DT.104872  DT.91761002  DT.101981375  DT.40122829  DT.92402538  DT.100729701 
    DT.86849076  DT.99950605  DT.40305684  DT.75196526  DT.100754168  DT.95257015  DT.95336021  DT.75167579 
    DT.92041204 

    24/111 AceView cDNA sequences (see all 111):

    BI907753 CR609673 BQ004970 BX648450 AA825845 AW872837 NM_025228 BU617507 
    CR603000 AL040817 AU107252 AL049667 AA872549 AI382035 CA436636 BU753878 
    AA911785 AI417006 AU100107 Z32860 BP346300 CA449526 BF508015 AL560413 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for TRAF3IP3 (see all 13)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b · 15c ^ 16 ^
    SP1:                                                                          -     -     -           -                       -     -                           
    SP2:                                                                          -     -     -           -                       -     -     -     -     -         
    SP3:                                                                                                  -                       -     -                           
    SP4:                                                                                                  -                       -     -                       -   
    SP5:                                                                                                                                                            

    ExUns: 17a · 17b · 17c ^ 18 ^ 19a · 19b ^ 20a · 20b
    SP1:  -           -           -                     
    SP2:  -                                             
    SP3:  -                                             
    SP4:  -     -     -     -     -     -               
    SP5:                                                


    ECgene alternative splicing isoforms for TRAF3IP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRAF3IP3 expression in normal human tissues (normalized intensities)      TRAF3IP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGTGTTGA
    TRAF3IP3 Expression
    About this image


    TRAF3IP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Limb (Muscoskeletal System)    fully expand to see all 5 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod
             limb/hindlimb/leg   
     
     Blood (Extraembryonic Tissues)    fully expand to see all 4 entries
             Peripheral blood Pan-T Cells   
             pbmc   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
             Extraocular Muscles
             cavities and their linings/intraembryonic coelom/diaphragm   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
             Zeugopod Long Bone
     
     Lymph (Hematopoietic System)    fully expand to see all 2 entries
             LYMPH NODE   

    See TRAF3IP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRAF3IP3

    SOURCE GeneReport for Unigene cluster: Hs.147434
        SABiosciences Custom PCR Arrays for TRAF3IP3
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TRAF3IP3 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Traf3ip31 , 5 TRAF3 interacting protein 31, 5 82.91(n)1
    76.53(a)1
      1 (97.62 cM)5
    2152431  NM_153137.41  NP_694777.31 
     1931755065 
    chicken
    (Gallus gallus)
    Aves TRAF3IP31 TRAF3 interacting protein 3 62.8(n)
    59.6(a)
      419862  XM_417989.3  XP_417989.3 
    lizard
    (Anolis carolinensis)
    Reptilia TRAF3IP36
    Uncharacterized protein
    42(a)
    1 ↔ 1
    4(126090683-126106002)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1005347891 TRAF3-interacting JNK-activating modulator-like 44.44(n)
    30.45(a)
      100534789  XM_003199090.1  XP_003199138.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG174946
    --
    3(a)
    1 → many
    2L(22471804-22478575)
    worm
    (Caenorhabditis elegans)
    Secernentea M4.16
    Protein M4.1
    3(a)
    1 → many
    IV(3213772-3217668)


    ENSEMBL Gene Tree for TRAF3IP3 (if available)
    TreeFam Gene Tree for TRAF3IP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRAF3IP3 gene
    CCDC1362  SLMAP2  
    2 SIMAP similar genes for TRAF3IP3 using alignment to 7 protein entries:     T3JAM_HUMAN (see all proteins):
    DKFZp586I031    SLMAP

    TRAF3IP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/639 SNPs in TRAF3IP3 are shown (see all 639)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0356644
    A colorectal cancer sample4--see VAR_0356642 P S mis40--------
    rs1859448701,2
    --209927406(+) GTCTCA/GTGGGC 1 -- us2k10--------
    rs1906082171,2
    --209927425(+) ATAAGG/TTATAT 1 -- us2k10--------
    rs1137547171,2
    C--209927448(+) AGTTCTG/-TGTGT 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs585832061,2
    C--209927449(+) TGTGT-/GT/TG 
            
    CTTTT
    1 -- us2k10--------
    rs1831809231,2
    --209927573(+) AACACC/TTTCTG 1 -- us2k10--------
    rs339233711,2
    C--209927651(+) CGGAC-/GTTTGT 1 -- us2k10--------
    rs65405521,2
    C,F,A,H--209927710(+) AGGAAT/CTCCTA 1 -- us2k111Minor allele frequency- C:0.35NA WA CSA EA 378
    rs120755951,2
    C,F--209927822(+) ATGCCC/TGTGAT 1 -- us2k17Minor allele frequency- T:0.50NA WA CSA 12
    rs1879443611,2
    --209927827(+) TGTGAC/TCGCAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRAF3IP3 (209929377 - 209955668 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TRAF3IP3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2722162CNV Deletion23290073
    esv2722184CNV Deletion23290073
    esv2491231CNV Deletion19546169
    esv2722195CNV Deletion23290073
    esv2722173CNV Deletion23290073
    nsv159698CNV Loss16902084
    nsv4343CNV Loss18451855
    nsv873139CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608255    OMIM disorders: --

    5 diseases for TRAF3IP3:    About MalaCards
    rectum cancer    cerebral cavernous malformations 3    cavernous malformation    cerebral cavernous malformation
    cerebritis

    1 disease from the University of Copenhagen DISEASES database for TRAF3IP3:
    Rectum cancer

    TRAF3IP3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRAF3IP3
    Human Genome Epidemiology (HuGE) Navigator: TRAF3IP3 (1 document)

    Export disorders for TRAF3IP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRAF3IP3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with TRAF3IP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1). (PubMed id 14572659)1, 3, 9 Dadgostar H....Cheng G. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (2007)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein. (PubMed id 18782753)1 Goudreault M....Gingras A.C. (2009)
    7. Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library. (PubMed id 17868742)1 Ma X....Ma D. (2007)
    8. TRAF3 interacts with Smac/DIABLO and enhances the proapoptotic effect of Smac/DIABLO in cytoplasm. (PubMed id 17277885)1 Zhang C....Wang Y. (2007)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    10. Analysis of BCL6-interacting proteins by tandem mass spectrometry. (PubMed id 16147992)1 Miles R.R....Elenitoba-Johnson K.S. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80342 HGNC: 30766 AceView: T3JAM Ensembl:ENSG00000009790 euGenes: HUgn80342
    ECgene: TRAF3IP3 H-InvDB: TRAF3IP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRAF3IP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRAF3IP3 gene:
    Search GeneIP for patents involving TRAF3IP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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