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TRAF3IP1 Gene

protein-coding   GIFtS: 54
GCID: GC02P239229

TNF Receptor-Associated Factor 3 Interacting Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TNF Receptor-Associated Factor 3 Interacting Protein 11 2     MIP-T32 3
MIPT32 3 5     IFT542
Microtubule Interacting Protein That Associates With TRAF31 2     Interleukin 13 Receptor Alpha 1-Binding Protein-12
Interleukin-13 Receptor Alpha 1-Binding Protein 12 3     Microtubule-Interacting Protein That Associates With TRAF32
Microtubule-Interacting Protein Associated With TRAF32 3     TRAF3-Interacting Protein 12

External Ids:    HGNC: 178611   Entrez Gene: 261462   Ensembl: ENSG000002041047   OMIM: 6073805   UniProtKB: Q8TDR03   

Export aliases for TRAF3IP1 gene to outside databases

Previous GC identifers: GC02P239516 GC02P239011 GC02P238893 GC02P231020


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRAF3IP1 Gene:
TRAF3IP1 (TNF receptor-associated factor 3 interacting protein 1) is a protein-coding gene. Diseases associated with TRAF3IP1 include bardet-biedl syndrome, and schizophrenia. GO annotations related to this gene include microtubule binding.

UniProtKB/Swiss-Prot: MIPT3_HUMAN, Q8TDR0
Function: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of
IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the
microtubules




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRAF3IP1 gene promoter:
         AhR   Bach1   Pax-5   POU6F1 (c2)   Arnt   CREB   MEF-2A   deltaCREB   aMEF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRAF3IP1 promoter sequence
   Search Chromatin IP Primers for TRAF3IP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRAF3IP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

TRAF3IP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRAF3IP1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P239229:  view genomic region     (about GC identifiers)

Start:
239,229,082 bp from pter      End:
239,309,541 bp from pter
Size:
80,460 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MIPT3_HUMAN, Q8TDR0 (See protein sequence)
Recommended Name: TRAF3-interacting protein 1  
Size: 691 amino acids; 78632 Da
Subunit: Component of IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11/IFT25 and IFT20 (By
similarity). Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1
1 PDB 3D structure from and Proteopedia for TRAF3IP1:
2EQO (3D)    
Secondary accessions: Q6PCT1 Q7L8N9 Q9NRD6 Q9Y4Q1
Alternative splicing: 2 isoforms:  Q8TDR0-1   Q8TDR0-2   

Explore the universe of human proteins at neXtProt for TRAF3IP1: NX_Q8TDR0

Explore proteomics data for TRAF3IP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRAF3IP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001132962.1  NP_056465.2  

    ENSEMBL proteins: 
     ENSP00000375851   ENSP00000362424   ENSP00000386648   ENSP00000375852  

    TRAF3IP1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFT: Intraflagellar transport homologs

    1 InterPro protein domain:
     IPR018799 TRAF3IP1

    Graphical View of Domain Structure for InterPro Entry Q8TDR0

    ProtoNet protein and cluster: Q8TDR0

    UniProtKB/Swiss-Prot: MIPT3_HUMAN, Q8TDR0
    Similarity: Belongs to the TRAF3IP1 family


    TRAF3IP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MIPT3_HUMAN, Q8TDR0
    Function: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of
    IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the
    microtubules

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10791955
    GO:0008017microtubule binding IEA--
         
    TRAF3IP1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TRAF3IP1:
     Decreased nuclei size in G2M  Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Traf3ip1):
     embryogenesis  homeostasis/metabolism  limbs/digits/tail  mortality/aging  nervous system 
     vision/eye 

    TRAF3IP1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRAF3IP1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRAF3IP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRAF3IP1

    miRNA
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    miRTarBase miRNAs that target TRAF3IP1:
    hsa-mir-877-3p (MIRT037104), hsa-mir-92a-3p (MIRT049550), hsa-mir-25-3p (MIRT050269)

    Block miRNA regulation of human, mouse, rat TRAF3IP1 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate TRAF3IP1:
    hsa-miR-3163 hsa-miR-548am hsa-miR-548x hsa-miR-3613-3p hsa-miR-590-3p hsa-miR-497* hsa-miR-4282
    SwitchGear 3'UTR luciferase reporter plasmidTRAF3IP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRAF3IP1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): TRAF3IP1 (NM_015650)
    Sino Biological Human cDNA Clone for TRAF3IP1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAF3IP1

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    Browse ESI BIO Cell Lines and PureStem Progenitors for TRAF3IP1 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAF3IP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MIPT3_HUMAN, Q8TDR0: Cytoplasm, cytoskeleton. Note=Microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus3
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--

    TRAF3IP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAF3IP1
    Interactions:

        Search GeneGlobe Interaction Network for TRAF3IP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRAF3IP1 (Q8TDR01, 3 ENSP000003624244) via UniProtKB, MINT, STRING, and/or I2D (see all 82)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000237724P081073, ENSP000004063594I2D: score=1 STRING: ENSP00000406359
    ENSG00000212866P081073I2D: score=1 
    ENSG00000215328P081073I2D: score=1 
    ENSG00000224501P081073I2D: score=1 
    ENSG00000231555P081073I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRAF3IP1 (MIPT3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRAF3IP1 gene (2 alternative transcripts): 
    NM_001139490.1  NM_015650.3  

    Unigene Cluster for TRAF3IP1:

    TNF receptor-associated factor 3 interacting protein 1
    Hs.631898  [show with all ESTs]
    Unigene Representative Sequence: NM_015650
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000391993 ENST00000373327(uc002vye.3 uc002vyf.3) ENST00000409739
    ENST00000462122 ENST00000483951 ENST00000391994
    miRNA
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    Block miRNA regulation of human, mouse, rat TRAF3IP1 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate TRAF3IP1:
    hsa-miR-3163 hsa-miR-548am hsa-miR-548x hsa-miR-3613-3p hsa-miR-590-3p hsa-miR-497* hsa-miR-4282
    SwitchGear 3'UTR luciferase reporter plasmidTRAF3IP1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TRAF3IP1
    Predesigned siRNA for gene silencing in human, mouse, rat TRAF3IP1
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    GenScript: all cDNA clones in your preferred vector (see all 2): TRAF3IP1 (NM_015650)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRAF3IP1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TRAF3IP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRAF3IP1
      QuantiTect SYBR Green Assays in human, mouse, rat TRAF3IP1
      QuantiFast Probe-based Assays in human, mouse, rat TRAF3IP1

    Additional mRNA sequence: 

    AF230877.1 AF242456.1 AL080153.1 BC059174.1 

    7 DOTS entries:

    DT.431372  DT.100035539  DT.202844  DT.91885606  DT.97803160  DT.120994036  DT.75194649 

    Selected AceView cDNA sequences (see all 65):

    AI356967 BG287415 AL080153 BX280107 BQ018317 AI277907 CA488496 BU740524 
    BM727042 BQ021220 CK725158 BM563106 AW069058 AI366813 CB243230 AI383556 
    BU741288 AI499243 BE781823 BQ185199 AF230877 AW204478 AL602388 AL514628 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRAF3IP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCTGAATG
    TRAF3IP1 Expression
    About this image

    TRAF3IP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRAF3IP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.631898

    UniProtKB/Swiss-Prot: MIPT3_HUMAN, Q8TDR0
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAF3IP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TRAF3IP1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Traf3ip11 , 5 TRAF3 interacting protein 11, 5 76.7(n)1
    75.12(a)1
      1 (46.16 cM)5
    740191  NM_028718.21  NP_082994.11 
     914946685 
    chicken
    (Gallus gallus)
    Aves TRAF3IP11 NF receptor-associated factor 3 interacting protein 1 less 64.75(n)
    58.29(a)
      424029  XM_004942511.1  XP_004942568.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRAF3IP16
    TNF receptor-associated factor 3 interacting prote...
    55(a)
    1 ↔ 1
    1(118770028-118792934)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia traf3ip11 TNF receptor-associated factor 3 interacting protein 1 less 60.58(n)
    54.33(a)
      779507  NM_001171521.1  NP_001164992.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc635222 hypothetical protein MGC63522 77.15(n)   393572  BC056776.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG32596
    --
    27(a)
    1 ↔ 1
    3R(10128150-10130180)
    worm
    (Caenorhabditis elegans)
    Secernentea dyf-116
    Protein DYF-11 (dyf-11) mRNA, complete cds
    28(a)
    1 ↔ 1
    X(763769-766733) WBGene00001127


    ENSEMBL Gene Tree for TRAF3IP1 (if available)
    TreeFam Gene Tree for TRAF3IP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRAF3IP1 (see all 1792)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58396991,2
    C--238656980(+) TTTTTT/-GAGAC 2 -- int1 trp31Minor allele frequency- -:0.00NA 2
    rs1876016301,2
    --239227195(+) AACTAC/TGCAAG 2 -- us2k10--------
    rs1929514371,2
    --239227203(+) AAGCCA/GGAAGT 2 -- us2k10--------
    rs1442414961,2
    --239227250(+) AACAGA/TCAGTC 2 -- us2k10--------
    rs1465792051,2
    --239227272(+) ACTTTC/TCTTTT 2 -- us2k10--------
    rs1847534181,2
    C--239227371(+) ACCCCC/TGGGTT 2 -- us2k10--------
    rs1896269811,2
    C--239227472(+) CAGGCG/TTTCAC 2 -- us2k10--------
    rs23408861,2
    C,A--239227500(-) ggagtT/Atgaga 2 -- us2k11Minor allele frequency- A:0.50WA 2
    rs116897891,2
    C,F,H--239227533(+) ctcagC/Gctccc 2 -- us2k14Minor allele frequency- G:0.25NA 8
    rs1510041571,2
    C--239227563(+) CGTGAA/GCCACT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TRAF3IP1 (239229082 - 239309541 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TRAF3IP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669020CNV Deletion23128226
    nsv3233CNV Insertion18451855
    esv1355575CNV Insertion17803354
    nsv876068CNV Loss21882294

    Human Gene Mutation Database (HGMD): TRAF3IP1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRAF3IP1
    DNA2.0 Custom Variant and Variant Library Synthesis for TRAF3IP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607380    OMIM disorders: --

    4 diseases for TRAF3IP1:    
    About MalaCards
    bardet-biedl syndrome    schizophrenia    malaria    neuronitis

    1 disease from the University of Copenhagen DISEASES database for TRAF3IP1:
    Bardet-Biedl syndrome

    TRAF3IP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRAF3IP1
    Human Genome Epidemiology (HuGE) Navigator: TRAF3IP1 (3 documents)

    Export disorders for TRAF3IP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRAF3IP1 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with TRAF3IP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation. (PubMed id 12935900)1, 2, 3, 9 Niu Y.... Kobayashi N. (FEBS Lett. 2003)
    2. MIP-T3, a novel protein linking tumor necrosis factor receptor- associated factor 3 to the microtubule network. (PubMed id 10791955)1, 2, 3 Ling L. and Goeddel D.V. (J. Biol. Chem. 2000)
    3. GWAS findings for human iris patterns: associations with variants in genes that influence normal neuronal pattern development. (PubMed id 21835309)1, 4 Larsson M....Medland S.E. (Am. J. Hum. Genet. 2011)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses. (PubMed id 19251251)1, 4 Tomppo L....Peltonen L. (Biol. Psychiatry 2009)
    6. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. (PubMed id 19898482)1, 4 Ross C.J....Hayden M.R. (Nat. Genet. 2009)
    7. DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. (PubMed id 12812986)1, 2 Morris J.A.... Austin C.P. (Hum. Mol. Genet. 2003)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. MIP-T3 is a negative regulator of innate type I IFN response. (PubMed id 22079989)1 Ng M.H....Jin D.Y. (J. Immunol. 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26146 HGNC: 17861 AceView: TRAF3IP1 Ensembl:ENSG00000204104 euGenes: HUgn26146
    ECgene: TRAF3IP1 H-InvDB: TRAF3IP1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRAF3IP1 Pharmacogenomics, SNPs, Pathways

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