TRABD Gene
protein-coding GIFtS: 41
GCID: GC22P050624
|
|
TraB domain containing
| |
Aliases
for TRABD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TraB Domain Containing1 2 | | PP24471 2 | | LP60542 | | TraB Domain-Containing Protein2 | | TTG23 | | Protein TTG23 |
Export aliases for TRABD gene to outside databasesPrevious GC identifers: GC22P048966 GC22P033529 |
Summaries
for TRABD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TRABD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011526.7
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TRABD gene promoter:
AhR Sox5 AML1a p300 NF-E2 p45 Evi-1 Max NF-E2 c-Myc ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for TRABD
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRABD |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.33 Ensembl cytogenetic band: 22q13.33 HGNC cytogenetic band: 22q13.33TRABD Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P050624: view genomic region
(about GC identifiers)
Start:
|
50,624,344 bp from pter |
End:
|
50,638,027 bp from pter |
Size:
|
13,684 bases |
Orientation:
|
plus strand |
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Proteins
for TRABD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRABD_HUMAN, Q9H4I3 (See
protein sequence)Recommended Name: TraB domain-containing protein Size: 376 amino acids; 42321 Da
Sequence caution: Sequence=BAB15737.1; Type=Frameshift; Positions=224, 282;
Secondary accessions: Q19CC5 Q96ED8 Q9H7N1 Q9UGX6 Q9UGX7Alternative splicing: 2 isoforms: Q9H4I3-1 Q9H4I3-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TRABD: NX_Q9H4I3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H4I3
TRABD Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079480.2
ENSEMBL proteins: ENSP00000370295 ENSP00000305664 ENSP00000379171 ENSP00000379173
Human Recombinant Protein Products for TRABD:
TRABD Antibody Products:
Assay Products for TRABD: |
Protein
Domains /
Families
for TRABD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TRABD for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9H4I3ProtoNet protein and cluster: Q9H4I3 1 Blocks protein family: IPB002816 TraB determinant
|
Function
for TRABD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Phenotypes:
1 MGI phenotypic allele  for Trabd (no phenotypes)
TRABD for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TRABD (NM_025204) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRABD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRABD |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRABD |
|
Pathways & Interactions
for TRABD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRABD
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/10 Interacting proteins for TRABD (Q9H4I33 ENSP000003056644) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
|
Drugs & Compounds
for TRABD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TRABD
Search CenterWatch for drugs/clinical trials and news about TRABD
|
Transcripts
for TRABD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TRABD gene: NM_025204.2 Unigene Cluster for TRABD: TraB domain containing Hs.741417 [show with all ESTs]Unigene Representative Sequence: AY2039456 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380909 ENST00000303434(uc003bjr.2 uc003bjs.1) ENST00000463233
ENST00000395827 ENST00000395829 ENST00000472677
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TRABD (NM_025204) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRABD | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRABD |
Additional cDNA sequence: AF218001.1 AK292050.1 AK307115.1 AL449244.1 AY203945.1 BC012445.1 BC093029.1 23 DOTS entries: DT.75118447 DT.214064 DT.100877390 DT.95162062 DT.100877387 DT.40272891 DT.100877384 DT.100877391 DT.100877385 DT.95162059 DT.92436426 DT.100831688 DT.100877371 DT.92436429 DT.92436430 DT.100832178 DT.100877373 DT.100877378 DT.100877388 DT.120637651 DT.92436420 DT.100877374 DT.102845493 24/293 AceView cDNA sequences (see all 293): BQ448163 BM931162 BU151114 BM744113 AL561191 BM795389 AL561074 BI027453 BG284979 BQ052627 BQ637750 AL449244 CR607528 BM454282 BM757155 AW139687 BM982285 BX421092 BU902575 CR615428 BQ932551 CR626213 BQ943630 BM763754
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for TRABD (see all 14) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | · |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | |
| ExUns: | 11c | · | 11d | · | 11e | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for TRABD
|
Expression
for TRABD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TRABD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TRABD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TRABD
SOURCE GeneReport for Unigene cluster: Hs.741417
SABiosciences Custom PCR Arrays for TRABD
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRABD
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRABD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRABD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRABD | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRABD |
Orthologs
for TRABD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TRABD gene from 9/24 species (see all 24) About this table
ENSEMBL Gene Tree for TRABD (if available)
TreeFam Gene Tree for TRABD (if available) |
Paralogs
for TRABD gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TRABD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TRABD (50624344 - 50638027 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TRABD
2 CNVs: 30167 30166 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRABD |
|
Disorders
/ Diseases
for TRABD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TRABD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TRABD gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with TRABD) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 2 Hattori A.... Ohara O. (2000)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
- Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
|
External Searches for TRABD gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TRABD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TRABD gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TRABD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TRABD | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TRABD gene:
Search GeneIP for patents involving TRABD
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TRABD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TRABD | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRABD | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRABD | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TRABD | | OriGene 3'-UTR Clone for TRABD | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRABD | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TRABD | | OriGene Custom Protein Services for TRABD | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRABD | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRABD | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRABD | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRABD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRABD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRABD |
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| | | | Search Tocris compounds for TRABD |
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 | | | TRABD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRABD |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TRABD |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRABD |
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