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Aliases for TRABD Gene

Aliases for TRABD Gene

  • TraB Domain Containing 2 3 5
  • Protein TTG2 4
  • LP6054 3
  • PP2447 3
  • TTG2 4

External Ids for TRABD Gene

Previous GeneCards Identifiers for TRABD Gene

  • GC22P048966
  • GC22P050624
  • GC22P033529

Summaries for TRABD Gene

GeneCards Summary for TRABD Gene

TRABD (TraB Domain Containing) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRABD Gene

Genomics for TRABD Gene

Regulatory Elements for TRABD Gene

Enhancers for TRABD Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRABD on UCSC Golden Path with GeneCards custom track

Promoters for TRABD Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TRABD on UCSC Golden Path with GeneCards custom track

Genomic Location for TRABD Gene

50,185,905 bp from pter
50,199,598 bp from pter
13,694 bases
Plus strand

Genomic View for TRABD Gene

Genes around TRABD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRABD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRABD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRABD Gene

Proteins for TRABD Gene

  • Protein details for TRABD Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    TraB domain-containing protein
    Protein Accession:
    Secondary Accessions:
    • Q19CC5
    • Q96ED8
    • Q9H7N1
    • Q9UGX6
    • Q9UGX7

    Protein attributes for TRABD Gene

    376 amino acids
    Molecular mass:
    42321 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB15737.1; Type=Frameshift; Positions=224, 282; Evidence={ECO:0000305};

    Alternative splice isoforms for TRABD Gene


neXtProt entry for TRABD Gene

Proteomics data for TRABD Gene at MOPED

Post-translational modifications for TRABD Gene

  • Ubiquitination at Lys 50, Lys 116, and Lys 209
  • Modification sites at PhosphoSitePlus

Other Protein References for TRABD Gene

No data available for DME Specific Peptides for TRABD Gene

Domains & Families for TRABD Gene

Protein Domains for TRABD Gene


Suggested Antigen Peptide Sequences for TRABD Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRABD: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TRABD Gene

Function for TRABD Gene

genes like me logo Genes that share phenotypes with TRABD: view

Animal Model Products

  • Taconic Biosciences Mouse Models for TRABD

miRNA for TRABD Gene

miRTarBase miRNAs that target TRABD

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRABD Gene

Localization for TRABD Gene

Subcellular locations from

Jensen Localization Image for TRABD Gene COMPARTMENTS Subcellular localization image for TRABD gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 2
cytoskeleton 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TRABD Gene

Pathways & Interactions for TRABD Gene

SuperPathways for TRABD Gene

No Data Available

Interacting Proteins for TRABD Gene

Gene Ontology (GO) - Biological Process for TRABD Gene


No data available for Pathways by source and SIGNOR curated interactions for TRABD Gene

Drugs & Compounds for TRABD Gene

No Compound Related Data Available

Transcripts for TRABD Gene

Unigene Clusters for TRABD Gene

TraB domain containing:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TRABD Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ·
SP1: - - - -
SP2: - - - - - - -
SP3: - - - -
SP4: - - - - -
SP5: - - - - -
SP6: - - - -
SP7: - - -
SP8: - - -
SP9: - -
SP10: - - - -
SP11: -
SP12: -
SP13: -

ExUns: 11c · 11d · 11e ^ 12a · 12b
SP11: - - -

Relevant External Links for TRABD Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRABD Gene

mRNA expression in normal human tissues for TRABD Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TRABD Gene

This gene is overexpressed in Whole Blood (x6.0).

Protein differential expression in normal tissues from HIPED for TRABD Gene

This gene is overexpressed in Peripheral blood mononuclear cells (26.8), Breast (17.8), and Bone (11.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TRABD Gene

SOURCE GeneReport for Unigene cluster for TRABD Gene Hs.517731

genes like me logo Genes that share expression patterns with TRABD: view

Protein tissue co-expression partners for TRABD Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for TRABD Gene

Orthologs for TRABD Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TRABD Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TRABD 35
  • 88.21 (n)
  • 90.33 (a)
  • 79 (a)
(Canis familiaris)
Mammalia TRABD 35
  • 90.79 (n)
  • 93.39 (a)
  • 85 (a)
(Mus musculus)
Mammalia Trabd 35
  • 86.33 (n)
  • 93.83 (a)
Trabd 16
Trabd 36
  • 93 (a)
(Pan troglodytes)
Mammalia TRABD 35
  • 94.29 (n)
  • 94.29 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Trabd 35
  • 86.86 (n)
  • 93.57 (a)
(Monodelphis domestica)
Mammalia TRABD 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia TRABD 36
  • 81 (a)
(Gallus gallus)
Aves TRABD 35
  • 68.55 (n)
  • 75.47 (a)
  • 74 (a)
(Anolis carolinensis)
Reptilia TRABD 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia trabd 35
  • 67.4 (n)
  • 75.69 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.32087 35
(Danio rerio)
Actinopterygii Dr.26717 35
trabd 35
  • 68.07 (n)
  • 70.48 (a)
trabd 36
  • 66 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004340 35
  • 57.99 (n)
  • 48.26 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG12360 35
  • 56.92 (n)
  • 49.65 (a)
CG12360 36
  • 29 (a)
(Caenorhabditis elegans)
Secernentea F38A5.2 36
  • 32 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G05270 35
  • 46.84 (n)
  • 40.08 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8533 36
  • 40 (a)
Species with no ortholog for TRABD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TRABD Gene

Gene Tree for TRABD (if available)
Gene Tree for TRABD (if available)

Paralogs for TRABD Gene

No data available for Paralogs for TRABD Gene

Variants for TRABD Gene

Sequence variations from dbSNP and Humsavar for TRABD Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs7288305 -- 50,185,761(+) ggggg(C/G)ggggg upstream-variant-2KB
rs7288306 -- 50,185,769(+) GGGCC(C/T)CGCGC upstream-variant-2KB
rs2272844 -- 50,197,419(+) TCCCA(A/C/G)TGCTC intron-variant
rs7288532 -- 50,191,707(+) TGCAC(A/G)ACTAG intron-variant
rs7288889 -- 50,186,737(+) TTCAA(G/T)TGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRABD Gene

Variant ID Type Subtype PubMed ID
nsv915495 CNV Loss 21882294
dgv5051n71 CNV Loss 21882294
nsv915519 CNV Loss 21882294
dgv5054n71 CNV Loss 21882294
nsv915525 CNV Loss 21882294
dgv781n67 CNV Gain 20364138
dgv5055n71 CNV Loss 21882294
nsv829333 CNV Gain 20364138
dgv5056n71 CNV Loss 21882294
dgv5057n71 CNV Loss 21882294
nsv914511 CNV Loss 21882294
nsv914515 CNV Gain 21882294
esv2724755 CNV Deletion 23290073
esv2724756 CNV Deletion 23290073
esv2724757 CNV Deletion 23290073
nsv191327 CNV Loss 16902084
nsv471223 CNV Loss 18288195

Variation tolerance for TRABD Gene

Residual Variation Intolerance Score: 22.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.86; 18.03% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TRABD Gene

Disorders for TRABD Gene

Relevant External Links for TRABD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRABD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRABD Gene

Publications for TRABD Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  5. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3

Products for TRABD Gene

Sources for TRABD Gene