TRA@ Cluster

Aliases
for TRA@ gene

Previous GC identifers: GC14U990056 GC14P020456 GC14P021160

Summaries
for TRA@ gene

Genomic Views
for TRA@ gene

Browse SwitchGear Promoter luciferase reporter plasmids

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRA@

TRA@ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P022091:  view genomic region     (about GC identifiers)

Proteins
for TRA@ gene

UniProtKB/TrEMBL: Q6IPR8 (See protein sequence)

UniProtKB/TrEMBL: Q6IRV4 (See protein sequence)

UniProtKB/TrEMBL: Q6NS93 (See protein sequence)

UniProtKB/TrEMBL: Q6NSA0 (See protein sequence)

UniProtKB/TrEMBL: Q6NSA1 (See protein sequence)

UniProtKB/TrEMBL: Q6NSA6 (See protein sequence)

1 PDB 3D structure from and Proteopedia for TRA@:

1MI5 (3D)    

UniProtKB/TrEMBL: Q6P4G7 (See protein sequence)

1 PDB 3D structure from and Proteopedia for TRA@:

2NW2 (3D)    

UniProtKB/TrEMBL: Q6P4I7 (See protein sequence)

UniProtKB/TrEMBL: Q6PIP7 (See protein sequence)

UniProtKB/TrEMBL: Q6PJ56 (See protein sequence)

UniProtKB/TrEMBL: Q8WUD0 (See protein sequence)

Protein Domains /
Families
for TRA@ gene

ProtoNet protein and cluster: Q2YD82

Function
for TRA@ gene

Pathways & Interactions
for TRA@ gene

Drugs & Compounds
for TRA@ gene

Transcripts
for TRA@ gene

Expression
for TRA@ gene

Expression evidence for TRA@:none

See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
    SABiosciences Custom PCR Arrays for TRA@

Primer Products:		Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TRA@
		Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRA@
		Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRA@

In Situ Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TRA@

Orthologs
for TRA@ gene

Paralogs
for TRA@ gene

Genomic Variants
for TRA@ gene

10/76 NCBI SNPs in TRA@ are shown (see all 76)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 14 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1512298091,2		--	22101569(+)	ATCACA/GAGGGT	1	--	ds5001		0	--	--	--	--
rs49824741,2	C,	--	22101574(+)	GAGGGT/CGAGGG	1	--	ds5001		4		NA WA EA	360
rs1912877911,2		--	22101829(+)	TAGAGA/GTGATA	1	--	ds5001		0	--	--	--	--
rs49824751,2	C,F,A,H,	--	22101945(+)	AGAAAG/ATGAAA	1	--	ds5001		22		NS EA NA WA CSA	2350
rs1995423601,2		--	22102055(+)	ATTTTC/TATTCA	1	--	ds5001		0	--	--	--	--
rs413014571,2	C,F,	--	22103007(+)	TTTTTG/ATAGTC	1	--	us2k1		2		NA EU	1443
rs286699311,2	C,	--	22103039(+)	TTGACA/GAGAGA	1	--	us2k1		0	--	--	--	--
rs1394644791,2		--	22103083(+)	TTGTCA/GGATGA	1	--	us2k1		0	--	--	--	--
rs413014551,2	C,F,H,	--	22103133(+)	AATTGT/GTTTTT	1	--	us2k1		18		NS NA EA	1928
rs803068681,2	C,F,	--	22103201(+)	CCAGAG/TGCTGG	1	--	us2k1		1		NA	120

HapMap Linkage Disequilibrium report for TRA@ (22090057 - 22340057 bp, first 250kb of TRA@)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for TRA@: --
Locus Specific Mutation Databases (LSDB): TRA@

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRA@

DNA2.0 Custom Variant and Variant Library Synthesis for TRA@

Disorders / Diseases
for TRA@ gene

20/40 diseases for TRA@

10/16 Novoseek disease relationships for TRA@ gene (see all 16)    About this table

Publications
for TRA@ gene

PubMed articles for TRA@ gene, integrated from 9 sources (see all 211): (articles sorted by number of sources associating them with TRA@)

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1. Association study of proposed candidate genes/regions in a population of Spanish asthmatics. (PubMed id 11142503)^{1, 4} Soriano J.B....Lazaro C. (2000)
2. The chromosomal location of T-cell receptor genes and a T cell rearranging gene: possible correlation with specific translocations in human T cell leukaemia. (PubMed id 3875483)^{1, 3} Rabbitts T.H....Goodfellow P.N. (1985)
3. Locus of the alpha-chain of the T-cell receptor is split by chromosome translocation in T-cell leukemias. (PubMed id 3875152)^{1, 3} Erikson J....Croce C.M. (1985)
4. Pre T-cell receptor alpha (pTalpha) expression patter ns and functional analysis in human T-cell lymphoblastic leukemia. (PubMed id 20208138)^{1, 9} Ivanyi P....Franzke A. (2010)
5. Gene-specific signal joint modifications during V(D)J recombination of TCRAD locus genes in murine and human thymocytes. (PubMed id 17015149)^{1, 9} Touvrey C....Candeias S.M. (2006)
6. T-cell receptor alpha, beta, gamma, and delta chain gene microsatellites show no association with multiple sclerosis. (PubMed id 8857743)^{4, 9} Droogan A.G....Graham C.A. (1996)
7. Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ag eing. (PubMed id 23000520)¹ van der Weerd K....Staal F.J. (2013)
8. A GxxxG-like motif within HIV-1 fusion peptide is crit ical to its immunosuppressant activity, structure, and interaction with the tran smembrane domain of the T-cell receptor. (PubMed id 22872636)¹ Faingold O....Shai Y. (2012)
9. Minimal conformational plasticity enables TCR cross-re activity to different MHC class II heterodimers. (PubMed id 22953050)¹ Holland C.J....Cole D.K. (2012)
10. Effect of granulocyte colony-stimulating factor mobili zation on the expression patterns, clonality and signal transduction of TRAV and TRBV repertoire. (PubMed id 22658922)¹ Xuan L....Liu Q. (2012)

External Searches for TRA@ gene

Genome Databases showing TRA@ gene

Other Databases showing TRA@ gene

Specialized Databases showing TRA@ gene

Products
for TRA@ gene