TRA2B Gene
protein-coding GIFtS: 51
GCID: GC03M185632
|
|
transformer 2 beta homolog (Drosophila)(Previous names: splicing factor, arginine/serine-rich 10 (transformer 2...)
(Previous symbol: SFRS10)
| |
Aliases
for TRA2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transformer 2 Beta Homolog (Drosophila)1 2 | | TRA2-BETA2 | | SFRS101 2 3 | | TRAN2B2 | | Htra2-Beta1 | | Transformer-2 Protein Homolog Beta2 | | Splicing Factor, Arginine/Serine-Rich 10 (Transformer 2 Homolog, Drosophila)1 2 | | TRA2-Beta1 | | Transformer-2 Protein Homolog B2 3 | | HTRA2-Beta1 | | TRA-2 Beta2 3 | | Splicing Factor, Arginine/Serine-Rich 103 | | SRFS102 5 | | |
Export aliases for TRA2B gene to outside databasesPrevious GC identifers: GC03M187110 GC03M183042 |
Summaries
for TRA2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TRA2B:
This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays arole in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcriptvariants. (provided by RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: TRA2B_HUMAN, P62995Function: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can eitheractivate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motorneuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effectsof splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA
Gene Wiki entry for TRA2B
|
Genomic Views
for TRA2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TRA2B gene promoter:
HFH-3 p53 ATF-2 Bach2 CUTL1 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 FOXI1 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TRA2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRA2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q26.2-q27 Ensembl cytogenetic band: 3q27.2 HGNC cytogenetic band: 3q26.2-q27TRA2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M185632: view genomic region
(about GC identifiers)
Start:
|
185,632,356 bp from pter |
End:
|
185,655,924 bp from pter |
Size:
|
23,569 bases |
Orientation:
|
minus strand |
|
Proteins
for TRA2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRA2B_HUMAN, P62995 (See
protein sequence)Recommended Name: Transformer-2 protein homolog beta Size: 288 amino acids; 33666 Da
Subunit: Interacts with SAFB/SAFB1 (By similarity). Found in a pre-mRNA exonic splicing enhancer (ESE) complex withTRA2B/SFRS10, SNRNP70, SNRPA1 and SRRM1. Binds to A3 enhancer proteins SFRS4, SFRS5, SFRS6 and SFRS9. Interacts withCPSF6, RBMY1A1, RBMX, RNPS1 and phosphorylated SFRS13A
Subcellular location: Nucleus
4 PDB 3D structures from  and Proteopedia  for TRA2B:2CQC (3D)
2KXN (3D)
2RRA (3D)
2RRB (3D)
Secondary accessions: B4DVK2 D3DNU3 O15449 Q15815 Q64283Alternative splicing: 3 isoforms: P62995-1, Q15815-1 P62995-2, Q15815-2 P62995-3, Q15815-3 Explore the universe of human proteins at neXtProt for TRA2B: NX_P62995
Post-translational modifications:
Phosphorylated in the RS domains1
Dimethylation at Arg-241 is probably asymmetric1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P62995
TRA2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001230808.1 NP_004584.1
ENSEMBL proteins: ENSP00000416959 ENSP00000259043 ENSP00000406561 ENSP00000416887 ENSP00000371626 ENSP00000343857
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
TRA2B for ontologies About GeneDecksing
TRA2B Antibody Products:
Assay Products for TRA2B: |
Protein
Domains /
Families
for TRA2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TRA2B for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P62995ProtoNet protein and cluster: P62995 UniProtKB/Swiss-Prot: TRA2B_HUMAN, P62995Similarity: Belongs to the splicing factor SR familySimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for TRA2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TRA2B_HUMAN, P62995Function: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can eitheractivate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motorneuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effectsof splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TRA2B (NM_004593) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRA2B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRA2B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRA2B |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TRA2B for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Tra2btm1.2Bwir for TRA2B
6 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Tra2b):
TRA2B for phenotypes About GeneDecksing
|
Pathways & Interactions
for TRA2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for TRA2B
1 
Kegg Pathway (Kegg details for TRA2B):
TRA2B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRA2B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/67 Interacting proteins for TRA2B (P629952, 3 ENSP000004169594) via UniProtKB, MINT, STRING, and/or I2D (see all 67)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
TRA2B for ontologies About GeneDecksing
|
Drugs & Compounds
for TRA2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TRA2B
Search CenterWatch for drugs/clinical trials and news about TRA2B
|
Transcripts
for TRA2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TRA2B gene (2 alternative transcripts): NM_001243879.1 NM_004593.2 Unigene Cluster for TRA2B: Transformer 2 beta homolog (Drosophila) Hs.533122 [show with all ESTs]Unigene Representative Sequence: AB20920816 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000453386(uc010hym.3 uc003fpv.3) ENST00000492417 ENST00000463328(uc003fpt.3)
ENST00000259043 ENST00000414862 ENST00000487615(uc003fpu.3) ENST00000466832
ENST00000456380(uc003fpx.2) ENST00000382191 ENST00000465245 ENST00000485530
ENST00000493864 ENST00000477939 ENST00000471134 ENST00000480461 ENST00000342294
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TRA2B (NM_004593) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRA2B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRA2B |
Additional cDNA sequence: AB209208.1 AK091863.1 AK094495.1 AK098191.1 AK125610.1 AK301118.1 AK308267.1 AK315632.1 BC000160.2 BC000451.2 BC005898.1 CR749214.1 U61267.1 U68063.1 U87836.1 24/35 DOTS entries (see all 35): DT.91761815 DT.92360269 DT.100730598 DT.95233361 DT.100878524 DT.91761814 DT.100878535 DT.100878527 DT.97860426 DT.120855947 DT.91761807 DT.100878536 DT.120855962 DT.120855932 DT.75100088 DT.95310595 DT.120855981 DT.430536 DT.102833833 DT.120855959 DT.65287722 DT.91761809 DT.91761810 DT.100673868 24/562 AceView cDNA sequences (see all 562): CR608950 BQ224286 BU182464 CA446541 BQ006525 N67614 CA417647 AI676009 BU680707 BQ228617 BC005898 BE274831 AA767689 BU735882 BE614778 BF436526 AA344838 BQ189186 AA907446 AU119447 BQ892884 AA766721 CA391867 AI911213
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TRA2B (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | - | | | | - | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TRA2B
|
Expression
for TRA2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TRA2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGAACTGA
About this image
See TRA2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TRA2B
SOURCE GeneReport for Unigene cluster: Hs.533122
UniProtKB/Swiss-Prot: TRA2B_HUMAN, P62995Tissue specificity: Highest expression in heart, skeletal muscle and pancreas. Less abundant in kidney, placenta andbrain. Lowest expression in kidney and liver
SABiosciences Custom PCR Arrays for TRA2B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRA2B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRA2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRA2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRA2B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRA2B |
Orthologs
for TRA2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TRA2B gene from 8/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TRA2B1 |
transformer 2 beta homolog (Drosophila) |
83.91(n)
98.26(a) |
|
395403 NM_204678.1 NP_990009.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TRA2B6 |
-- |
93(a) |
1 ↔ 1 |
3(34294030-34307157) |
African clawed frog
(Xenopus laevis) |
Amphibia |
LOC3984482 |
similar to splicing factor, arginine/serine-rich (transformer more |
75.63(n) |
|
BC044695.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc566122 |
similar to splicing factor, arginine/serine-rich 1 more |
75.65(n) |
|
394172 BC049051.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
tra21 |
transformer 2 |
48.6(n)
51.1(a) |
|
36619 NM_206113.1 NP_995835.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
rsp-81 |
Protein RSP-8 |
48.03(n)
49.34(a) |
|
176613 NM_067132.4 NP_499533.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT4G357851 |
RNA-binding (RRM/RBD/RNP motifs) family protein |
42.53(n)
41.38(a) |
|
829732 NM_148402.5 NP_680768.5 |
rice
(Oryza sativa) |
Liliopsida |
Os08g03859001 |
hypothetical protein |
41.26(n)
42.74(a) |
|
4345455 NM_001068241.1 NP_001061706.1 |
ENSEMBL Gene Tree for TRA2B (if available)
TreeFam Gene Tree for TRA2B (if available) |
Paralogs
for TRA2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TRA2B gene
- RBMY1E2 RBMY1J2 RBMY1F2 RBMXL22 RBMXL32 RBMY1B2 RBMXL12 RBMY1A12
- CIRBP2 RBM32 TRA2A2 RBMX2 RBMY1D2
6 SIMAP similar genes for TRA2B using alignment to 3 protein entries: TRA2B_HUMAN (see all proteins):DKFZp686F18120 HSU53209 TRA2A RBMY1A1 CIRBP SRSF2
TRA2B for paralogs About GeneDecksing
|
Genomic Variants
for TRA2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TRA2B (185632356 - 185655924 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TRA2B: --
Human Gene Mutation Database (HGMD): TRA2B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRA2B |
|
Disorders
/ Diseases
for TRA2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TRA2B for disorders About GeneDecksing
OMIM gene information: 602719
OMIM disorders: --
15  diseases for TRA2B: About MalaCardsspinal muscular atrophy muscular atrophy frontotemporal dementia tauopathy
dementia endometrial cancer cervical cancer alzheimer's disease
cervicitis ovarian cancer breast cancer obesity
hypoxia malaria neuronitis
1 Novoseek disease relationship for TRA2B gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tauopathies |
68.6 |
1 |
12649279 (1) |
Human Genome Epidemiology (HuGE) Navigator: TRA2B (3 documents)
Export disorders for TRA2B gene to outside databases
|
Publications
for TRA2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TRA2B gene, integrated from 9 sources (see all 68):
(articles sorted by number of sources associating them with TRA2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human transformer-2-beta gene (SFRS10): complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform. (PubMed id 9790768)1, 2, 3, 9 Nayler O.... Stamm S. (1998)
- Human RNPS1 and its associated factors: a versatile alternative pre- mRNA splicing regulator in vivo. (PubMed id 14729963)1, 2, 9 Sakashita E.... Mayeda A. (2004)
- Molecular cloning of htra2-beta-1 and htra2-beta-2, two human homologs of tra-2 generated by alternative splicing. (PubMed id 9212162)1, 2, 9 Beil B.... Stamm S. (1997)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. (PubMed id 15169763)1, 2 Dettwiler S.... Barabino S.M. (2004)
- Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. (PubMed id 15009664)1, 2 Wang J....Andreadis A. (2004)
- Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. (PubMed id 14765198)1, 2 Shin C.... Manley J.L. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding. (PubMed id 12761049)1, 2 Nasim M.T....Eperon I.C. (2003)
|
External Searches for TRA2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TRA2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TRA2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TRA2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TRA2B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TRA2B gene:
Search GeneIP for patents involving TRA2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for TRA2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TRA2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRA2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRA2B | | | OriGene Protein Over-expression Lysate for TRA2B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TRA2B | | OriGene 3'-UTR Clone for TRA2B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRA2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TRA2B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TRA2B | | OriGene Custom Protein Services for TRA2B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRA2B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRA2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRA2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRA2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRA2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRA2B |
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| | | | Search Tocris compounds for TRA2B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRA2B |
|  |  |  | | | | Search ThermoFisher Antibodies for TRA2B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRA2B |
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