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Aliases for TPTEP1 Gene

Aliases for TPTEP1 Gene

  • Transmembrane Phosphatase With Tensin Homology Pseudogene 1 2 3 5
  • Endogenous Retroviral Protease Pseudogene 3
  • TPTE Pseudogene 3
  • PsiTPTE22 3

External Ids for TPTEP1 Gene

Previous GeneCards Identifiers for TPTEP1 Gene

  • GC22P017085

Summaries for TPTEP1 Gene

GeneCards Summary for TPTEP1 Gene

TPTEP1 (Transmembrane Phosphatase With Tensin Homology Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPTEP1 Gene

Genomics for TPTEP1 Gene

Regulatory Elements for TPTEP1 Gene

Enhancers for TPTEP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F016600 1.1 ENCODE 10.1 +0.9 911 4.4 HDGF PKNOX1 ARNT CREB3L1 SIN3A DMAP1 FEZF1 ZNF2 YY1 ZNF143 TPTEP1 ENSG00000283633 ENSG00000267338
GH22F017562 1.5 FANTOM5 Ensembl ENCODE 5.8 +961.5 961452 2.3 ARID4B DMAP1 ZNF48 ZSCAN9 RAD21 RARA YY1 CREM CEBPB PPARG SLC25A18 TPTEP1 BID MICAL3 CECR6 LOC105372850
GH22F016721 0.7 FANTOM5 Ensembl 7.9 +120.7 120714 2.0 HDAC1 ZBTB17 TPTEP1 XKR3 CECR1 IL17RA VWFP1 PIR52821
GH22F017594 1.3 Ensembl ENCODE 4.2 +993.2 993201 1.4 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 ATP6V1E1 TPTEP1 LOC101929372 PIR61133
GH22F017528 1.1 Ensembl ENCODE 4.5 +927.2 927196 0.8 ELF3 ATF1 SAP130 ZMYM3 ZNF48 ZBTB40 NR2F6 CREM ZNF652 GATAD2A SLC25A18 TPTEP1 DNAJA1P6 PIR55461
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TPTEP1 on UCSC Golden Path with GeneCards custom track

Promoters for TPTEP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000290892 613 4201 HDGF PKNOX1 ARNT CREB3L1 SIN3A DMAP1 FEZF1 ZNF2 YY1 ZNF143

Genomic Location for TPTEP1 Gene

Chromosome:
22
Start:
16,601,887 bp from pter
End:
16,698,742 bp from pter
Size:
96,856 bases
Orientation:
Plus strand

Genomic View for TPTEP1 Gene

Genes around TPTEP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPTEP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPTEP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPTEP1 Gene

Proteins for TPTEP1 Gene

Post-translational modifications for TPTEP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TPTEP1 Gene

Domains & Families for TPTEP1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TPTEP1 Gene

Function for TPTEP1 Gene

Phenotypes for TPTEP1 Gene

GenomeRNAi human phenotypes for TPTEP1:
genes like me logo Genes that share phenotypes with TPTEP1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TPTEP1 Gene

Localization for TPTEP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TPTEP1 Gene

Pathways & Interactions for TPTEP1 Gene

SuperPathways for TPTEP1 Gene

No Data Available

Interacting Proteins for TPTEP1 Gene

Gene Ontology (GO) - Biological Process for TPTEP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TPTEP1 Gene

Transcripts for TPTEP1 Gene

Unigene Clusters for TPTEP1 Gene

Transmembrane phosphatase with tensin homology pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TPTEP1 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18a · 18b · 18c ^
SP1:
SP2: - - -
SP3:
SP4: - - -
SP5: -
SP6:
SP7: - -
SP8:
SP9:
SP10:
SP11:

ExUns: 19a · 19b · 19c ^ 20a · 20b ^ 21 ^ 22
SP1:
SP2:
SP3:
SP4:
SP5:
SP6: - -
SP7:
SP8: -
SP9: - - -
SP10:
SP11:

Relevant External Links for TPTEP1 Gene

GeneLoc Exon Structure for
TPTEP1
ECgene alternative splicing isoforms for
TPTEP1

Expression for TPTEP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TPTEP1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TPTEP1 Gene:

TPTEP1

SOURCE GeneReport for Unigene cluster for TPTEP1 Gene:

Hs.474116
genes like me logo Genes that share expression patterns with TPTEP1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TPTEP1 Gene

Orthologs for TPTEP1 Gene

Evolution for TPTEP1 Gene

ENSEMBL:
Gene Tree for TPTEP1 (if available)
TreeFam:
Gene Tree for TPTEP1 (if available)

No data available for Orthologs for TPTEP1 Gene

Paralogs for TPTEP1 Gene

No data available for Paralogs for TPTEP1 Gene

Variants for TPTEP1 Gene

Sequence variations from dbSNP and Humsavar for TPTEP1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs10320664 -- 16,644,545(+) tctta(G/T)aatat intron-variant
rs10427681 -- 16,638,560(+) TATTT(A/G)TTTGT intron-variant
rs10433291 -- 16,633,888(+) ttctt(A/C)atcca intron-variant
rs10433292 -- 16,633,915(+) cattt(G/T)ggttg intron-variant
rs10433293 -- 16,633,945(+) gtgaa(C/T)agtgc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TPTEP1 Gene

Variant ID Type Subtype PubMed ID
nsv979625 CNV duplication 23825009
nsv966062 CNV duplication 23825009
nsv964574 CNV duplication 23825009
nsv964573 CNV duplication 23825009
nsv953679 CNV deletion 24416366
nsv588071 CNV gain 21841781
nsv588062 CNV gain 21841781
nsv527637 CNV gain 19592680
nsv517059 CNV gain+loss 19592680
nsv471178 CNV gain 18288195
nsv1139042 CNV deletion 24896259
nsv1071773 CNV deletion 25765185
nsv1063326 CNV loss 25217958
nsv1056300 CNV loss 25217958
esv3893423 CNV gain 25118596
esv3647195 CNV loss 21293372
esv3584481 CNV gain 24956385
esv3584480 CNV gain 24956385
esv3575407 CNV gain 25503493
esv3575406 CNV gain 25503493
esv3575399 CNV gain 25503493
esv2763696 CNV gain 21179565
esv2723932 CNV deletion 23290073
esv2671417 CNV deletion 23128226
esv26428 CNV loss 19812545
dgv819e214 CNV gain 21293372
dgv7946n54 CNV gain 21841781
dgv7943n54 CNV gain 21841781
dgv723n67 CNV gain 20364138
dgv540n27 CNV gain 19166990
dgv539n27 CNV gain 19166990
dgv4462n100 CNV gain 25217958
dgv4461n100 CNV loss 25217958
dgv4460n100 CNV gain 25217958
dgv4459n100 CNV gain 25217958
dgv4458n100 CNV gain 25217958
dgv18e196 CNV duplication 17116639
dgv1276e212 CNV gain 25503493

Relevant External Links for TPTEP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TPTEP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TPTEP1 Gene

Disorders for TPTEP1 Gene

Relevant External Links for TPTEP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TPTEP1

No disorders were found for TPTEP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPTEP1 Gene

Publications for TPTEP1 Gene

  1. The TPTE gene family: cellular expression, subcellular localization and alternative splicing. (PMID: 14659893) Tapparel C. … Antonarakis S.E. (Gene 2003) 2 3 64
  2. The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers. (PMID: 20112338) Liang Q. … Zheng S. (Int. J. Cancer 2010) 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  5. Members of the RTVL-H family of human endogenous retrovirus-like elements are expressed in placenta. (PMID: 2551777) Johansen T. … Bjorklid E. (Gene 1989) 3 64

Products for TPTEP1 Gene

Sources for TPTEP1 Gene

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