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Aliases for TPTE2P1 Gene

Aliases for TPTE2P1 Gene

  • Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1 2 3 5

External Ids for TPTE2P1 Gene

Previous GeneCards Identifiers for TPTE2P1 Gene

  • GC00U922913
  • GC13M025499
  • GC13M006316

Summaries for TPTE2P1 Gene

GeneCards Summary for TPTE2P1 Gene

TPTE2P1 (Transmembrane Phosphoinositide 3-Phosphatase And Tensin Homolog 2 Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPTE2P1 Gene

Genomics for TPTE2P1 Gene

Regulatory Elements for TPTE2P1 Gene

Enhancers for TPTE2P1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G025195 0.8 dbSUPER 13.6 -229.3 -229276 5.1 ZNF146 ESRRA ZFP64 FEZF1 ZIC2 ZNF697 FOS FOSL2 ZNF433 RFX1 TPTE2P1 ATP8A2 PIR45438 RPL23AP69
GH13G024922 1.1 ENCODE 9.1 +45.4 45351 2.6 HDGF PKNOX1 CREB3L1 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF766 TPTE2P1 CENPJ RNF17 ENSG00000273628
GH13G025214 0.8 ENCODE dbSUPER 10.2 -246.3 -246267 1.3 CTCF SIN3A MNT FOS ZNF248 LINC01053 LINC00463 TPTE2P1 MTMR6 LINC01076 LOC105370121
GH13G025152 0.5 dbSUPER 13.5 -184.4 -184363 0.5 ZNF157 KLF4 FOXA1 TPTE2P1 LINC00463 LINC01053 ENSG00000279695 AMER2
GH13G024921 0.5 Ensembl 9.9 +47.4 47387 0.2 POLR2H IKZF1 CEBPG RBFOX2 TPTE2P1 CENPJ GC13P024788 PIR31198
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TPTE2P1 on UCSC Golden Path with GeneCards custom track

Promoters for TPTE2P1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000060117 186 600 CTCF ZNF654 REST RAD21 FOXA1 FOSL1 ZSCAN21 IKZF1 KLF9 ZNF143

Genomic Location for TPTE2P1 Gene

Chromosome:
13
Start:
24,924,677 bp from pter
End:
24,968,487 bp from pter
Size:
43,811 bases
Orientation:
Minus strand

Genomic View for TPTE2P1 Gene

Genes around TPTE2P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPTE2P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPTE2P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPTE2P1 Gene

Proteins for TPTE2P1 Gene

  • Protein details for TPTE2P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T6R2-TPT2L_HUMAN
    Recommended name:
    Putative phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2P1
    Protein Accession:
    Q5T6R2
    Secondary Accessions:
    • B3KST4
    • B4DMH9

    Protein attributes for TPTE2P1 Gene

    Size:
    138 amino acids
    Molecular mass:
    15541 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TPTE2P1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TPTE2P1 Gene

Post-translational modifications for TPTE2P1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TPTE2P1 Gene

Domains & Families for TPTE2P1 Gene

Protein Domains for TPTE2P1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TPTE2P1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TPTE2P1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TPTE2P1 Gene

Function for TPTE2P1 Gene

Phenotypes for TPTE2P1 Gene

GenomeRNAi human phenotypes for TPTE2P1:
genes like me logo Genes that share phenotypes with TPTE2P1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TPTE2P1 Gene

Localization for TPTE2P1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TPTE2P1 Gene

Pathways & Interactions for TPTE2P1 Gene

SuperPathways for TPTE2P1 Gene

No Data Available

Interacting Proteins for TPTE2P1 Gene

Gene Ontology (GO) - Biological Process for TPTE2P1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TPTE2P1 Gene

Drugs & Compounds for TPTE2P1 Gene

No Compound Related Data Available

Transcripts for TPTE2P1 Gene

mRNA/cDNA for TPTE2P1 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TPTE2P1 Gene

Transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TPTE2P1 Gene

No ASD Table

Relevant External Links for TPTE2P1 Gene

GeneLoc Exon Structure for
TPTE2P1
ECgene alternative splicing isoforms for
TPTE2P1

Expression for TPTE2P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TPTE2P1 Gene

mRNA differential expression in normal tissues according to GTEx for TPTE2P1 Gene

This gene is overexpressed in Thyroid (x5.7), Brain - Cerebellar Hemisphere (x5.5), and Brain - Cerebellum (x5.0).

Protein differential expression in normal tissues from HIPED for TPTE2P1 Gene

This gene is overexpressed in Heart (47.6) and Pancreatic juice (21.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TPTE2P1 Gene



Protein tissue co-expression partners for TPTE2P1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TPTE2P1 Gene:

TPTE2P1

SOURCE GeneReport for Unigene cluster for TPTE2P1 Gene:

Hs.620592
genes like me logo Genes that share expression patterns with TPTE2P1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TPTE2P1 Gene

Orthologs for TPTE2P1 Gene

Evolution for TPTE2P1 Gene

ENSEMBL:
Gene Tree for TPTE2P1 (if available)
TreeFam:
Gene Tree for TPTE2P1 (if available)

No data available for Orthologs for TPTE2P1 Gene

Paralogs for TPTE2P1 Gene

(4) SIMAP similar genes for TPTE2P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TPTE2P1: view

No data available for Paralogs for TPTE2P1 Gene

Variants for TPTE2P1 Gene

Sequence variations from dbSNP and Humsavar for TPTE2P1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000098322 -- 24,970,144(+) TCCAC(A/G)AAACC upstream-variant-2KB
rs1000212064 -- 24,963,737(+) TGAAA(C/T)GTTTA intron-variant
rs1000238682 -- 24,941,088(+) GGGAA(G/T)TTCAT intron-variant
rs1000420894 -- 24,957,772(+) CATTG(C/T)GAGGC intron-variant
rs1000667054 -- 24,963,990(+) AGAGT(A/T)CTTAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TPTE2P1 Gene

Variant ID Type Subtype PubMed ID
dgv537e212 CNV loss 25503493
esv28932 CNV loss 19812545
esv3362432 CNV insertion 20981092
nsv1041986 CNV gain 25217958
nsv1116459 OTHER inversion 24896259
nsv1153497 OTHER inversion 26484159
nsv1160094 CNV deletion 26073780
nsv442664 CNV loss 18776908
nsv964 CNV deletion 18451855
nsv977219 CNV duplication 23825009

Relevant External Links for TPTE2P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TPTE2P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TPTE2P1 Gene

Disorders for TPTE2P1 Gene

Relevant External Links for TPTE2P1

Genetic Association Database (GAD)
TPTE2P1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TPTE2P1

No disorders were found for TPTE2P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPTE2P1 Gene

Publications for TPTE2P1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3 64
  3. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 4 64

Products for TPTE2P1 Gene

Sources for TPTE2P1 Gene

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