TPSB2 Gene
protein-coding GIFtS: 55
GCID: GC16M001281
|
|
tryptase beta 2 (gene/pseudogene)(Previous name: tryptase beta 2 )
| |
Aliases
for TPSB2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tryptase Beta 2 (Gene/Pseudogene)1 2 | | Tryptase Beta-22 | | TPS22 3 5 | | TryptaseB1 | | EC 3.4.21.593 8 | | TryptaseC1 | | Tryptase Beta 21 | | Tryptase-23 | | Mast Cell Tryptase Beta II2 | | Tryptase II3 | | Mast Cell Tryptase Beta III2 | | EC 3.4.218 |
Export aliases for TPSB2 gene to outside databasesPrevious GC identifers: GC16U990168 GC16P001231 GC16P001191 GC16P001234 GC16M001219 GC16M001278 GC16M001279 GC16M001280 |
Summaries
for TPSB2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TPSB2:
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymaticallyactive only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors.Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinctfeatures. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which arethought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of theinitiator Met codon, which separates the site of transcription initiation from protein coding sequence. This featureis characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount ofsequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III.Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptasespredominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic andinflammatory disorders. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TRYB2_HUMAN, P20231Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupledactivation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Requiredto efficiently combat K.pneumoniae infection (By similarity)
Gene Wiki entry for TPSB2
|
Genomic Views
for TPSB2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TPSB2 gene promoter:
AhR Pax-5 HNF-1 ATF-2 HNF-1A
Other transcription factors
Search SABiosciences Chromatin IP Primers for TPSB2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPSB2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3TPSB2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M001281: view genomic region
(about GC identifiers)
Start:
|
1,277,272 bp from pter |
End:
|
1,280,214 bp from pter |
Size:
|
2,943 bases |
Orientation:
|
minus strand |
|
Proteins
for TPSB2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRYB2_HUMAN, P20231 (See
protein sequence)Recommended Name: Tryptase beta-2 precursor Size: 275 amino acids; 30515 Da
Subunit: Homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence ofheparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When theconcentration of active monomers is higher, they convert to active monomers and then to active tetramers. Thesemonomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites inthe tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitorseg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms acomplex with SERPINB6
Subcellular location: Secreted. Note=Released from the secretory granules upon mast cell activation
6/11 PDB 3D structures from  and Proteopedia  for TPSB2 (see all 11):1A0L (3D)
1AAO (3D)
2BM2 (3D)
2FPZ (3D)
2FS8 (3D)
2FS9 (3D)
Secondary accessions: D2E6S0 D2E6S2 O95827 Q15664 Q9UQI6 Q9UQI7Explore the universe of human proteins at neXtProt for TPSB2: NX_P20231
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P20231
4/18 DME Specific Peptides for TPSB2 (P20231) (see all 18)
TPSB2 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_077078.5
ENSEMBL proteins: ENSP00000426256 ENSP00000412409
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
NAS | -- |
TPSB2 for ontologies About GeneDecksing
TPSB2 Antibody Products:
Assay Products for TPSB2: |
Protein
Domains /
Families
for TPSB2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TPSB2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P20231ProtoNet protein and cluster: P20231 2 Blocks protein families: IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature
UniProtKB/Swiss-Prot: TRYB2_HUMAN, P20231Similarity: Belongs to the peptidase S1 family. Tryptase subfamilySimilarity: Contains 1 peptidase S1 domain |
Function
for TPSB2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TRYB2_HUMAN, P20231Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupledactivation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Requiredto efficiently combat K.pneumoniae infection (By similarity)Catalytic activity: Preferential cleavage: Arg- -Xaa, Lys- -Xaa, but with more restricted specificity than trypsinEnzyme Numbers (IUBMB): EC 3.4.21.591 2 EC 3.4.212
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TPSB2 (NM_024164) | |  | Sino Biological Human cDNA Clone for TPSB2 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPSB2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSB2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPSB2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
TPSB2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Tpsb2tm1Dle for TPSB2
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Tpsb2):
TPSB2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TPSB2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TPSB2
3 Interacting proteins for TPSB2 (P202313) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
NAS | -- |
TPSB2 for ontologies About GeneDecksing
|
Drugs & Compounds
for TPSB2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TPSB2 for compounds About GeneDecksing
 Compounds for TPSB2 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| APC 366 | Tryptase inhibitor | [178925-65-0] |
2 HMDB Compounds for TPSB2 About this table
4 DrugBank Compounds for TPSB2 About this table
1 Novoseek chemical compound relationship for TPSB2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| serine |
49.8 |
2 |
8039831 (1), 18039527 (1) |
Search CenterWatch for drugs/clinical trials and news about TPSB2 / TRYB2
|
Transcripts
for TPSB2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TPSB2 gene: NM_024164.5 Unigene Cluster for TPSB2: Tryptase beta 2 (gene/pseudogene) Hs.592982 [show with all ESTs]Unigene Representative Sequence: BC0659233 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000339687(uc010brk.1) ENST00000445910 ENST00000430512(uc002ckx.3 uc002cky.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TPSB2 (NM_024164) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPSB2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSB2 |
Additional cDNA sequence: AK308208.1 BC029356.1 BC065923.1 FJ931119.1 FJ931120.1 M33492.1 M37488.1 S55551.1 3 DOTS entries: DT.446428 DT.100749578 DT.75138719 24/82 AceView cDNA sequences (see all 82): AA887888 AI581938 BV200561 CA867461 BU787858 BQ003361 BQ082929 BV207482 BV185679 BV207480 BM663927 BQ719498 BM991728 BV207479 CD672689 BC074974 BV201257 BI819421 BV200560 BM989945 AI610847 BF876081 M33493 AI832733
GeneLoc Exon Structure
|
Expression
for TPSB2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TPSB2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for TPSB2
SOURCE GeneReport for Unigene cluster: Hs.592982
SABiosciences Custom PCR Arrays for TPSB2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPSB2
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TPSB2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPSB2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPSB2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPSB2 |
Orthologs
for TPSB2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for TPSB2 (if available)
TreeFam Gene Tree for TPSB2 (if available) |
Paralogs
for TPSB2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TPSB2 gene
- TPSAB1
18/107 SIMAP similar genes for TPSB2 using alignment to 4 protein entries: TRYB2_HUMAN (see all proteins)
(see all similar genes):tryptaseB tryptaseC TPSAB1 TPSD1 MGC52282 F12
TPSG1 PRSS29P PRSS22 DKFZp586F0824 PRSS27 PRSS45
CELA3A CELA2A F2 PRSS36 PRSS42 ELA2A
TPSB2 for paralogs About GeneDecksing
|
Genomic Variants
for TPSB2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: TRYB2_HUMAN, P20231Polymorphism: There are two alleles; beta-II and beta-III. Beta-II is the most commun allele. There are two forms ofthe beta-III allele, a short and a long form. The short form (also named frameshifted form) is carried by 23% and 19%of individuals of European and African ancestry but 0% of Asian subjects. In the human genome reference versionGRCh37/hg19, the allele beta-III short form is represented
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TPSB2 (1277272 - 1280214 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for TPSB2
5 CNVs: 72416 29991 4915 5329 29995
1 Inversion: 37173
Human Gene Mutation Database (HGMD): TPSB2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPSB2 |
|
Disorders
/ Diseases
for TPSB2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TPSB2 for disorders About GeneDecksing
OMIM gene information: 191081
OMIM disorders: --
3  diseases for TPSB2: About MalaCardsasthma mastocytosis pneumonia
1 disease from the University of Copenhagen DISEASES database for TPSB2:Dermatitis herpetiformis Human Genome Epidemiology (HuGE) Navigator: TPSB2 (1 document)
Export disorders for TPSB2 gene to outside databases
|
Publications
for TPSB2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TPSB2 gene, integrated from 9 sources (see all 30):
(articles sorted by number of sources associating them with TPSB2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. (PubMed id 19748655)1, 2, 3 Trivedi N.N....Caughey G.H. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3. (PubMed id 9920877)1, 2 Pallaoro M....Caughey G.H. (1999)
- The structure of the human betaII-tryptase tetramer: fo(u)r better or worse. (PubMed id 10500112)1, 2 Sommerhoff C.P.... Bergner A. (1999)
- Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. (PubMed id 9521329)1, 2 Pereira P.J.B.... Bode W. (1998)
- Characterization of a tryptase mRNA expressed in the human basophil cell line KU812. (PubMed id 8434231)1, 2 Blom T. and Hellman L. (1993)
- Cloning and characterization of a second complementary DNA for human tryptase. (PubMed id 2203827)1, 2 Miller J.S.... Schwartz L.B. (1990)
- Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family. (PubMed id 2187193)1, 2 Vanderslice P....Caughey G.H. (1990)
- Active monomers of human beta-tryptase have expanded substrate specificities. (PubMed id 18039527)2, 9 Fukuoka Y. and Schwartz L.B. (2007)
- Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog. (PubMed id 10898108)1, 9 Guida M.... Hall J. (2000)
|
External Searches for TPSB2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TPSB2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TPSB2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TPSB2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TPSB2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TPSB2 gene:
Search GeneIP for patents involving TPSB2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TPSB2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TPSB2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPSB2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPSB2 | | | OriGene Protein Over-expression Lysate for TPSB2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TPSB2 | | OriGene 3'-UTR Clone for TPSB2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSB2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TPSB2 | | OriGene Custom Protein Services for TPSB2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TPSB2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPSB2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPSB2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPSB2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPSB2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPSB2 |
| |
 |  |  |  | |
| | | | Tocris compounds for TPSB2 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPSB2 |
|  |  |  | | | | Search ThermoFisher Antibodies for TPSB2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSB2 |
|
|
|
|
