TPSAB1 Gene
protein-coding GIFtS: 60
GCID: GC16P001290
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|
tryptase alpha/beta 1(Previous name: tryptase beta 1 )
(Previous symbols: TPSB1, TPS1, TPS2)
| |
Aliases
for TPSAB1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tryptase Alpha/Beta 11 2 | | Tryptase Alpha II2 | | TPS11 2 3 5 | | Tryptase Alpha/Beta-12 | | TPS21 2 3 | | Tryptase Beta I2 | | TPSB11 2 3 | | Tryptase Beta-12 | | Tryptase Beta 11 2 | | Tryptase-13 | | Tryptase Alpha-12 3 | | Tryptase-I1 | | Tryptase I2 3 | | Tryptase-III1 | | EC 3.4.21.593 8 | | Tryptase-13 | | Mast Cell Alpha II Tryptase2 | | EC 3.4.218 | | Mast Cell Beta I Tryptase2 | | |
Export aliases for TPSAB1 gene to outside databasesPrevious GC identifer: GC16P001233 |
Summaries
for TPSAB1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TPSAB1:
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymaticallyactive only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors.Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinctfeatures. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which arethought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of theinitiator Met codon, which separates the site of transcription initiation from protein coding sequence. This featureis characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount ofsequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Betatryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate.Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatorydisorders. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TRYB1_HUMAN, Q15661Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupledactivation-degranulation response of this cell type (By similarity)
Gene Wiki entry for TPSAB1
|
Genomic Views
for TPSAB1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TPSAB1 gene promoter:
AhR Pax-5 HNF-1 ATF-2 HNF-1A
Other transcription factors
Search SABiosciences Chromatin IP Primers for TPSAB1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPSAB1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3TPSAB1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P001290: view genomic region
(about GC identifiers)
Start:
|
1,290,678 bp from pter |
End:
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1,293,619 bp from pter |
Size:
|
2,942 bases |
Orientation:
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plus strand |
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Proteins
for TPSAB1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TRYB1_HUMAN, Q15661 (See
protein sequence)Recommended Name: Tryptase alpha/beta-1 precursor Size: 275 amino acids; 30515 Da
Subunit: Homotetramer. The active tetramer is converted to inactive monomers at neutral and acidic pH in the absence ofheparin. Low concentrations of inactive monomers become active monomers at pH 6.0 in the presence of heparin. When theconcentration of active monomers is higher, they convert to active monomers and then to active tetramers. Thesemonomers are active and functionally distinct from the tetrameric enzyme. In contrast to the hidden active sites inthe tetrameric form, the active site of the monomeric form is accessible for macromolecular proteins and inhibitorseg: fibrinogen which is a substrate for the monomeric but not for the tetrameric form. The monomeric form forms acomplex with SERPINB6
Subcellular location: Secreted. Note=Released from the secretory granules upon mast cell activation (By similarity)
6/7 PDB 3D structures from  and Proteopedia  for TPSAB1 (see all 7):1LTO (3D)
2F9N (3D)
2F9O (3D)
2F9P (3D)
2ZEB (3D)
2ZEC (3D)
Secondary accessions: D2E6R9 D2E6S1 P15157 Q15663 Q6B052 Q9H2Y4 Q9H2Y5 Q9UQI1Alternative splicing: 2 isoforms: Q15661-1 Q15661-2 Explore the universe of human proteins at neXtProt for TPSAB1: NX_Q15661
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15661
4/18 DME Specific Peptides for TPSAB1 (Q15661) (see all 18)
TPSAB1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003285.2
ENSEMBL proteins: ENSP00000343577 ENSP00000454427 ENSP00000418247 ENSP00000456821 Reactome Protein details: Q15661
Human Recombinant Protein Products for TPSAB1:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
TAS | -- | | GO:0005615 | extracellular space |
IDA | -- | | GO:0031012 | colocalizes with extracellular matrix |
IDA | -- |
TPSAB1 for ontologies About GeneDecksing
TPSAB1 Antibody Products:
Assay Products for TPSAB1: |
Protein
Domains /
Families
for TPSAB1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TPSAB1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15661ProtoNet protein and cluster: Q15661 2 Blocks protein families: IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature
UniProtKB/Swiss-Prot: TRYB1_HUMAN, Q15661Similarity: Belongs to the peptidase S1 family. Tryptase subfamilySimilarity: Contains 1 peptidase S1 domain |
Function
for TPSAB1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TRYB1_HUMAN, Q15661Function: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupledactivation-degranulation response of this cell type (By similarity)Catalytic activity: Preferential cleavage: Arg- -Xaa, Lys- -Xaa, but with more restricted specificity than trypsin Enzyme Numbers (IUBMB): EC 3.4.21.591 2 EC 3.4.212
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TPSAB1 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for TPSAB1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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Synthesis Service for TPSAB1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSAB1 |
|
Pathways & Interactions
for TPSAB1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Degradation of the extracellular matrix | | | 2 | Collagen formation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for TPSAB1
TPSAB1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TPSAB1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
4 Interacting proteins for TPSAB1 (Q156611, 3 ENSP000003435774) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
TPSAB1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TPSAB1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TPSAB1 for compounds About GeneDecksing
 Compounds for TPSAB1 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| APC 366 | Tryptase inhibitor | [178925-65-0] |
2 HMDB Compounds for TPSAB1 About this table
2 DrugBank Compounds for TPSAB1 About this table
6 Novoseek chemical compound relationships for TPSAB1 gene About this table
Search CenterWatch for drugs/clinical trials and news about TPSAB1 / TRYB1
|
Transcripts
for TPSAB1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TPSAB1 gene: NM_003294.3 Unigene Cluster for TPSAB1: Tryptase alpha/beta 1 Hs.405479 [show with all ESTs]Unigene Representative Sequence: BC0384165 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000338844(uc002ckz.3 uc010uux.2) ENST00000562675 ENST00000461509
ENST00000562432 ENST00000561736
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TPSAB1 (NM_003294) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPSAB1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSAB1 |
Additional cDNA sequence: AF206665.1 AF206666.1 AF206667.1 BC028059.1 BC038416.1 BC051852.1 BC074974.2 BC074975.2 CR541836.1 FJ931118.1 M30038.1 M33491.1 M33493.1 5 DOTS entries: DT.75138719 DT.446428 DT.100749578 DT.98131726 DT.95273039 24/124 AceView cDNA sequences (see all 124): M33491 NM_012217 NM_003294 AI799627 AF206664 BM708916 BU787497 CD672689 CR541836 BV183385 BV200561 BV207482 BQ721078 CA867461 NM_024164 CA439686 BV183386 BU787772 CD671891 BC038416 AF421357 CA425354 BC074974 BC065923
GeneLoc Exon Structure
|
Expression
for TPSAB1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TPSAB1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAATCAAAA
About this image
See TPSAB1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TPSAB1
SOURCE GeneReport for Unigene cluster: Hs.405479
SABiosciences Expression via Pathway-Focused PCR Arrays including TPSAB1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPSAB1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TPSAB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPSAB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPSAB1 |
Orthologs
for TPSAB1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TPSAB1 gene from 1/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG16326 |
-- |
5(a) |
possible ortholog |
X(8146705-8166495) |
ENSEMBL Gene Tree for TPSAB1 (if available)
TreeFam Gene Tree for TPSAB1 (if available) |
Paralogs
for TPSAB1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TPSAB1 gene
- TPSB2 PRSS462 PRSS552 PRSS482 PRSS222 PRSS272 PRSS212 PRSS452
- TPSG12 TPSD12 PRSS382 PRSS532 PRSS502 PRSS422 PRSS362 PRSS332
- KLKB12 PRSS82 F112 OVCH12
18/105 SIMAP similar genes for TPSAB1 using alignment to 6 protein entries: TRYB1_HUMAN (see all proteins)
(see all similar genes):TPSB2 tryptaseB tryptaseC TPSD1 FAM175A MGC52282
PRSS29P TPSG1 PRSS22 PRSS45 PRSS27 CELA2B
CELA3A F12 DKFZp586F0824 F2 CELA2A ELA2A
TPSAB1 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for TPSAB1
PGOHUM00000262265 PGOHUM00000262266 PGOHUM00000248694 PGOHUM00000262267 PGOHUM00000259804
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Genomic Variants
for TPSAB1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: TRYB1_HUMAN, Q15661Polymorphism: There are two alleles alpha and beta-I. The sequence shown is that of allele beta-I
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TPSAB1 (1290678 - 1293619 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for TPSAB1
5 CNVs: 72416 29991 4915 5329 29995
2 Inversions: 37173 37174 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPSAB1 |
|
Disorders
/ Diseases
for TPSAB1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TPSAB1 for disorders About GeneDecksing
OMIM gene information: 191080
OMIM disorders: --
20/23  diseases for TPSAB1 (see all 23): About MalaCardssudden infant death syndrome candida glabrata asthma mastocytosis
cutaneous mastocytosis systemic mastocytosis amebiasis myeloid leukemia
aortic aneurysm chronic myeloid leukemia acute myeloid leukemia pterygium
urticaria rheumatoid arthritis multiple sclerosis diarrhea
fibrosarcoma leukemia arthritis osteoarthritis
3 Novoseek disease relationships for TPSAB1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: TPSAB1 (2 documents)
Export disorders for TPSAB1 gene to outside databases
|
Publications
for TPSAB1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TPSAB1 gene, integrated from 9 sources (see all 98):
(articles sorted by number of sources associating them with TPSAB1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3. (PubMed id 9920877)1, 2, 3 Pallaoro M....Caughey G.H. (1999)
- Characterization of two highly polymorphic human tryptase loci and comparison with a newly discovered monkey tryptase ortholog. (PubMed id 10898108)1, 2, 9 Guida M.... Hall J. (2000)
- Cloning and characterization of a second complementary DNA for human tryptase. (PubMed id 2203827)1, 3, 9 Miller J.S.... Schwartz L.B. (1990)
- Human subjects are protected from mast cell tryptase deficiency despite frequent inheritance of loss-of-function mutations. (PubMed id 19748655)1, 2 Trivedi N.N....Caughey G.H. (2009)
- Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family. (PubMed id 2187193)1, 2 Vanderslice P....Caughey G.H. (1990)
- Cloning and characterization of complementary DNA for human tryptase. (PubMed id 2677049)1, 2 Miller J.S.... Schwartz L.B. (1989)
- Human tryptases alpha and beta/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft. (PubMed id 10391906)1, 9 Huang C....Stevens R.L. (1999)
- Novel partners of SPAG11B isoform D in the human male reproductive tract. (PubMed id 19535787)1, 9 Radhakrishnan Y....French F.S. (2009)
- X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition. (PubMed id 16414069)1, 9 Rohr K.B....Than M.E. (2006)
- The crystal structure of human alpha1-tryptase reveals a blocked substrate-binding region. (PubMed id 12162961)2, 9 Marquardt U....Sommerhoff C. (2002)
|
External Searches for TPSAB1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TPSAB1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TPSAB1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TPSAB1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TPSAB1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TPSAB1 gene:
Search GeneIP for patents involving TPSAB1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TPSAB1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TPSAB1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPSAB1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TPSAB1 | | | OriGene Protein Over-expression Lysate for TPSAB1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TPSAB1 | | OriGene 3'-UTR Clone for TPSAB1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPSAB1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TPSAB1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPSAB1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPSAB1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPSAB1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPSAB1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPSAB1 |
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| | | |  |  |  |  | | | | | | Recombinant Protein for TPSAB1 |
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 | | | | |  |  |  |  | | | | ThermoFisher Antibodies for TPSAB1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPSAB1 |
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