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Aliases for TPRXL Gene

Aliases for TPRXL Gene

  • Tetra-Peptide Repeat Homeobox-Like 2 3 5

External Ids for TPRXL Gene

Previous GeneCards Identifiers for TPRXL Gene

  • GC03P013954
  • GC03P013978
  • GC03P013912

Summaries for TPRXL Gene

Entrez Gene Summary for TPRXL Gene

  • Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the TPRX homeobox gene family. [provided by RefSeq, Jul 2008]

GeneCards Summary for TPRXL Gene

TPRXL (Tetra-Peptide Repeat Homeobox-Like) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPRXL Gene

Genomics for TPRXL Gene

Regulatory Elements for TPRXL Gene

Enhancers for TPRXL Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TPRXL on UCSC Golden Path with GeneCards custom track

Genomic Location for TPRXL Gene

13,937,256 bp from pter
14,082,811 bp from pter
145,556 bases
Plus strand

Genomic View for TPRXL Gene

Genes around TPRXL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPRXL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPRXL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPRXL Gene

Proteins for TPRXL Gene

  • Protein details for TPRXL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative protein TPRXL
    Protein Accession:
    Secondary Accessions:
    • Q8NAM5

    Protein attributes for TPRXL Gene

    258 amino acids
    Molecular mass:
    24139 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TPRXL Gene

Proteomics data for TPRXL Gene at MOPED

Post-translational modifications for TPRXL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TPRXL Gene

Domains & Families for TPRXL Gene

Gene Families for TPRXL Gene

Protein Domains for TPRXL Gene


Suggested Antigen Peptide Sequences for TPRXL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TPRXL: view

No data available for UniProtKB/Swiss-Prot for TPRXL Gene

Function for TPRXL Gene

Phenotypes for TPRXL Gene

GenomeRNAi human phenotypes for TPRXL:
genes like me logo Genes that share phenotypes with TPRXL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TPRXL Gene

Localization for TPRXL Gene

Subcellular locations from

Jensen Localization Image for TPRXL Gene COMPARTMENTS Subcellular localization image for TPRXL gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TPRXL Gene

Pathways & Interactions for TPRXL Gene

SuperPathways for TPRXL Gene

No Data Available

Interacting Proteins for TPRXL Gene

Gene Ontology (GO) - Biological Process for TPRXL Gene


No data available for Pathways by source and SIGNOR curated interactions for TPRXL Gene

Drugs & Compounds for TPRXL Gene

No Compound Related Data Available

Transcripts for TPRXL Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TPRXL Gene

No ASD Table

Relevant External Links for TPRXL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TPRXL Gene

mRNA expression in normal human tissues for TPRXL Gene

mRNA differential expression in normal tissues according to GTEx for TPRXL Gene

This gene is overexpressed in Esophagus - Mucosa (x18.2), Vagina (x6.0), and Testis (x4.9).

SOURCE GeneReport for Unigene cluster for TPRXL Gene Hs.529180

genes like me logo Genes that share expression patterns with TPRXL: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TPRXL Gene

Orthologs for TPRXL Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TPRXL Gene

Organism Taxonomy Gene Similarity Type Details
(Triticum aestivum)
Liliopsida Ta.22819 35
Species with no ortholog for TPRXL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TPRXL Gene

Gene Tree for TPRXL (if available)
Gene Tree for TPRXL (if available)

Paralogs for TPRXL Gene

No data available for Paralogs for TPRXL Gene

Variants for TPRXL Gene

Sequence variations from dbSNP and Humsavar for TPRXL Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1077325 -- 13,951,149(-) ctata(A/C/T)ccctg intron-variant
rs1870132 -- 14,052,850(+) CAATG(C/G)TATGT intron-variant
rs1870133 -- 14,052,860(+) TATTT(C/T)ATTTT intron-variant
rs1873005 -- 14,018,723(-) CTGGA(C/T)TGTCC intron-variant
rs1906538 -- 13,972,669(-) ctcat(A/G)ctctc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TPRXL Gene

Variant ID Type Subtype PubMed ID
nsv876550 CNV Loss 21882294
esv34163 CNV Loss 18971310
nsv3711 CNV Insertion 18451855
esv2724945 CNV Deletion 23290073
esv2584514 CNV Insertion 19546169
nsv512797 CNV Insertion 21212237
esv2629351 CNV Deletion 19546169
esv269558 CNV Insertion 20981092
esv273722 CNV Insertion 20981092
nsv526467 CNV Loss 19592680

Variation tolerance for TPRXL Gene

Gene Damage Index Score: 10.74; 91.57% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TPRXL Gene

Disorders for TPRXL Gene

Relevant External Links for TPRXL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TPRXL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPRXL Gene

Publications for TPRXL Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women. (PMID: 22116950) Schuh-Huerta S.M. … Reijo Pera R.A. (Hum. Reprod. 2012) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TPRXL Gene

Sources for TPRXL Gene