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Aliases for TPRG1L Gene

Aliases for TPRG1L Gene

  • Tumor Protein P63 Regulated 1-Like 2 3
  • Mossy Fiber Terminal-Associated Vertebrate-Specific Presynaptic Protein 3 4
  • Family With Sequence Similarity 79, Member A 2 3
  • FAM79A 3 4
  • Mover 3 4
  • Tumor Protein P63-Regulated Gene 1-Like Protein 3
  • Protein FAM79A 4
  • RP11-46F15.3 3
  • H-Mover 3

External Ids for TPRG1L Gene

Previous HGNC Symbols for TPRG1L Gene

  • FAM79A

Previous GeneCards Identifiers for TPRG1L Gene

  • GC01P002837

Summaries for TPRG1L Gene

GeneCards Summary for TPRG1L Gene

TPRG1L (Tumor Protein P63 Regulated 1-Like) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is TPRG1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPRG1L Gene

Genomics for TPRG1L Gene

Regulatory Elements for TPRG1L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TPRG1L Gene

Start:
3,624,992 bp from pter
End:
3,630,131 bp from pter
Size:
5,140 bases
Orientation:
Plus strand

Genomic View for TPRG1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TPRG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPRG1L Gene

Proteins for TPRG1L Gene

  • Protein details for TPRG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0D9-TPRGL_HUMAN
    Recommended name:
    Tumor protein p63-regulated gene 1-like protein
    Protein Accession:
    Q5T0D9
    Secondary Accessions:
    • A8K1K4
    • Q8WV04

    Protein attributes for TPRG1L Gene

    Size:
    272 amino acids
    Molecular mass:
    30212 Da
    Quaternary structure:
    • Interacts with BSN.

    Alternative splice isoforms for TPRG1L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TPRG1L Gene

Proteomics data for TPRG1L Gene at MOPED

Post-translational modifications for TPRG1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TPRG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TPRG1L Gene

Domains for TPRG1L Gene

Protein Domains for TPRG1L Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TPRG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T0D9

UniProtKB/Swiss-Prot:

TPRGL_HUMAN :
  • Q5T0D9
Family:
  • Belongs to the TPRG1 family.
genes like me logo Genes that share domains with TPRG1L: view

No data available for Gene Families for TPRG1L Gene

Function for TPRG1L Gene

Gene Ontology (GO) - Molecular Function for TPRG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with TPRG1L: view

Phenotypes for TPRG1L Gene

GenomeRNAi human phenotypes for TPRG1L:
genes like me logo Genes that share phenotypes with TPRG1L: view

Animal Model Products

CRISPR Products

miRNA for TPRG1L Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TPRG1L Gene

Localization for TPRG1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TPRG1L Gene

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Localized to presynaptic nerve terminals. {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TPRG1L Gene COMPARTMENTS Subcellular localization image for TPRG1L gene
Compartment Confidence
cytoskeleton 2
cytosol 2
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TPRG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008021 synaptic vesicle ISS 17869247
GO:0030054 cell junction IEA --
GO:0070062 extracellular exosome IDA 19199708
genes like me logo Genes that share ontologies with TPRG1L: view

Pathways for TPRG1L Gene

SuperPathways for TPRG1L Gene

No Data Available

Interacting Proteins for TPRG1L Gene

Selected Interacting proteins: Q5T0D9-TPRGL_HUMAN for TPRG1L Gene via I2D

Symbol External ID(s) Details
MED6
MLH1

Gene Ontology (GO) - Biological Process for TPRG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TPRG1L: view

No data available for Pathways by source for TPRG1L Gene

Transcripts for TPRG1L Gene

mRNA/cDNA for TPRG1L Gene

Unigene Clusters for TPRG1L Gene

Tumor protein p63 regulated 1-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TPRG1L

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TPRG1L
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TPRG1L Gene

No ASD Table

Relevant External Links for TPRG1L Gene

GeneLoc Exon Structure for
TPRG1L
ECgene alternative splicing isoforms for
TPRG1L

Expression for TPRG1L Gene

mRNA expression in normal human tissues for TPRG1L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TPRG1L Gene

SOURCE GeneReport for Unigene cluster for TPRG1L Gene Hs.20529

genes like me logo Genes that share expressions with TPRG1L: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TPRG1L Gene

Orthologs for TPRG1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TPRG1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TPRG1L 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TPRG1L 35
  • 85.29 (n)
  • 90.44 (a)
TPRG1L 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TPRG1L 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tprgl 35
  • 87.09 (n)
  • 91.73 (a)
Tprgl 16
Tprgl 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TPRG1L 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TPRG1L 36
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tprg1l 35
  • 86.59 (n)
  • 91.35 (a)
chicken
(Gallus gallus)
Aves TPRG1L 35
  • 77.35 (n)
  • 83.98 (a)
TPRG1L 36
  • 61 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.23748 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11829 35
tprg1l 35
  • 71.49 (n)
  • 73.25 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.15200 35
tprg1l 35
  • 67.77 (n)
  • 71.69 (a)
tprg1l 36
  • 70 (a)
OneToOne
Species with no ortholog for TPRG1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TPRG1L Gene

ENSEMBL:
Gene Tree for TPRG1L (if available)
TreeFam:
Gene Tree for TPRG1L (if available)

Paralogs for TPRG1L Gene

Paralogs for TPRG1L Gene

Selected SIMAP similar genes for TPRG1L Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TPRG1L Gene

genes like me logo Genes that share paralogs with TPRG1L: view

Variants for TPRG1L Gene

Sequence variations from dbSNP and Humsavar for TPRG1L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs8029 -- 3,629,928(-) GCAAG(C/T)CAGTG utr-variant-3-prime
rs1128472 -- 3,628,824(+) TATAA(A/G)CTACA utr-variant-3-prime
rs1128473 -- 3,628,868(+) CTGCT(A/G)GTATT utr-variant-3-prime
rs1128474 -- 3,629,048(+) CAAGT(A/G)TGTTT utr-variant-3-prime
rs1128527 -- 3,630,069(+) ATTAA(A/G)AAGTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TPRG1L Gene

Variant ID Type Subtype PubMed ID
nsv871581 CNV Loss 21882294
dgv95n71 CNV Loss 21882294
dgv96n71 CNV Loss 21882294
nsv470687 CNV Loss 18288195
dgv12e1 CNV Complex 17122850
dgv99n71 CNV Loss 21882294
dgv103n71 CNV Loss 21882294
dgv108n71 CNV Loss 21882294
nsv871823 CNV Loss 21882294
nsv871942 CNV Loss 21882294
dgv109n71 CNV Loss 21882294
dgv110n71 CNV Loss 21882294
dgv111n71 CNV Loss 21882294
dgv112n71 CNV Loss 21882294
nsv870859 CNV Loss 21882294

Relevant External Links for TPRG1L Gene

HapMap Linkage Disequilibrium report
TPRG1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TPRG1L Gene

Disorders for TPRG1L Gene

No disorders were found for TPRG1L Gene.

No data available for UniProtKB/Swiss-Prot for TPRG1L Gene

Publications for TPRG1L Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Mover is a novel vertebrate-specific presynaptic protein with differential distribution at subsets of CNS synapses. (PMID: 17869247) Kremer T. … Dresbach T. (FEBS Lett. 2007) 3

Products for TPRG1L Gene

  • antibodies-online proteins for TPRG1L
  • antibodies-online antibodies for TPRG1L
  • antibodies-online kits for TPRG1L

Sources for TPRG1L Gene

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