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Aliases for TPRG1L Gene

Aliases for TPRG1L Gene

  • Tumor Protein P63 Regulated 1-Like 2 3 5
  • Mossy Fiber Terminal-Associated Vertebrate-Specific Presynaptic Protein 3 4
  • Family With Sequence Similarity 79, Member A 2 3
  • FAM79A 3 4
  • Mover 3 4
  • Protein FAM79A 4
  • RP11-46F15.3 3
  • H-Mover 3

External Ids for TPRG1L Gene

Previous HGNC Symbols for TPRG1L Gene

  • FAM79A

Previous GeneCards Identifiers for TPRG1L Gene

  • GC01P003532
  • GC01P002837

Summaries for TPRG1L Gene

GeneCards Summary for TPRG1L Gene

TPRG1L (Tumor Protein P63 Regulated 1-Like) is a Protein Coding gene. GO annotations related to this gene include identical protein binding. An important paralog of this gene is TPRG1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPRG1L Gene

Genomics for TPRG1L Gene

Regulatory Elements for TPRG1L Gene

Enhancers for TPRG1L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TPRG1L on UCSC Golden Path with GeneCards custom track

Promoters for TPRG1L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TPRG1L on UCSC Golden Path with GeneCards custom track

Genomic Location for TPRG1L Gene

3,624,992 bp from pter
3,630,131 bp from pter
5,140 bases
Plus strand

Genomic View for TPRG1L Gene

Genes around TPRG1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TPRG1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TPRG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPRG1L Gene

Proteins for TPRG1L Gene

  • Protein details for TPRG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tumor protein p63-regulated gene 1-like protein
    Protein Accession:
    Secondary Accessions:
    • A8K1K4
    • Q8WV04

    Protein attributes for TPRG1L Gene

    272 amino acids
    Molecular mass:
    30212 Da
    Quaternary structure:
    • Interacts with BSN.

    Alternative splice isoforms for TPRG1L Gene


neXtProt entry for TPRG1L Gene

Proteomics data for TPRG1L Gene at MOPED

Post-translational modifications for TPRG1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TPRG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TPRG1L Gene

Domains & Families for TPRG1L Gene

Protein Domains for TPRG1L Gene


Suggested Antigen Peptide Sequences for TPRG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 hSac2 domain.
  • Belongs to the TPRG1 family.
  • Contains 1 hSac2 domain.
  • Belongs to the TPRG1 family.
genes like me logo Genes that share domains with TPRG1L: view

No data available for Gene Families for TPRG1L Gene

Function for TPRG1L Gene

genes like me logo Genes that share phenotypes with TPRG1L: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TPRG1L Gene

Localization for TPRG1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TPRG1L Gene

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Localized to presynaptic nerve terminals. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for TPRG1L Gene COMPARTMENTS Subcellular localization image for TPRG1L gene
Compartment Confidence
extracellular 5
cytoskeleton 2
cytosol 2
nucleus 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for TPRG1L Gene

Pathways & Interactions for TPRG1L Gene

SuperPathways for TPRG1L Gene

No Data Available

Interacting Proteins for TPRG1L Gene

Selected Interacting proteins: Q5T0D9-TPRGL_HUMAN for TPRG1L Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TPRG1L Gene


No data available for Pathways by source and SIGNOR curated interactions for TPRG1L Gene

Drugs & Compounds for TPRG1L Gene

No Compound Related Data Available

Transcripts for TPRG1L Gene

mRNA/cDNA for TPRG1L Gene

Unigene Clusters for TPRG1L Gene

Tumor protein p63 regulated 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TPRG1L Gene

No ASD Table

Relevant External Links for TPRG1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TPRG1L Gene

mRNA expression in normal human tissues for TPRG1L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TPRG1L Gene

This gene is overexpressed in Frontal cortex (24.3) and Brain (8.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for TPRG1L Gene

SOURCE GeneReport for Unigene cluster for TPRG1L Gene Hs.20529

genes like me logo Genes that share expression patterns with TPRG1L: view

Protein tissue co-expression partners for TPRG1L Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TPRG1L Gene

Orthologs for TPRG1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TPRG1L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TPRG1L 35
  • 85.29 (n)
  • 90.44 (a)
  • 89 (a)
(Mus musculus)
Mammalia Tprgl 35
  • 87.09 (n)
  • 91.73 (a)
Tprgl 16
Tprgl 36
  • 92 (a)
(Rattus norvegicus)
Mammalia Tprg1l 35
  • 86.59 (n)
  • 91.35 (a)
(Canis familiaris)
Mammalia TPRG1L 36
  • 95 (a)
(Monodelphis domestica)
Mammalia TPRG1L 36
  • 81 (a)
(Ornithorhynchus anatinus)
Mammalia TPRG1L 36
  • 88 (a)
(Pan troglodytes)
Mammalia TPRG1L 36
  • 96 (a)
(Gallus gallus)
Aves TPRG1L 35
  • 77.35 (n)
  • 83.98 (a)
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.11829 35
tprg1l 35
  • 71.49 (n)
  • 73.25 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.23748 35
(Danio rerio)
Actinopterygii Dr.15200 35
tprg1l 35
  • 67.77 (n)
  • 71.69 (a)
tprg1l 36
  • 70 (a)
Species with no ortholog for TPRG1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TPRG1L Gene

Gene Tree for TPRG1L (if available)
Gene Tree for TPRG1L (if available)

Paralogs for TPRG1L Gene

Paralogs for TPRG1L Gene

(1) SIMAP similar genes for TPRG1L Gene using alignment to 1 proteins: Pseudogenes for TPRG1L Gene

genes like me logo Genes that share paralogs with TPRG1L: view

Variants for TPRG1L Gene

Sequence variations from dbSNP and Humsavar for TPRG1L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs8029 -- 3,629,928(-) GCAAG(C/T)CAGTG utr-variant-3-prime
rs1128472 -- 3,628,824(+) TATAA(A/G)CTACA utr-variant-3-prime
rs1128473 -- 3,628,868(+) CTGCT(A/G)GTATT utr-variant-3-prime
rs1128474 -- 3,629,048(+) CAAGT(A/G)TGTTT utr-variant-3-prime
rs1128527 -- 3,630,069(+) ATTAA(A/G)AAGTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TPRG1L Gene

Variant ID Type Subtype PubMed ID
nsv871581 CNV Loss 21882294
dgv95n71 CNV Loss 21882294
dgv96n71 CNV Loss 21882294
nsv470687 CNV Loss 18288195
dgv12e1 CNV Complex 17122850
dgv99n71 CNV Loss 21882294
dgv103n71 CNV Loss 21882294
dgv108n71 CNV Loss 21882294
nsv871823 CNV Loss 21882294
nsv871942 CNV Loss 21882294
dgv109n71 CNV Loss 21882294
dgv110n71 CNV Loss 21882294
dgv111n71 CNV Loss 21882294
dgv112n71 CNV Loss 21882294
nsv870859 CNV Loss 21882294

Variation tolerance for TPRG1L Gene

Residual Variation Intolerance Score: 32% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.29; 6.46% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TPRG1L Gene

Disorders for TPRG1L Gene

Relevant External Links for TPRG1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TPRG1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TPRG1L Gene

Publications for TPRG1L Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). (PMID: 19199708) Gonzalez-Begne M. … Yates J.R. (J. Proteome Res. 2009) 3
  4. Mover is a novel vertebrate-specific presynaptic protein with differential distribution at subsets of CNS synapses. (PMID: 17869247) Kremer T. … Dresbach T. (FEBS Lett. 2007) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for TPRG1L Gene

Sources for TPRG1L Gene