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Aliases for TPRG1 Gene

Aliases for TPRG1 Gene

  • Tumor Protein P63 Regulated 1 2 3
  • Family With Sequence Similarity 79, Member B 2 3
  • FAM79B 3 4
  • Tumor Protein P63-Regulated Gene 1 Protein 3
  • Protein FAM79B 4

External Ids for TPRG1 Gene

Previous Symbols for TPRG1 Gene

  • FAM79B

Summaries for TPRG1 Gene

GeneCards Summary for TPRG1 Gene

TPRG1 (Tumor Protein P63 Regulated 1) is a Protein Coding gene. An important paralog of this gene is TPRG1L.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TPRG1 Gene

Genomics for TPRG1 Gene

Genomic Location for TPRG1 Gene

Start:
188,947,214 bp from pter
End:
189,325,304 bp from pter
Size:
378,091 bases
Orientation:
Plus strand

Genomic View for TPRG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TPRG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TPRG1 Gene

Regulatory Elements for TPRG1 Gene

Proteins for TPRG1 Gene

  • Protein details for TPRG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZUI0-TPRG1_HUMAN
    Recommended name:
    Tumor protein p63-regulated gene 1 protein
    Protein Accession:
    Q6ZUI0
    Secondary Accessions:

    Protein attributes for TPRG1 Gene

    Size:
    275 amino acids
    Molecular mass:
    31230 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TPRG1 Gene

Proteomics data for TPRG1 Gene at MOPED

Post-translational modifications for TPRG1 Gene

No Post-translational modifications

Other Protein References for TPRG1 Gene

No data available for DME Specific Peptides for TPRG1 Gene

Domains for TPRG1 Gene

Protein Domains for TPRG1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TPRG1_HUMAN
Family:
  • Belongs to the TPRG1 family.:
    • Q6ZUI0
genes like me logo Genes that share domains with TPRG1: view

No data available for Gene Families for TPRG1 Gene

Function for TPRG1 Gene

Phenotypes for TPRG1 Gene

GenomeRNAi human phenotypes for TPRG1:
genes like me logo Genes that share phenotypes with TPRG1: view

miRNA for TPRG1 Gene

miRTarBase miRNAs that target TPRG1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TPRG1 Gene

Localization for TPRG1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TPRG1 Gene COMPARTMENTS Subcellular localization image for TPRG1 gene
Compartment Confidence
cytoskeleton 2
cytosol 2
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TPRG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TPRG1: view

Pathways for TPRG1 Gene

SuperPathways for TPRG1 Gene

No Data Available

Interacting Proteins for TPRG1 Gene

Gene Ontology (GO) - Biological Process for TPRG1 Gene

None

No data available for Pathways by source for TPRG1 Gene

Transcripts for TPRG1 Gene

Unigene Clusters for TPRG1 Gene

Tumor protein p63 regulated 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TPRG1 Gene

No ASD Table

Relevant External Links for TPRG1 Gene

GeneLoc Exon Structure for
TPRG1
ECgene alternative splicing isoforms for
TPRG1

Expression for TPRG1 Gene

mRNA expression in normal human tissues for TPRG1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TPRG1 Gene

This gene is overexpressed in Esophagus - Mucosa (9.8), Vagina (6.7), Skin - Sun Exposed (Lower leg) (5.9), Skin - Not Sun Exposed (Suprapubic) (5.4), and Cervix - Ectocervix (4.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TPRG1 Gene

SOURCE GeneReport for Unigene cluster for TPRG1 Gene Hs.729544

genes like me logo Genes that share expressions with TPRG1: view

Orthologs for TPRG1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TPRG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TPRG1 36
  • 99.52 (n)
  • 99.64 (a)
TPRG1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TPRG1 36
  • 87.52 (n)
  • 86.55 (a)
TPRG1 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TPRG1 36
  • 90.18 (n)
  • 91.27 (a)
TPRG1 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tprg 36
  • 84.73 (n)
  • 82.55 (a)
Tprg 16
Tprg 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TPRG1 37
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TPRG1 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tprg1 36
  • 84.91 (n)
  • 82.85 (a)
lizard
(Anolis carolinensis)
Reptilia TPRG1 37
  • 57 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia MGC68514 36
tropical clawed frog
(Silurana tropicalis)
Amphibia tprg1 36
  • 60.49 (n)
  • 57.41 (a)
zebrafish
(Danio rerio)
Actinopterygii tprg1 36
  • 57.05 (n)
  • 47.31 (a)
tprg1 37
  • 43 (a)
OneToOne
Species with no ortholog for TPRG1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TPRG1 Gene

ENSEMBL:
Gene Tree for TPRG1 (if available)
TreeFam:
Gene Tree for TPRG1 (if available)

Paralogs for TPRG1 Gene

Paralogs for TPRG1 Gene

Selected SIMAP similar genes for TPRG1 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for TPRG1 Gene

genes like me logo Genes that share paralogs with TPRG1: view

Variants for TPRG1 Gene

Sequence variations from dbSNP and Humsavar for TPRG1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs716956 -- 189,208,109(-) GCACA(A/G)GTAAG intron-variant
rs719405 -- 189,208,188(-) AAATA(C/T)TGCTT intron-variant
rs719406 -- 189,208,083(-) CTGGT(A/C)GCTGT intron-variant
rs719407 -- 189,208,053(-) ACCTG(C/T)TCCCT intron-variant
rs730615 -- 189,194,921(-) CTGCT(C/G)AGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TPRG1 Gene

Variant ID Type Subtype PubMed ID
nsv829819 CNV Gain 17160897
nsv236710 CNV Loss 16902084
esv2726358 CNV Deletion 23290073

Relevant External Links for TPRG1 Gene

HapMap Linkage Disequilibrium report
TPRG1

Disorders for TPRG1 Gene

(1) University of Copenhagen DISEASES for TPRG1 Gene

Relevant External Links for TPRG1

Genetic Association Database (GAD)
TPRG1
Human Genome Epidemiology (HuGE) Navigator
TPRG1
genes like me logo Genes that share disorders with TPRG1: view

No data available for UniProtKB/Swiss-Prot for TPRG1 Gene

Publications for TPRG1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study. (PMID: 19475631) Evangelou E. … Ioannidis J.P. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010) 3 49
  4. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. (PMID: 24144296) Cheng C.Y. … Baird P.N. (Am. J. Hum. Genet. 2013) 3
  5. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang S.J. … Fox C.S. (BMC Med. Genet. 2007) 49

Products for TPRG1 Gene

Sources for TPRG1 Gene

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