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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TPPP3 Gene

protein-coding   GIFtS: 48
GCID: GC16M067423

tubulin polymerization-promoting protein family member 3
 Explore 30 diseases affiliated with
TPPP3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TPPP3    

Aliases
for TPPP3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tubulin Polymerization-Promoting Protein Family Member 31 2
P201
P25gamma1
TPPP/P201
CGI-381
Brain Specific Protein2

External Ids:    HGNC: 241621   Entrez Gene: 516732   Ensembl: ENSG000001597137   UniProtKB: Q9BW303   

Export aliases for TPPP3 gene to outside databases

Previous GC identifers: GC16M065984 GC16M053296


Summaries
for TPPP3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: TPPP3_HUMAN, Q9BW30
Function: Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis




Genomic Views
for TPPP3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TPPP3 gene promoter:
         MIF-1   Nkx2-5   HEN1   SRY   PPAR-gamma1   ARP-1   ZIC2/Zic2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TPPP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TPPP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPPP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

TPPP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TPPP3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M067423:  view genomic region     (about GC identifiers)

Start:
 67,423,712 bp from pter      End:
 67,427,438 bp from pter
Size:
 3,727 bases      Orientation:
 minus strand

Proteins
for TPPP3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TPPP3_HUMAN, Q9BW30 (See protein sequence)
Recommended Name: Tubulin polymerization-promoting protein family member 3  
Size: 176 amino acids; 18985 Da
Subcellular location: Cytoplasm, cytoskeleton (Probable)
Sequence caution: Sequence=AAD44478.1; Type=Frameshift; Positions=52, 77, 83, 89;
1 PDB 3D structure from and Proteopedia for TPPP3:
2JRF (3D)    
Secondary accessions: Q49AH9 Q9Y326 Q9Y6H0

Explore the universe of human proteins at neXtProt for TPPP3: NX_Q9BW30

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BW30

    • TPPP3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_057048.2  NP_057224.2  

    ENSEMBL proteins: 
     ENSP00000377529   ENSP00000462435   ENSP00000290942   ENSP00000457275  

    Human Recombinant Protein Products: 
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    Novus Biologicals TPPP3 Protein
    Novus Biologicals TPPP3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TPPP3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005874microtubule IEA--


    TPPP3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for TPPP3

    Protein Domains /
    Families
    for TPPP3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TPPP3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR008907 P25-alpha

    Graphical View of Domain Structure for InterPro Entry Q9BW30

    ProtoNet protein and cluster: Q9BW30

    1 Blocks protein family: IPB008907 P25-alpha

    UniProtKB/Swiss-Prot: TPPP3_HUMAN, Q9BW30
    Similarity: Belongs to the TPPP family


    Function
    for TPPP3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TPPP3_HUMAN, Q9BW30
    Function: Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis

    miRNA
    Products:            		miRTarBase miRNAs that target TPPP3:
    hsa-mir-16 (MIRT004470)

    OriGene 3'-UTR Clone (see all 2): TPPP3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TPPP3
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TPPP3 (see all 12):
    hsa-miR-1321 hsa-miR-15a hsa-miR-2278 hsa-miR-497 hsa-miR-646 hsa-miR-424 hsa-miR-654-5p hsa-miR-2114*
    SwitchGear 3'UTR luciferase reporter plasmid: TPPP3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPPP3 (see all 4)
    OriGene shRNA RFP: TPPP3
    OriGene siRNA: TPPP3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPPP3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TPPP3

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TPPP3 (see all 4)
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPPP3 

    Cell Line
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    Search LifeMap BioReagents cell lines for TPPP3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPPP3

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding ----
    GO:0015631tubulin binding IDA17105200


    TPPP3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TPPP3:
     Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for TPPP3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TPPP3

    5/7 Interacting proteins for TPPP3 (Q9BW303) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP6V1G1O753483I2D: score=5 
    RPS3P233963I2D: score=5 
    DOCK1Q141853I2D: score=4 
    PLK1P533503I2D: score=4 
    RPS7P620813I2D: score=4 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001578microtubule bundle formation IDA17105200


    TPPP3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TPPP3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TPPP3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TPPP3
    2 Novoseek chemical compound relationships for TPPP3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 0 2 8561965 (1), 8812417 (1)
    dopamine 0 1 8561965 (1)

    Search CenterWatch for drugs/clinical trials and news about TPPP3 

    Transcripts
    for TPPP3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TPPP3 gene (2 alternative transcripts): 
    NM_015964.2  NM_016140.2  

    Unigene Cluster for TPPP3:

    Tubulin polymerization-promoting protein family member 3
    Hs.534458  [show with all ESTs]
    Unigene Representative Sequence: BM806025
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393957(uc002etb.3) ENST00000564104(uc002esz.3) ENST00000290942(uc002eta.3)
    ENST00000562206 ENST00000561537

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): TPPP3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TPPP3
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate TPPP3 (see all 12):
    hsa-miR-1321 hsa-miR-15a hsa-miR-2278 hsa-miR-497 hsa-miR-646 hsa-miR-424 hsa-miR-654-5p hsa-miR-2114*
    SwitchGear 3'UTR luciferase reporter plasmid: TPPP3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPPP3 (see all 4)
    OriGene shRNA RFP: TPPP3
    OriGene siRNA: TPPP3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TPPP3
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPPP3 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TPPP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TPPP3

    Additional cDNA sequence: 

    AF078846.1 AF132972.1 BC000691.2 

    11 DOTS entries:

    DT.214319  DT.100758382  DT.100805405  DT.120715523  DT.100805403  DT.99928237  DT.75154625  DT.95199640 
    DT.95227224  DT.100805408  DT.95294813 

    24/283 AceView cDNA sequences (see all 283):

    BU677814 BQ721629 AI418500 AW087326 BC000691 AI160184 BM976416 CR612698 
    AI688738 BM741052 AI247537 NM_013304 U90653 BM721377 BF436170 BM724650 
    CR594676 BM739156 BM670761 AI800838 CF455376 AW149915 AI955395 BI754230 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TPPP3    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d
    SP1:              -           -                                       
    SP2:              -     -     -                                       
    SP3:                          -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for TPPP3

    Expression
    for TPPP3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TPPP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCTAACCCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TPPP3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor CellsMotor Neurons
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Spinal CordSpinal Ventral ColumnsSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor SM22 (Embryonic Progenitor Cell)

    See TPPP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TPPP3

    SOURCE GeneReport for Unigene cluster: Hs.534458
        SABiosciences Custom PCR Arrays for TPPP3
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPPP3

    Orthologs
    for TPPP3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TPPP3 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TPPP31 tubulin polymerization-promoting protein family member more 79.74(n)
    84.97(a)    		   415669  XM_003641899.1  XP_003641947.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TPPP36
    		 --
    		 84(a)
    		 1 ↔ 1
    		 GL343295.1(294494-299912)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.29082 Xenopus laevis transcribed sequence with weak similarity more 73.75(n)    48022524 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc779342 hypothetical protein MGC77934 75.08(n)   393825  BC062530.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG48936
    		 --
    		 36(a)
    		 1 → many
    		 3L(16347846-16352528)
    worm
    (Caenorhabditis elegans)    		 Secernentea C32E8.36
    		 TPPP family protein C32E8.3
    		 38(a)
    		 1 → many
    		 I(3786597-3787498)


    ENSEMBL Gene Tree for TPPP3 (if available)
    TreeFam Gene Tree for TPPP3 (if available) 

    Paralogs
    for TPPP3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TPPP3 gene
    TPPP2  TPPP22  
    3 SIMAP similar genes for TPPP3 using alignment to 1 protein entry:     TPPP3_HUMAN:
    TPPP2    FREP1    TPPP

    TPPP3 for paralogs           About GeneDecksing



    Genomic Variants
    for TPPP3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/75 NCBI SNPs in TPPP3 are shown (see all 75)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 16 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs115523221,2
    		C,F,other67424412(-) GTGGCA/G/TGGCAA 6 A syn1 ese33NA EU 5932
    rs1821628831,2
    		--67423231(+) CCACCA/GCGCCC 2 -- int10--------
    rs772841241,2
    		--67423332(+) CTGTTC/TGCAGA 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1860750391,2
    		--67423333(+) TGTTCA/GCAGAC 2 -- int10--------
    rs1416035701,2
    		--67423537(+) AGTCTC/TCTCAG 2 -- int10--------
    rs758854561,2
    		C,F,--67423691(+) CCCCCA/GTCATC 2 -- int11Minor allele frequency- G:0.03WA 118
    rs10536121,2
    		C,F,A,H,--67423939(-) CCCACT/CGGGCT 2 -- ut31 ese320Minor allele frequency- C:0.33MN NS EA NA WA CSA 2203
    rs1899096991,2
    		--67423977(+) TCCAGC/TAGGGA 2 -- ut310--------
    rs2002286861,2
    		--67424035(+) GCCTCC/TGGCAG 2 -- ut310--------
    rs115523191,2
    		C,F,H,--67424122(+) TAGGCG/ACTCAC 4 /S syn128Minor allele frequency- A:0.11NA NS EA CSA WA EU 8431

    HapMap Linkage Disequilibrium report for TPPP3 (67423712 - 67427438 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TPPP3: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TPPP3
    DNA2.0 Custom Variant and Variant Library Synthesis for TPPP3

    Disorders / Diseases
    for TPPP3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TPPP3 for disorders           About GeneDecksing

    20/30 diseases for TPPP3 (see all 30):    About MalaCards
    variant creutzfeldt-jakob disease    cerebrospinal fluid leak    tick-borne encephalitis    spinal cord injury
    traumatic brain injury    aids dementia complex    brain injury    optic neuritis
    amyotrophic lateral sclerosis    lateral sclerosis    multiple system atrophy    myelomeningocele
    neuritis    encephalitis    neurodegenerative disease    prion disease
    huntington's disease    lyme disease    brain disease    parkinson's disease

    10/12 Novoseek disease relationships for TPPP3 gene (see all 12)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    creutzfeldt-jakob disease 51.2 1 11385008 (1)
    neurodegenerative diseases 42.1 2 12542908 (2)
    neurological disorders 41.1 1 14530574 (1)
    huntington disease 36.3 2 18984577 (1)
    dementia 34 2 16128180 (1), 9137895 (1)
    brain diseases 33.7 2 1704202 (1), 10594376 (1)
    multiple sclerosis 31.8 1 15222688 (1)
    parkinson disease 31.4 1 17105200 (1)
    encephalitis 24.1 2 11983209 (2)
    asphyxia 20.7 2 12736385 (2)


    Export disorders for TPPP3 gene to outside databases

    Publications
    for TPPP3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TPPP3 gene, integrated from 9 sources (see all 99):
    (articles sorted by number of sources associating them with TPPP3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions. (PubMed id 17105200)1, 2, 3, 9 Vincze O....Ovadi J. (2006)
    2. Depletion of tubulin polymerization promoting protein family member 3 suppresses HeLa cell proliferation. (PubMed id 19633818)1, 2 Zhou W.... Hu R. (2009)
    3. p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies. (PubMed id 15590652)1, 3 Lindersson E....Jensen P.H. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
    6. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. (PubMed id 19165527)1 Martins-de-Souza D....Turck C.W. (2009)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Expressed sequence tag analysis of human retina for the NEIBank project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. (PubMed id 12107411)1 Wistow G.... Peterson K. (2002)

    External Searches for TPPP3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TPPP3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51673 HGNC: 24162 AceView: ZDHHC1andCGI-38 Ensembl:ENSG00000159713 euGenes: HUgn51673
    ECgene: TPPP3 H-InvDB: TPPP3

    Other Databases showing TPPP3 gene

    (According to HUGE)
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    Specialized Databases showing TPPP3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TPPP3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TPPP3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TPPP3 gene:
    Search GeneIP for patents involving TPPP3

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