TPM4 Gene
protein-coding GIFtS : 61 GCID: GC19 P017060
tropomyosin 4
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Aliasesfor TPM4 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Tropomyosin 4 1 2 TM30p12 3 Tropomyosin Alpha-4 Chain2 Tropomyosin-43 Tropomyosin-43
Export aliases for TPM4 gene to outside databases Previous GC identifers: GC19P016682 GC19P016571 GC19P016023 GC19P016048 GC19P016039 GC19P016178 GC19P015749
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Summariesfor TPM4 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for TPM4 : This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Nov 2009) UniProtKB/Swiss-Prot: TPM4_HUMAN, P67936 Function : Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with thetroponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium Gene Wiki entry for TPM4
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Genomic Viewsfor TPM4 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000019.9 NC_018930.1 NT_011295.11 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TPM4 gene promoter:CHOP-10 CREB MZF-1 ARP-1 AP-4 Roaz C/EBPalpha Other transcription factors Search SABiosciences Chromatin IP Primers for TPM4 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 19p13.1 Ensembl cytogenetic band: 19p13.12 HGNC cytogenetic band: 19p13.1 TPM4 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 19 GeneLoc Exon Structure
GeneLoc location for GC19P017060: view genomic region
(about GC identifiers )
Start: 16,177,831 bp from pter End:
16,213,813 bp from pter
Size: 35,983 bases Orientation:
plus strand
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Proteinsfor TPM4 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: TPM4_HUMAN, P67936 See
protein sequence )Recommended Name: Size : 248 amino acids; 28522 DaSubunit : Heterodimer of an alpha and a beta chain (By similarity)Subcellular location : Cytoplasm, cytoskeletonSecondary accessions : P07226 Q15659 Q5U0D9 Q9BU85 Q9H8Q3 Q9UCS1 Q9UCS2 Q9UCS3 Q9UCS4Alternative splicing : 2 isoforms : P67936-1, P07226-1 P67936-2, P07226-2 Explore the universe of human proteins at neXtProt for TPM4: NX_P67936 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_P67936 TPM4 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (2 alternative transcripts): NP_001138632.1 NP_003281.1 ENSEMBL proteins: ENSP00000466158 ENSP00000345230 ENSP00000468246 ENSP00000467087 ENSP00000467558 ENSP00000300933 ENSP00000467250 ENSP00000466106 ENSP00000466654 ENSP00000467319 ENSP00000468010 ENSP00000439135 Reactome Protein details: P67936 Human Recombinant Protein Products for TPM4: Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8 ): About this table
About GeneDecksing TPM4 Antibody Products: Assay Products for TPM4:
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Protein
Domains /for TPM4 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry P67936 ProtoNet protein and cluster: P67936
UniProtKB/Swiss-Prot: TPM4_HUMAN, P67936 Domain : The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits aprominent seven-residues periodicity Similarity : Belongs to the tropomyosin family
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Functionfor TPM4 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: TPM4_HUMAN, P67936 Function : Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with thetroponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium
Genatlas biochemistry entry for TPM4 tropomyosin 4,alpha,skeletal muscle and non muscle isoforms,dimerizing to form a helical coiled coil binding to actin in the troponin complex (thin filamant) that regulates calcium-dependent binding of actin and myosin and muscle contraction Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing Animal Models: Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 4 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): TPM4 (NM_003290 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPM4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TPM4
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPM4
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Pathways & Interactionsfor TPM4 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 Striated Muscle Contraction 2 Hypertrophic cardiomyopathy (HCM) 3 Cardiac muscle contraction
Pathway sources See GeneCards unified pathways Show all pathways 1 3 3 (Kegg details for TPM4) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TPM4 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/101 Interacting proteins for TPM4 (P67936 3 ENSP00000345230 4 via UniProtKB, MINT, STRING , and/or I2D (see all 101 )About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
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Drugs & Compoundsfor TPM4 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TPM4 1 HMDB Compound for TPM4 About this table TPM4
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Transcriptsfor TPM4 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
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SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for TPM4 gene (2 alternative transcripts): NM_001145160.1 NM_003290.2 Unigene Cluster for TPM4:
Tropomyosin 4 Hs.631618 [show with all ESTs ] Unigene Representative Sequence: AK056565 17 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000589897 ENST00000344824 (uc002ndi.2 ) ENST00000586499 ENST00000586833 ENST00000588507 ENST00000300933 (uc002ndj.2 ) ENST00000587201 ENST00000588410 ENST00000590180 ENST00000588483 ENST00000592138 ENST00000588032 ENST00000586193 ENST00000591645 ENST00000592822 ENST00000591226 ENST00000538887 (uc002ndk.1 )Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 4 )human mouse rat see all 3 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): TPM4 (NM_003290 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TPM4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TPM4
Additional cDNA sequence: AF186109.1 AK023385.1 AK056565.1 AK095546.1 AK125191.1 AK300136.1 AK301285.1 AK307538.1 AK315076.1 BC002827.2 BC037576.1 BC067225.1 BT019634.1 M12127.1 X05276.1 Z36778.1
24/36 DOTS entries (see all 36 ): DT.97866054 DT.70101123
DT.97870025 DT.97821601 DT.95346341 DT.99990532 DT.95252375 DT.121478976 DT.100893663 DT.97870006 DT.75194236 DT.100893658 DT.121478979 DT.121478983 DT.121479013 DT.121479040 DT.86842758 DT.86992837 DT.92470231 DT.100035474 DT.121478963 DT.121479036 DT.91909262 DT.92045343 24/460 AceView cDNA sequences (see all 460 ):
AA043959 BE073620 BQ214144 BQ706675 BQ898783 AW511633 AI744235 BC037576 BM875323 BF770022 CA392344 BQ438234 AW580721 BQ420588 AA096433 T28637 BF326057 BU947634 BP354710 AI587345 BM820916 BM464266 CB135860 BQ712716 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TPM4 (see all 7 ) About this scheme ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b SP1 : - - - - - - SP2 : - - - - SP3 : - SP4 : - SP5 : - - -
ECgene alternative splicing isoforms for TPM4
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Expression for TPM4 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TPM4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TCTCTACTAAAbout this image TPM4 expression in embryonic tissues and stem cells About this table
See TPM4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TPM4 SOURCE GeneReport for Unigene cluster: Hs.631618 UniProtKB/Swiss-Prot: TPM4_HUMAN, P67936 Tissue specificity : Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecularweight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level) SABiosciences Expression via Pathway-Focused PCR Array including TPM4 : Osmotic Stress in human mouse rat
Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPM4
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Orthologsfor TPM4 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for TPM4 gene from 6/20 species (see all 20 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Tpm45
tropomyosin 4
--
8 (34.81 cM) 72134975
lizard Reptilia TPM16 6
--
60(a) 59(a)
possible orthologpossible ortholog
AAWZ02037793(3041-7823) GL344238.1(6337-9084)
African clawed frog Amphibia L35238.12
--
80.05(n)
L35238.1
zebrafish Actinopterygii BC053144.12
--
75.95(n)
BC053144.1
fruit fly Insecta Tm26 6
Tropomyosin 1
45(a) 19(a)
possible orthologpossible ortholog
3R(11135915-11140919) 3R(11107093-11134501)
worm Secernentea lev-116
Tropomyosin isoforms a/b/d/f
55(a)
possible ortholog
I(14620748-14631243)
ENSEMBL Gene Tree for TPM4 (if available)TreeFam Gene Tree for TPM4 (if available)
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Paralogsfor TPM4 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TPM4 gene TPM3 2 TPM1 2 TPM2 2 6 SIMAP similar genes for TPM4 using alignment to 10 protein entries: TPM4_HUMAN (see all proteins ):TPM1 TPM2 TPM3 TPM2b OK/SW-cl.5 DKFZp686J1372 About GeneDecksing
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Genomic Variantsfor TPM4 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 19 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for TPM4 (16177831 - 16213813 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for TPM4 1 CNV 5942
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor TPM4 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 600317
OMIM disorders : --13 : About MalaCards inflammatory myofibroblastic tumor hypertrophic cardiomyopathy familial hypertrophic cardiomyopathy esophageal squamous cell carcinoma squamous cell carcinoma cardiomyopathy vaginal cancer esophagitis vaginitis esophageal cancer hypertension carcinoma schizophrenia 1 disease from the University of Copenhagen DISEASES database for TPM4 :Anaplastic large cell lymphoma Export disorders for TPM4 gene to outside databases
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Publicationsfor TPM4 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TPM4 gene, integrated from 9 sources (see all 44 ):(articles sorted by number of sources associating them with TPM4) Utopia : connect your pdf to the dynamic
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801) 1 , 2 (2003) Assignment of the human alpha-tropomyosin gene TPM4 to band 19p13.1 by fluorescence in situ hybridization. (PubMed id 8641132) 1 , 3(1996) Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667) 1 , 2 (1992) The calcium binding protein tropomyosin in human platelets and cardiac tissue: elevation in hypertensive cardiac hypertrophy. (PubMed id 1836432) 1 , 2 (1991) Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin. (PubMed id 3612796) 1 , 2 (1987) A muscle-type tropomyosin in human fibroblasts: evidence for expression by an alternative RNA splicing mechanism. (PubMed id 3865200) 1 , 2 (1985) A census of human soluble protein complexes. (PubMed id 22939629) 1 (2012) Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860) 1 (2012)
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External Searches for TPM4 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TPM4 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TPM4 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TPM4 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for TPM4 gene: TPM4 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TPM4 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for TPM4 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for TPM4 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for TPM4 OriGene 3'-UTR Clone for TPM4 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for TPM4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for TPM4 OriGene Custom Protein Services for TPM4 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TPM4 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
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TPM4 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPM4
Search ThermoFisher Antibodies for TPM4
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TPM4
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Microarrays
In-situ hybridization
