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TPGS2 Gene

protein-coding   GIFtS: 41
GCID: GC18M034359

Tubulin Polyglutamylase Complex Subunit 2

(Previous name: chromosome 18 open reading frame 10)
(Previous symbol: C18orf10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tubulin Polyglutamylase Complex Subunit 21 2
C18orf101 2 3
PGs22 3
Chromosome 18 Open Reading Frame 101
L172

External Ids:    HGNC: 245611   Entrez Gene: 259412   Ensembl: ENSG000001347797   UniProtKB: Q68CL53   

Export aliases for TPGS2 gene to outside databases

Previous GC identifer: GC18M034377


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TPGS2 Gene:
This gene encodes a protein that is a component of the neuronal polyglutamylase complex, which plays a role in
post-translational addition of glutamate residues to C-terminal tubulin tails. Alternatively spliced transcript
variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Dec 2012)

GeneCards Summary for TPGS2 Gene:
TPGS2 (tubulin polyglutamylase complex subunit 2) is a protein-coding gene. Diseases associated with TPGS2 include hepatoblastoma, and neuronitis.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000018.10  NT_010966.15  NC_018929.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TPGS2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTPGS2 promoter sequence
   Search Chromatin IP Primers for TPGS2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TPGS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12.2   Ensembl cytogenetic band:  18q12.2   HGNC cytogenetic band: 18q12.2

TPGS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TPGS2 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M034359:  view genomic region     (about GC identifiers)

Start:
34,359,987 bp from pter      End:
34,409,158 bp from pter
Size:
49,172 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TPGS2_HUMAN, Q68CL5 (See protein sequence)
Recommended Name: Tubulin polyglutamylase complex subunit 2  
Size: 300 amino acids; 33318 Da
Subunit: Part of the neuronal tubulin polyglutamylase complex which contains TPGS1, TPGS2, TTLL1, LRRC49 and NICN1
(By similarity)
Sequence caution: Sequence=AAH22199.2; Type=Erroneous initiation; Sequence=CAB43322.2; Type=Erroneous initiation;
Secondary accessions: Q4KN59 Q8WTU3 Q96BT9 Q9Y435
Alternative splicing: 3 isoforms:  Q68CL5-2   Q68CL5-1   Q68CL5-3   

Explore the universe of human proteins at neXtProt for TPGS2: NX_Q68CL5

Explore proteomics data for TPGS2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TPGS2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (9 alternative transcripts): 
    NP_001258878.1  NP_001258879.1  NP_001258880.1  NP_001258881.1  NP_001258882.1  NP_001258883.1  NP_001258884.1  NP_001258885.1  
    NP_056291.2  

    ENSEMBL proteins: 
     ENSP00000465551   ENSP00000468292   ENSP00000464780   ENSP00000467204   ENSP00000335144  
     ENSP00000467392   ENSP00000372530   ENSP00000466973   ENSP00000467163   ENSP00000465987  
     ENSP00000467995   ENSP00000466788   ENSP00000465449   ENSP00000465090  

    TPGS2 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TPGS2
    Browse Proteins at Cloud-Clone Corp.

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR018958 SMI1/KNR4_like_dom

    Graphical View of Domain Structure for InterPro Entry Q68CL5

    ProtoNet protein and cluster: Q68CL5


    TPGS2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 MGI phenotypic allele for Tpgs2 (no phenotypes)

    TPGS2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tpgs2tm1(KOMP)Vlcg for TPGS2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TPGS2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TPGS2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TPGS2

    miRNA
    Products:
        
    miRTarBase miRNAs that target TPGS2:
    hsa-mir-148b-3p (MIRT019452), hsa-mir-7-5p (MIRT025881), hsa-mir-423-5p (MIRT038092), hsa-mir-192-5p (MIRT026690), hsa-mir-19b-3p (MIRT050628), hsa-mir-26a-5p (MIRT050148)

    Block miRNA regulation of human, mouse, rat TPGS2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TPGS2
    SwitchGear 3'UTR luciferase reporter plasmidTPGS2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TPGS2

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPGS2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPGS2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TPGS2_HUMAN, Q68CL5: Cytoplasm, cytoskeleton (By similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005874microtubule IEA--

    TPGS2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TPGS2
    Interactions:

        Search GeneGlobe Interaction Network for TPGS2

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for TPGS2 (Q68CL53 ENSP000003351444) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EWSR1Q018443, ENSP000003810314I2D: score=3 STRING: ENSP00000381031
    HDGFENSP000003571894STRING: ENSP00000357189
    TPGS1ENSP000003522654STRING: ENSP00000352265
    UBCENSP000003448184STRING: ENSP00000344818
    --Q96MX43I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TPGS2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TPGS2 gene (9 alternative transcripts): 
    NM_001271949.1  NM_001271950.1  NM_001271951.1  NM_001271952.1  NM_001271953.1  NM_001271954.1  NM_001271955.1  NM_001271956.1  
    NM_015476.3  

    Unigene Cluster for TPGS2:

    Tubulin polyglutamylase complex subunit 2
    Hs.436636  [show with all ESTs]
    Unigene Representative Sequence: NM_015476
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000590652 ENST00000590258 ENST00000587129 ENST00000591906 ENST00000590842
    ENST00000587382 ENST00000334295(uc002kzw.1 uc010xci.1 uc002kzx.1 uc002kzy.3)
    ENST00000593035 ENST00000383056 ENST00000590500 ENST00000589049 ENST00000591823
    ENST00000585635 ENST00000590692 ENST00000590337 ENST00000587511 ENST00000587207
    ENST00000591648
    miRNA
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    Block miRNA regulation of human, mouse, rat TPGS2 using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidTPGS2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TPGS2
    Predesigned siRNA for gene silencing in human, mouse, rat TPGS2
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    GenScript Custom all cDNA clones Services for TPGS2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TPGS2
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat TPGS2
      QuantiFast Probe-based Assays in human, mouse, rat TPGS2

    Additional mRNA sequence: 

    AB073382.1 AK000543.1 AK295817.1 AL050225.1 AY598336.1 BC015178.1 BC022199.2 BC087845.1 

    Selected DOTS entries (see all 31):

    DT.100728708  DT.100651787  DT.99954251  DT.100847111  DT.100651785  DT.95162176  DT.95162177  DT.91759811 
    DT.444884  DT.99962060  DT.121104226  DT.91759809  DT.100854110  DT.121104315  DT.100685908  DT.75197959 
    DT.91759793  DT.40218507  DT.95162175  DT.121104264  DT.97799371  DT.108195  DT.121104184  DT.95162165 

    Selected AceView cDNA sequences (see all 474):

    AW170424 AA676829 BQ054248 AW952016 CR618149 BI087087 AI478855 BE465347 
    AI871608 BM671368 CA443024 BF970744 BX340466 BQ957216 AI459173 AW473069 
    CR614442 CR620916 W92357 AY598336 AI915299 AA535617 CR622100 BM982306 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TPGS2 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i · 1j ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10a ·
    SP1:                                                              -     -                 -     -                 -     -                                       
    SP2:                                                                    -                 -     -                 -     -                                       
    SP3:                                                              -     -                 -     -                 -     -     -     -     -     -               
    SP4:                                                              -     -                 -     -                 -     -                                       
    SP5:                                                                    -                 -     -           -     -     -     -                                 

    ExUns: 10b · 10c ^ 11
    SP1:  -     -         
    SP2:                  
    SP3:  -     -         
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for TPGS2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TPGS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAACCTCTCA
    TPGS2 Expression
    About this image

    TPGS2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TPGS2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.436636
        Custom PCR Arrays for TPGS2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPGS2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TPGS2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tpgs21 , 5 RIKEN cDNA 5730494M16 gene5
    tubulin polyglutamylase complex subunit 21
    88.44(n)1
    88.19(a)1
      18 (13.69 cM)5
    666481  NM_001004361.21  NP_001004361.21 
     251272235 
    chicken
    (Gallus gallus)
    Aves C18ORF101 chromosome Z open reading frame, human C18orf10 73.01(n)
    75.75(a)
      426891  XM_004937079.1  XP_004937136.1 
    lizard
    (Anolis carolinensis)
    Reptilia TPGS26
    tubulin polyglutamylase complex subunit 2
    69(a)
    1 ↔ 1
    GL343372.1(385732-405685)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tpgs21 tubulin polyglutamylase complex subunit 2 68.91(n)
    66.8(a)
      549644  NM_001016890.2  NP_001016890.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tpgs21 tubulin polyglutamylase complex subunit 2 61.52(n)
    58.69(a)
      431755  NM_001002208.1  NP_001002208.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG69311 CG6931 46.53(n)
    34.16(a)
      39363  NM_140279.3  NP_648536.1 


    ENSEMBL Gene Tree for TPGS2 (if available)
    TreeFam Gene Tree for TPGS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TPGS2 (see all 804)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1908169641,2
    --34360549(+) GATATC/TATAGA 1 -- int10--------
    rs1413752521,2
    --34360553(+) TTATAA/GACTAT 1 -- int10--------
    rs1140463711,2
    F--34360684(+) ACAGCG/AGTATT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1150734661,2
    F--34360764(+) CCTCTA/GTAGGG 1 -- int11Minor allele frequency- G:0.02WA 118
    rs1474277911,2
    --34361102(+) GATGGA/GAAGGC 1 -- int10--------
    rs771855761,2
    F--34361178(+) ACCCTC/TCACGG 1 -- int11Minor allele frequency- T:0.01WA 118
    rs1135100211,2
    C,F--34361182(+) TCCACG/AGAAGC 1 -- int11Minor allele frequency- A:0.50NA 2
    rs728835471,2
    C,F--34361227(+) AACCTC/TTGTCT 1 -- int12Minor allele frequency- T:0.20WA NA 122
    rs1381308091,2
    C--34361338(+) TAGGCC/TGGGTG 1 -- int10--------
    rs1436017771,2
    --34361339(+) AGGCCA/GGGTGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for TPGS2 (34359987 - 34409158 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TPGS2: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TPGS2
    DNA2.0 Custom Variant and Variant Library Synthesis for TPGS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for TPGS2:    
    About MalaCards
    hepatoblastoma    neuronitis    lung cancer    obesity
    malaria


    TPGS2 for disorders           About GeneDecksing


    Export disorders for TPGS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TPGS2 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with TPGS2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (Oncogene 2004)
    2. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (Oncogene 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Tubulin polyglutamylase enzymes are members of the TTL domain protein family. (PubMed id 15890843)1 Janke C.... Edde B. (Science 2005)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25941 HGNC: 24561 AceView: C18orf10 Ensembl:ENSG00000134779 euGenes: HUgn25941
    ECgene: TPGS2 H-InvDB: TPGS2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TPGS2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TPGS2 gene:
    Search GeneIP for patents involving TPGS2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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