External Ids for TPD52L1 Gene
Previous GeneCards Identifiers for TPD52L1 Gene
This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed, but the full-length nature of some variants has not yet been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for TPD52L1 Gene
TPD52L1 (Tumor Protein D52-Like 1) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and Clathrin derived vesicle budding. GO annotations related to this gene include protein homodimerization activity and protein heterodimerization activity. An important paralog of this gene is TPD52L3.