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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TPD52L1 Gene

protein-coding   GIFtS: 59
GCID: GC06P125516

tumor protein D52-like 1
 Explore 6 diseases affiliated with
TPD52L1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TPD52L1    

Aliases
for TPD52L1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tumor Protein D52-Like 11 2 3
HD531
D531 2
Tumor Protein D532

External Ids:    HGNC: 120061   Entrez Gene: 71642   Ensembl: ENSG000001119077   OMIM: 6040695   UniProtKB: Q168903   

Export aliases for TPD52L1 gene to outside databases

Previous GC identifers: GC06P125134 GC06P125322 GC06P125455 GC06P123051


Summaries
for TPD52L1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TPD52L1:
This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain
and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell
proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5
(MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants
have been observed, but the full-length nature of some variants has not yet been determined. (provided by RefSeq, Jul
2008)

Gene Wiki entry for TPD52L1


Genomic Views
for TPD52L1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TPD52L1 gene promoter:
         TBP   RFX1   E2F-1   E2F   TFIID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): TPD52L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TPD52L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TPD52L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22-q23   Ensembl cytogenetic band:  6q22.31   HGNC cytogenetic band: 6q22-q23

TPD52L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TPD52L1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P125516:  view genomic region     (about GC identifiers)

Start:
 125,440,195 bp from pter      End:
 125,585,553 bp from pter
Size:
 145,359 bases      Orientation:
 plus strand

Proteins
for TPD52L1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TPD53_HUMAN, Q16890 (See protein sequence)
Recommended Name: Tumor protein D53  
Size: 204 amino acids; 22449 Da
Subunit: Forms a homodimer or heterodimer with other members of the family
Sequence caution: Sequence=AAC98475.1; Type=Erroneous initiation;
Secondary accessions: A8K757 A8K772 A8MUD2 A8MUJ7 A8MW70 O43397 Q5TC99 Q5TDQ0 Q9BUQ6 Q9C054
Alternative splicing: 4 isoforms:  Q16890-1   Q16890-2   Q16890-3   Q16890-4   

Explore the universe of human proteins at neXtProt for TPD52L1: NX_Q16890

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16890

    • TPD52L1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001003395.1  NP_001003396.1  NP_001003397.1  NP_003278.1  

    ENSEMBL proteins: 
     ENSP00000432806   ENSP00000306285   ENSP00000434142   ENSP00000357387   ENSP00000357373  
     ENSP00000436953   ENSP00000434743   ENSP00000435447   ENSP00000432590   ENSP00000376273  
     ENSP00000432787  
    Reactome Protein details: Q16890
    Human Recombinant Protein Products: 
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    Novus Biologicals TPD52L1 Proteins
    Novus Biologicals TPD52L1 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for TPD52L1
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA12963375
    GO:0048471perinuclear region of cytoplasm IDA12963375


    TPD52L1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for TPD52L1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TPD52L1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007327 TPD52

    Graphical View of Domain Structure for InterPro Entry Q16890

    ProtoNet protein and cluster: Q16890

    1 Blocks protein family: IPB007327 Tumor protein D52

    UniProtKB/Swiss-Prot: TPD53_HUMAN, Q16890
    Similarity: Belongs to the TPD52 family


    Function
    for TPD52L1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for TPD52L1:
    tumor protein D52-like 1,breast carcinoma associated (hD53)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: TPD52L1 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: TPD52L1
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    Gene Editing
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    Clone
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    Cell Line
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    LifeMap BioReagents: cell line associated with TPD52L1: PureStem ES-210, Ecto-ntu Progenitor

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TPD52L1

    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI9484778
    GO:0008656cysteine-type endopeptidase activator activity involved in apoptotic process IDA14761963
    GO:0042802identical protein binding IPI9484778
    GO:0042803protein homodimerization activity IDA9484778
    GO:0046982protein heterodimerization activity IDA9484778


    TPD52L1 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for TPD52L1:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 


    Pathways & Interactions
    for TPD52L1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Clathrin derived vesicle budding
    		trans-Golgi Network Vesicle Budding1.00
    		Golgi Associated Vesicle Biogenesis0.89
    		Clathrin derived vesicle budding1.00
    2Membrane Trafficking
    		Membrane Trafficking1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for TPD52L1
        Membrane Trafficking
    Clathrin derived vesicle budding
    Golgi Associated Vesicle Biogenesis
    trans-Golgi Network Vesicle Budding



    TPD52L1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TPD52L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/24 Interacting proteins for TPD52L1 (Q168901, 2, 3 ENSP000003573874) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TPD52P553271, 3, ENSP000003683914EBI-782694,EBI-782581 I2D: score=4 STRING: ENSP00000368391
    SFNP319472, 3, ENSP000003409894MINT-8009280 I2D: score=1 STRING: ENSP00000340989
    EIF3JO758222, 3MINT-63144 I2D: score=5 
    GPR135Q8IZ082, 3MINT-63146 I2D: score=5 
    YAE1D1Q9NRH12, 3MINT-63147 I2D: score=5 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle IDA16112108
    GO:0006309apoptotic DNA fragmentation IDA14761963
    GO:0006917induction of apoptosis IDA14761963
    GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process IDA14761963
    GO:0043406positive regulation of MAP kinase activity IDA14761963


    TPD52L1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TPD52L1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TPD52L1
    Search CenterWatch for drugs/clinical trials and news about TPD52L1 / TPD53 

    Transcripts
    for TPD52L1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TPD52L1 gene (4 alternative transcripts): 
    NM_001003395.1  NM_001003396.1  NM_001003397.1  NM_003287.2  

    Unigene Cluster for TPD52L1:

    Tumor protein D52-like 1
    Hs.591347  [show with all ESTs]
    Unigene Representative Sequence: U44429
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000534368 ENST00000304877 ENST00000534000(uc003pzu.1 uc003pzv.1 uc003pzw.1 uc003pzy.1)
    ENST00000368402 ENST00000368388 ENST00000527711 ENST00000392483 ENST00000528193
    ENST00000532978(uc003pzx.1) ENST00000532429 ENST00000534199 ENST00000392482(uc003pzz.1)
    ENST00000524679 ENST00000532423 ENST00000530868 ENST00000576089 ENST00000571678


    miRNA
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    hsa-miR-513b hsa-miR-302f
    SwitchGear 3'UTR luciferase reporter plasmid: TPD52L1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TPD52L1 (see all 7)
    OriGene shRNA RFP: TPD52L1
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    Clone
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    Additional cDNA sequence: 

    AF004427.1 AF208012.1 AK291866.1 AK291872.1 AK291887.1 BC002375.2 U44427.1 U44428.1 
    U44429.1 

    20 DOTS entries:

    DT.100029626  DT.91750623  DT.100792704  DT.91750618  DT.100792694  DT.443882  DT.121377137  DT.121377141 
    DT.100029625  DT.91800395  DT.121377146  DT.75173596  DT.91750616  DT.91750625  DT.92024401  DT.99971140 
    DT.102822250  DT.121377151  DT.95317525  DT.95317532 

    24/171 AceView cDNA sequences (see all 171):

    BM913790 AI276300 CB160306 F32726 AA745950 AA723205 BG163416 NM_001003397 
    AL120549 BC002375 AW513729 AW118159 BM702144 AI620933 AA523855 AI185226 
    BF725814 AI370762 BE207625 AA621783 AW243683 BE045833 AA948661 AI215598 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for TPD52L1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g
    SP1:                    -     -     -     -     -           -                 -     -                 -                                             
    SP2:                    -     -     -     -     -           -                 -     -     -           -                                             
    SP3:                                      -     -           -                 -     -                                                               
    SP4:                                                        -                 -     -                                                               
    SP5:                    -     -     -     -     -           -                 -     -     -     -     -                                             


    ECgene alternative splicing isoforms for TPD52L1

    Expression
    for TPD52L1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TPD52L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACTGTCTCCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TPD52L1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
    BrainChoroid PlexusBrain
    BrainMedulla OblongataBrain
    Neural TubeDiencephalic Roof PlateNeural Tube
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)Intermediate Mesoderm, Kidney
    PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    Primitive gut tube-like cells (A scalable, suspensi...)

    See TPD52L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TPD52L1

    SOURCE GeneReport for Unigene cluster: Hs.591347
        SABiosciences Expression via Pathway-Focused PCR Array including TPD52L1: 
              Apoptosis 384HT in human mouse rat

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    In Situ
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    Orthologs
    for TPD52L1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TPD52L1 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TPD52L11 tumor protein D52-like 1 78.43(n)
    83.82(a)    		   374049  NM_204215.1  NP_989546.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TPD52L16
    		 --
    		 73(a)
    		 1 ↔ 1
    		 1(180754865-180776200)
    zebrafish
    (Danio rerio)    		 Actinopterygii BQ093893.12   -- 76.48(n)    BQ093893.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG51746
    		 --
    		 13(a)
    		 1 → many
    		 2R(14308915-14313732)
    worm
    (Caenorhabditis elegans)    		 Secernentea F13E6.16
    		 Uncharacterized protein F13E6.1
    		 24(a)
    		 1 → many
    		 X(10675636-10677048)


    ENSEMBL Gene Tree for TPD52L1 (if available)
    TreeFam Gene Tree for TPD52L1 (if available) 

    Paralogs
    for TPD52L1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TPD52L1 gene
    TPD52L32  TPD52L22  TPD522  
    6 SIMAP similar genes for TPD52L1 using alignment to 6 protein entries:     TPD53_HUMAN (see all proteins):
    hD53    TPD52    PrLZ    DKFZp686A1765    TPD52L3    TPD52L2

    TPD52L1 for paralogs           About GeneDecksing



    Genomic Variants
    for TPD52L1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2077 NCBI SNPs in TPD52L1 are shown (see all 2077)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1151541201,2
    		C,F,--123050298(+) TAAGAC/TTTACT 4 -- us2k11Minor allele frequency- T:0.02WA 118
    rs557360981,2
    		C,--123051422(+) CCTTAT/CAGCGC 4 -- us2k13Minor allele frequency- C:0.04WA NA 240
    rs735717581,2
    		C,--123052438(+) ATCTTG/AGGGTC 4 -- int12Minor allele frequency- A:0.06WA 120
    rs590612991,2
    		C,--123052983(+) GTCAGG/ATTGGA 4 -- int12Minor allele frequency- A:0.18WA 120
    rs37784661,2
    		C,--123053071(-) TGAAGA/GCTCTC 4 -- int10--------
    rs624314351,2
    		--123054405(+) TGGTGC/AGTGCC 4 -- int11Minor allele frequency- A:0.50NA 2
    rs37997801,2
    		C,--123055047(-) ATGTCC/TATAAC 4 -- int14Minor allele frequency- T:0.12WA NA EA 360
    rs94826051,2
    		C,F,--123055225(+) TATGGG/ATGGAG 4 -- int13Minor allele frequency- A:0.20WA CSA 122
    rs38395521,2
    		C,--123055330(-) TGTCT-/TAAAGC 4 -- int10--------
    rs624321841,2
    		C,--123055470(+) TAACTT/ATGTTG 4 -- int11Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for TPD52L1 (125440195 - 125585553 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TPD52L1: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for TPD52L1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TPD52L1 for disorders           About GeneDecksing

    OMIM gene information: 604069    OMIM disorders: --

    6 diseases for TPD52L1:    About MalaCards
    collecting duct carcinoma    childhood leukemia    breast carcinoma    breast cancer
    carcinoma    leukemia

    3 Novoseek disease relationships for TPD52L1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    breast carcinoma 64.6 10 12963375 (2), 9838088 (1), 16112108 (1), 9484778 (1) (see all 6)
    tumors 22.3 9 15489060 (1), 16112108 (1), 8812487 (1), 9730602 (1)
    breast cancer 21 6 16112108 (3), 18698023 (1)


    Export disorders for TPD52L1 gene to outside databases

    Publications
    for TPD52L1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TPD52L1 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with TPD52L1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52). (PubMed id 8812487)1, 2, 3, 9 Byrne J.A.... Basset P. (1996)
    2. D53 (TPD52L1) is a cell cycle-regulated protein maximally expressed at the G2-M transition in breast cancer cells. (PubMed id 16112108)1, 3, 9 Boutros R. and Byrne J.A. (2005)
    3. Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system. (PubMed id 9484778)1, 2, 9 Byrne J.A.... Gunning P. (1998)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Identification and in situ hybridization mapping of a mouse Tpd52l1 (D53) orthologue to chromosome 10A4-B2. (PubMed id 9730602)1, 9 Byrne J.A....Gunning P. (1998)
    6. Alternative splicing as a mechanism for regulating 14-3-3 binding: interactions between hD53 (TPD52L1) and 14-3-3 proteins. (PubMed id 12963375)1, 9 Boutros R....Byrne J.A. (2003)
    7. A testis-specific and testis developmentally regulated tumor protein D52 (TPD52)-like protein TPD52L3/hD55 interacts with TPD52 family proteins. (PubMed id 16631610)1, 9 Cao Q.... Li J. (2006)
    8. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)

    External Searches for TPD52L1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing TPD52L1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7164 HGNC: 12006 AceView: TPD52L1 Ensembl:ENSG00000111907 euGenes: HUgn7164
    ECgene: TPD52L1 H-InvDB: TPD52L1

    Other Databases showing TPD52L1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TPD52L1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TPD52L1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TPD52L1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for TPD52L1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TPD52L1 gene:
    Search GeneIP for patents involving TPD52L1

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