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TPD52 Gene

protein-coding GIFtS: 59

GC08M081110

tumor protein D52
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
D52 ^¹, ²
N8L ^¹, ²
PC-1 ^²
PrLZ ^²
hD52 ^¹, ²

Descriptions
Protein N8 ^³
prostate and colon associated protein ^²
tumor protein D52 ^²

External Ids
HGNC: 12005¹
Entrez Gene: 7163²
UniProtKB: P55327³
Ensembl: ENSG00000076554⁷

Search outside databases for aliases for TPD52 gene

Previous GC identifers: GC08M079835 GC08M080995 GC08M080670 GC08M080997

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Gene Wiki entry for TPD52

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TPD52 gene

Entrez Gene cytogenetic band: 8q21 Ensembl cytogenetic band: 8q21.13 HGNC cytogenetic band: 8q21

TPD52 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M081110: (about GC identifiers)

Start:	81,109,658 bp from pter
End:	81,246,391 bp from pter
Size:	136,734 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000008.9 NT_008183.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: TPD52_HUMAN, P55327 (See protein sequence)

Recommended Name: Tumor protein D52

Size: 224 amino acids; 24327 Da

Subunit: Forms homodimer or heterodimer with other members of the family

Developmental stage: Isoform 2 is expressed at lower levels in fetal brain and kidney than in adult

brain and kidney

Secondary accessions: B7Z414 Q13056 Q53EK8 Q6FGP3 Q6FGS3 Q86YZ2 Q9UCX8

Alternative splicing: 3 isoforms: P55327-1 P55327-2 P55327-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_001020423.1 NP_001020424.1 NP_005070.1

ENSEMBL proteins:

ENSP00000368390 ENSP00000368391

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (TPD52)
	Human Recombinant Proteins from Abnova (TPD52)

OriGene Purified Recombinant Human Protein: TPD52

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IDA	15576473 16112108
GO:0005783	endoplasmic reticulum	IDA	10942595
GO:0048471	perinuclear region of cytoplasm	IDA	16112108

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Antibodies for TPD52:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for TPD52
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TPD52), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TPD52)
	Novus Biologicals Antibodies for TPD52

Assays for TPD52:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P55327

ProtoNet protein and cluster: P55327

1 Blocks protein family: IPB007327 Tumor protein D52

UniProtKB/Swiss-Prot: TPD52_HUMAN, P55327

Similarity: Belongs to the TPD52 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TPD52)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TPD52)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001025252

Applied Biosystems Silencer® siRNAs for TPD52

Sigma-Aldrich siRNA for TPD52

Sigma-Aldrich shRNA Panels and shRNA for TPD52

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TPD52
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001025252
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001025252
untagged cDNA clones in CMV expression vector (see all 3): NM_001025252

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001025252

Genatlas biochemistry entry for TPD52:

tumor protein D52,breast carcinoma associated

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IDA	15576473
GO:0042803	protein homodimerization activity	IDA	9484778
GO:0046982	protein heterodimerization activity	IDA	9484778

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for TPD52

5 Interacting proteins for TPD52 (ENSP00000368391³ P55327¹) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TPD52L1	Q16890¹	STRING (score=.878) EBI-782581, EBI-717470
TPD52	P55327¹	EBI-782581, EBI-782581
Tpd52 Tpd52 (xeno)	Q62393¹	EBI-782581, EBI-782591
MAL2	ENSP00000276681³	STRING (score=.997)
ANXA6	ENSP00000346550³	STRING (score=.97)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009653	anatomical structure morphogenesis	TAS	8632896
GO:0030183	B cell differentiation	IEP	15576473
GO:0046903	secretion	TAS	15576473

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TPD52
1 Novoseek chemical compound relationship for TPD52 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
polyacrylamide	29.84	3	9372899 (1), 15576473 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TPD52)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TPD52)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001025252

Sigma-Aldrich siRNA for TPD52

Sigma-Aldrich shRNA Panels and shRNA for TPD52

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001025252 NM_001025253 NM_005079

REFSEQ mRNAs for TPD52 gene (3 alternative transcripts):

NM_001025252.1 NM_001025253.1 NM_005079.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001025252 NM_001025253 NM_005079

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001025252
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001025252
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001025252

Additional cDNA sequence:

AF202897.1 AK057075.1 AK223631.1 AK295468.1 AK296615.1 AK308983.1 AK313135.1 BC018117.1

BT019444.1 BX640835.1 CR542034.1 CR542064.1 CR591025.1 EF152584.1 S82081.1 U18914.1

24/27 DOTS entries (see all 27 ):

DT.95261932 DT.117299 DT.95261928 DT.101969586 DT.120648588 DT.120648556 DT.100827038 DT.434112

DT.120648567 DT.120648587 DT.120648511 DT.120648620 DT.91885426 DT.95261926 DT.95261930 DT.101974971

DT.120648621 DT.75118581 DT.95315786 DT.100030168 DT.120648523 DT.91683132 DT.95261925 DT.95290503

24/383 AceView cDNA sequences (see all 383 ):

BU162860 BQ687427 AI922688 CB177973 BI600172 AA306002 BM667273 BE220007

AU076702 BU783828 BQ690015 BM927243 AI334712 BM661688 BI599347 BU157039

AA505975 AW135527 CB991297 CA943102 AA761317 BQ878165 BU158728 AW117230

highest scoring ESTs for TPD52:

U18914 AA377036 AI632972 AV708387 AV728041 BC018117 BE884342 BE890337 BG339306 BG703216

Unigene Cluster for TPD52:

Tumor protein D52

Hs.368433 [show with all ESTs]

Unigene Representative Sequence: NM_001025252

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for TPD52 (see all 12 )

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	^	6a	·	6b	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13a	·	13b	·	13c	·	13d	·	13e	·	13f	·	13g	·	13h
SP1:					-		-		-		-		-										-		-				-
SP2:					-		-		-		-		-										-		-				-		-		-
SP3:					-		-		-		-		-		-								-		-				-		-		-
SP4:											-		-										-		-				-		-		-
SP5:																							-		-				-		-		-

About this scheme

ECgene alternative splicing isoforms for TPD52

2 Ensembl transcripts including schematic representations:

ENST00000379096 ENST00000379097

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TPD52 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TPD52

¹ / ² / ³

16 probe-sets matching TPD52 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
81733_at²^{, 3}	U95-E	1	1.00	1.00	0.92	1.10	AI632972	0.80	1.00	0.91	1
33840_at²^{, 3}	U95-A	1	1.00	1.00	0.86	0.82	U18914	1.00	1.00	1.00	1
53106_at²	U95-B	2	0.88	0.50	-0.08	1.56	--	--	--	--	--
86423_at²	U95-D	1	0.38	1.00	0.16	0.59	--	--	--	--	--
201688_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BG389015	0.60	1.00	0.82	1
201691_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005079	0.60	1.00	0.82	1
201689_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BE974098	0.60	1.00	0.82	1
201690_s_at²^{, 3}	U133-A	2	1.00	0.95	--	--	AA524023	0.60	1.00	0.82	1
236655_at²^{, 3}	U133-B	1	0.91	1.00	--	--	AI632972	0.80	1.00	0.91	1
219819_s_at²	U133-A	2	0.82	0.41	--	--	--	--	--	--	--
201688_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201691_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201689_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201690_s_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--
236655_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--
219819_s_at²	U133Plus2	2	0.82	0.41	--	--	--	--	--	--	--

GeneDecks TPD52 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGAAAAGCTT

SOURCE GeneReport for Unigene cluster: Hs.368433
Expression variation in blood from EXPOLDB for TPD52
UniProtKB/Swiss-Prot: TPD52_HUMAN, P55327
Tissue specificity: Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor
cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and
pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at
very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for TPD52 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TPD52¹	--	tumor protein D52	91.75(n) 96.04(a)	477920 XM_535110.2 XP_535110.2
chimpanzee (Pan troglodytes)	TPD52¹	--	tumor protein D52	99.84(n) 99.52(a)	748737 XM_001162922.1 XP_001162922.1
rat (Rattus norvegicus)	Tpd52¹	--	tumor protein D52	86.17(n) 90.5(a)	294900 XM_215524.4 XP_215524.4
mouse (Mus musculus)	Tpd52⁵	3	tumor protein D52	--	U44426
chicken (Gallus gallus)	TPD52¹	--	tumor protein D52	79.5(n) 87.5(a)	770339 XM_001233679.1 XP_001233680.1

About this table Species with no ortholog for TPD52

ENSEMBL Gene Tree for TPD52

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for TPD52 gene

TPD52L3² TPD52L2² TPD52L1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/934 NCBI SNPs in TPD52 are shown (see all 934 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 228)

AB	SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs6473210^1,2	A,C,F,H	81246849(+)	`AGAATC/ATCTTG`	2	--	ng3¹		3		EA WA	298
	rs10098470^1,2	A,C,F,H	81111833(+)	`TTACAG/ATTTCC`	3	--	ut3¹		8		EU EA WA	836
	rs10092517^1,2	A,C,F,H	81157516(+)	`CCCTGA/CCAGGC`	3	--	ng3¹ int¹		4		EU EA WA	418
	rs17459080^1,2	C,F,H	81157356(+)	`TACATC/TCATGT`	3	--	ng3¹ int¹		15		NA EU EA WA	1398
	rs16907441^1,2	C,F,H	81156033(+)	`AGCTCA/CCGGGT`	3	--	ng3¹ int¹		12		NA EU EA WA	1056
--	rs3217285^1,2	C,F	81156159(-)	`TAAAT-/AAGGA AATAAATTTGGT`	3	--	ng3¹ int¹		5		EU EA NA MN	430
	rs6983341^1,2	F,H	81155685(+)	`GACCAT/CGACTA`	3	--	ng3¹ int¹		4		EU EA WA	420
	rs7017645^1,2	A,H	81246538(+)	`CGGGAG/AGAGGG`	2	--	ng3¹ trp³		4		EU EA WA	384
--	rs10111451^1,2	A,C	81246415(+)	`TTTCCC/TGGGGC`	2	--	ng3¹ ese³		0	--	--	--	--
--	rs11542215^1,2	C,H	81128117(-)	`ACTAAA/GACAGA`	3	K/R	mis¹		8		EU EA WA	808

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HapMap Linkage Disequilibrium images for TPD52 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604068

8 Novoseek disease relationships for TPD52 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
breast carcinoma	53.23	20	10918393 (5), 18698023 (2), 9484778 (2), 9838088 (1) (see all 5)
prostate cancer	53.16	33	17418805 (5), 15172988 (5), 14996714 (5), 16159422 (4) (see all 9)
tumors	37.03	64	15986428 (3), 12526213 (3), 18698023 (3), 18959755 (2) (see all 22)
breast cancer	27.22	11	18698023 (2), 12747765 (2), 18959755 (1), 17487680 (1) (see all 7)
benign prostatic hyperplasia	26.31	1	9372899 (1)
cancer	21.86	13	18698023 (2), 12526213 (1), 19105569 (1), 10918393 (1) (see all 5)
ovarian cancer	13.74	4	15986428 (2)
metastasis	12.31	4	17314271 (1), 12526213 (1), 17962942 (1)

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1 PharmGKB disease relationship for TPD52 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12730115

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/53 PubMed articles for TPD52 gene (see all 53 ):

A screening method to identify genes commonly overexpressed in carcinomas and the identification of a novel complementary DNA sequence. (PubMed id 7796418)^{2, 3, 4} Byrne J.A.... Basset P. (1995)
PrLZ, a novel prostate-specific and androgen-responsive gene of the TPD52 family, amplified in chromosome 8q21.1 and overexpressed in human prostate cancer. (PubMed id 14996714)^{1, 3, 4} Wang R.... Chung L.W. (2004)
Identification of homo- and heteromeric interactions between members of the breast carcinoma-associated D52 protein family using the yeast two-hybrid system. (PubMed id 9484778)^{1, 3, 4} Byrne J.A.... Gunning P. (1998)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Isolation and characterization of a novel gene expressed in multiple cancers. (PubMed id 8632896)^{3, 4} Chen S.L.... Bhat N.K. (1996)
Definition of the tumor protein D52 (TPD52) gene family through cloning of D52 homologues in human (hD53) and mouse (mD52). (PubMed id 8812487)^{1, 3} Byrne J.A.... Basset P. (1996)
Tumor protein D52 (TPD52) is overexpressed and a gene amplification target in ovarian cancer. (PubMed id 15986428)^{1, 3} Byrne J.A....Defazio A. (2005)
Nonredundant functions for tumor protein D52-like proteins support specific targeting of TPD52. (PubMed id 18698023)^{1, 3} Shehata M....Byrne J.A. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 7163	HGNC: 12005	AceView: TPD52	Ensembl:ENSG00000076554	euGenes: HUgn7163
ECgene: TPD52	H-InvDB: TPD52

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for TPD52	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for TPD52
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for TPD52:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TPD52-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TPD52		Antibodies for TPD52
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TPD52		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (TPD52)
	Antibodies (TPD52)
	Chimera RNAi (TPD52)
	Custom Service for Mouse Mab
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Antibodies for TPD52

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TPD52 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for TPD52

Summaries
for TPD52

Genomic Location
for TPD52

Proteins
for TPD52

Protein Domains/
Families
for TPD52

Gene Function
for TPD52

Pathways & Interactions
for TPD52

Drugs & Compounds
for TPD52

Transcripts
for TPD52

Expression
for TPD52

Orthologs
for TPD52

Paralogs
for TPD52

SNPs/Variants
for TPD52

Disorders & Mutations
for TPD52

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for TPD52

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Genome Databases showing TPD52

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for TPD52

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for TPD52

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TPD52 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor TPD52

Summariesfor TPD52

Genomic Locationfor TPD52

Proteinsfor TPD52

Protein Domains/Familiesfor TPD52

Gene Functionfor TPD52

Pathways & Interactionsfor TPD52

Drugs & Compoundsfor TPD52

Transcriptsfor TPD52

Expression for TPD52

Orthologsfor TPD52

Paralogsfor TPD52

SNPs/Variantsfor TPD52

Disorders & Mutationsfor TPD52

Medical Newsfor TPD52

Publicationsfor TPD52

Search for TPD52

Genome Databases showing TPD52

Other Databases showing TPD52

Specialized Databases showing TPD52

Licensable Technologiesfor TPD52

Servicesfor TPD52

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TPD52

Summaries
for TPD52

Genomic Location
for TPD52

Proteins
for TPD52

Protein Domains/
Families
for TPD52

Gene Function
for TPD52

Pathways & Interactions
for TPD52

Drugs & Compounds
for TPD52

Transcripts
for TPD52

Expression
for TPD52

Orthologs
for TPD52

Paralogs
for TPD52

SNPs/Variants
for TPD52

Disorders & Mutations
for TPD52

Medical News
for TPD52

Publications
for TPD52

Licensable Technologies
for TPD52

Services
for TPD52