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Aliases for TP73-AS1 Gene

Subcategory (RNA class) for TP73-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for TP73-AS1 Gene

  • TP73 Antisense RNA 1 2 3 4 5
  • P53-Dependent Apoptosis Modulator 2 3 4
  • KIAA0495 2 3 4
  • PDAM 3 4
  • TP73 Antisense RNA 1 (Non-Protein Coding) 3

External Ids for TP73-AS1 Gene

Previous HGNC Symbols for TP73-AS1 Gene

  • KIAA0495

Previous GeneCards Identifiers for TP73-AS1 Gene

  • GC01M003653

Summaries for TP73-AS1 Gene

GeneCards Summary for TP73-AS1 Gene

TP73-AS1 (TP73 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class.

UniProtKB/Swiss-Prot for TP73-AS1 Gene

  • May modulate apoptosis via regulation of p53/TP53-dependent anti-apoptotic genes. Induces resistance of the chemotherapy drug cisplatin in glioma cells when underexpressed.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP73-AS1 Gene

Genomics for TP73-AS1 Gene

Regulatory Elements for TP73-AS1 Gene

Enhancers for TP73-AS1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TP73-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for TP73-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TP73-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TP73-AS1 Gene

Chromosome:
1
Start:
3,735,601 bp from pter
End:
3,747,373 bp from pter
Size:
11,773 bases
Orientation:
Minus strand

Genomic View for TP73-AS1 Gene

Genes around TP73-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP73-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP73-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP73-AS1 Gene

Proteins for TP73-AS1 Gene

  • Protein details for TP73-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UF72-T73AS_HUMAN
    Recommended name:
    Putative TP73 antisense gene protein 1
    Protein Accession:
    Q9UF72

    Protein attributes for TP73-AS1 Gene

    Size:
    201 amino acids
    Molecular mass:
    20603 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene product may be present at undetectable level as Western blot analysis and immunofluorescence staining failed to detect any signals.

neXtProt entry for TP73-AS1 Gene

Proteomics data for TP73-AS1 Gene at MOPED

Post-translational modifications for TP73-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TP73-AS1 Gene

Domains & Families for TP73-AS1 Gene

Protein Domains for TP73-AS1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TP73-AS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP73-AS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TP73-AS1 Gene

Function for TP73-AS1 Gene

Molecular function for TP73-AS1 Gene

UniProtKB/Swiss-Prot Function:
May modulate apoptosis via regulation of p53/TP53-dependent anti-apoptotic genes. Induces resistance of the chemotherapy drug cisplatin in glioma cells when underexpressed.

Phenotypes for TP73-AS1 Gene

GenomeRNAi human phenotypes for TP73-AS1:
genes like me logo Genes that share phenotypes with TP73-AS1: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP73-AS1 Gene

Localization for TP73-AS1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP73-AS1 Gene

Secreted.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TP73-AS1 Gene

Pathways & Interactions for TP73-AS1 Gene

SuperPathways for TP73-AS1 Gene

No Data Available

Interacting Proteins for TP73-AS1 Gene

Gene Ontology (GO) - Biological Process for TP73-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TP73-AS1 Gene

Drugs & Compounds for TP73-AS1 Gene

No Compound Related Data Available

Transcripts for TP73-AS1 Gene

Unigene Clusters for TP73-AS1 Gene

TP73 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TP73-AS1 Gene

No ASD Table

Relevant External Links for TP73-AS1 Gene

GeneLoc Exon Structure for
TP73-AS1
ECgene alternative splicing isoforms for
TP73-AS1

Expression for TP73-AS1 Gene

mRNA expression in normal human tissues for TP73-AS1 Gene

SOURCE GeneReport for Unigene cluster for TP73-AS1 Gene Hs.49658

mRNA Expression by UniProt/SwissProt for TP73-AS1 Gene

Q9UF72-T73AS_HUMAN
Tissue specificity: Ubiquitous. Decreased expression in oligodendroglial tumors.
genes like me logo Genes that share expression patterns with TP73-AS1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TP73-AS1 Gene

Orthologs for TP73-AS1 Gene

Evolution for TP73-AS1 Gene

ENSEMBL:
Gene Tree for TP73-AS1 (if available)
TreeFam:
Gene Tree for TP73-AS1 (if available)

No data available for Orthologs for TP73-AS1 Gene

Paralogs for TP73-AS1 Gene

No data available for Paralogs for TP73-AS1 Gene

Variants for TP73-AS1 Gene

Sequence variations from dbSNP and Humsavar for TP73-AS1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs35766062 - 3,745,845(+) ATCTC(A/G)GGCCT nc-transcript-variant
rs1181863 -- 3,739,760(+) GCTGA(C/T)GACCT intron-variant, nc-transcript-variant
rs1181864 -- 3,737,626(-) TGCCA(C/T)GGCCT nc-transcript-variant
rs1181865 -- 3,736,862(-) GGAAG(A/G)TGGGG nc-transcript-variant
rs1181866 -- 3,736,848(-) GGGCT(G/T)GGCAT nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TP73-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv96n71 CNV Loss 21882294
nsv470687 CNV Loss 18288195
dgv99n71 CNV Loss 21882294
nsv871942 CNV Loss 21882294
dgv110n71 CNV Loss 21882294
nsv830314 CNV Gain+Loss 17160897
dgv13e1 CNV Complex 17122850
dgv113n71 CNV Loss 21882294
nsv460061 CNV Loss 19166990
nsv870977 CNV Loss 21882294
nsv871368 CNV Loss 21882294
nsv871021 CNV Loss 21882294
esv994567 CNV Deletion 20482838
esv2729806 CNV Deletion 23290073
nsv830425 CNV Gain 17160897
nsv871323 CNV Loss 21882294

Relevant External Links for TP73-AS1 Gene

HapMap Linkage Disequilibrium report
TP73-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TP73-AS1 Gene

Disorders for TP73-AS1 Gene

Relevant External Links for TP73-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TP73-AS1

No disorders were found for TP73-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP73-AS1 Gene

Publications for TP73-AS1 Gene

  1. KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. (PMID: 20477830) Pang J.C. … Ng H.K. (Brain Pathol. 2010) 2 3 4 67
  2. A long non-coding RNA signature in glioblastoma multiforme predicts survival. (PMID: 23726844) Zhang X.Q. … Leung G.K. (Neurobiol. Dis. 2013) 2 3
  3. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PMID: 9455484) Seki N. … Ohara O. (DNA Res. 1997) 2 3
  4. Relative expression of TAp73 and I9Np73 isoforms. (PMID: 22388545) Conforti F. … Sayan B.S. (Aging (Albany NY) 2012) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TP73-AS1 Gene

Sources for TP73-AS1 Gene

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