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Aliases for TP73-AS1 Gene

Subcategory (RNA class) for TP73-AS1 Gene

antisense

Quality Score for this RNA gene is

3

Aliases for TP73-AS1 Gene

  • TP73 Antisense RNA 1 2 3 4
  • P53-Dependent Apoptosis Modulator 2 3 4
  • KIAA0495 2 3 4
  • PDAM 3 4
  • TP73 Antisense RNA 1 (Non-Protein Coding) 3

External Ids for TP73-AS1 Gene

ORGUL Members for TP73-AS1 Gene

Previous Symbols for TP73-AS1 Gene

  • KIAA0495

Summaries for TP73-AS1 Gene

GeneCards Summary for TP73-AS1 Gene

TP73-AS1 (TP73 Antisense RNA 1) is a RNA Gene, and belongs to antisense RNA class.

UniProtKB/Swiss-Prot for TP73-AS1 Gene

  • May modulate apoptosis via regulation of p53/TP53-dependent anti-apoptotic genes. Induces resistance of the chemotherapy drug cisplatin in glioma cells when underexpressed.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP73-AS1 Gene

Genomics for TP73-AS1 Gene

Genomic Location for TP73-AS1 Gene

Start:
3,735,601 bp from pter
End:
3,747,373 bp from pter
Size:
11,773 bases
Orientation:
Minus strand

Genomic View for TP73-AS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TP73-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP73-AS1 Gene

No data available for Regulatory Elements for TP73-AS1 Gene

Proteins for TP73-AS1 Gene

  • Protein details for TP73-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UF72-T73AS_HUMAN
    Recommended name:
    Putative TP73 antisense gene protein 1
    Protein Accession:
    Q9UF72
    Secondary Accessions:

    Protein attributes for TP73-AS1 Gene

    Size:
    201 amino acids
    Molecular mass:
    20603 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene product may be present at undetectable level as Western blot analysis and immunofluorescence staining failed to detect any signals

neXtProt entry for TP73-AS1 Gene

Proteomics data for TP73-AS1 Gene at MOPED

Post-translational modifications for TP73-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TP73-AS1 Gene

Domains for TP73-AS1 Gene

Gene Families for TP73-AS1 Gene

HGNC:
  • LNCRNA :Long non-coding RNAs

Protein Domains for TP73-AS1 Gene

ProtoNet:
genes like me logo Genes that share domains with TP73-AS1: view

No data available for UniProtKB/Swiss-Prot for TP73-AS1 Gene

Function for TP73-AS1 Gene

Molecular function for TP73-AS1 Gene

UniProtKB/Swiss-Prot Function: May modulate apoptosis via regulation of p53/TP53-dependent anti-apoptotic genes. Induces resistance of the chemotherapy drug cisplatin in glioma cells when underexpressed.

Phenotypes for TP73-AS1 Gene

GenomeRNAi human phenotypes for TP73-AS1:
genes like me logo Genes that share phenotypes with TP73-AS1: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TP73-AS1 Gene

Localization for TP73-AS1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP73-AS1 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for TP73-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with TP73-AS1: view

Pathways for TP73-AS1 Gene

SuperPathways for TP73-AS1 Gene

No Data Available

Interacting Proteins for TP73-AS1 Gene

Gene Ontology (GO) - Biological Process for TP73-AS1 Gene

None

No data available for Pathways by source for TP73-AS1 Gene

Transcripts for TP73-AS1 Gene

Unigene Clusters for TP73-AS1 Gene

TP73 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TP73-AS1 Gene

No ASD Table

Relevant External Links for TP73-AS1 Gene

GeneLoc Exon Structure for
TP73-AS1
ECgene alternative splicing isoforms for
TP73-AS1

Expression for TP73-AS1 Gene

mRNA expression in normal human tissues for TP73-AS1 Gene

SOURCE GeneReport for Unigene cluster for TP73-AS1 Gene Hs.49658

mRNA Expression by UniProt/SwissProt for TP73-AS1 Gene

Q9UF72-T73AS_HUMAN
Tissue specificity: Ubiquitous. Decreased expression in oligodendroglial tumors.
genes like me logo Genes that share expressions with TP73-AS1: view

Orthologs for TP73-AS1 Gene

Evolution for TP73-AS1 Gene

ENSEMBL:
Gene Tree for TP73-AS1 (if available)
TreeFam:
Gene Tree for TP73-AS1 (if available)

No data available for Orthologs for TP73-AS1 Gene

Paralogs for TP73-AS1 Gene

No data available for Paralogs for TP73-AS1 Gene

Variants for TP73-AS1 Gene

Sequence variations from dbSNP and Humsavar for TP73-AS1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1181863 -- 3,739,760(+) GCTGA(C/T)GACCT intron-variant, nc-transcript-variant
rs1181864 -- 3,737,626(-) TGCCA(C/T)GGCCT nc-transcript-variant
rs1181865 -- 3,736,862(-) GGAAG(A/G)TGGGG nc-transcript-variant
rs1181866 -- 3,736,848(-) GGGCT(G/T)GGCAT nc-transcript-variant
rs1184732 -- 3,746,322(-) GCCAC(C/T)TGAAT nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for TP73-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv96n71 CNV Loss 21882294
nsv470687 CNV Loss 18288195
dgv99n71 CNV Loss 21882294
nsv871942 CNV Loss 21882294
dgv110n71 CNV Loss 21882294
nsv830314 CNV Gain+Loss 17160897
dgv13e1 CNV Complex 17122850
dgv113n71 CNV Loss 21882294
nsv460061 CNV Loss 19166990
nsv870977 CNV Loss 21882294
nsv871368 CNV Loss 21882294
nsv871021 CNV Loss 21882294
esv994567 CNV Deletion 20482838
esv2729806 CNV Deletion 23290073
nsv830425 CNV Gain 17160897
nsv871323 CNV Loss 21882294

Relevant External Links for TP73-AS1 Gene

HapMap Linkage Disequilibrium report
TP73-AS1

Disorders for TP73-AS1 Gene

No disorders were found for TP73-AS1 Gene.

No data available for UniProtKB/Swiss-Prot for TP73-AS1 Gene

Publications for TP73-AS1 Gene

  1. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PMID: 9455484) Seki N. … Ohara O. (DNA Res. 1997) 2 3 4
  2. KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. (PMID: 20477830) Pang J.C. … Ng H.K. (Brain Pathol. 2010) 2 3 4
  3. A long non-coding RNA signature in glioblastoma multiforme predicts survival. (PMID: 23726844) Zhang X.Q. … Leung G.K. (Neurobiol. Dis. 2013) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for TP73-AS1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate TP73-AS1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TP73-AS1
    • Block miRNA regulation of TP73-AS1 using miScript Target Protectors

    Sources for TP73-AS1 Gene

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