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Aliases for TP53TG5 Gene

Aliases for TP53TG5 Gene

  • TP53 Target 5 2 3 5
  • TP53-Inducible Gene 5 Protein 3 4
  • C20orf10 3 4
  • Chromosome 20 Open Reading Frame 10 2
  • CLG01 3

External Ids for TP53TG5 Gene

Previous HGNC Symbols for TP53TG5 Gene

  • C20orf10

Previous GeneCards Identifiers for TP53TG5 Gene

  • GC20M043436
  • GC20M044002
  • GC20M040744

Summaries for TP53TG5 Gene

GeneCards Summary for TP53TG5 Gene

TP53TG5 (TP53 Target 5) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TP53TG5 Gene

  • May play a significant role in p53/TP53-mediating signaling pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG5 Gene

Genomics for TP53TG5 Gene

Regulatory Elements for TP53TG5 Gene

Enhancers for TP53TG5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TP53TG5 on UCSC Golden Path with GeneCards custom track

Promoters for TP53TG5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TP53TG5 on UCSC Golden Path with GeneCards custom track

Genomic Location for TP53TG5 Gene

45,372,563 bp from pter
45,407,889 bp from pter
35,327 bases
Minus strand

Genomic View for TP53TG5 Gene

Genes around TP53TG5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG5 Gene

Proteins for TP53TG5 Gene

  • Protein details for TP53TG5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    TP53-target gene 5 protein
    Protein Accession:

    Protein attributes for TP53TG5 Gene

    290 amino acids
    Molecular mass:
    34019 Da
    Quaternary structure:
    • Interacts with p53/TP53.

neXtProt entry for TP53TG5 Gene

Proteomics data for TP53TG5 Gene at MOPED

Post-translational modifications for TP53TG5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TP53TG5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TP53TG5 Gene

Domains & Families for TP53TG5 Gene

Protein Domains for TP53TG5 Gene


Suggested Antigen Peptide Sequences for TP53TG5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG5: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TP53TG5 Gene

Function for TP53TG5 Gene

Molecular function for TP53TG5 Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53, UV irradiation, by hydrogen peroxide treatment or by treatment with a DNA-damaging reagent.

Phenotypes for TP53TG5 Gene

GenomeRNAi human phenotypes for TP53TG5:
genes like me logo Genes that share phenotypes with TP53TG5: view

Animal Model Products

CRISPR Products

miRNA for TP53TG5 Gene

miRTarBase miRNAs that target TP53TG5

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TP53TG5 Gene

Localization for TP53TG5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG5 Gene

Cytoplasm. Nucleus. Note=Cell cycle dependent intracellular localization.

Subcellular locations from

Jensen Localization Image for TP53TG5 Gene COMPARTMENTS Subcellular localization image for TP53TG5 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for TP53TG5 Gene

Pathways & Interactions for TP53TG5 Gene

SuperPathways for TP53TG5 Gene

No Data Available

Interacting Proteins for TP53TG5 Gene

Selected Interacting proteins: Q9Y2B4-T53G5_HUMAN for TP53TG5 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TP53TG5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030308 negative regulation of cell growth NAS 10719363
genes like me logo Genes that share ontologies with TP53TG5: view

No data available for Pathways by source and SIGNOR curated interactions for TP53TG5 Gene

Drugs & Compounds for TP53TG5 Gene

No Compound Related Data Available

Transcripts for TP53TG5 Gene

mRNA/cDNA for TP53TG5 Gene

Unigene Clusters for TP53TG5 Gene

TP53 target 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG5 Gene

No ASD Table

Relevant External Links for TP53TG5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TP53TG5 Gene

mRNA expression in normal human tissues for TP53TG5 Gene

mRNA differential expression in normal tissues according to GTEx for TP53TG5 Gene

This gene is overexpressed in Testis (x10.2), Brain - Spinal cord (cervical c-1) (x6.2), and Brain - Substantia nigra (x4.5).

Protein differential expression in normal tissues from HIPED for TP53TG5 Gene

This gene is overexpressed in Platelet (47.3) and Testis (21.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TP53TG5 Gene

SOURCE GeneReport for Unigene cluster for TP53TG5 Gene Hs.710271

mRNA Expression by UniProt/SwissProt for TP53TG5 Gene

Tissue specificity: Highly expressed in heart, brain and small intestine. Less abundant in skeletal muscle, spleen, prostate, ovary and colon. A smaller transcript is expressed specifically in the testis.
genes like me logo Genes that share expression patterns with TP53TG5: view

Protein tissue co-expression partners for TP53TG5 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for TP53TG5 Gene

Orthologs for TP53TG5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TP53TG5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TP53TG5 35
  • 76.47 (n)
  • 61.76 (a)
TP53TG5 36
  • 60 (a)
(Canis familiaris)
Mammalia TP53TG5 35
  • 77.96 (n)
  • 66.94 (a)
TP53TG5 36
  • 61 (a)
(Mus musculus)
Mammalia Trp53tg5 35
  • 71.85 (n)
  • 57.98 (a)
Trp53tg5 16
Trp53tg5 36
  • 58 (a)
(Pan troglodytes)
Mammalia TP53TG5 35
  • 99.2 (n)
  • 97.93 (a)
TP53TG5 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Tp53tg5 35
  • 71.51 (n)
  • 56.43 (a)
(Monodelphis domestica)
Mammalia TP53TG5 36
  • 39 (a)
(Ornithorhynchus anatinus)
Mammalia TP53TG5 36
  • 38 (a)
Species with no ortholog for TP53TG5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53TG5 Gene

Gene Tree for TP53TG5 (if available)
Gene Tree for TP53TG5 (if available)

Paralogs for TP53TG5 Gene

No data available for Paralogs for TP53TG5 Gene

Variants for TP53TG5 Gene

Sequence variations from dbSNP and Humsavar for TP53TG5 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
VAR_051397 -
VAR_051398 -
VAR_051399 -
VAR_051400 -
VAR_051401 -

Variation tolerance for TP53TG5 Gene

Residual Variation Intolerance Score: 91.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.65; 95.68% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TP53TG5 Gene

Disorders for TP53TG5 Gene

Relevant External Links for TP53TG5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TP53TG5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP53TG5 Gene

Publications for TP53TG5 Gene

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG5, which suppresses growth and shows cell cycle-dependent transition of expression. (PMID: 10719363) Isaka S. … Nakamura Y. (Genes Chromosomes Cancer 2000) 3 4 23 67
  2. Protein array based interactome analysis of amyloid-I^ indicates an inhibition of protein translation. (PMID: 21244100) Virok D.P. … FA1lAPp L. (J. Proteome Res. 2011) 3
  3. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for TP53TG5 Gene

Sources for TP53TG5 Gene