Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TP53TG3D Gene

Aliases for TP53TG3D Gene

  • TP53 Target 3D 2 3 5
  • TP53-Inducible Gene 3 Protein 3 4
  • TP53TG3 TP53TG3B TP53TG3C TP53TG3D TP53TG3E TP53TG3F 4
  • TP53-Target Gene 3 Protein 3
  • TP53TG3E 3
  • TP53TG3F 3
  • TP53TG3A 4
  • TP53TG3B 3
  • TP53TG3C 3
  • TP53TG3 3

External Ids for TP53TG3D Gene

Summaries for TP53TG3D Gene

GeneCards Summary for TP53TG3D Gene

TP53TG3D (TP53 Target 3D) is a Protein Coding gene. An important paralog of this gene is TP53TG3E.

UniProtKB/Swiss-Prot for TP53TG3D Gene

  • May play a significant role in p53/TP53-mediating signaling pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG3D Gene

Genomics for TP53TG3D Gene

Regulatory Elements for TP53TG3D Gene

Enhancers for TP53TG3D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TP53TG3D on UCSC Golden Path with GeneCards custom track

Promoters for TP53TG3D Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for TP53TG3D Gene

Chromosome:
16
Start:
32,252,719 bp from pter
End:
32,255,928 bp from pter
Size:
3,210 bases
Orientation:
Plus strand

Genomic View for TP53TG3D Gene

Genes around TP53TG3D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG3D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG3D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG3D Gene

Proteins for TP53TG3D Gene

  • Protein details for TP53TG3D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9ULZ0-T53G3_HUMAN
    Recommended name:
    TP53-target gene 3 protein
    Protein Accession:
    Q9ULZ0
    Secondary Accessions:
    • B2R5K6
    • Q4KN31
    • Q9ULY9

    Protein attributes for TP53TG3D Gene

    Size:
    132 amino acids
    Molecular mass:
    13627 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TP53TG3D Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TP53TG3D Gene

Post-translational modifications for TP53TG3D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TP53TG3D Gene

No data available for DME Specific Peptides for TP53TG3D Gene

Domains & Families for TP53TG3D Gene

Protein Domains for TP53TG3D Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TP53TG3D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG3D: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TP53TG3D Gene

Function for TP53TG3D Gene

Molecular function for TP53TG3D Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53.

Animal Model Products

CRISPR Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP53TG3D Gene

Localization for TP53TG3D Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG3D Gene

Gene Ontology (GO) - Cellular Components for TP53TG3D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TP53TG3D: view

No data available for Subcellular locations from COMPARTMENTS for TP53TG3D Gene

Pathways & Interactions for TP53TG3D Gene

SuperPathways for TP53TG3D Gene

No Data Available

Interacting Proteins for TP53TG3D Gene

Selected Interacting proteins: Q9ULZ0-T53G3_HUMAN for TP53TG3D Gene via IID

Symbol External ID(s) Details
ELAVL1
LRRK2

Gene Ontology (GO) - Biological Process for TP53TG3D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TP53TG3D Gene

Drugs & Compounds for TP53TG3D Gene

No Compound Related Data Available

Transcripts for TP53TG3D Gene

mRNA/cDNA for TP53TG3D Gene

(6) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TP53TG3D Gene

TP53 target 3D:
Representative Sequences:

CRISPR Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG3D Gene

No ASD Table

Relevant External Links for TP53TG3D Gene

GeneLoc Exon Structure for
TP53TG3D
ECgene alternative splicing isoforms for
TP53TG3D

Expression for TP53TG3D Gene

mRNA expression in normal human tissues for TP53TG3D Gene

mRNA differential expression in normal tissues according to GTEx for TP53TG3D Gene

This gene is overexpressed in Testis (x12.6).

Protein differential expression in normal tissues from HIPED for TP53TG3D Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TP53TG3D Gene



Protein tissue co-expression partners for TP53TG3D Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TP53TG3D Gene:

TP53TG3D

SOURCE GeneReport for Unigene cluster for TP53TG3D Gene:

Hs.513537

mRNA Expression by UniProt/SwissProt for TP53TG3D Gene:

Q9ULZ0-T53G3_HUMAN
Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle.
genes like me logo Genes that share expression patterns with TP53TG3D: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for TP53TG3D Gene

Orthologs for TP53TG3D Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TP53TG3D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC749815 34
  • 97.55 (n)
  • 98.17 (a)
-- 35
  • 98 (a)
OneToMany
Species where no ortholog for TP53TG3D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53TG3D Gene

ENSEMBL:
Gene Tree for TP53TG3D (if available)
TreeFam:
Gene Tree for TP53TG3D (if available)

Paralogs for TP53TG3D Gene

(3) SIMAP similar genes for TP53TG3D Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TP53TG3D: view

Variants for TP53TG3D Gene

Sequence variations from dbSNP and Humsavar for TP53TG3D Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1502 -- 32,255,239(-) ATTGT(A/G)ATTTA nc-transcript-variant, utr-variant-3-prime
rs10597 -- 32,255,145(+) AAGAC(A/C)AAAAC nc-transcript-variant, utr-variant-3-prime
rs15688 -- 32,255,058(+) AAGGT(A/G)AAGAA nc-transcript-variant, utr-variant-3-prime
rs696565 -- 32,255,856(-) tcaag(A/G)gatgc nc-transcript-variant, utr-variant-3-prime
rs698526 -- 32,251,416(-) gaaat(A/G)tattc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TP53TG3D Gene

Variant ID Type Subtype PubMed ID
dgv2835n100 CNV loss 25217958
dgv2836n100 CNV gain 25217958
dgv2837n100 CNV loss 25217958
dgv2838n100 CNV gain 25217958
dgv2839n100 CNV gain 25217958
dgv2840n100 CNV gain 25217958
dgv2841n100 CNV loss 25217958
dgv2842n100 CNV loss 25217958
dgv2843n100 CNV gain 25217958
dgv2844n100 CNV gain+loss 25217958
dgv2845n100 CNV gain 25217958
dgv2846n100 CNV gain+loss 25217958
dgv2847n100 CNV gain+loss 25217958
dgv2848n100 CNV gain+loss 25217958
dgv2849n100 CNV loss 25217958
dgv2850n100 CNV loss 25217958
dgv2851n100 CNV gain 25217958
dgv2852n100 CNV gain+loss 25217958
dgv2853n100 CNV loss 25217958
dgv2854n100 CNV gain 25217958
dgv2855n100 CNV loss 25217958
dgv2856n100 CNV gain 25217958
dgv2857n100 CNV loss 25217958
dgv2858n100 CNV gain+loss 25217958
dgv4991n54 CNV gain 21841781
dgv50e203 CNV gain+loss 21179565
dgv814e212 CNV gain 25503493
dgv815e212 CNV loss 25503493
dgv816e212 CNV loss 25503493
dgv817e212 CNV loss 25503493
esv2421440 OTHER complex 20811451
esv27116 CNV gain+loss 19812545
esv2714201 CNV deletion 23290073
esv29952 CNV gain 18421352
esv33069 CNV loss 17666407
esv3570542 CNV gain 25503493
esv3584708 CNV loss 24956385
esv3584926 CNV gain 24956385
esv3892833 CNV gain 25118596
esv3892842 CNV gain+loss 25118596
esv3892846 CNV gain 25118596
nsv1057653 CNV gain 25217958
nsv1060577 CNV loss 25217958
nsv1062513 CNV gain+loss 25217958
nsv1064477 CNV loss 25217958
nsv1139654 CNV duplication 24896259
nsv1146300 CNV duplication 26484159
nsv1160389 OTHER complex 26073780
nsv428325 CNV gain+loss 18775914
nsv433444 CNV gain 18776910
nsv436841 CNV insertion 17901297
nsv442720 CNV gain+loss 18776908
nsv520222 CNV loss 19592680
nsv527583 CNV gain 19592680
nsv571834 CNV loss 21841781
nsv571835 CNV loss 21841781
nsv571836 CNV loss 21841781
nsv571837 CNV loss 21841781
nsv7281 OTHER inversion 18451855
nsv821684 CNV gain 15273396
nsv833198 CNV gain+loss 17160897
nsv9439 CNV gain+loss 18304495
nsv977962 CNV duplication 23825009

Variation tolerance for TP53TG3D Gene

Gene Damage Index Score: 0.76; 16.00% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TP53TG3D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TP53TG3D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TP53TG3D Gene

Disorders for TP53TG3D Gene

Relevant External Links for TP53TG3D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TP53TG3D

No disorders were found for TP53TG3D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP53TG3D Gene

Publications for TP53TG3D Gene

  1. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 65
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for TP53TG3D Gene

Sources for TP53TG3D Gene

Content
Loading form....