TP53TG3C Gene
protein-coding GIFtS: 31
GCID: GC16P033205
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TP53 target 3C
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Aliases
for TP53TG3C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 8
| Aliases |
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| TP53 Target 3C1 2 | | TP53-Inducible Gene 3 Protein2 3 | | TP53TG32 | | TP53-Target Gene 3 Protein2 | | TP53TG3A3 |
| External Ids: | HGNC: 429621 | Entrez Gene: 6535502 | Ensembl: ENSG000002054577 | UniProtKB: Q9ULZ03 | | ORGUL members: | |
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| NONCODE:n375099 n375359 n377759 n377687 n375023 | see all 6 |
Export aliases for TP53TG3C gene to outside databases
|---|
Summaries
for TP53TG3C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: T53G3_HUMAN, Q9ULZ0Function: May play a significant role in p53/TP53-mediating signaling pathway
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Genomic Views
for TP53TG3C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NT_010393.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TP53TG3C
Other transcription factors
Search SABiosciences Chromatin IP Primers for TP53TG3C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TP53TG3C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2TP53TG3C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P033205: view genomic region
(about GC identifiers)
Start:
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33,204,156 bp from pter |
End:
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33,264,727 bp from pter |
Size:
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60,572 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr16+ 32,264,040-32,267,240 |
ORGUL member locations:
Legend (see complete legend)
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Proteins
for TP53TG3C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: T53G3_HUMAN, Q9ULZ0 (See
protein sequence)Recommended Name: TP53-target gene 3 protein Size: 132 amino acids; 13627 Da
Subcellular location: Cytoplasm. Nucleus
Secondary accessions: B2R5K6 Q4KN31 Q9ULY9Alternative splicing: 3 isoforms: Q9ULZ0-1 Q9ULZ0-2 Q9ULZ0-3 Explore the universe of human proteins at neXtProt for TP53TG3C: NX_Q9ULZ0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9ULZ0
TP53TG3C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001192188.1 NP_001192189.1
ENSEMBL proteins: ENSP00000455132 ENSP00000457790 ENSP00000353397 ENSP00000454442 ENSP00000381659 ENSP00000381658
Human Recombinant Protein Products for TP53TG3C:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
TP53TG3C for ontologies About GeneDecksing
TP53TG3C Antibody Products:
Assay Products for TP53TG3C: |
Protein
Domains /
Families
for TP53TG3C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9ULZ0 |
Function
for TP53TG3C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: T53G3_HUMAN, Q9ULZ0Function: May play a significant role in p53/TP53-mediating signaling pathwayInduction: By p53/TP53Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TP53TG3C |
|
Pathways & Interactions
for TP53TG3C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TP53TG3C
|
Drugs & Compounds
for TP53TG3C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TP53TG3C
Search CenterWatch for drugs/clinical trials and news about TP53TG3C / T53G3 
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Transcripts
for TP53TG3C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TP53TG3C gene (2 alternative transcripts): NM_001205259.1 NM_001205260.1 Unigene Cluster for TP53TG3C: TP53 target 3C Hs.624982 [show with all ESTs]Unigene Representative Sequence: NM_0012052609 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000561509(uc010cay.2 uc002edn.3) ENST00000569719(uc021thf.1)
ENST00000360260 ENST00000567137 ENST00000566959 ENST00000562714 ENST00000564949
ENST00000398667 ENST00000398666
Additional cDNA sequence: BC098165.1 5 DOTS entries: DT.100734283 DT.120715617 DT.95365457 DT.100809315 DT.120715573
GeneLoc Exon Structure
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Expression
for TP53TG3C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TP53TG3C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTCCATTAA
About this image
See TP53TG3C Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.624982
UniProtKB/Swiss-Prot: T53G3_HUMAN, Q9ULZ0Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle
SABiosciences Custom PCR Arrays for TP53TG3C
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TP53TG3C | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TP53TG3C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TP53TG3C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TP53TG3C |
Orthologs
for TP53TG3C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
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ENSEMBL Gene Tree for TP53TG3C (if available)
TreeFam Gene Tree for TP53TG3C (if available) |
Paralogs
for TP53TG3C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TP53TG3C gene
- TP53TG31 2 TP53TG3B1 2 TP53TG3D2
1 SIMAP similar gene for TP53TG3C using alignment to 1 protein entry: T53G3_HUMAN:TP53TG3
TP53TG3C for paralogs About GeneDecksing
|
Genomic Variants
for TP53TG3C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for TP53TG3C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TP53TG3C for disorders About GeneDecksing
1  disease for TP53TG3C: About MalaCardsparkinson's disease
Export disorders for TP53TG3C gene to outside databases
|
Publications
for TP53TG3C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TP53TG3C gene integrated from 9 sources:
(articles sorted by number of sources associating them with TP53TG3C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation and characterization of a novel TP53-inducible gene, TP53TG3. (PubMed id 10534768)1, 2 Ng C.C.... Nakamura Y. (1999)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M....Kim N.S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for TP53TG3C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing TP53TG3C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TP53TG3C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TP53TG3C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for TP53TG3C gene:
Search GeneIP for patents involving TP53TG3C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TP53TG3C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TP53TG3C | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TP53TG3C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TP53TG3C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TP53TG3C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TP53TG3C | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TP53TG3C |
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 | | | TP53TG3C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TP53TG3C |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TP53TG3C |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TP53TG3C |
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