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Aliases for TP53TG3C Gene

Aliases for TP53TG3C Gene

  • TP53 Target 3C 2 3 5
  • TP53-Inducible Gene 3 Protein 3 4
  • TP53TG3 TP53TG3B TP53TG3C TP53TG3D TP53TG3E TP53TG3F 4
  • TP53-Target Gene 3 Protein 3
  • TP53TG3E 3
  • TP53TG3F 3
  • TP53TG3A 4
  • TP53TG3 3

External Ids for TP53TG3C Gene

Summaries for TP53TG3C Gene

GeneCards Summary for TP53TG3C Gene

TP53TG3C (TP53 Target 3C) is a Protein Coding gene. An important paralog of this gene is LOC102723655.

UniProtKB/Swiss-Prot for TP53TG3C Gene

  • May play a significant role in p53/TP53-mediating signaling pathway.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG3C Gene

Genomics for TP53TG3C Gene

Regulatory Elements for TP53TG3C Gene


Promoters for TP53TG3C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085391 1142 1199

Genomic Location for TP53TG3C Gene

Chromosome:
16
Start:
33,193,659 bp from pter
End:
33,196,858 bp from pter
Size:
3,200 bases
Orientation:
Plus strand

Genomic View for TP53TG3C Gene

Genes around TP53TG3C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG3C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG3C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG3C Gene

Proteins for TP53TG3C Gene

  • Protein details for TP53TG3C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9ULZ0-T53G3_HUMAN
    Recommended name:
    TP53-target gene 3 protein
    Protein Accession:
    Q9ULZ0
    Secondary Accessions:
    • B2R5K6
    • Q4KN31
    • Q9ULY9

    Protein attributes for TP53TG3C Gene

    Size:
    132 amino acids
    Molecular mass:
    13627 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TP53TG3C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TP53TG3C Gene

Post-translational modifications for TP53TG3C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TP53TG3C Gene

Domains & Families for TP53TG3C Gene

Protein Domains for TP53TG3C Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG3C: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TP53TG3C Gene

Function for TP53TG3C Gene

Molecular function for TP53TG3C Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP53TG3C Gene

Localization for TP53TG3C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG3C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TP53TG3C gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for TP53TG3C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TP53TG3C: view

Pathways & Interactions for TP53TG3C Gene

SuperPathways for TP53TG3C Gene

No Data Available

Interacting Proteins for TP53TG3C Gene

Selected Interacting proteins: Q9ULZ0-T53G3_HUMAN for TP53TG3C Gene via IID

Symbol External ID(s) Details
ELAVL1
LRRK2

Gene Ontology (GO) - Biological Process for TP53TG3C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TP53TG3C Gene

Drugs & Compounds for TP53TG3C Gene

No Compound Related Data Available

Transcripts for TP53TG3C Gene

mRNA/cDNA for TP53TG3C Gene

(7) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TP53TG3C Gene

TP53 target 3C:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG3C Gene

No ASD Table

Relevant External Links for TP53TG3C Gene

GeneLoc Exon Structure for
TP53TG3C
ECgene alternative splicing isoforms for
TP53TG3C

Expression for TP53TG3C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TP53TG3C Gene

mRNA differential expression in normal tissues according to GTEx for TP53TG3C Gene

This gene is overexpressed in Testis (x24.6).

Protein differential expression in normal tissues from HIPED for TP53TG3C Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TP53TG3C Gene



Protein tissue co-expression partners for TP53TG3C Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TP53TG3C Gene:

TP53TG3C

SOURCE GeneReport for Unigene cluster for TP53TG3C Gene:

Hs.624982

mRNA Expression by UniProt/SwissProt for TP53TG3C Gene:

Q9ULZ0-T53G3_HUMAN
Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle.
genes like me logo Genes that share expression patterns with TP53TG3C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TP53TG3C Gene

Orthologs for TP53TG3C Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TP53TG3C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 98 (a)
OneToMany
LOC749815 34
  • 97.55 (n)
Species where no ortholog for TP53TG3C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53TG3C Gene

ENSEMBL:
Gene Tree for TP53TG3C (if available)
TreeFam:
Gene Tree for TP53TG3C (if available)

Paralogs for TP53TG3C Gene

(2) SIMAP similar genes for TP53TG3C Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TP53TG3C: view

Variants for TP53TG3C Gene

Sequence variations from dbSNP and Humsavar for TP53TG3C Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1004296501 -- 33,190,218(+) CTTCT(A/G)TTAAT upstream-variant-2KB
rs1019658028 -- 33,190,221(+) CTATT(A/G)ATAAA upstream-variant-2KB
rs1027142705 -- 33,189,922(+) TACTA(A/C)AAAAA upstream-variant-2KB
rs1028219820 -- 33,190,641(+) GTCAC(A/G)GTTTC upstream-variant-2KB
rs113609538 -- 33,190,342(+) AAGAA(A/G)ACACC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TP53TG3C Gene

Variant ID Type Subtype PubMed ID
dgv117n111 CNV deletion 26073780
dgv119n111 CNV duplication 26073780
dgv120n111 CNV duplication 26073780
dgv121n111 CNV duplication 26073780
dgv1557e59 CNV duplication 20981092
dgv2837n100 CNV loss 25217958
dgv2838n100 CNV gain 25217958
dgv2839n100 CNV gain 25217958
dgv2840n100 CNV gain 25217958
dgv2841n100 CNV loss 25217958
dgv2842n100 CNV loss 25217958
dgv2844n100 CNV gain+loss 25217958
dgv2847n100 CNV gain+loss 25217958
dgv2851n100 CNV gain 25217958
dgv2852n100 CNV gain+loss 25217958
dgv2854n100 CNV gain 25217958
dgv2858n100 CNV gain+loss 25217958
dgv2861n100 CNV loss 25217958
dgv2862n100 CNV loss 25217958
dgv2866n100 CNV gain+loss 25217958
dgv2867n100 CNV gain 25217958
dgv2868n100 CNV loss 25217958
dgv2869n100 CNV gain 25217958
dgv2870n100 CNV gain+loss 25217958
dgv2871n100 CNV gain 25217958
dgv2872n100 CNV gain+loss 25217958
dgv2873n100 CNV gain 25217958
dgv2874n100 CNV loss 25217958
dgv2875n100 CNV loss 25217958
dgv2876n100 CNV loss 25217958
dgv2877n100 CNV loss 25217958
dgv2882n100 CNV gain 25217958
dgv2884n100 CNV loss 25217958
dgv2891n100 CNV loss 25217958
dgv2892n100 CNV loss 25217958
dgv2893n100 CNV loss 25217958
dgv2896n100 CNV loss 25217958
dgv2897n100 CNV gain+loss 25217958
dgv2898n100 CNV gain 25217958
dgv2899n100 CNV loss 25217958
dgv2900n100 CNV gain 25217958
dgv2901n100 CNV gain+loss 25217958
dgv2902n100 CNV gain 25217958
dgv2903n100 CNV gain+loss 25217958
dgv2904n100 CNV loss 25217958
dgv2905n100 CNV gain 25217958
dgv336e201 CNV deletion 23290073
dgv491e199 CNV deletion 23128226
dgv4996n54 CNV gain 21841781
dgv5008n54 CNV loss 21841781
dgv5009n54 CNV loss 21841781
dgv5027n54 CNV loss 21841781
dgv5048n54 CNV loss 21841781
dgv5049n54 CNV gain 21841781
dgv50e203 CNV gain+loss 21179565
dgv814e212 CNV gain 25503493
dgv816e212 CNV loss 25503493
dgv817e212 CNV loss 25503493
dgv819e212 CNV loss 25503493
dgv820e212 CNV gain 25503493
dgv821e212 CNV gain 25503493
dgv822e212 CNV gain 25503493
dgv823e212 CNV loss 25503493
esv1011117 CNV gain 20482838
esv2421440 OTHER complex 20811451
esv24815 CNV gain+loss 19812545
esv2629091 CNV gain 19546169
esv27116 CNV gain+loss 19812545
esv2714201 CNV deletion 23290073
esv2714208 CNV deletion 23290073
esv2714223 CNV deletion 23290073
esv29952 CNV gain 18421352
esv33069 CNV loss 17666407
esv3365693 CNV duplication 20981092
esv3570542 CNV gain 25503493
esv3584927 CNV gain 24956385
esv3892840 CNV gain 25118596
esv3892841 CNV gain+loss 25118596
esv992951 CNV gain 20482838
nsv1055691 CNV loss 25217958
nsv1056035 CNV gain 25217958
nsv1057046 CNV gain+loss 25217958
nsv1057297 CNV gain 25217958
nsv1061657 CNV gain 25217958
nsv1062147 CNV gain 25217958
nsv1062513 CNV gain+loss 25217958
nsv1063376 CNV loss 25217958
nsv1064239 CNV loss 25217958
nsv1070762 CNV deletion 25765185
nsv1124737 CNV duplication 24896259
nsv1139655 CNV duplication 24896259
nsv1146300 CNV duplication 26484159
nsv1146576 CNV duplication 26484159
nsv1160392 CNV deletion 26073780
nsv1160394 OTHER complex 26073780
nsv1160395 CNV duplication 26073780
nsv1160406 CNV duplication 26073780
nsv1160412 OTHER complex 26073780
nsv1160413 CNV duplication 26073780
nsv1790 CNV deletion 18451855
nsv428325 CNV gain+loss 18775914
nsv433444 CNV gain 18776910
nsv436841 CNV insertion 17901297
nsv469892 CNV gain+loss 16826518
nsv471390 CNV gain 19718026
nsv471500 CNV gain 19718026
nsv471692 CNV gain+loss 15918152
nsv482194 CNV gain 20164927
nsv510684 CNV deletion 20534489
nsv511048 OTHER complex 20534489
nsv520222 CNV loss 19592680
nsv527583 CNV gain 19592680
nsv571834 CNV loss 21841781
nsv571835 CNV loss 21841781
nsv571869 CNV gain+loss 21841781
nsv572013 CNV gain 21841781
nsv572198 CNV loss 21841781
nsv572204 CNV loss 21841781
nsv572208 CNV loss 21841781
nsv572209 CNV loss 21841781
nsv7281 OTHER inversion 18451855
nsv7282 OTHER inversion 18451855
nsv821684 CNV gain 15273396
nsv833201 CNV gain+loss 17160897
nsv833202 CNV gain 17160897
nsv9439 CNV gain+loss 18304495
nsv952324 CNV duplication 24416366
nsv977969 CNV duplication 23825009
nsv978136 CNV duplication 23825009
nsv978137 CNV duplication 23825009

Relevant External Links for TP53TG3C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TP53TG3C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TP53TG3C Gene

Disorders for TP53TG3C Gene

Relevant External Links for TP53TG3C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TP53TG3C

No disorders were found for TP53TG3C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP53TG3C Gene

Publications for TP53TG3C Gene

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. (PMID: 10534768) Ng C.C. … Nakamura Y. (Genes Chromosomes Cancer 1999) 3 4 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Identification of genes related to Parkinson's disease using expressed sequence tags. (PMID: 17213182) Kim J.M. … Kim N.S. (DNA Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for TP53TG3C Gene

Sources for TP53TG3C Gene

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