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Aliases for TP53TG3 Gene

Aliases for TP53TG3 Gene

  • TP53 Target 3 2 3 5
  • TP53-Inducible Gene 3 Protein 3 4
  • P53 Target Gene 3 2 3
  • TP53TG3A 3 4
  • TP53TG3 TP53TG3B TP53TG3C TP53TG3D TP53TG3E TP53TG3F 4
  • TP53-Target Gene 3 Protein 3
  • TP53TG3E 3
  • TP53TG3F 3
  • P53TG3 3

External Ids for TP53TG3 Gene

Previous GeneCards Identifiers for TP53TG3 Gene

  • GC16P032118
  • GC16P033256
  • GC16M032682
  • GC16M032721
  • GC16P032172
  • GC16M032590

Summaries for TP53TG3 Gene

GeneCards Summary for TP53TG3 Gene

TP53TG3 (TP53 Target 3) is a Protein Coding gene. An important paralog of this gene is TP53TG3E.

UniProtKB/Swiss-Prot for TP53TG3 Gene

  • May play a significant role in p53/TP53-mediating signaling pathway.

Additional gene information for TP53TG3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG3 Gene

Genomics for TP53TG3 Gene

Regulatory Elements for TP53TG3 Gene

Promoters for TP53TG3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085380 1032 1001

Genomic Locations for TP53TG3 Gene

Genomic Locations for TP53TG3 Gene
3,205 bases
Minus strand

Genomic View for TP53TG3 Gene

Genes around TP53TG3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG3 Gene

Proteins for TP53TG3 Gene

  • Protein details for TP53TG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    TP53-target gene 3 protein
    Protein Accession:
    Secondary Accessions:
    • B2R5K6
    • Q4KN31
    • Q9ULY9

    Protein attributes for TP53TG3 Gene

    132 amino acids
    Molecular mass:
    13627 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TP53TG3 Gene


neXtProt entry for TP53TG3 Gene

Post-translational modifications for TP53TG3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TP53TG3 Gene

No data available for DME Specific Peptides for TP53TG3 Gene

Domains & Families for TP53TG3 Gene

Gene Families for TP53TG3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TP53TG3 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG3: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TP53TG3 Gene

Function for TP53TG3 Gene

Molecular function for TP53TG3 Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53.

Phenotypes for TP53TG3 Gene

GenomeRNAi human phenotypes for TP53TG3:
genes like me logo Genes that share phenotypes with TP53TG3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP53TG3 Gene

Localization for TP53TG3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG3 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TP53TG3 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for TP53TG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TP53TG3: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TP53TG3 Gene

Pathways & Interactions for TP53TG3 Gene

SuperPathways for TP53TG3 Gene

No Data Available

Interacting Proteins for TP53TG3 Gene

Selected Interacting proteins: Q9ULZ0-T53G3_HUMAN for TP53TG3 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TP53TG3 Gene


No data available for Pathways by source and SIGNOR curated interactions for TP53TG3 Gene

Drugs & Compounds for TP53TG3 Gene

No Compound Related Data Available

Transcripts for TP53TG3 Gene

mRNA/cDNA for TP53TG3 Gene

(7) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG3 Gene

No ASD Table

Relevant External Links for TP53TG3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TP53TG3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TP53TG3 Gene

mRNA differential expression in normal tissues according to GTEx for TP53TG3 Gene

This gene is overexpressed in Testis (x44.9) and Brain - Frontal Cortex (BA9) (x4.3).

Protein differential expression in normal tissues from HIPED for TP53TG3 Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TP53TG3 Gene

Protein tissue co-expression partners for TP53TG3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TP53TG3 Gene:


mRNA Expression by UniProt/SwissProt for TP53TG3 Gene:

Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle.
genes like me logo Genes that share expression patterns with TP53TG3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TP53TG3 Gene

Orthologs for TP53TG3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TP53TG3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 98 (a)
LOC749815 33
  • 97.55 (n)
Species where no ortholog for TP53TG3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53TG3 Gene

Gene Tree for TP53TG3 (if available)
Gene Tree for TP53TG3 (if available)

Paralogs for TP53TG3 Gene

(3) SIMAP similar genes for TP53TG3 Gene using alignment to 2 proteins: Pseudogenes for TP53TG3 Gene

genes like me logo Genes that share paralogs with TP53TG3: view

Variants for TP53TG3 Gene

Sequence variations from dbSNP and Humsavar for TP53TG3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1012111496 -- 32,677,000(+) TGGAA(C/G)TGAAT upstream-variant-2KB, utr-variant-5-prime
rs1021593997 -- 32,677,044(+) ACCTG(C/T)CAGGT upstream-variant-2KB, utr-variant-5-prime
rs1029191503 -- 32,676,970(+) CCCTC(A/T)GGAAC upstream-variant-2KB, utr-variant-5-prime
rs1035585912 -- 32,677,287(+) TTAAT(C/G)TCCAT upstream-variant-2KB, utr-variant-5-prime
rs1036631996 -- 32,676,945(+) TAAAA(C/G)AAACA upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for TP53TG3 Gene

Variant ID Type Subtype PubMed ID
nsv978137 CNV duplication 23825009
nsv978136 CNV duplication 23825009
nsv977969 CNV duplication 23825009
nsv952324 CNV duplication 24416366
nsv9439 CNV gain+loss 18304495
nsv833202 CNV gain 17160897
nsv833201 CNV gain+loss 17160897
nsv821684 CNV gain 15273396
nsv7282 OTHER inversion 18451855
nsv7281 OTHER inversion 18451855
nsv572209 CNV loss 21841781
nsv572208 CNV loss 21841781
nsv572204 CNV loss 21841781
nsv572198 CNV loss 21841781
nsv572013 CNV gain 21841781
nsv571869 CNV gain+loss 21841781
nsv571835 CNV loss 21841781
nsv571834 CNV loss 21841781
nsv527583 CNV gain 19592680
nsv520222 CNV loss 19592680
nsv511048 OTHER complex 20534489
nsv510684 CNV deletion 20534489
nsv482194 CNV gain 20164927
nsv471692 CNV gain+loss 15918152
nsv471500 CNV gain 19718026
nsv471390 CNV gain 19718026
nsv469892 CNV gain+loss 16826518
nsv436841 CNV insertion 17901297
nsv433444 CNV gain 18776910
nsv428325 CNV gain+loss 18775914
nsv1790 CNV deletion 18451855
nsv1160413 CNV duplication 26073780
nsv1160412 OTHER complex 26073780
nsv1160406 CNV duplication 26073780
nsv1160395 CNV duplication 26073780
nsv1160394 OTHER complex 26073780
nsv1160392 CNV deletion 26073780
nsv1146576 CNV duplication 26484159
nsv1146300 CNV duplication 26484159
nsv1139655 CNV duplication 24896259
nsv1124737 CNV duplication 24896259
nsv1070762 CNV deletion 25765185
nsv1064239 CNV loss 25217958
nsv1063376 CNV loss 25217958
nsv1062513 CNV gain+loss 25217958
nsv1062147 CNV gain 25217958
nsv1061657 CNV gain 25217958
nsv1057297 CNV gain 25217958
nsv1057046 CNV gain+loss 25217958
nsv1056035 CNV gain 25217958
nsv1055691 CNV loss 25217958
esv992951 CNV gain 20482838
esv3892841 CNV gain+loss 25118596
esv3892840 CNV gain 25118596
esv3584927 CNV gain 24956385
esv3570542 CNV gain 25503493
esv3365693 CNV duplication 20981092
esv33069 CNV loss 17666407
esv29952 CNV gain 18421352
esv2714223 CNV deletion 23290073
esv2714208 CNV deletion 23290073
esv2714201 CNV deletion 23290073
esv27116 CNV gain+loss 19812545
esv2629091 CNV gain 19546169
esv24815 CNV gain+loss 19812545
esv2421440 OTHER complex 20811451
esv1011117 CNV gain 20482838
dgv823e212 CNV loss 25503493
dgv822e212 CNV gain 25503493
dgv821e212 CNV gain 25503493
dgv820e212 CNV gain 25503493
dgv819e212 CNV loss 25503493
dgv817e212 CNV loss 25503493
dgv816e212 CNV loss 25503493
dgv814e212 CNV gain 25503493
dgv50e203 CNV gain+loss 21179565
dgv5049n54 CNV gain 21841781
dgv5048n54 CNV loss 21841781
dgv5027n54 CNV loss 21841781
dgv5009n54 CNV loss 21841781
dgv5008n54 CNV loss 21841781
dgv4996n54 CNV gain 21841781
dgv491e199 CNV deletion 23128226
dgv336e201 CNV deletion 23290073
dgv2905n100 CNV gain 25217958
dgv2904n100 CNV loss 25217958
dgv2903n100 CNV gain+loss 25217958
dgv2902n100 CNV gain 25217958
dgv2901n100 CNV gain+loss 25217958
dgv2900n100 CNV gain 25217958
dgv2899n100 CNV loss 25217958
dgv2898n100 CNV gain 25217958
dgv2897n100 CNV gain+loss 25217958
dgv2896n100 CNV loss 25217958
dgv2893n100 CNV loss 25217958
dgv2892n100 CNV loss 25217958
dgv2891n100 CNV loss 25217958
dgv2884n100 CNV loss 25217958
dgv2882n100 CNV gain 25217958
dgv2877n100 CNV loss 25217958
dgv2876n100 CNV loss 25217958
dgv2875n100 CNV loss 25217958
dgv2874n100 CNV loss 25217958
dgv2873n100 CNV gain 25217958
dgv2872n100 CNV gain+loss 25217958
dgv2871n100 CNV gain 25217958
dgv2870n100 CNV gain+loss 25217958
dgv2869n100 CNV gain 25217958
dgv2868n100 CNV loss 25217958
dgv2867n100 CNV gain 25217958
dgv2866n100 CNV gain+loss 25217958
dgv2862n100 CNV loss 25217958
dgv2861n100 CNV loss 25217958
dgv2858n100 CNV gain+loss 25217958
dgv2854n100 CNV gain 25217958
dgv2852n100 CNV gain+loss 25217958
dgv2851n100 CNV gain 25217958
dgv2847n100 CNV gain+loss 25217958
dgv2844n100 CNV gain+loss 25217958
dgv2842n100 CNV loss 25217958
dgv2841n100 CNV loss 25217958
dgv2840n100 CNV gain 25217958
dgv2839n100 CNV gain 25217958
dgv2838n100 CNV gain 25217958
dgv2837n100 CNV loss 25217958
dgv1557e59 CNV duplication 20981092
dgv121n111 CNV duplication 26073780
dgv120n111 CNV duplication 26073780
dgv119n111 CNV duplication 26073780
dgv117n111 CNV deletion 26073780

Relevant External Links for TP53TG3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TP53TG3 Gene

Disorders for TP53TG3 Gene

Relevant External Links for TP53TG3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TP53TG3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP53TG3 Gene

Publications for TP53TG3 Gene

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. (PMID: 10534768) Ng CC … Nakamura Y (Genes, chromosomes & cancer 1999) 2 3 4 22 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K … Gorospe M (The EMBO journal 2009) 3 60
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for TP53TG3 Gene

Sources for TP53TG3 Gene

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