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Aliases for TP53TG3 Gene

Aliases for TP53TG3 Gene

  • TP53 Target 3 2 3
  • TP53-Inducible Gene 3 Protein 3 4
  • P53 Target Gene 3 2 3
  • TP53TG3A 3 4
  • TP53TG3 TP53TG3B TP53TG3C TP53TG3D 4
  • TP53-Target Gene 3 Protein 3
  • P53TG3 3

External Ids for TP53TG3 Gene

Previous GeneCards Identifiers for TP53TG3 Gene

  • GC16P032118
  • GC16P033256
  • GC16M032682
  • GC16M032721
  • GC16P032172
  • GC16M032590

Summaries for TP53TG3 Gene

GeneCards Summary for TP53TG3 Gene

TP53TG3 (TP53 Target 3) is a Protein Coding gene. An important paralog of this gene is TP53TG3C.

UniProtKB/Swiss-Prot for TP53TG3 Gene

  • May play a significant role in p53/TP53-mediating signaling pathway.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG3 Gene

Genomics for TP53TG3 Gene

Regulatory Elements for TP53TG3 Gene

Genomic Location for TP53TG3 Gene

Start:
32,673,528 bp from pter
End:
32,676,920 bp from pter
Size:
3,393 bases
Orientation:
Minus strand

Genomic View for TP53TG3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TP53TG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG3 Gene

Proteins for TP53TG3 Gene

  • Protein details for TP53TG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9ULZ0-T53G3_HUMAN
    Recommended name:
    TP53-target gene 3 protein
    Protein Accession:
    Q9ULZ0
    Secondary Accessions:
    • B2R5K6
    • Q4KN31
    • Q9ULY9

    Protein attributes for TP53TG3 Gene

    Size:
    132 amino acids
    Molecular mass:
    13627 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TP53TG3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TP53TG3 Gene

Proteomics data for TP53TG3 Gene at MOPED

Post-translational modifications for TP53TG3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TP53TG3 Gene

No data available for DME Specific Peptides for TP53TG3 Gene

Domains for TP53TG3 Gene

Protein Domains for TP53TG3 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TP53TG3 Gene

Function for TP53TG3 Gene

Molecular function for TP53TG3 Gene

UniProtKB/Swiss-Prot Function:
May play a significant role in p53/TP53-mediating signaling pathway.
UniProtKB/Swiss-Prot Induction:
By p53/TP53.

Phenotypes for TP53TG3 Gene

GenomeRNAi human phenotypes for TP53TG3:
genes like me logo Genes that share phenotypes with TP53TG3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TP53TG3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TP53TG3 Gene

Localization for TP53TG3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53TG3 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TP53TG3 Gene COMPARTMENTS Subcellular localization image for TP53TG3 gene
Compartment Confidence
nucleus 5
extracellular 2
mitochondrion 2
cytosol 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TP53TG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TP53TG3: view

Pathways for TP53TG3 Gene

SuperPathways for TP53TG3 Gene

No Data Available

Interacting Proteins for TP53TG3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000381672%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000381672 for TP53TG3 Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for TP53TG3 Gene

None

No data available for Pathways by source for TP53TG3 Gene

Transcripts for TP53TG3 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TP53TG3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG3 Gene

No ASD Table

Relevant External Links for TP53TG3 Gene

GeneLoc Exon Structure for
TP53TG3
ECgene alternative splicing isoforms for
TP53TG3

Expression for TP53TG3 Gene

mRNA expression in normal human tissues for TP53TG3 Gene

mRNA differential expression in normal tissues according to GTEx for TP53TG3 Gene

This gene is overexpressed in Testis (44.9) and Brain - Frontal Cortex (BA9) (4.3).

Protein differential expression in normal tissues for TP53TG3 Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TP53TG3 Gene

mRNA Expression by UniProt/SwissProt for TP53TG3 Gene

Q9ULZ0-T53G3_HUMAN
Tissue specificity: Strongly expressed in testis. Weakly expressed in heart, placenta and skeletal muscle.
genes like me logo Genes that share expressions with TP53TG3: view

Expression partners for TP53TG3 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for TP53TG3 Gene

Orthologs for TP53TG3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TP53TG3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC749815 35
  • 97.55 (n)
  • 98.17 (a)
-- 36
  • 98 (a)
OneToMany
Species with no ortholog for TP53TG3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53TG3 Gene

ENSEMBL:
Gene Tree for TP53TG3 (if available)
TreeFam:
Gene Tree for TP53TG3 (if available)

Paralogs for TP53TG3 Gene

Paralogs for TP53TG3 Gene

Selected SIMAP similar genes for TP53TG3 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for TP53TG3 Gene

genes like me logo Genes that share paralogs with TP53TG3: view

Variants for TP53TG3 Gene

Sequence variations from dbSNP and Humsavar for TP53TG3 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs75233432 -- 32,678,592(+) GTTTT(A/G)GGAGG upstream-variant-2KB
rs200510818 -- 32,675,774(+) CACCG(A/G)CCCTT intron-variant, reference, synonymous-codon, nc-transcript-variant
rs532634194 -- 32,678,875(+) TAATA(A/G)GCAAT upstream-variant-2KB
rs547139856 -- 32,673,935(+) GGATG(A/T)CTGAG utr-variant-3-prime, nc-transcript-variant
rs565261361 -- 32,676,969(+) TCCCT(C/T)AGGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TP53TG3 Gene

Variant ID Type Subtype PubMed ID
dgv848e1 CNV Complex 17122850
dgv853e1 CNV Complex 17122850
nsv428325 CNV Gain+Loss 18775914
nsv9439 CNV Gain+Loss 18304495
dgv2677n71 CNV Gain 21882294
nsv433444 CNV Gain 18776910
essv11015 CNV CNV 17122850
esv29952 CNV Gain 18421352
esv33069 CNV Loss 17666407
nsv436841 CNV Insertion 17901297
esv2714201 CNV Deletion 23290073
dgv856e1 CNV Complex 17122850
dgv857e1 CNV Complex 17122850
dgv2682n71 CNV Gain 21882294
nsv520222 CNV Loss 19592680
nsv527583 CNV Gain 19592680
nsv7281 OTHER Inversion 18451855
esv27116 CNV Gain+Loss 19812545
nsv821684 CNV Gain 15273396
dgv861e1 CNV Complex 17122850
dgv862e1 CNV Complex 17122850
esv2421440 OTHER Complex 20811451
dgv491e199 CNV Deletion 23128226
dgv863e1 CNV Complex 17122850
dgv864e1 CNV Complex 17122850
nsv905829 CNV Gain 21882294
dgv373e201 CNV Deletion 23290073
dgv865e1 CNV Complex 17122850
dgv866e1 CNV Complex 17122850
dgv2698n71 CNV Loss 21882294
dgv2707n71 CNV Gain 21882294
dgv2708n71 CNV Loss 21882294
nsv905900 CNV Gain 21882294
esv2714208 CNV Deletion 23290073
dgv2713n71 CNV Gain 21882294
dgv2719n71 CNV Loss 21882294
dgv867e1 CNV Complex 17122850
dgv868e1 CNV Complex 17122850
esv2629091 CNV Gain 19546169
nsv833201 CNV Gain+Loss 17160897
nsv469892 CNV Complex 16826518
nsv471692 CNV Gain+Loss 15918152
dgv2801n71 CNV Gain 21882294
nsv906423 CNV Loss 21882294
nsv471500 CNV Duplication 19718026
esv1011117 CNV Gain 20482838
nsv483054 CNV Complex 15286789
dgv869e1 CNV Complex 17122850
dgv870e1 CNV Complex 17122850
dgv872e1 CNV Complex 17122850
nsv7282 OTHER Inversion 18451855
dgv2822n71 CNV Gain 21882294
dgv873e1 CNV Complex 17122850
dgv874e1 CNV Complex 17122850
dgv875e1 CNV Complex 17122850
dgv2823n71 CNV Loss 21882294
nsv833202 CNV Gain 17160897
esv24815 CNV Gain+Loss 19812545
essv5744 CNV CNV 17122850
dgv876e1 CNV Complex 17122850
dgv2824n71 CNV Gain 21882294
dgv2825n71 CNV Loss 21882294
nsv906527 CNV Gain 21882294
esv992951 CNV Gain 20482838
dgv877e1 CNV Complex 17122850
nsv471390 CNV Duplication 19718026
nsv482194 CNV Gain 20164927
nsv510684 CNV Loss 20534489
nsv511048 CNV Complex 20534489
esv2714223 CNV Deletion 23290073
nsv1790 CNV Loss 18451855
dgv878e1 CNV Complex 17122850
dgv879e1 CNV Complex 17122850

Relevant External Links for TP53TG3 Gene

HapMap Linkage Disequilibrium report
TP53TG3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TP53TG3 Gene

Disorders for TP53TG3 Gene

No disorders were found for TP53TG3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TP53TG3 Gene

Publications for TP53TG3 Gene

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. (PMID: 10534768) Ng C.C. … Nakamura Y. (Genes Chromosomes Cancer 1999) 2 3 4 23
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for TP53TG3 Gene

Sources for TP53TG3 Gene

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