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Aliases for TP53TG1 Gene

Subcategory (RNA class) for TP53TG1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for TP53TG1 Gene

  • TP53 Target 1 (Non-Protein Coding) 2 3 5
  • Long Intergenic Non-Protein Coding RNA 96 2 3
  • TP53 Activated Protein 1 2 3
  • TP53 Target Gene 1 2 3
  • TP53AP1 3 4
  • P53TG1 3 4
  • Tumor Protein P53-Activated Protein 1 4
  • TP53-Inducible Gene 1 Protein 4
  • H_RG012D21.9 3
  • NCRNA00096 3
  • LINC00096 3
  • P53TG1-D 3

External Ids for TP53TG1 Gene

Previous HGNC Symbols for TP53TG1 Gene

  • TP53AP1

Previous GeneCards Identifiers for TP53TG1 Gene

  • GC07M085489
  • GC07U902535
  • GC07M086792
  • GC07M086954
  • GC07M081565

Summaries for TP53TG1 Gene

GeneCards Summary for TP53TG1 Gene

TP53TG1 (TP53 Target 1 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53TG1 Gene

Genomics for TP53TG1 Gene

Regulatory Elements for TP53TG1 Gene

Enhancers for TP53TG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F087338 0.7 ENCODE 18.2 +5.9 5860 1.4 SOX13 PKNOX1 TFAP4 CEBPG ZIC2 RAD21 YY1 FOSL1 HNF4G NR2F6 TP53TG1 ENSG00000273623 PIR31944
GH07F087318 1.4 FANTOM5 Ensembl ENCODE 17.5 +26.3 26263 1.0 CTCF SAP130 SP5 FOXA3 DMAP1 ZNF48 ZNF644 RAD21 E2F1 GATA3 CROT TP53TG1 LOC101927420 PIR31944 ENSG00000273623
GH07F087343 0.5 ENCODE 15.3 +0.1 140 4.4 HDGF PKNOX1 ATF1 ARID4B SIN3A FEZF1 ZNF48 ZNF2 YY1 FOS TP53TG1 ENSG00000276185 GC07M087345
GH07F087337 0.2 ENCODE 15 +8.0 7959 0.6 TP53TG1 ENSG00000273623 PIR31944
GH07F087331 1 ENCODE 13.3 +13.6 13591 2.6 ATF1 ARNT ELK1 GATA2 KLF13 NCOA1 CREB3 MBD2 MEF2D SMARCA4 TP53TG1 CROT LOC101927420 ENSG00000273623 PIR31944
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TP53TG1 on UCSC Golden Path with GeneCards custom track

Promoters for TP53TG1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001561581 415 3001 HDGF PKNOX1 ATF1 MLX ARID4B SIN3A FEZF1 ZNF48 ZNF2 YY1
ENSR00001893791 -1385 200

Genomic Location for TP53TG1 Gene

Chromosome:
7
Start:
87,325,225 bp from pter
End:
87,345,515 bp from pter
Size:
20,291 bases
Orientation:
Minus strand

Genomic View for TP53TG1 Gene

Genes around TP53TG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TP53TG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TP53TG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53TG1 Gene

Proteins for TP53TG1 Gene

  • Protein details for TP53TG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2A0-T53G1_HUMAN
    Recommended name:
    TP53-target gene 1 protein
    Protein Accession:
    Q9Y2A0
    Secondary Accessions:
    • D6W5P2
    • Q52MB0
    • Q9Y2A1
    • Q9Y2A2
    • Q9Y2A3

    Protein attributes for TP53TG1 Gene

    Size:
    90 amino acids
    Molecular mass:
    10275 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TP53TG1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TP53TG1 Gene

Post-translational modifications for TP53TG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TP53TG1 Gene

Domains & Families for TP53TG1 Gene

Gene Families for TP53TG1 Gene

Protein Domains for TP53TG1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TP53TG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53TG1: view

No data available for UniProtKB/Swiss-Prot for TP53TG1 Gene

Function for TP53TG1 Gene

Molecular function for TP53TG1 Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated by UV irradiation and exposure to bleomycin or cisplatin in a p53/TP53-dependent manner.

Gene Ontology (GO) - Molecular Function for TP53TG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TP53TG1: view

Phenotypes for TP53TG1 Gene

GenomeRNAi human phenotypes for TP53TG1:
genes like me logo Genes that share phenotypes with TP53TG1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TP53TG1 Gene

Localization for TP53TG1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TP53TG1 Gene

Pathways & Interactions for TP53TG1 Gene

SuperPathways for TP53TG1 Gene

No Data Available

Interacting Proteins for TP53TG1 Gene

Selected Interacting proteins: Q9Y2A0-T53G1_HUMAN for TP53TG1 Gene via IID

Gene Ontology (GO) - Biological Process for TP53TG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006950 response to stress TAS 9713990
GO:0006974 cellular response to DNA damage stimulus NAS 9713990
genes like me logo Genes that share ontologies with TP53TG1: view

No data available for Pathways by source and SIGNOR curated interactions for TP53TG1 Gene

Transcripts for TP53TG1 Gene

Unigene Clusters for TP53TG1 Gene

TP53 target 1 (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TP53TG1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2
SP1: -
SP2:
SP3: - -
SP4: -

Relevant External Links for TP53TG1 Gene

GeneLoc Exon Structure for
TP53TG1
ECgene alternative splicing isoforms for
TP53TG1

Expression for TP53TG1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TP53TG1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TP53TG1 Gene:

TP53TG1

SOURCE GeneReport for Unigene cluster for TP53TG1 Gene:

Hs.274329

mRNA Expression by UniProt/SwissProt for TP53TG1 Gene:

Q9Y2A0-T53G1_HUMAN
Tissue specificity: Isoform 1, isoform 2, isoform 3 and isoform 4 are ubiquitously expressed.
genes like me logo Genes that share expression patterns with TP53TG1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TP53TG1 Gene

Orthologs for TP53TG1 Gene

Evolution for TP53TG1 Gene

ENSEMBL:
Gene Tree for TP53TG1 (if available)
TreeFam:
Gene Tree for TP53TG1 (if available)

No data available for Orthologs for TP53TG1 Gene

Paralogs for TP53TG1 Gene

No data available for Paralogs for TP53TG1 Gene

Variants for TP53TG1 Gene

Sequence variations from dbSNP and Humsavar for TP53TG1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10248111 -- 87,328,331(+) gttac(C/T)tatct intron-variant
rs10447793 -- 87,338,671(+) AATAA(C/T)TCCTG intron-variant
rs10499902 -- 87,335,653(+) gataa(A/G)taagt intron-variant
rs10560512 -- 87,346,199(+) TTTGC(-/GT)GTGTT intron-variant, upstream-variant-2KB
rs1089470 -- 87,324,906(+) caaga(C/T)gattt downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TP53TG1 Gene

Variant ID Type Subtype PubMed ID
esv3304880 CNV mobile element insertion 20981092
esv3307982 CNV mobile element insertion 20981092
esv3391965 CNV insertion 20981092
esv3423823 CNV insertion 20981092
esv3449592 CNV insertion 20981092
nsv1022111 CNV loss 25217958
nsv428177 CNV loss 18775914
nsv464622 CNV gain 19166990
nsv607725 CNV gain 21841781
nsv970548 CNV duplication 23825009

Relevant External Links for TP53TG1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TP53TG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TP53TG1 Gene

Disorders for TP53TG1 Gene

Relevant External Links for TP53TG1

Genetic Association Database (GAD)
TP53TG1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TP53TG1

No disorders were found for TP53TG1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TP53TG1 Gene

Publications for TP53TG1 Gene

  1. Isolation of a novel TP53 target gene from a colon cancer cell line carrying a highly regulated wild-type TP53 expression system. (PMID: 9713990) Takei Y. … Nakamura Y. (Genes Chromosomes Cancer 1998) 2 3 4 64
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 64
  3. Analysis of functional variants reveals new candidate genes associated with alexithymia. (PMID: 25882097) Mezzavilla M. … Robino A. (Psychiatry Res 2015) 3 64
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  5. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 46 64

Products for TP53TG1 Gene

Sources for TP53TG1 Gene

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