Aliases for TP53INP2 Gene
External Ids for TP53INP2 Gene
Previous HGNC Symbols for TP53INP2 Gene
Previous GeneCards Identifiers for TP53INP2 Gene
GeneCards Summary for TP53INP2 Gene
TP53INP2 (Tumor Protein P53 Inducible Nuclear Protein 2) is a Protein Coding gene. An important paralog of this gene is TP53INP1.
UniProtKB/Swiss-Prot for TP53INP2 Gene
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.