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Aliases for TP53I13 Gene

Aliases for TP53I13 Gene

  • Tumor Protein P53 Inducible Protein 13 2 3
  • Damage-Stimulated Cytoplasmic Protein 1 3 4
  • DSCP1 3 4
  • Tumor Protein P53-Inducible Protein 13 3

External Ids for TP53I13 Gene

Previous GeneCards Identifiers for TP53I13 Gene

  • GC17P024920
  • GC17P027895
  • GC17P024125

Summaries for TP53I13 Gene

GeneCards Summary for TP53I13 Gene

TP53I13 (Tumor Protein P53 Inducible Protein 13) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TP53I13 Gene

  • May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TP53I13 Gene

Genomics for TP53I13 Gene

Regulatory Elements for TP53I13 Gene

Genomic Location for TP53I13 Gene

Start:
29,566,052 bp from pter
End:
29,573,157 bp from pter
Size:
7,106 bases
Orientation:
Plus strand

Genomic View for TP53I13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TP53I13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TP53I13 Gene

Proteins for TP53I13 Gene

  • Protein details for TP53I13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NBR0-P5I13_HUMAN
    Recommended name:
    Tumor protein p53-inducible protein 13
    Protein Accession:
    Q8NBR0
    Secondary Accessions:
    • Q7L5U3

    Protein attributes for TP53I13 Gene

    Size:
    393 amino acids
    Molecular mass:
    42238 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TP53I13 Gene

Proteomics data for TP53I13 Gene at MOPED

Post-translational modifications for TP53I13 Gene

  • Glycosylation at Thr187, Thr190, Ser191, Ser224, and Ser226
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TP53I13 Gene

Domains for TP53I13 Gene

Protein Domains for TP53I13 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TP53I13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TP53I13: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TP53I13 Gene

Function for TP53I13 Gene

Molecular function for TP53I13 Gene

UniProtKB/Swiss-Prot Function: May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed.
UniProtKB/Swiss-Prot Induction: Up-regulated by genotoxic stresses of adriamycin and/or UV irradiation in a p53/TP53-dependent manner.

Phenotypes for TP53I13 Gene

GenomeRNAi human phenotypes for TP53I13:
genes like me logo Genes that share phenotypes with TP53I13: view

miRNA for TP53I13 Gene

miRTarBase miRNAs that target TP53I13

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TP53I13 Gene

Localization for TP53I13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TP53I13 Gene

Cell membrane; Single-pass type I membrane protein; Extracellular side. Cytoplasm. Note=Associates with unknown subcellular structures in the cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TP53I13 Gene COMPARTMENTS Subcellular localization image for TP53I13 gene
Compartment Confidence
plasma membrane 5
extracellular 2
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TP53I13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TP53I13: view

Pathways for TP53I13 Gene

SuperPathways for TP53I13 Gene

No Data Available

Interacting Proteins for TP53I13 Gene

Gene Ontology (GO) - Biological Process for TP53I13 Gene

None

No data available for Pathways by source for TP53I13 Gene

Transcripts for TP53I13 Gene

Unigene Clusters for TP53I13 Gene

Tumor protein p53 inducible protein 13:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TP53I13 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11
SP1: - -
SP2: - - - - -
SP3: - - - - -
SP4: - - -
SP5: - - - -
SP6: - - - -
SP7: - -
SP8:

Relevant External Links for TP53I13 Gene

GeneLoc Exon Structure for
TP53I13
ECgene alternative splicing isoforms for
TP53I13

Expression for TP53I13 Gene

mRNA expression in normal human tissues for TP53I13 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TP53I13 Gene

SOURCE GeneReport for Unigene cluster for TP53I13 Gene Hs.514050

mRNA Expression by UniProt/SwissProt for TP53I13 Gene

Q8NBR0-P5I13_HUMAN
Tissue specificity: Expressed in heart, placenta, skeletal muscle, testis, brain and lung
genes like me logo Genes that share expressions with TP53I13: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for TP53I13 Gene

Orthologs for TP53I13 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TP53I13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TP53I13 35
  • 96.99 (n)
  • 95.33 (a)
TP53I13 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TP53I13 35
  • 82.96 (n)
  • 76.94 (a)
TP53I13 36
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TP53I13 35
  • 80.72 (n)
  • 71.89 (a)
TP53I13 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Trp53i13 35
  • 78.45 (n)
  • 71.82 (a)
Trp53i13 16
Trp53i13 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TP53I13 36
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tp53i13 35
  • 78.51 (n)
  • 72.18 (a)
lizard
(Anolis carolinensis)
Reptilia TP53I13 36
  • 52 (a)
OneToOne
Species with no ortholog for TP53I13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TP53I13 Gene

ENSEMBL:
Gene Tree for TP53I13 (if available)
TreeFam:
Gene Tree for TP53I13 (if available)

Paralogs for TP53I13 Gene

Selected SIMAP similar genes for TP53I13 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with TP53I13: view

No data available for Paralogs for TP53I13 Gene

Variants for TP53I13 Gene

Sequence variations from dbSNP and Humsavar for TP53I13 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs565977 -- 29,571,810(+) TCTTG(C/T)TTGTC intron-variant
rs569849 -- 29,569,423(+) GCAGC(C/G)TTCGC intron-variant
rs578733 -- 29,569,423(-) CGAAG(C/G)CTGCT intron-variant
rs6505139 -- 29,569,713(+) TGTGG(A/G)CCCCA intron-variant
rs8081201 -- 29,571,078(+) GAGTT(A/C)TTTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TP53I13 Gene

Variant ID Type Subtype PubMed ID
nsv833409 CNV Gain 17160897
nsv908033 CNV Loss 21882294
nsv521557 CNV Loss 19592680
dgv3135n71 CNV Loss 21882294
esv22811 CNV Loss 19812545

Relevant External Links for TP53I13 Gene

HapMap Linkage Disequilibrium report
TP53I13
Human Gene Mutation Database (HGMD)
TP53I13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TP53I13 Gene

Disorders for TP53I13 Gene

No disorders were found for TP53I13 Gene.

No data available for UniProtKB/Swiss-Prot for TP53I13 Gene

Publications for TP53I13 Gene

  1. DSCP1, a novel TP53-inducible gene, is upregulated by strong genotoxic stresses and its overexpression inhibits tumor cell growth in vitro. (PMID: 14767535) Hata T. … Furukawa T. (Int. J. Oncol. 2004) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TP53I13 Gene

Sources for TP53I13 Gene

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