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TOR1B Gene

protein-coding   GIFtS: 57
GCID: GC09P132565

Torsin Family 1, Member B (Torsin B)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Torsin Family 1, Member B (Torsin B)1 2
DQ12 3 5
Torsin Family 1 Member B2 3
torsin-1B2

External Ids:    HGNC: 119951   Entrez Gene: 273482   Ensembl: ENSG000001368167   OMIM: 6080505   UniProtKB: O146573   

Export aliases for TOR1B gene to outside databases

Previous GC identifers: GC09P123680 GC09P124211 GC09P126019 GC09P127941 GC09P129644 GC09P131605 GC09P102164


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TOR1B Gene:
TOR1B (torsin family 1, member B (torsin B)) is a protein-coding gene. Diseases associated with TOR1B include focal dystonia, and torsion dystonia. GO annotations related to this gene include unfolded protein binding and nucleoside-triphosphatase activity. An important paralog of this gene is TOR1A.

UniProtKB/Swiss-Prot: TOR1B_HUMAN, O14657
Function: May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TOR1B gene promoter:
         HOXA9B   HOXA9   C/EBPbeta   RFX1   HOXA3   AP-1   HNF-3beta   AREB6   SEF-1 (1)   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOR1B promoter sequence
   Search Chromatin IP Primers for TOR1B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TOR1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34

TOR1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOR1B gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P132565:  view genomic region     (about GC identifiers)

Start:
132,565,432 bp from pter      End:
132,573,560 bp from pter
Size:
8,129 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TOR1B_HUMAN, O14657 (See protein sequence)
Recommended Name: Torsin-1B precursor  
Size: 336 amino acids; 37979 Da

Explore the universe of human proteins at neXtProt for TOR1B: NX_O14657

Explore proteomics data for TOR1B at MOPED

Post-translational modifications: 

  • Glycosylation2 at Ser38, Thr41, Asn64, Asn165
  • Modification sites at PhosphoSitePlus

  • See TOR1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055321.1  
    ENSEMBL proteins: 
     ENSP00000259339   ENSP00000411912  

    TOR1B Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR017378 Torsin_subgr
     IPR027417 P-loop_NTPase
     IPR003593 AAA+_ATPase
     IPR010448 Torsin

    Graphical View of Domain Structure for InterPro Entry O14657

    ProtoNet protein and cluster: O14657

    1 Blocks protein domain: IPB010448 Torsin

    UniProtKB/Swiss-Prot: TOR1B_HUMAN, O14657
    Similarity: Belongs to the ClpA/ClpB family. Torsin subfamily


    TOR1B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TOR1B_HUMAN, O14657
    Function: May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins
    (By similarity)

         Genatlas biochemistry entry for TOR1B:
    torsin 1B ATP binding protein,homolog to TOR1A,and tightly linked to it in opposite orientation

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0016887ATPase activity IDA--
    GO:0017111nucleoside-triphosphatase activity ----
    GO:0051082unfolded protein binding TAS9288096
         
    TOR1B for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TOR1B
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    miRNA
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    miRTarBase miRNAs that target TOR1B:
    hsa-mir-192-5p (MIRT026354), hsa-mir-215-5p (MIRT024853), hsa-mir-26b-5p (MIRT029285)

    Block miRNA regulation of human, mouse, rat TOR1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TOR1B (see all 12):
    hsa-miR-137 hsa-miR-4288 hsa-miR-876-5p hsa-miR-632 hsa-miR-1205 hsa-miR-888 hsa-miR-3167 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidTOR1B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TOR1B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOR1B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TOR1B_HUMAN, O14657: Endoplasmic reticulum lumen (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum5
    cytoskeleton2
    cytosol2
    extracellular2
    nucleus2
    lysosome1
    peroxisome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope IEA--
    GO:0005737cytoplasm ----
    GO:0005783endoplasmic reticulum ----
    GO:0005788endoplasmic reticulum lumen IDA--
    GO:0070062extracellular vesicular exosome IDA19199708

    TOR1B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TOR1B
    Interactions:

        Search GeneGlobe Interaction Network for TOR1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for TOR1B (O146573 ENSP000002593394) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    H2AFXP161043, ENSP000003643104I2D: score=2 STRING: ENSP00000364310
    TOR1AO146563, ENSP000003457194I2D: score=3 STRING: ENSP00000345719
    TOR1AIP1ENSP000002715834STRING: ENSP00000271583
    NAGLUENSP000002259274STRING: ENSP00000225927
    DNAJC3ENSP000003659914STRING: ENSP00000365991
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006200ATP catabolic process IDA--
    GO:0006986response to unfolded protein TAS10644435
    GO:0051085chaperone mediated protein folding requiring cofactor IEA--
    GO:0051260protein homooligomerization IDA--
    GO:0071763nuclear membrane organization IEA--

    TOR1B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TOR1B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TOR1B gene: 
    NM_014506.1  

    Unigene Cluster for TOR1B:

    Torsin family 1, member B (torsin B)
    Hs.252682  [show with all ESTs]
    Unigene Representative Sequence: NM_014506
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000259339(uc004byk.1) ENST00000486372 ENST00000427860 ENST00000488169

    miRNA
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    Block miRNA regulation of human, mouse, rat TOR1B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TOR1B (see all 12):
    hsa-miR-137 hsa-miR-4288 hsa-miR-876-5p hsa-miR-632 hsa-miR-1205 hsa-miR-888 hsa-miR-3167 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidTOR1B 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: TOR1B (NM_014506)
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    OriGene qPCR primer pairs and template standards for TOR1B
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TOR1B
      QuantiTect SYBR Green Assays in human, mouse, rat TOR1B
      QuantiFast Probe-based Assays in human, mouse, rat TOR1B

    Additional mRNA sequence: 

    AF007872.1 AF317129.1 BC006480.1 BC015578.2 

    11 DOTS entries:

    DT.316343  DT.316344  DT.92454479  DT.121191278  DT.102823660  DT.95235004  DT.121191224  DT.92454475 
    DT.95082154  DT.95082153  DT.95113799 

    Selected AceView cDNA sequences (see all 177):

    AI336026 BE893335 CB529771 AA627547 AL044942 BC006480 BM839263 BM982572 
    F12854 AA040879 BQ669219 N46242 AA834420 AA973647 AI493923 BM715538 
    AW877039 AA610045 AW768777 BU543176 AI815528 BC015578 AW160403 CB528968 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TOR1B (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b
    SP1:              -                             -                       -                           
    SP2:                                      -     -                       -                           
    SP3:                                                                    -                           
    SP4:              -                                   -                                             
    SP5:              -                             -     -     -     -     -     -     -               


    ECgene alternative splicing isoforms for TOR1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TOR1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAATGCCTT
    TOR1B Expression
    About this image


    TOR1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    TOR1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TOR1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.252682

    UniProtKB/Swiss-Prot: TOR1B_HUMAN, O14657
    Tissue specificity: Widely expressed with low levels in brain. Not detected in fetal brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TOR1B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tor1b1 , 5 torsin family 1, member B1, 5 86.75(n)1
    91.35(a)1
      2 (21.76 cM)5
    309341  NM_133673.31  NP_598434.21 
     309529595 
    chicken
    (Gallus gallus)
    Aves TOR1B1 torsin family 1, member B (torsin B) 72.22(n)
    73.4(a)
      417191  XM_415473.4  XP_415473.3 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.14102 Transcribed sequence with weak similarity to protein more 74.08(n)    BX716960.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj81e012 Danio rerio, similar to torsion, clone IMAGE5916314, more 76.11(n)    BC050957.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta torp4a3 protein folding chaperone 35(a)   4C11   --
    worm
    (Caenorhabditis elegans)
    Secernentea tor-21 , 3 tor-21 41(a)
    (best of 2)3
    50.65(n)1
    42.4(a)1
      IV(13982853-13984335)3
    1896061  NM_070282.11  NP_502683.11 


    ENSEMBL Gene Tree for TOR1B (if available)
    TreeFam Gene Tree for TOR1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TOR1B gene
    TOR1A2  TOR2A2  TOR4A2  TOR3A2  
    3 SIMAP similar genes for TOR1B using alignment to 3 protein entries:     TOR1B_HUMAN (see all proteins):
    TOR1A    TOR3A    TOR2A

    TOR1B for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TOR1B
    PGOHUM00000240098


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TOR1B (see all 258)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1894016511,2
    --132563525(+) ACCCAA/GCAGCC 1 -- us2k10--------
    rs1435002561,2
    --132563784(+) GCCCAC/GCTTAG 1 -- us2k10--------
    rs1811551891,2
    --132563802(+) CCTTCC/TCTGTA 1 -- us2k10--------
    rs1471492101,2
    C--132564025(+) GGGGCC/TGCTGC 1 -- us2k10--------
    rs789022641,2
    C,F--132564070(+) AGTTCG/ACAACT 1 -- us2k11Minor allele frequency- A:0.25WA 118
    rs1995568931,2
    C--132564198(+) ACAAAC/TCCAGC 1 -- us2k10--------
    rs1403138801,2
    C--132564205(+) CAGCCA/GTAAGC 1 -- us2k10--------
    rs1492378041,2
    --132564256(+) AGATCG/TCTTGA 1 -- us2k10--------
    rs1180387791,2
    C,F--132564286(+) GCTTGG/CGCCAC 1 -- us2k11Minor allele frequency- C:0.07EA 120
    rs1856649251,2
    --132564338(+) GGGCGC/TGTTGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TOR1B (132565432 - 132573560 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TOR1B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6729CNV Insertion18451855
    nsv893925CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TOR1B
    DNA2.0 Custom Variant and Variant Library Synthesis for TOR1B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608050    OMIM disorders: --

    4 diseases for TOR1B:    
    About MalaCards
    focal dystonia    torsion dystonia    hepatocellular carcinoma    cerebritis


    TOR1B for disorders           About GeneDecksing

    Genetic Association Database (GAD): TOR1B
    Human Genome Epidemiology (HuGE) Navigator: TOR1B (2 documents)

    Export disorders for TOR1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TOR1B gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TOR1B)
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    1. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. (PubMed id 9288096)1, 2, 3 Ozelius L.J.... Breakefield X.O. (Nat. Genet. 1997)
    2. The TOR1A (DYT1) gene family and its role in early onset torsion dystonia. (PubMed id 10644435)1, 3, 9 Ozelius L.J....Breakefield X.O. (Genomics 1999)
    3. Genetic evidence for an association of the TOR1A locus with segmental/focal dystonia. (PubMed id 20669276)1, 4 Sharma N....Ozelius L.J. (Mov. Disord. 2010)
    4. Strong genetic evidence for association of TOR1A/TOR1B with idiopathic dystonia. (PubMed id 17130424)1, 4 Kamm C....Gasser T. (Neurology 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    7. Arresting a Torsin ATPase reshapes the endoplasmic reticulum. (PubMed id 24275647)1 Rose A.E....Schlieker C. (J. Biol. Chem. 2014)
    8. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (J. Proteome Res. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma. (PubMed id 20000738)1 Yang X....Chen X. (J. Proteome Res. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27348 HGNC: 11995 AceView: TOR1B Ensembl:ENSG00000136816 euGenes: HUgn27348
    ECgene: TOR1B H-InvDB: TOR1B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TOR1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TOR1B gene:
    Search GeneIP for patents involving TOR1B

    GeneCards and IP:
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