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TOR1AIP1 Gene

protein-coding   GIFtS: 53
GCID: GC01P179851

Torsin A Interacting Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Torsin A Interacting Protein 11 2     LAP12 5
LAP1B2 3 5     Lamina-Associated Polypeptide 1B2
Lamina Associated Polypeptide 1B1 2     Torsin-1A-Interacting Protein 12
Lamin-Associated Protein 1B2 3     

External Ids:    HGNC: 294561   Entrez Gene: 260922   Ensembl: ENSG000001433377   OMIM: 6145125   UniProtKB: Q5JTV83   

Export aliases for TOR1AIP1 gene to outside databases

Previous GC identifers: GC01P176583 GC01P178118 GC01P151084


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TOR1AIP1 Gene:
This gene encodes a type 2 integral membrane protein that binds A- and B-type laminins. The encoded protein
localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane
to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. (provided
by RefSeq, Jun 2012)

GeneCards Summary for TOR1AIP1 Gene:
TOR1AIP1 (torsin A interacting protein 1) is a protein-coding gene. Diseases associated with TOR1AIP1 include breast and colorectal cancer, and tonsillitis. GO annotations related to this gene include lamin binding. An important paralog of this gene is TOR1AIP2.

UniProtKB/Swiss-Prot: TOIP1_HUMAN, Q5JTV8
Function: Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
Induces TOR1A and TOR1B ATPase activity

Gene Wiki entry for TOR1AIP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TOR1AIP1 gene promoter:
         RFX1   MAZR   Pax-5   ATF-2   RORalpha2   GATA-2   ARP-1   FOXO1a   Pax-4a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOR1AIP1 promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TOR1AIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.2   Ensembl cytogenetic band:  1q25.2   HGNC cytogenetic band: 1q24.2

TOR1AIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOR1AIP1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P179851:  view genomic region     (about GC identifiers)

Start:
179,851,177 bp from pter      End:
179,894,135 bp from pter
Size:
42,959 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TOIP1_HUMAN, Q5JTV8 (See protein sequence)
Recommended Name: Torsin-1A-interacting protein 1  
Size: 583 amino acids; 66248 Da
Subunit: Interacts with ATP1B4. Interacts with TOR1A (ATP-bound)
Sequence caution: Sequence=AAH23247.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB13855.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14461.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAF84184.1; Type=Erroneous
initiation; Note=Translation N-terminally extended;
Secondary accessions: A8K630 B0QZ57 Q5JTV6 Q8IZ65 Q9H8Y6 Q9HAJ1 Q9NV52 Q9Y3X5
Alternative splicing: 2 isoforms:  Q5JTV8-1   Q5JTV8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TOR1AIP1: NX_Q5JTV8

Explore proteomics data for TOR1AIP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys274, Lys285, Lys308, Lys334, Lys556
  • Glycosylation2 at Asn399
  • Modification sites at PhosphoSitePlus

  • See TOR1AIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001254507.1  NP_056417.2  

    ENSEMBL proteins: 
     ENSP00000435365   ENSP00000271583   ENSP00000476687   ENSP00000393292   ENSP00000434316  
     ENSP00000432717   ENSP00000433759   ENSP00000393613  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008662 Lamina-ass_polypeptide_CLAP1C

    Graphical View of Domain Structure for InterPro Entry Q5JTV8

    ProtoNet protein and cluster: Q5JTV8

    UniProtKB/Swiss-Prot: TOIP1_HUMAN, Q5JTV8
    Similarity: Belongs to the TOR1AIP family


    TOR1AIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TOIP1_HUMAN, Q5JTV8
    Function: Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
    Induces TOR1A and TOR1B ATPase activity

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001671ATPase activator activity IDA--
    GO:0005515protein binding ----
    GO:0005521lamin binding ----
    GO:0051117ATPase binding IPI--
         
    TOR1AIP1 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tor1aip1):
     cellular  mortality/aging 

    TOR1AIP1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TOR1AIP1
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    miRNA
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    miRTarBase miRNAs that target TOR1AIP1:
    hsa-mir-192-5p (MIRT026145), hsa-mir-101-3p (MIRT027250), hsa-mir-215-5p (MIRT024930)

    Block miRNA regulation of human, mouse, rat TOR1AIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TOR1AIP1 (see all 32):
    hsa-miR-548j hsa-miR-330-5p hsa-miR-29b-1* hsa-miR-3162-5p hsa-miR-1304 hsa-miR-1276 hsa-miR-326 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidTOR1AIP1 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TOIP1_HUMAN, Q5JTV8: Nucleus inner membrane; Single-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005635nuclear envelope ----
    GO:0005637nuclear inner membrane IEA--
    GO:0016021integral component of membrane IEA--

    TOR1AIP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TOR1AIP1
    Interactions:

        Search GeneGlobe Interaction Network for TOR1AIP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for TOR1AIP1 (Q5JTV83 ENSP000002715834) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAP621363, ENSP000003260314I2D: score=1 STRING: ENSP00000326031
    LMNAP025453, ENSP000003572834I2D: score=4 STRING: ENSP00000357283
    LMNB1P207003, ENSP000002613664I2D: score=2 STRING: ENSP00000261366
    TOR1AENSP000003457194STRING: ENSP00000345719
    TOR1BENSP000002593394STRING: ENSP00000259339
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032781positive regulation of ATPase activity IDA--
    GO:0034504protein localization to nucleus ----
    GO:0071763nuclear membrane organization ----

    TOR1AIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TOR1AIP1 (TOIP1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TOR1AIP1 gene (3 alternative transcripts): 
    NM_001267578.1  NM_015602.3  NM_032678.1  

    Unigene Cluster for TOR1AIP1:

    Torsin A interacting protein 1
    Hs.496459  [show with all ESTs]
    Unigene Representative Sequence: NM_001267578
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000528443(uc001gnp.1) ENST00000271583(uc001gnq.3) ENST00000606911
    ENST00000435319 ENST00000531630 ENST00000527391 ENST00000529091 ENST00000527867
    ENST00000474875 ENST00000531726 ENST00000524653 ENST00000447964
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TOR1AIP1 (see all 32):
    hsa-miR-548j hsa-miR-330-5p hsa-miR-29b-1* hsa-miR-3162-5p hsa-miR-1304 hsa-miR-1276 hsa-miR-326 hsa-miR-3613-3p
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    Additional mRNA sequence: 

    AK001780.1 AK021613.1 AK023204.1 AK291495.1 AK310012.1 AL050126.1 BC023247.1 BC069736.1 

    19 DOTS entries:

    DT.414835  DT.102828647  DT.206217  DT.100823642  DT.91791112  DT.121385514  DT.100747219  DT.121385532 
    DT.91753968  DT.91753972  DT.92039054  DT.95089861  DT.100807005  DT.121385500  DT.95089862  DT.95089865 
    DT.97787950  DT.100801939  DT.91924106 

    Selected AceView cDNA sequences (see all 153):

    AL050126 AA885049 BX474778 AL548450 AU279959 BQ720485 CR591258 BM849599 
    BF901875 BM851429 BX369105 AL697726 BQ188330 BP873596 CR595831 CB145934 
    BM848939 AL597483 AA620740 NM_015602 BM852209 BM852229 BQ435161 AL597468 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TOR1AIP1    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b · 11c
    SP1:                    -     -                                                                     
    SP2:                    -     -                                                                     
    SP3:                                                                                                
    SP4:                                                                          -                     


    ECgene alternative splicing isoforms for TOR1AIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TOR1AIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTATTGCCC
    TOR1AIP1 Expression
    About this image


    TOR1AIP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    TOR1AIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TOR1AIP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.496459
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOR1AIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TOR1AIP1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tor1aip11 , 5 torsin A interacting protein 11, 5 78.26(n)1
    71.86(a)1
      1 (67.69 cM)5
    2082631  NM_001160018.11  NP_001153490.11 
     1560062345 
    chicken
    (Gallus gallus)
    Aves TOR1AIP16
    torsin A interacting protein 1
    41(a)
    1 ↔ 1
    8(6046688-6054768)
    lizard
    (Anolis carolinensis)
    Reptilia TOR1AIP16
    torsin A interacting protein 1
    27(a)
    1 ↔ 1
    4(70638378-70655513)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.2402 Transcribed sequence with weak similarity to protein more 72.65(n)    BX720486.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkeyp-82a1.66
    zgc:1129626
    zgc:112962
    23(a)
    16(a)
    many ↔ many
    many ↔ many
    8(21584836-21590389) ENSDARG00000094336
    8(21590491-21609772) ENSDARG00000069102


    ENSEMBL Gene Tree for TOR1AIP1 (if available)
    TreeFam Gene Tree for TOR1AIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TOR1AIP1 gene
    TOR1AIP22  
    1 SIMAP similar gene for TOR1AIP1 using alignment to 6 protein entries:     TOIP1_HUMAN (see all proteins):
    TOR1AIP2

    TOR1AIP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TOR1AIP1 (see all 918)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358184
    A breast cancer sample4--see VAR_0358182 V I mis40--------
    rs571370481,2
    C--151081050(+) TGTGT-/GTGTGT
            
    TAGCA
    2 -- us2k11Minor allele frequency- GTGTGT:0.00NA 2
    rs1130561301,2
    C--179849178(+) ATATATG/-TGTGT 2 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1485854051,2
    C--179849178(+) ATATA-/TGTGTG
            
    TGTGT
    2 -- us2k10--------
    rs1392160461,2
    C--179849243(+) TTTAC-/AGTA  
            
    AGTGT
    2 -- us2k10--------
    rs1847827361,2
    --179849311(+) CAAAAC/TATGCA 2 -- us2k10--------
    rs172795941,2
    C,F,H--179849356(+) CTCTGA/TTTGTT 2 -- us2k110Minor allele frequency- T:0.14NA NS EA 804
    rs1498948831,2
    --179849393(+) TTTAAC/TTTGTC 2 -- us2k10--------
    rs1450095381,2
    --179849695(+) TAAATC/TTAGCT 2 -- us2k10--------
    rs1490783261,2
    C--179849728(+) ATCCAA/GACTGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TOR1AIP1 (179851177 - 179894135 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TOR1AIP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv3744CNV Insertion18451855
    nsv518936CNV Gain19592680

    Human Gene Mutation Database (HGMD): TOR1AIP1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TOR1AIP1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 614512    OMIM disorders: --

    10 diseases for TOR1AIP1:    
    About MalaCards
    breast and colorectal cancer    tonsillitis    hiv-1    multiple myeloma
    myeloma    colorectal cancer    thyroiditis    cerebritis
    endotheliitis    prostatitis


    TOR1AIP1 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: TOR1AIP1 (1 document)

    Export disorders for TOR1AIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TOR1AIP1 gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with TOR1AIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein. (PubMed id 15767459)1, 2, 3 Goodchild R.E. and Dauer W.T. (J. Cell Biol. 2005)
    2. Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants. (PubMed id 12061773)1, 2, 3 Kondo Y.... Yoneda Y. (Biochem. Biophys. Res. Commun. 2002)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Effect of (211)At alpha-particle irradiation on expression of selected radiation responsive genes in human lymphocytes. (PubMed id 19382019)1, 9 Turtoi A. and Schneeweiss F.H. (Int. J. Radiat. Biol. 2009)
    8. Protein phosphatase 1I^ isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (J. Mol. Neurosci. 2013)
    9. Regulation of Torsin ATPases by LAP1 and LULL1. (PubMed id 23569223)2 Zhao C....Schlieker C. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 26092 HGNC: 29456 AceView: LAP1B Ensembl:ENSG00000143337 euGenes: HUgn26092
    ECgene: TOR1AIP1 H-InvDB: TOR1AIP1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TOR1AIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TOR1AIP1 gene:
    Search GeneIP for patents involving TOR1AIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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