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Aliases for TOP1P2 Gene

Subcategory (RNA class) for TOP1P2 Gene

antisense

Aliases for TOP1P2 Gene

  • Topoisomerase (DNA) I Pseudogene 2 2 3

External Ids for TOP1P2 Gene

ORGUL Members for TOP1P2 Gene

Previous GeneCards Identifiers for TOP1P2 Gene

  • GC22U990045
  • GC22P023485
  • GC22P025160
  • GC22P008108

Summaries for TOP1P2 Gene

GeneCards Summary for TOP1P2 Gene

TOP1P2 (Topoisomerase (DNA) I Pseudogene 2) is a Pseudogene, and is affiliated with the antisense RNA class.

fRNAdb sequence ontologies for TOP1P2 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for TOP1P2

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for TOP1P2 Gene

Genomics for TOP1P2 Gene

Regulatory Elements for TOP1P2 Gene

Enhancers for TOP1P2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G024726 1.4 Ensembl ENCODE 0.3 -35.4 -35410 4.6 PKNOX1 FOXA2 MLX CREB3L1 ARNT ZFP64 ARID4B FEZF1 DMAP1 ZNF2 GC22P024759 TOP1P2
GH22G024772 0.7 ENCODE 0.4 +8.2 8188 0.2 CTCF ZNF654 MAX REST RAD21 JUND ATF3 IKZF1 ZNF143 SMC3 PIWIL3 TOP1P2
GH22G024758 0.7 ENCODE 0.4 -6.1 -6133 0.2 CTCF ZNF654 TRIM22 CEBPG REST RAD21 ZNF592 RFX5 GATA3 CEBPA TOP1P2 GC22P024759
GH22G024731 0.4 ENCODE 0.3 -32.5 -32493 0.0 JUN FOS GC22P024759 TOP1P2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TOP1P2 on UCSC Golden Path with GeneCards custom track

Genomic Location for TOP1P2 Gene

Chromosome:
22
Start:
24,764,501 bp from pter
End:
24,766,021 bp from pter
Size:
1,521 bases
Orientation:
Plus strand

Genomic View for TOP1P2 Gene

Genes around TOP1P2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TOP1P2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TOP1P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TOP1P2 Gene

ORGUL Member Location for TOP1P2 Gene

ORGUL Member Location for TOP1P2 gene

Proteins for TOP1P2 Gene

Post-translational modifications for TOP1P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TOP1P2 Gene

Domains & Families for TOP1P2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TOP1P2 Gene

Function for TOP1P2 Gene

Molecular function for TOP1P2 Gene

GENATLAS Biochemistry:
DNA topoisomerase I,pseudogene 2

Animal Model Products

miRNA for TOP1P2 Gene

miRTarBase miRNAs that target TOP1P2

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TOP1P2 Gene

Localization for TOP1P2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TOP1P2 Gene

Pathways & Interactions for TOP1P2 Gene

SuperPathways for TOP1P2 Gene

No Data Available

Interacting Proteins for TOP1P2 Gene

Gene Ontology (GO) - Biological Process for TOP1P2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TOP1P2 Gene

Drugs & Compounds for TOP1P2 Gene

No Compound Related Data Available

Transcripts for TOP1P2 Gene

fRNAdb Secondary structures for TOP1P2 Gene

  • FR326845

mRNA/cDNA for TOP1P2 Gene

(2) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:

Unigene Clusters for TOP1P2 Gene

Topoisomerase (DNA) I pseudogene 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TOP1P2 Gene

No ASD Table

Relevant External Links for TOP1P2 Gene

GeneLoc Exon Structure for
TOP1P2
ECgene alternative splicing isoforms for
TOP1P2

Expression for TOP1P2 Gene

NURSA nuclear receptor signaling pathways regulating expression of TOP1P2 Gene:

TOP1P2

SOURCE GeneReport for Unigene cluster for TOP1P2 Gene:

Hs.381281
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TOP1P2 Gene

Orthologs for TOP1P2 Gene

No data available for Orthologs and Evolution for TOP1P2 Gene

Paralogs for TOP1P2 Gene

No data available for Paralogs for TOP1P2 Gene

Variants for TOP1P2 Gene

Sequence variations from dbSNP and Humsavar for TOP1P2 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1002239918 -- 24,766,180(+) CGGGG(C/T)TTCAC intron-variant, downstream-variant-500B
rs1004021721 -- 24,764,502(+) AGGTG(A/G)ATCCG intron-variant, nc-transcript-variant
rs1004686603 -- 24,764,205(+) AAGAG(A/G)CCACG intron-variant, upstream-variant-2KB
rs1005206991 -- 24,764,129(+) CAGGC(A/G)TCGCC intron-variant, upstream-variant-2KB
rs1006176775 -- 24,762,851(+) AGGCA(G/T)GGAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TOP1P2 Gene

Variant ID Type Subtype PubMed ID
nsv1110863 OTHER inversion 24896259
nsv7350 OTHER inversion 18451855
nsv962778 CNV duplication 23825009

Relevant External Links for TOP1P2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TOP1P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TOP1P2 Gene

Disorders for TOP1P2 Gene

Relevant External Links for TOP1P2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TOP1P2

No disorders were found for TOP1P2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TOP1P2 Gene

Publications for TOP1P2 Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3 64
  2. Molecular structures of two human DNA topoisomerase I retrosequences. (PMID: 2170234) Yang G.C. … Richter A. (Gene 1990) 3 64
  3. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang K.C. … Mattick J.S. (Nucleic Acids Res. 2005) 1
  4. Mapping of conserved RNA secondary structures predicts thousands of functional noncoding RNAs in the human genome. (PMID: 16273071) Washietl S. … Stadler P.F. (Nat. Biotechnol. 2005) 1

Products for TOP1P2 Gene

Sources for TOP1P2 Gene

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