Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TOMM7 Gene

protein-coding   GIFtS: 50
GCID: GC07M022818

translocase of outer mitochondrial membrane 7 homolog (yeast)

  Search for TOMM7
in our new
 Human Malady Compendium 
Biological research products
for TOMM7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Translocase Of Outer Mitochondrial Membrane 7 Homolog (Yeast)1 2
Translocase Of Outer Membrane 7 KDa Subunit Homolog2 3
TOM72 3
6.2 Kd Protein2
Mitochondrial Import Receptor Subunit TOM7 Homolog2
TOMM073

External Ids:    HGNC: 216481   Entrez Gene: 545432   Ensembl: ENSG000001966837   OMIM: 6079805   UniProtKB: Q9P0U13   

Export aliases for TOMM7 gene to outside databases

Previous GC identifers: GC07M022560 GC07M022594 GC07M022626 GC07M022735


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TOMM7:
This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the
assembly and stability of the translocase complex. (provided by RefSeq, Oct 2012)

UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1
Function: Required for assembly and stability of the TOM complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TOMM7 gene promoter:
         ISGF-3   LHX3b/Lhx3b   Pbx1a   POU3F1   Evi-1   E47   HFH-1   LHX3a/Lhx3a   Hand1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOMM7 promoter sequence
   Search SABiosciences Chromatin IP Primers for TOMM7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TOMM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.3   Ensembl cytogenetic band:  7p15.3   HGNC cytogenetic band: 7p15.3

TOMM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOMM7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M022818:  view genomic region     (about GC identifiers)

Start:
22,852,251 bp from pter      End:
22,862,470 bp from pter
Size:
10,220 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 22,903,376-22,913,545     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1 (See protein sequence)
Recommended Name: Mitochondrial import receptor subunit TOM7 homolog  
Size: 55 amino acids; 6248 Da
Subunit: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which
consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70)
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein
Secondary accessions: O95939

Explore the universe of human proteins at neXtProt for TOMM7: NX_Q9P0U1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9P0U1

  • TOMM7 Protein expression data from MOPED and PaxDb:    About this image 
    TOMM7 Protein Expression
    REFSEQ proteins: NP_061932.1  
    ENSEMBL proteins: 
     ENSP00000351214   ENSP00000385203   ENSP00000361970  
    Reactome Protein details: Q9P0U1
    Human Recombinant Protein Products for TOMM7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: TOMM7
    OriGene Custom Protein Services for TOMM7 
    GenScript Custom Purified and Recombinant Proteins Services for TOMM7
    Novus Biologicals TOMM7 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TOMM7

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA12198123
    GO:0005741mitochondrial outer membrane ----
    GO:0005742mitochondrial outer membrane translocase complex IDA12198123
    GO:0016021integral to membrane IEA--

    TOMM7 for ontologies           About GeneDecksing



    TOMM7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TOMM7 
    GenScript Custom Superior Antibodies Services for TOMM7
    Search for Antibodies for TOMM7 at Abcam  
    Uscn Antibodies for TOMM7
    Search ThermoFisher Antibodies for TOMM7

    Assay Products for TOMM7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TOMM7
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TOMM7


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TOMM7 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR012621 Tom7

    Graphical View of Domain Structure for InterPro Entry Q9P0U1

    ProtoNet protein and cluster: Q9P0U1

    1 Blocks protein family: IPB012621 TOM7

    UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1
    Similarity: Belongs to the Tom7 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TOM7_HUMAN, Q9P0U1
    Function: Required for assembly and stability of the TOM complex

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12198123
    GO:0008320protein transmembrane transporter activity TAS15644312
    GO:0015450P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA--
         
    TOMM7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TOMM7 

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: TOMM7
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TOMM7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TOMM7
    SwitchGear 3'UTR luciferase reporter plasmidTOMM7 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TOMM7 (see all 7)
    OriGene shRNA RFP: TOMM7
    OriGene siRNA: TOMM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TOMM7
    Sirion Biotech Custom design and validation of potent shRNA sequences against TOMM7 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TOMM7
    Sirion Biotech Customized adenovirus for overexpression of TOMM7 
    Sirion Biotech Customized adenovirus for potent knockdown of TOMM7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TOMM7 (NM_014820)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TOMM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TOMM7
    Search LifeMap BioReagents cell lines for TOMM7
    Sirion Biotech Customized stable knockdown cell line services for TOMM7 
    Sirion Biotech Customized inducible knockdown cell line services for TOMM7
    Sirion Biotech Customized stable overexpressing cell line services for TOMM7
    Sirion Biotech Customized inducible overexpressing cell line services for TOMM7

    In Situ Assay
    Products:
       

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TOMM7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Mitochondrial Protein Import
    Mitochondrial Protein Import1.00
    2Asparagine N-linked glycosylation
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for TOMM7
        Mitochondrial Protein Import
    Metabolism of proteins



    TOMM7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TOMM7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/27 Interacting proteins for TOMM7 (Q9P0U11, 3 ENSP000003512144) via UniProtKB, MINT, STRING, and/or I2D (see all 27)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TOMM22Q9NS691, 3, ENSP000002160344EBI-1180558,EBI-1180569 I2D: score=2 STRING: ENSP00000216034
    TOMM40O960083, ENSP000002524874I2D: score=2 STRING: ENSP00000252487
    DNAJC19ENSP000003720054STRING: ENSP00000372005
    GRPEL1ENSP000002649544STRING: ENSP00000264954
    MTX1ENSP000003573604STRING: ENSP00000357360
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS15644312
    GO:0006886intracellular protein transport ----
    GO:0044267cellular protein metabolic process TAS--

    TOMM7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TOMM7
    Search CenterWatch for drugs/clinical trials and news about TOMM7 / TOM7 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TOMM7 gene: 
    NM_019059.3  

    Unigene Cluster for TOMM7:

    Translocase of outer mitochondrial membrane 7 homolog (yeast)
    Hs.112318  [show with all ESTs]
    Unigene Representative Sequence: CD048567
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000463284 ENST00000358435(uc003svk.3) ENST00000483581 ENST00000405021
    ENST00000372879 ENST00000496129

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: TOMM7
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TOMM7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TOMM7
    SwitchGear 3'UTR luciferase reporter plasmidTOMM7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TOMM7 (see all 7)
    OriGene shRNA RFP: TOMM7
    OriGene siRNA: TOMM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TOMM7
    Sirion Biotech Custom design and validation of potent shRNA sequences against TOMM7 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TOMM7 (NM_014820)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TOMM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM7 
    Primer
    Products:
        
    Browse OriGene genome-wide validated SYBR primer pairs
    Browse OriGene validated miRNA SYBR primer pairs
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat TOMM7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TOMM7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TOMM7

    Additional cDNA sequence: 

    AF086336.1 AF150733.1 AJ011007.1 AK026520.1 BC001732.1 BC071973.1 CR456960.1 

    15 DOTS entries:

    DT.100861392  DT.87017313  DT.102829396  DT.100689421  DT.120878158  DT.100806946  DT.100009074  DT.100057581 
    DT.121049623  DT.87001802  DT.92475107  DT.40286998  DT.95288390  DT.100891992  DT.121049619 

    24/652 AceView cDNA sequences (see all 652):

    AA864985 BG760143 BM764622 AA320314 AA640125 BQ670128 BQ935404 BE731106 
    AA872028 BQ056695 AA983421 F30546 BG761632 AA385602 AA516008 F36124 
    AI022931 BQ683453 F25361 AA314957 CR599481 BU164304 F31370 F34876 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TOMM7    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b
    SP1:                          -     -               
    SP2:                          -                     
    SP3:                    -     -     -               
    SP4:                                                


    ECgene alternative splicing isoforms for TOMM7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TOMM7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAGATGTGT
    TOMM7 Expression
    About this image
    See TOMM7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TOMM7

    SOURCE GeneReport for Unigene cluster: Hs.112318
        SABiosciences Custom PCR Arrays for TOMM7

    Primer
    Products:
    Browse OriGene genome-wide validated SYBR primer pairs
    Browse OriGene validated miRNA SYBR primer pairs
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat TOMM7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TOMM7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TOMM7
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TOMM7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TOMM7 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tomm71 , 5 translocase of outer mitochondrial membrane 7 homolog more1, 5 90.3(n)1
    94.55(a)1
      5 (10.48 cM)5
    661691  NM_025394.31  NP_079670.11 
     238389445 
    chicken
    (Gallus gallus)
    Aves TOMM71 translocase of outer mitochondrial membrane 7 homolog more 80.61(n)
    87.27(a)
      420610  NM_001199617.1  NP_001186546.1 
    lizard
    (Anolis carolinensis)
    Reptilia TOMM76
    --
    82(a)
    1 ↔ 1
    6(30314884-30321641)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253772 Xenopus laevis transcribed sequence with moderate similarity more 73.74(n)    BJ051727.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tomm71 translocase of outer mitochondrial membrane 7 homolog more 76.97(n)
    83.64(a)
      751649  NM_001161487.1  NP_001154959.1 


    ENSEMBL Gene Tree for TOMM7 (if available)
    TreeFam Gene Tree for TOMM7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TOMM7 gene
    1 SIMAP similar gene for TOMM7 using alignment to 3 protein entries:     TOM7_HUMAN (see all proteins):
    TOM7

    TOMM7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for TOMM7
    PGOHUM00000245628 PGOHUM00000235547


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/268 NCBI SNPs in TOMM7 are shown (see all 268    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs732782661,2
    C--22851877(+) CCCAAC/TAGGCT 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs171472901,2
    C,F,H--22851967(+) TAGAAG/AAACGG 1 -- ds50018Minor allele frequency- A:0.15NA NS WA EA 694
    rs1812107961,2
    --22851970(+) AAGAAC/TGGAAA 1 -- ds50010--------
    rs1866662791,2
    --22851989(+) TAATAA/GAAGTA 1 -- ds50010--------
    rs1449771291,2
    --22852049(+) AACTAC/GTTTCC 1 -- ds50010--------
    rs1125994041,2
    C--22852424(+) AAAAAT/ATTTTT 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs778936811,2
    F--22852436(+) ATATCG/ATGATC 1 -- ut311Minor allele frequency- A:0.06WA 118
    rs22407281,2
    C,F--22852499(-) TGTGTA/GTACCT 1 -- ut31 ese312Minor allele frequency- G:0.42NA WA CSA EA 376
    rs22407271,2
    C,F,H--22852512(-) AACAGA/GGAATT 1 -- ut31 ese323Minor allele frequency- G:0.45EA NS NA WA CSA 3832
    rs10544711,2
    C,F,A,H--22852643(-) GTGGAA/TCTTGT 1 -- ut3196Minor allele frequency- T:0.48EA NS MN NA PA EU CA WA CSA 5990

    HapMap Linkage Disequilibrium report for TOMM7 (22852251 - 22862470 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for TOMM7
         1 CNV: 3670
         1 Indel: 99890

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TOMM7
    DNA2.0 Custom Variant and Variant Library Synthesis for TOMM7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TOMM7 for disorders           About MalaCards

    TOMM7 for disorders           About GeneDecksing

    OMIM gene information: 607980    OMIM disorders: --

    Human Genome Epidemiology (HuGE) Navigator: TOMM7 (2 documents)

    Export disorders for TOMM7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TOMM7 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with TOMM7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane. (PubMed id 12198123)1, 2, 3 Johnston A.J.... Ryan M.T. (2002)
    2. Cloning and characterization of the human novel gene encoding 6.2 kDa protein highly expressed upon ultraviolet irradiation in DNA-PK- deleted human glioma M059J cells. (PubMed id 10647823)1, 2, 3 Lee J.-S. (1999)
    3. Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane. (PubMed id 18331822)1, 2, 9 Kato H. and Mihara K. (2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54543 HGNC: 21648 AceView: TOMM7 Ensembl:ENSG00000196683 euGenes: HUgn54543
    ECgene: TOMM7 H-InvDB: TOMM7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TOMM7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TOMM7 gene:
    Search GeneIP for patents involving TOMM7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for TOMM7  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TOMM7   Browse OriGene genome-wide validated SYBR primer pairs  
     OriGene Protein Over-expression Lysate for TOMM7   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TOMM7   OriGene 3'-UTR Clone for TOMM7  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TOMM7  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TOMM7   OriGene Custom Protein Services for TOMM7  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TOMM7
     Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TOMM7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TOMM7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TOMM7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TOMM7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TOMM7
     GenScript Custom Purified and Recombinant Proteins Services for TOMM7 GenScript cDNA clones with any tag delivered in your preferred vector for TOMM7
     GenScript Custom Assay Services for TOMM7 GenScript Custom Superior Antibodies Services for TOMM7
     GenScript Custom overexpressing Cell Line Services for TOMM7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TOMM7 promoter
     Search Chromatin IP Primers for TOMM7
     Search RT2 qPCR Primer Assays in human, mouse, rat TOMM7
     Search GNC Networks for TOMM7
     SABiosciences Custom PCR Arrays for TOMM7
     Search Tocris compounds for TOMM7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TOMM7 lysates
     Search for Antibodies for TOMM7 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TOMM7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TOMM7 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TOMM7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TOMM7
     SwitchGear 3'UTR luciferase reporter plasmids for TOMM7
     SwitchGear Promoter luciferase reporter plasmids for TOMM7
     Search ThermoFisher Antibodies for TOMM7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM7
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TOMM7
    Sirion Biotech Customized:
     stable knockdown cell line services for TOMM7
     inducible knockdown cell line services for TOMM7
     design and validation of potent shRNA sequences against TOMM7
     adenovirus for potent knockdown of TOMM7
     adenovirus for overexpression of TOMM7
     stable overexpressing cell line services for TOMM7
     inducible overexpressing cell line services for TOMM7
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TOMM7 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4