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TOMM7 Gene

protein-coding   GIFtS: 51
GCID: GC07M022853

Translocase Of Outer Mitochondrial Membrane 7 Homolog (Yeast)

  Search for TOMM7
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Translocase Of Outer Mitochondrial Membrane 7 Homolog (Yeast)1 2
Translocase Of Outer Membrane 7 KDa Subunit Homolog2 3
TOM72 3
6.2 Kd Protein2
Mitochondrial Import Receptor Subunit TOM7 Homolog2
TOMM073

External Ids:    HGNC: 216481   Entrez Gene: 545432   Ensembl: ENSG000001966837   OMIM: 6079805   UniProtKB: Q9P0U13   

Export aliases for TOMM7 gene to outside databases

Previous GC identifers: GC07M022560 GC07M022594 GC07M022626 GC07M022818 GC07M022735


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TOMM7 Gene:
This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates
the assembly and stability of the translocase complex. (provided by RefSeq, Oct 2012)

GeneCards Summary for TOMM7 Gene:
TOMM7 (translocase of outer mitochondrial membrane 7 homolog (yeast)) is a protein-coding gene. GO annotations related to this gene include protein transmembrane transporter activity.

UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1
Function: Required for assembly and stability of the TOM complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007819.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the TOMM7 gene promoter:
         ISGF-3   LHX3b/Lhx3b   Pbx1a   POU3F1   Evi-1   E47   HFH-1   LHX3a/Lhx3a   Hand1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOMM7 promoter sequence
   Search Chromatin IP Primers for TOMM7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TOMM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.3   Ensembl cytogenetic band:  7p15.3   HGNC cytogenetic band: 7p15.3

TOMM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOMM7 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M022853:  view genomic region     (about GC identifiers)

Start:
22,852,251 bp from pter      End:
22,862,470 bp from pter
Size:
10,220 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 22,903,376-22,913,545     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1 (See protein sequence)
Recommended Name: Mitochondrial import receptor subunit TOM7 homolog  
Size: 55 amino acids; 6248 Da
Subunit: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which
consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70)
Secondary accessions: O95939

Explore the universe of human proteins at neXtProt for TOMM7: NX_Q9P0U1

Explore proteomics data for TOMM7 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys17
  • Modification sites at PhosphoSitePlus

  • See TOMM7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061932.1  
    ENSEMBL proteins: 
     ENSP00000351214   ENSP00000385203   ENSP00000361970  
    Reactome Protein details: Q9P0U1

    TOMM7 Human Recombinant Protein Products:

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    TOMM7 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR012621 Tom7

    Graphical View of Domain Structure for InterPro Entry Q9P0U1

    ProtoNet protein and cluster: Q9P0U1

    1 Blocks protein domain: IPB012621 TOM7

    UniProtKB/Swiss-Prot: TOM7_HUMAN, Q9P0U1
    Similarity: Belongs to the Tom7 family


    TOMM7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TOM7_HUMAN, Q9P0U1
    Function: Required for assembly and stability of the TOM complex

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12198123
    GO:0008320protein transmembrane transporter activity TAS15644312
         
    TOMM7 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TOMM7
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TOMM7
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TOMM7

    miRNA
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    miRTarBase miRNAs that target TOMM7:
    hsa-mir-615-3p (MIRT040020)

    Block miRNA regulation of human, mouse, rat TOMM7 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TOMM7
    SwitchGear 3'UTR luciferase reporter plasmidTOMM7 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TOMM7
    Predesigned siRNA for gene silencing in human, mouse, rat TOMM7

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: TOMM7 (NM_014820)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TOMM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM7

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOMM7


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TOM7_HUMAN, Q9P0U1: Mitochondrion outer membrane; Single-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA12198123
    GO:0005742mitochondrial outer membrane translocase complex IDA12198123
    GO:0016021integral component of membrane IEA--

    TOMM7 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TOMM7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Metabolism of proteins0.30
    2Mitochondrial Protein Import
    Mitochondrial Protein Import

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for TOMM7
        Mitochondrial protein import



    TOMM7 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TOMM7
    Interactions:

        Search GeneGlobe Interaction Network for TOMM7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TOMM7 (Q9P0U11, 3 ENSP000003512144) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TOMM22Q9NS691, 3, ENSP000002160344EBI-1180558,EBI-1047508 I2D: score=2 STRING: ENSP00000216034
    TOMM40O960083, ENSP000002524874I2D: score=2 STRING: ENSP00000252487
    CHCHD4ENSP000002957674STRING: ENSP00000295767
    DNAJC19ENSP000003720054STRING: ENSP00000372005
    GFERENSP000002481144STRING: ENSP00000248114
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006626protein targeting to mitochondrion TAS15644312
    GO:0030150protein import into mitochondrial matrix IEA--
    GO:0044267cellular protein metabolic process TAS--

    TOMM7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TOMM7 (TOM7)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TOMM7 gene: 
    NM_019059.3  

    Unigene Cluster for TOMM7:

    Translocase of outer mitochondrial membrane 7 homolog (yeast)
    Hs.112318  [show with all ESTs]
    Unigene Representative Sequence: CD048567
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000463284 ENST00000358435(uc003svk.3) ENST00000483581 ENST00000405021
    ENST00000372879 ENST00000496129
    miRNA
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    Block miRNA regulation of human, mouse, rat TOMM7 using miScript Target Protectors
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    Inhib. RNA
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    Primer
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    OriGene qPCR primer pairs and template standards for TOMM7
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TOMM7
      QuantiTect SYBR Green Assays in human, mouse, rat TOMM7
      QuantiFast Probe-based Assays in human, mouse, rat TOMM7

    Additional mRNA sequence: 

    AF086336.1 AF150733.1 AJ011007.1 AK026520.1 BC001732.1 BC071973.1 CR456960.1 

    15 DOTS entries:

    DT.100861392  DT.87017313  DT.102829396  DT.100689421  DT.120878158  DT.100806946  DT.100057581  DT.100009074 
    DT.121049623  DT.87001802  DT.92475107  DT.40286998  DT.95288390  DT.100891992  DT.121049619 

    Selected AceView cDNA sequences (see all 652):

    N41855 BE391434 AA654904 F27385 CA866806 BU951799 BQ673586 AA385602 
    BC001732 BF025770 AA320314 AA640125 AW772838 F31347 BM849294 BM738805 
    BM840487 BQ935404 AA635536 F31370 BQ683453 BU191705 BG760143 BM764622 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TOMM7    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b
    SP1:                          -     -               
    SP2:                          -                     
    SP3:                    -     -     -               
    SP4:                                                


    ECgene alternative splicing isoforms for TOMM7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TOMM7 expression in normal human tissues (normalized intensities)      TOMM7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGATGTGT
    TOMM7 Expression
    About this image


    TOMM7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Ovary (Reproductive System)
             Ovarian Somatic Cells Ovigerous Cord
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Tonsil (Hematopoietic System)
    TOMM7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TOMM7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.112318
        Custom PCR Arrays for TOMM7
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOMM7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TOMM7 gene from 12 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia TOMM71 translocase of outer mitochondrial membrane 7 homolog more 98.79(n)
    98.18(a)
      746464  XM_001153870.3  XP_001153870.2 
    mouse
    (Mus musculus)
    Mammalia Tomm71 , 5 translocase of outer mitochondrial membrane 7 homolog more1, 5 90.3(n)1
    94.55(a)1
      5 (10.48 cM)5
    661691  NM_025394.31  NP_079670.11 
     238389445 
    rat
    (Rattus norvegicus)
    Mammalia Tomm71 translocase of outer mitochondrial membrane 7 homolog more 89.7(n)
    94.55(a)
      685620  NM_001135174.1  NP_001128646.1 
    cow
    (Bos taurus)
    Mammalia TOMM71 translocase of outer mitochondrial membrane 7 homolog more 92.12(n)
    98.18(a)
      614074  NM_001113306.2  NP_001106777.1 
    dog
    (Canis familiaris)
    Mammalia TOMM71 translocase of outer mitochondrial membrane 7 homolog more 90.3(n)
    98.18(a)
      482351  XM_539468.4  XP_539468.3 
    oppossum
    (Monodelphis domestica)
    Mammalia TOMM76
    translocase of outer mitochondrial membrane 7 homo...
    65(a)
    1 ↔ 1
    8(300855666-300857690)
    platypus
    (Ornithorhynchus anatinus)
    Mammalia TOMM76
    translocase of outer mitochondrial membrane 7 homo...
    95(a)
    1 ↔ 1
    Ultra65(883118-892273)
    chicken
    (Gallus gallus)
    Aves TOMM71 translocase of outer mitochondrial membrane 7 homolog more 80.61(n)
    87.27(a)
      420610  NM_001199617.1  NP_001186546.1 
    lizard
    (Anolis carolinensis)
    Reptilia TOMM76
    translocase of outer mitochondrial membrane 7 homo...
    84(a)
    1 ↔ 1
    6(30312298-30321818)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253772 Xenopus laevis transcribed sequence with moderate similarity more 73.74(n)    BJ051727.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tomm76
    translocase of outer mitochondrial membrane 7 homo...
    82(a)
    1 ↔ 1
    19(3109049-3118843) ENSDARG00000067717
    rainbow trout
    (Oncorhynchus mykiss)
    Actinopterygii BX319980.12   -- 72.68(n)    BX319980.1 
            Species with no ortholog for TOMM7

    ENSEMBL Gene Tree for TOMM7 (if available)
    TreeFam Gene Tree for TOMM7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TOMM7 gene
    1 SIMAP similar gene for TOMM7 using alignment to 3 protein entries:     TOM7_HUMAN (see all proteins):
    TOM7

    TOMM7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for TOMM7
    PGOHUM00000245628 PGOHUM00000235547


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TOMM7 (see all 311)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs732782661,2
    C,F--22851877(+) CCCAAC/TAGGCT 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs171472901,2
    C,F,H--22851967(+) TAGAAG/AAACGG 1 -- ds50018Minor allele frequency- A:0.15NA NS WA EA 694
    rs1812107961,2
    --22851970(+) AAGAAC/TGGAAA 1 -- ds50010--------
    rs1866662791,2
    --22851989(+) TAATAA/GAAGTA 1 -- ds50010--------
    rs1449771291,2
    --22852049(+) AACTAC/GTTTCC 1 -- ds50010--------
    rs1125994041,2
    C--22852424(+) AAAAAT/ATTTTT 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs778936811,2
    C,F--22852436(+) ATATCG/ATGATC 1 -- ut311Minor allele frequency- A:0.06WA 118
    rs22407281,2
    C,F--22852499(-) TGTGTA/GTACCT 1 -- ut31 ese312Minor allele frequency- G:0.42NA WA CSA EA 376
    rs22407271,2
    C,F,H--22852512(-) AACAGA/GGAATT 1 -- ut31 ese323Minor allele frequency- G:0.45EA NS NA WA CSA 3832
    rs1118246911,2
    C--22852591(+) AGCATA/TACACT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TOMM7 (22852251 - 22862470 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for TOMM7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv272529CNV Insertion20981092
    esv269276CNV Insertion20981092
    esv2467344CNV Insertion19546169
    nsv526131CNV Loss19592680
    dgv2070e1CNV Complex17122850
    nsv7393OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607980    OMIM disorders: --


    TOMM7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TOMM7
    Human Genome Epidemiology (HuGE) Navigator: TOMM7 (2 documents)

    Export disorders for TOMM7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TOMM7 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with TOMM7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane. (PubMed id 12198123)1, 2, 3 Johnston A.J.... Ryan M.T. (J. Biol. Chem. 2002)
    2. Cloning and characterization of the human novel gene encoding 6.2 kDa protein highly expressed upon ultraviolet irradiation in DNA-PK- deleted human glioma M059J cells. (PubMed id 10647823)1, 2, 3 Lee J.-S. (DNA Seq. 1999)
    3. Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane. (PubMed id 18331822)1, 2, 9 Kato H. and Mihara K. (Biochem. Biophys. Res. Commun. 2008)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. Multiethnic meta-analysis of genome-wide association studies in &gt;100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. (PubMed id 23969696)1 Sabater-Lleal M....O'Donnell C.J. (Circulation 2013)
    10. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54543 HGNC: 21648 AceView: TOMM7 Ensembl:ENSG00000196683 euGenes: HUgn54543
    ECgene: TOMM7 H-InvDB: TOMM7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TOMM7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TOMM7 gene:
    Search GeneIP for patents involving TOMM7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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