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TOMM40L Gene

protein-coding   GIFtS: 50
GCID: GC01P161195

Translocase Of Outer Mitochondrial Membrane 40 Homolog (Yeast)-Like

(Previous name: translocase of outer mitochondrial membrane 40 homolog-like...)
  Search for TOMM40L
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Translocase Of Outer Mitochondrial Membrane 40 Homolog (Yeast)-Like1 2
Protein TOMM40-Like2 3
TOMM40B2 3
Translocase Of Outer Mitochondrial Membrane 40 Homolog-Like (Yeast)1
Mitochondrial Import Receptor Subunit TOM40B2
Translocase Of Outer Mitochondrial Membrane 40 Homolog-Like2

External Ids:    HGNC: 257561   Entrez Gene: 841342   Ensembl: ENSG000001588827   UniProtKB: Q969M13   

Export aliases for TOMM40L gene to outside databases

Previous GC identifers: GC01P158009 GC01P159462 GC01P132552


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TOMM40L Gene:
TOMM40L (translocase of outer mitochondrial membrane 40 homolog (yeast)-like) is a protein-coding gene. GO annotations related to this gene include porin activity. An important paralog of this gene is TOMM40.

UniProtKB/Swiss-Prot: TM40L_HUMAN, Q969M1
Function: Potential channel-forming protein implicated in import of protein precursors into mitochondria (By
similarity)

Gene Wiki entry for TOMM40L Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TOMM40L gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   LCR-F1   C/EBPalpha   CREB   E2F   E2F-1   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTOMM40L promoter sequence
   Search Chromatin IP Primers for TOMM40L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TOMM40L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.3

TOMM40L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TOMM40L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P161195:  view genomic region     (about GC identifiers)

Start:
161,195,793 bp from pter      End:
161,200,408 bp from pter
Size:
4,616 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM40L_HUMAN, Q969M1 (See protein sequence)
Recommended Name: Mitochondrial import receptor subunit TOM40B  
Size: 308 amino acids; 33917 Da
Subunit: Forms part of the preprotein translocase of the outer mitochondrial membrane (TOM complex) containing
TOMM22, TOMM40, TOMM40L and TOMM70. Interacts with mitochondrial targeting sequences (By similarity)
Secondary accessions: D3DVG9

Explore the universe of human proteins at neXtProt for TOMM40L: NX_Q969M1

Explore proteomics data for TOMM40L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TOMM40L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273302.1  NP_001273303.1  NP_115550.2  

    ENSEMBL proteins: 
     ENSP00000356967   ENSP00000356966   ENSP00000443233  

    TOMM40L Human Recombinant Protein Products:

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    OriGene Purified Protein for TOMM40L
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    Novus Biologicals TOMM40L Protein
    Novus Biologicals TOMM40L Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TOMM40L

     
    Search eBioscience for Proteins for TOMM40L 

    TOMM40L Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for TOMM40L

    TOMM40L Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TOMM40L
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    Search eBioscience for ELISAs for TOMM40L 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR027246 Porin_Euk/Tom40
     IPR023614 Porin_dom

    Graphical View of Domain Structure for InterPro Entry Q969M1

    ProtoNet protein and cluster: Q969M1

    UniProtKB/Swiss-Prot: TM40L_HUMAN, Q969M1
    Similarity: Belongs to the Tom40 family


    Find genes that share domains with TOMM40L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM40L_HUMAN, Q969M1
    Function: Potential channel-forming protein implicated in import of protein precursors into mitochondria (By
    similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0015288porin activity IEA--
         
    Find genes that share ontologies with TOMM40L           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TOMM40L:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TOMM40L
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TOMM40L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TOMM40L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TOMM40L

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TOMM40L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TOMM40L (see all 28):
    hsa-miR-148b* hsa-miR-875-3p hsa-miR-4286 hsa-miR-185* hsa-miR-330-5p hsa-miR-877* hsa-miR-4314 hsa-miR-654-5p
    SwitchGear 3'UTR luciferase reporter plasmidTOMM40L 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TOMM40L
    Predesigned siRNA for gene silencing in human, mouse, rat TOMM40L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TOMM40L

    Clone
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    OriGene clones in human, mouse for TOMM40L (see all 7)
    OriGene ORF clones in mouse, rat for TOMM40L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TOMM40L (NM_032174)
    Sino Biological Human cDNA Clone for TOMM40L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TOMM40L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM40L

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOMM40L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM40L_HUMAN, Q969M1: Mitochondrion outer membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol1
    extracellular1
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005741mitochondrial outer membrane IEA--
    GO:0043234protein complex IDA--
    GO:0046930pore complex IEA--

    Find genes that share ontologies with TOMM40L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TOMM40L About    
    See pathways by source

    SuperPathContained pathways About
    1Amyotrophic lateral sclerosis (ALS)
    Amyotrophic lateral sclerosis (ALS)0.63


    Find genes that share SuperPaths with TOMM40L           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for TOMM40L):
        Amyotrophic lateral sclerosis (ALS)

        Pathway & Disease-focused RT2 Profiler PCR Array including TOMM40L: 
              Mitochondria in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TOMM40L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TOMM40L (ENSP000003569664) via UniProtKB, MINT, STRING, and/or I2D (see all 65)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARHGEF10LENSP000003550604STRING: ENSP00000355060
    ATPAF1ENSP000003610054STRING: ENSP00000361005
    C1orf146ENSP000003594014STRING: ENSP00000359401
    ENSG00000184494ENSP000002297254STRING: ENSP00000229725
    ENSG00000206501ENSP000003731074STRING: ENSP00000373107
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811ion transport IEA--
    GO:0008150biological_process ND--
    GO:0015031protein transport IEA--
    GO:0055085transmembrane transport ----

    Find genes that share ontologies with TOMM40L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TOMM40L (TM40L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TOMM40L gene (3 alternative transcripts): 
    NM_001286373.1  NM_001286374.1  NM_032174.5  

    Unigene Cluster for TOMM40L:

    Translocase of outer mitochondrial membrane 40 homolog (yeast)-like
    Hs.321653  [show with all ESTs]
    Unigene Representative Sequence: BX537951
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367988(uc010pkk.1 uc010pkl.1 uc001fzd.3 uc009wue.3 uc009wuf.2)
    ENST00000474486 ENST00000470426 ENST00000465512 ENST00000492482 ENST00000367987(uc001fze.3)
    ENST00000468803 ENST00000475793 ENST00000545897
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TOMM40L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TOMM40L (see all 28):
    hsa-miR-148b* hsa-miR-875-3p hsa-miR-4286 hsa-miR-185* hsa-miR-330-5p hsa-miR-877* hsa-miR-4314 hsa-miR-654-5p
    SwitchGear 3'UTR luciferase reporter plasmidTOMM40L 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TOMM40L
    Predesigned siRNA for gene silencing in human, mouse, rat TOMM40L
    Clone
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    OriGene clones in human, mouse for TOMM40L (see all 7)
    OriGene ORF clones in mouse, rat for TOMM40L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TOMM40L (NM_032174)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TOMM40L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TOMM40L
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TOMM40L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TOMM40L
      QuantiTect SYBR Green Assays in human, mouse, rat TOMM40L
      QuantiFast Probe-based Assays in human, mouse, rat TOMM40L

    Additional mRNA sequence: 

    AK022832.1 AK027704.1 AK297831.1 AK297848.1 BC014946.1 BX537951.1 

    15 DOTS entries:

    DT.118466  DT.100764886  DT.121424518  DT.100837321  DT.121424515  DT.121424509  DT.100743821  DT.92431328 
    DT.92431329  DT.95275300  DT.121424572  DT.95275299  DT.100764884  DT.121424516  DT.75170204 

    Selected AceView cDNA sequences (see all 151):

    BU149549 AK022832 CB305777 BM917040 AA594687 CB989817 AI081566 AI096402 
    BQ053725 BU168678 AI080696 BM904090 BM696582 AW028065 BQ681335 AA447727 
    Z45632 BE262030 BQ684804 BC014946 Z38960 AK027704 BM793386 CA448384 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TOMM40L    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                                    
    SP2:                                                                                    
    SP3:                                                                                    
    SP4:        -                                                                           


    ECgene alternative splicing isoforms for TOMM40L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TOMM40L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCACACAAAG
    TOMM40L Expression
    About this image

    TOMM40L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TOMM40L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.321653
        Pathway & Disease-focused RT2 Profiler PCR Array including TOMM40L: 
              Mitochondria in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TOMM40L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TOMM40L gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tomm40l1 , 5 translocase of outer mitochondrial membrane 40 homolog-like more1, 5 92.1(n)1
    97.73(a)1
      1 (79.22 cM)5
    6413761  NM_001037170.21  NP_001032247.11 
     1712178025 
    chicken
    (Gallus gallus)
    Aves TOMM40L6
    translocase of outer mitochondrial membrane 40 hom...
    76(a)
    1 ↔ 1
    JH375544.1(2180-5143)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tomm40l1 translocase of outer mitochondrial membrane 40 homolog more 70.28(n)
    72.29(a)
      100496551  XM_002941151.2  XP_002941197.2 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-71l1.11 si:dkey-71l1.1 63.37(n)
    62.12(a)
      569883  NM_001114438.1  NP_001107910.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta tomboy406
    Tom406
    (see all 3)
    Translocase of outer membrane 40
    (see all 3)
    39(a)
    37(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    2R(2113132-2114389)
    X(7630926-7634011)
    worm
    (Caenorhabditis elegans)
    Secernentea tomm-406
    Protein TOMM-40 (tomm-40) mRNA, complete cds
    41(a)
    1 → many
    II(8971958-8973566) WBGene00007686
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TOM40(YMR203W)4 Component of the TOM (translocase of outer membrane) more   --   13(668492-669655) 855243  NP_013930.1 


    ENSEMBL Gene Tree for TOMM40L (if available)
    TreeFam Gene Tree for TOMM40L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TOMM40L gene
    TOMM402  
    1 SIMAP similar gene for TOMM40L using alignment to 3 protein entries:     TM40L_HUMAN (see all proteins):
    TOMM40

    Find genes that share paralogs with TOMM40L           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TOMM40L (see all 67)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0358154
    A colorectal cancer sample4--see VAR_0358152 D N mis40--------
    rs1890464981,2
    C--161197014(+) AGGAAG/TGCGCT 1 -- int10--------
    rs793891821,2
    C--161197734(+) ACTACA/CCAGCC 2 T P mis10--------
    rs1460963181,2
    --161197734(+) CTACA-/CCC   
       CCCCC
    CAGCC
    2 A PPQ fra10--------
    rs741246761,2
    C,F--161197788(+) AGGAAC/GTGGGA 1 -- int13Minor allele frequency- G:0.11WA CSA 122
    rs2007642431,2
    C--161197789(+) GGAACG/TGGGAC 1 -- int10--------
    rs1995091471,2
    --161197806(+) CTTTTC/TATCTT 1 -- int10--------
    rs1814953481,2
    --161197848(+) TTCATC/TTTCTG 1 -- int10--------
    rs741246781,2
    C--161197889(+) TGGGCA/GGGCTG 1 -- int12Minor allele frequency- G:0.10WA 120
    rs1390362961,2
    --161197919(+) TGAGGG/TAGCAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for TOMM40L (161195793 - 161200408 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TOMM40L: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TOMM40L
    DNA2.0 Custom Variant and Variant Library Synthesis for TOMM40L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    Find genes that share disorders with TOMM40L           About GenesLikeMe

    Genetic Association Database (GAD): TOMM40L
    Human Genome Epidemiology (HuGE) Navigator: TOMM40L (1 document)

    Export disorders for TOMM40L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TOMM40L gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with TOMM40L)
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    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    8. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84134 HGNC: 25756 AceView: FLJ12770 Ensembl:ENSG00000158882 euGenes: HUgn84134
    ECgene: TOMM40L Kegg: 84134 H-InvDB: TOMM40L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TOMM40L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TOMM40L gene:
    Search GeneIP for patents involving TOMM40L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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